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"Demam neutropenia merupakan efek samping yang sering terjadi setelah kemoterapi. Demam neutropenia dapat menyebabkan penundaan dosis kemoterapi sehingga dapat mengurangi efektivitas terapi. Kejadian demam neutropenia paskakemoterapi dapat dicegah dengan pemberian Granulocyte-colony Stimulating Factor (G-CSF). Regimen kemoterapi yang digunakan dapat memengaruhi kejadian demam neutropenia. Selain itu, usia, stadium kanker, riwayat kemoterapi dan kadar hemoglobin sebelum kemoterapi merupakan faktor risiko demam neutropenia paskakemoterapi.Penelitian ini bertujuan untuk mengetahui perbandingan kejadian demam neutropenia regimen TAC (dosetaksel, doksorubisin, siklofosfamid) dengan profilaksis primer G-CSF dan regimen FAC (fluorourasil, doksorubisin, siklofosfamid) pada pasien kanker payudara di RSUP Dr. Hasan Sadikin Bandung periode Januari 2017-Juni 2019.Desain penelitian adalah cross sectional uji dua populasi. Jumlah sampel sebanyak 61 regimen TAC dan 102 regimen FAC. Kejadian demam neutropenia dianalisis menggunakan chi-square.Hasil penelitian menunjukkan kejadian demam neutropenia paskakemoterapi lebih banyak terjadi pada regimen TAC dengan profilaksis primer G-CSF dibandingkan dengan regimen FAC. Kejadian demam neutropenia 12 kali lebih banyak terjadi pada regimen TAC dengan GCSF dibanding regimen FAC. Usia, stadium kemoterapi, riwayat kemoterapi dan kadar hemoglobin sebelum kemoterapi secara statistik tidak signifikan memengaruhi kejadian demam neutropenia paskakemoterapi.

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Febrile Neutropenia is a common side effect of chemotherapy. Febrile neutropenia can cause delayed chemo doses that can reduce the effectiveness of therapy. The incidence of febrile neutropenia can be prevented by administering Granulocyte-colony Stimulating Factor (G-CSF). The chemotherapy regimen can affect the incidence of febrile neutropenia. In addition, age, stage of cancer, history of chemotherapy and prechemotherapy hemoglobin level are risk factors for febrile neutropenia.This study aimed to compare the incidence of febrile neutropenia between TAC (docetaxel, doxorubicin, cyclophosphamide) regimen with G-CSF primary prophylaxis and FAC regimen (fluorouracil, doxorubicin, cyclophosphamide) in breast cancer patients at RSUP Dr. Hasan Sadikin Bandung period January 2017 - June 2019.The study design was cross sectional test of two populations. The sample consisted of 61 TAC regimen and 102 FAC regimen. The incidence of febrile neutropenia were analyzed using chi-square.The results showed that the incidence of post-chemotherapy febrile neutropenia is more common in TAC regimen with G-CSF primary prophylaxis than FAC regimen. The incidence of neutropenia is 12 times more common in TAC regimens with G-CSF than FAC regimen. Age, stage of chemotherapy, history of chemotherapy and pre-chemotherapy hemoglobin levels did not statistically significantly influence the incidence of febrile neutropenia."

"Kemoterapi sering menimbulkan kecemasan, mual dan muntah. Salah satu tindakan nonfarmakologis untuk mengatasi kecemasan,mual dan muntah setelah kemoterapi adalah dengan relaksasi Progressive Muscle Relaxation (PMR).Tujuan penelitian ini adalah mengidentifikasi pengaruh PMR terhadap kecemasan, mual, dan muntah setelah kemoterapi pada kanker payudara di RS Dr. Hasan Sadikin Bandung. Metoda penelitian quasi experiment.Rancangan penelitian yang digunakan adalah pre and post test group design dengan kelompok kontrol. Sampel berjumlah 70 orang. Teknik pengambilan sampel consecutive sampling. Alat yang digunakan kuesioner kecemasan State and Trait dan Morrow Assesment Nausea and Emesis (MANE) untuk mengukur mual dan muntah. Kelompok intervensi diberikan relaksasi dengan Progressive Muscle Relaxation (PMR) sehari dua kali selama satu minggu post kemoterapi (dua siklus kemoterapi) atau secara total, subjek melakukan 28 kali relaksasi dengan PMR.Untuk menguji perbedaan rata-rata skor kecemasan, mual, dan muntah pada kelompok kontrol dan intervensi digunakan uji T.Hasil penelitian usia, tingkat pendidikan, dan siklus kemoterapi setara. Selisih Penurunan rata-rata kecemasan, mual, dan muntah sebelum dan setelah PMR pada kelompok intervensi berbeda secara bermakna (p value=0,000).Kesimpulan PMR dapat menurunkan kecemasan, mual, dan muntah setelah kemoterapi pada pasien kanker payudara di RS. Dr. Hasan Sadikin Bandung. Disarankan PMR diterapkan di rumah sakit sebagai salah satu terapi komplementer nonfarmakologik untuk mengatasi kecemasan, mual, dan muntah, dibuat sebagai prosedur tetap dalamintervensi keperawatan.

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ABSTRACTChemotherapy often causes anxiety, nausea and vomiting. One of the complementary therapy nonfarmacological procedures to overcome post-chemotherapy anxiety, nausea, and vomiting is Progressive Muscle Relaxation (PMR).The objective of the research is to identify impact of PMR on anxiety impact of PMR on anxiety, nausea, and vomiting after chemotherapy for breast cancer at Dr. Hasan Sadikin Hospital in Bandung. The research method was a quasi experimental.The research design was pre and post groups design with a control. The number of the sample participated in the study was 70 persons. The sample collection technique used was a consecutive sampling. One quesionare was utilized the State and Trait and the Morrow Assessment Nausea and Emesis (MANE) to measure nausea and vomiting. The intervention group was treated with PMR twice a day for one week post chemotherapy (two cycle of chemotherapy) or subjek was relaxation with PMR for 28 times, totally. To test the average difference in scores of anxiety, nausea, and vomiting in in the control and the intervention groups, a ttest was used.The research result demonstrated tha the age, education, and the chemotherapy cicle is equal.the average scores of anxiety, nausea, and vomiting before and after PMR in the intervention groups decreases significantly (pvalue=0,000). It is conclude that PMR can reduce anxiety, nausea, and vomiting after chemotherapy among patient with breast cancer at Dr. Hasan Sadikin Hospital in Bandung.It is recommended that PMR should be used in hospitals as a complementary therapy to overcome anxiety, nausea, and vomiting nonpharmacologicaly. In addition, a recommendation also directed to the management of hospital to include PMR as a standard nursing procedure."

"Sekitar 490.000 perempuan di seluruh dunia didiagnosa menderita kanker serviks danrata-rata 240.000 kasus kematian perempuan terjadi akibat kanker serviks dan hampir80% dari kasus tersebut terjadi di negara-negara berkembang (WHO, 2008). Nyerimerupakan keluhan terbanyak yang dirasakan penderita kanker. Seperti halnya dikatakanoleh Abernethy, Keefe, McCrory, Scipio, (2006), angka kejadian nyeri pada semuapasien kanker sekitar 25% pada kanker yang baru terdiagnosa dan sekitar 60% sampaidengan 90% pada kanker stadium lanjut. Dodd, Miaskowski, dan Paul (2001)mengidentifikasi terjadinya nyeri pada pasien dengan kanker yang mendapatkankemoterapi. Tujuan :dari penelitian ini mendapatkan gambaran efektifitas Brief CBTterhadap nyeri dengan menggunakan instrumen Numeric Rating Scale (NRS) dan PerceivedMeaning Cancer Pain Inventory (PMCPI). Metoda : quasi experimental pre post test withcontrol group, teknik consecutive sampling terhadap 51 sampel : 26 intervensi dan 25kontrol. Hasil penelitian ditemukan penurunan intensitas nyeri dan PMCPI yang mendapatCBT lebih besar dibanding yang tidak mendapat CBT (p-value < 0,05). Rekomendasi: BriefCBT dijadikan terapi terpadu dalam manajemen nyeri pada pasien kanker serviks.

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Approximately 490,000 women worldwide are diagnosed with cervical cancer and

anaverage of 240,000 female deaths occur from cervical cancer and nearly 80% of these

cases occur in developing countries (WHO, 2008). Pain is a complaint that is felt most

cancer patients. As well said by Abernethy, Keefe, McCrory, Scipio, (2006), the incidence

of pain in all cancer patients about 25% in the newly diagnosed cancers and approximately

60% to 90% in advanced cancer. Dodd, Miaskowski, and Paul (2001) identified the

occurrence of pain in patients with cancer receiving chemotherapy. The purpose: to get an

overview of the research on the effectiveness of brief CBT pain using instruments Numeric

Rating Scale (NRS) and Perceived Meanings Cancer Pain Inventory (PMCPI). Method:

quasi-experimental pre-post test with control group, 51 consecutive sampling technique to

sample: 26 intervention and 25 control. The results found reductions in pain intensity and

PMCPI that gets bigger than that CBT did not receive CBT (p-value <0,05).

Recommendation: Brief CBT therapy be integrated in the management of pain in patients

with cervical cancer."

"Penanganan pasangan ingin anak membutuhkan kesabaran dari pihak medis maupun pasien di samping kemampuan mendiagnosa serta pengobatan yang terarah. RSUP Dr. Hasan Sadikin mempunyai kelompok kerja ART (Assisted Reproduktif Technology) dengan surat keputusan Direktur Nomor: Kp 01.01.1.2.231.P tanggal 20 Nopember 1995, untuk mengembangkan Tim Ahli Bayi Tabung di Seksi Infertilitas SMF Kebidanan dan Penyakit Kandungan. Kememapuan penangann pasangan infertil di RSUP Dr. Hasan Sadikin masih jauh dari memadai, karena keterbatasan sarana, sedangkan kebutuhan akan pelayanan ART sudah mendesak. Penelitian ini dilakukan dengan tujuan memperoleh gambaran trend pelayanan infertilitas di RSUP Dr. Hasan Sadikin dan memilih model strategis yang tepat untuk di terapkan. Penelitian ini adalah operasional riset yang dianalisis secara kuantitatif dan kualitatif. Hasil penelitian dari analisia situasi menggambarkan total jumlah kunjungan pelayanan mengalami penurunan sekitar 19,21% dan dari total jumlah kasus, 87% kasus usia di bawah 35 tahun potensi untuk ditangani tuntas dan 67% kasuss memerlukan tindakan ART, pada periode tahun 1993-1997. Hasil analisis metode Dekamposisi menggambarkan faktor trend kunjungan menurun, sehingga sulituntukmerencanakan sasaran jangka panjang, dan Indeks Musim.memperlihatkan peningkatan hanya pada bulan Januari, Maret, Mai, Juni, Nopember dan Desember, sehingga baru dapat mereucanakan sasaran jangka pendek di pelayananinfertilitas. Hasil analisis metode Delphi menggambarkan derajat pelaksanaan rendah, akselerasi pelayanan lamban, adanya factor pendorong dan penghambat pelaksanaan serta masalah keuangan sebagai faktor kekuatan, kelemahan, ancaman dan peluang Seksi Pelayanan Infertilitas. Hasil analisis matrike SPACE dalam memposisikan strategi sebagai langkah awal pemilihan model strategi, yaitu pada Kuadran I: Agresif adalah pertumbuhan dan perkembangan. Pada penelitian ini dibahas dua strategi alternatif untuk memilih model strategi yang tepat, yaitu strategi umum/bisnis dan strategi operasional. Untuk mengembangkan pelayanan infertilitas di RSUP Dr. Hasan Sadikin saat ini dipilih strategi operasional dengan sasaran elemen kunci pengembangan di bidang pemasaran, keuangan, produksi/operasi, riset dan pengembangan, sumber daya manusia serta konsisten dengan target lahir bayi tabung, sehingga. dapat disusun program kerja berdasarkan pendekatan legislatif, edukatif, ekonomi, administratif dan teknis.

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Managing couples wishing to have children needs patience from the medical services as well as the patient besides ability to diagnose and well planned medical treatment. Dr. Hasan Sadikin Provincial Hospital developed has an ART (Assisted Reproductive Technology) team work through the Director's Decree: Kp. 01.01.2. 231.P date 20'h November 1995. This Team of Experts of Test-tube Babies at the Infertility Division, Obstetrics and Gynecology Department is developing it capability in managing infertile couples at Dr. Hasan Sadikin Provincial Hospital, however it still far from adequate, due to limited facilities, while the need for ART services is already urgently field.

This is an operational research study, utilizing quantitative and qualitative analysis, aiming at obtaining the trend of the infertility service demand at Dr. Hasan Sadikin Provincial Hospital, and selecting a correct strategy model to be applied.

The situational analysis of this study revealed for that a period of 1993-1997 there was a decrease of around 19,21% in the total number of visits; in which, 87 % of the cases of those under 35 years of age and were potential for complete treatment, while 67% of the cases needed an ART management.

Analysis by decomposition method revealed that the trend factor decreased, so that it was difficult to plan for a long term target, and that the season Index showed an increase only in the months of January, March, May, June, November, and December, so that only a short term plan could be planned in the infertility services.

Analysis by the Delphi method revealed a low level of implementation, a slow acceleration of service, the presence of enchancing and delaying factors in the implementation, and also financial problems as factors of strength, weakness, threat, and opportunity in the infertility services.

Result of SPACE matrix analysis in positioning strategy as an initial step in the selection of a strategy model, is as follows Quadrant I: Aggressive is growth and development.

In this study two alternative strategies were analyzed to choose the right strategy model, i.e. general business strategy and operational strategy to develop the infertility services at Dr. Hasan Sadikin Provincial Hospital. At present the operational strategy was selection with the development key element as the target in the aspect of marketing, finance, production/operation, research and development, human resources, and consistent with the birth of test-tube babies as target, so as to allow the compilation of a working program based on a legislative, educative, economic, administrative, and technical approach."

"Penelitian ini membahas hubungan antara kualitas layanan, kepuasan, dan loyalitas pasien. Penelitian ini adalah penelitian kuantitatif dengan desain studi cross-sectional. Responden berjumlah 96 orang dan merupakan pasien yang harus melakukan kunjungan ulang. Hasil analisis statistik menunjukkan tidak terdapat hubungan antara penilaian kualitas layanan dengan karakteristik pasien (p-value > 0,05). Tidak terdapat hubungan antara kepuasan dengan karakteristik pasien (pvalue > 0,05). Tidak terdapat hubungan antara loyalitas pasien dengan karakteristik pasien (p-value > 0,05). Terdapat hubungan antara kualitas layanan dengan kepuasan pasien (p-value = 0,000).Terdapat hubungan antara kepuasan dengan loyalitas pasien (p-value = 0,0002). Terdapat hubungan antara kualitas layanan dengan loyalitas pasien (p-value = 0,037). Kembalinya pasien dapat dikarenakan kepercayaan terhadap dokter. Tidak kembalinya pasien dapat dikarenakan pasien kecewa pada pelayanan atau beralih ke sarana pelayanan lain.

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This research discussed the relationship of service quality, satisfaction, and patient loyalty. This was a quantitative research with cross-sectional design of study. Data was acquired from 96 respondents who were required to do control by physician. Statistical findings demonstrated that there was no difference of satisfaction service quality with patient's characteristics (p-value > 0,05). There was no difference of satisfaction with patient's characteristics (p-value > 0,05). There was no difference of patient loyalty with patient's characteristics (p-value > 0,05). There was relationship between each dimension of service quality with patient's (p-value > 0.000). There was relationship between of satisfaction with patient loyalty (p-value > 0.0002). There was relationship between service quality with patient loyalty (p-value > 0.037). Actual return behavior could be influenced by the patient's trust to physician. Unreturned behavior of patient due to disappointment ni service quality or switch to another service of facility."

"ABSTRAKOSA dapat memperberat komplikasi CAD. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan risiko terjadinya OSA pada pasien CAD. Penelitian ini menggunakan rancangan Cross Sectional. Responden berjumlah 161 orang. Pengukuran risiko OSA menggunakan kuesioner. Dari hasil analisis data ditemukan ada hubungan yang signifikan antara jenis kelamin, riwayat keluarga, IMT, hipertensi, diabetes melitus, lingkar leher dan lingkar perut dengan risiko terjadinya OSA, sedangkan umur dan dislipidemia tidak berhubungan. Faktor yang paling berhubungan adalah IMT, Diabetes Melitus dan lingkar perut. Rekomendasi: Deteksi dini risiko terjadinya OSA sangat diperlukan bagi pasien CAD.

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ABSTRACTOSA can give complicated burdens on CAD. This research aimed at indentifying factors which relate to risks of the occurrence of OSA on patients with CAD. This research employed Cross Sectional Design. The total of respondents were 161 respondents. The measurement of OSA risks was conducted using questionnaires. The result of data analyse identified that there is a significant correlation among sex, history of family, IMT, hypertension, Diabetic mellitus, circle of neck and belly with the risks of OSA occurrence, whereas, the age and dislipidemia do not have correlation with the evidence of OSA. The most significant correlated factors are IMT, Diabetic mellitus and the circle of belly. Recommendation reveals that screening on the risks of OSA occurrence is needed for CAD patients."

"Anemia merupakan akibat sekunder dari Gagal Ginjal Terminal (GGT) yang terjadi pada 80-95% pasien, seiring dengan penurunan laju filtrasi glomerulus pada pasien hemodialisis. Tujuan penelitian untuk mengidentifikasi faktor-faktor yang berhubungan dengan anemia pada pasien hemodialisis rutin. Penelitian ini menggunakan desain cross sectional dengan jumlah sampel 116 orang.Hasil penelitian menunjukkan penyakit inflamasi merupakan faktor yang paling berhubungan dengan anemia ( p = 0,05; OR = 2,7), kedua adekuasi hemodialisis (p = 0,04; OR = 2,3) dan ketiga status nutrisi (p = 0,04; OR = 0,31). Pelaksanaan asuhan keperawatan yang komprehensif dan peran perawat dalam memastikan adekuasi hemodialisis tercapai untuk setiap pasien dengan frekuensi dialisis 3x/minggu selama 4 - 5 jam/sesi hemodialisis merupakan kunci keberhasilan manajemen anemia sebagai salah satu indikator kualitas pelayanan ruang hemodialisis.

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Anemia is a secondary effect of Chronic Renal Failure (CRF), which occurs in 80-95% of patients, in line with the decline of glomerular filtration rate. The purpose of this research was to identify the factors associated with anemia in hemodialysis patient. This study used cross-sectional design with a sample of 116 people.Results showed inflammatory disease was the most influential factor on the incidence of anemia (p = 0.05, OR = 2.7), then the adequacy of hemodialysis (p = 0.04; OR = 2.3) and third nutritional status (p = 0.04; OR = 0.31). Implementation of comprehensive nursing care and the role of nurses ensure adequacy of hemodialysis is achived for each patient with the frequency of hemodialysis performed 3 times a week for 4-5 hour per session of hemodialysis is the key indicator of adequacy of treatment of anemia as a service quality hemodialysis."

"Terapi musik merupakan salah satu terapi komplementer pada anak yang mengalami mual muntah lambat akibat kemoterapi. Mual muntah lambat merupakan efek yang paling menimbulkan stres pada anak dan keluarga. Tujuan penelitian untuk mengidentifikasi pengaruh terap musik terhadap mual muntah lambat pada anak usia sekolah dengan kanker. Desain penelitian adalah kuasi eksperimen dngan pre-post test control design.Hasil penelitian menunjukkan perbedaan mual muntah setelah mendapatkan terapi musik pada kelompok intervensi bermakna dibandingkan kelompok kontrol. Kesimpulannya, terapi musik secara signifikan dapat menurunkan mual muntah lambat akibat kemoterapi. Disarankan agar terapi musik dapat diterapkan sebagai intervensi keperawatan dalam menangani pasien yang mengalami mual muntah lambat akibat kemoterapi.

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Music therapy is one of complementary theray on children who experience delayed nause vomiting as chemotherapy effect. Nausea vomiting is an effect that cause stress in children and their family. The purpose iof this research was to identify the effect of music therapy on delayed nausea vomiting in school age who suffered from cancer. Design research used a quasi experimental with pre-post test control design.Result show that there were significant decrease of average delayed nausea vomiting on intervention group that was given music therapy comparing to control group. Music therapy significantly decrease delayed nause vomiting as chemotherapy effect in school age who suffered from cancer. It is suggested that music therapy can be intergrated as part of nursing intervention in delivering nursing care for patients who experience delayed nausea vomiting as chemotherapy effect."

"Terapi antibiotika empirik telah mengurangi angka kematian secara dramatis dalam penanganan febrile neutropenia, dan inisiasi yang cepat dari terapi antibiotika spektrum luas pada onset demam telah menjadi standar baku. Penelitian ini bertujuan untuk memberikan gambaran penggunaan antibiotika empirik terhadap pasien keganasan darah yang mengalami febrile neutropenia setelah menerima kemoterapi agresif yang meliputi pola penggunaan antibiotika empirik, kesesuaian dengan pola kuman di ruangan, kesesuaian dengan pedoman yang berlaku, tingkat kesembuhan infeksi, serta faktor-faktor yang mempengaruhi tingkat kesembuhan infeksi. Penelitian dilakukan dengan rancangan studi observasional menggunakan desain cross sectional (potong lintang). Pengambilan data dilakukan secara retrospektif terhadap data sekunder yang berupa data rekam medis pasien yang mengalami febrile neutropenia pada populasi terbatas di Ruang Isolasi Imunitas Menurun RS Kanker Dharmais selama periode Agustus 2009-April 2011. Pengolahan data dilakukan secara deskriptif analitik. Selama penelitian terdapat 32 episode febrile neutropenia yang memenuhi kriteria inklusi penelitian. Antibiotika empirik yang banyak digunakan adalah golongan β-laktam dengan penggunaan terbanyak adalah sulferazon dan meropenem, masing-masing sebesar 15,6%, diikuti dengan ceftazidime (12,5%), cefotaxime (12,5%), cefpirom (6,2%) dan tazobactam-peperacillin (6,2%). Sebanyak 27 pasien (84.4%) mendapatkan terapi antibiotika empirik sesuai dengan pedoman yang berlaku dan hanya 15 pasien (46.9%) mendapatkan antibiotika empirik sesuai dengan pola resistensi antimikroba. Faktor-faktor yang berpengaruh signifikan terhadap tingkat kesembuhan infeksi adalah durasi febrile neutropenia (p=0.008), jenis kelamin (p=0.022) dan tingkat resiko neutropenia (p=0.013). Tingkat keberhasilan terapi empirik pada penelitian ini adalah cukup tinggi (68.8%). Penggunaan antibiotika monoterapi meropenem pada penelitian ini memberikan respon klinis dan mikrobiologis yang baik terhadap tingkat kesembuhan infeksi.

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Empirical antibiotic therapy has reduced death rates dramatically in the treatment of febrile neutropenia, and early initiation of broad-spectrum antibiotic therapy at the onset of fever has become the gold standard. This study aims to provide an overview of empirical antibiotics use in patients with blood malignancies who experienced febrile neutropenia after receiving aggressive chemotherapy which includes aspects of empirical antibiotic usage patterns, compliance with the microbiological patterns locally, compliance with current guidelines, clinical outcomes of infection, as well as the factors that affect the clinical outcomes of infection. This study was conducted with the design of an observational study using crosssectional design. Data is collected in a retrospective review of secondary data in the form of medical records of patients who experienced febrile neutropenia in limited populations in the Declines Immunity Isolation Room Dharmais Cancer Hospital during the period August 2009-April 2011. Data processing is done in a descriptive analytic. During this study there were 32 episodes of febrile neutropenia which fulfilled the study inclusion criteria. Empirical antibiotics are widely used β-lactam group with the highest usage is sulferazon and meropenem, respectively of 15.6%, followed by ceftazidime (12.5%), cefotaxime (12.5%), cefpirom (6.2%) and the tazobactam-peperacillin (6.2 %). A total of 27 patients (84.4%) received empirical antibiotic therapy in accordance with current guidelines and only 15 patients (46.9%) received empiric antibiotics according to antimicrobial resistance patterns. The duration of febrile neutropenia (p = 0.008), sex (p = 0.022) and the risk level of neutropenia (p = 0.013) are the significant factors that influence the clinical outcome of infection. The success rate of empirical therapy in this study was as high as 68.8%. Monotherapy antibiotics with meropenem in this study provide a good clinical and microbiological response both to the clinical outcomes of infection."

"ABSTRAKBACKGROUND: The incidence lung tumors and mediastinum tumors are the main causes of death due to malignancies with 12,9% of all malignancy cases. Lung tumors are more common in developing countries. Biopsy of lung tumors and mediastinal tumors is a frequent and multidisciplinary action. The minimally invasive technique that is mostly done is percutaneus transthoracic needle aspiration biopsy (PTNAB). Research states that PTNAB is a safe, effective, and accurate procedure.OBJECTIVE: This study aimed to assess the effect of needle biopsy size on the success of biopsy and the incidence of pneumothorax in intrathoracal tumor patients in Hasan Sadikin General Hospital for the period 2014-2016.METHODS: This study is a clinical epidemiological study and observational analytic with a cross sectional study design involving 232 data of patients who met the inclusion criteria and did not meet the exclusion criteria. Matching is done because there are differences in the number of research subjects in each group. The total number of research subjects is 158 patient data. The test used is chi square.RESULTS: The results showed that PTNABs actions using large and small needles had a success rate of 73,4% and 49,4%, respectively, and were significantly different (p <0,05). The success rate of PTNABs actions is not significantly different from lung tumors and mediastinum. The success rate of PTNABs actions in mediastinal tumors using large and small needles was 92,3% and 50%, respectively, and was significantly different (p <0,05). The incidence of pneumothorax after PTNABs action is zero in both groups so analysis cannot be performed.CONCLUSION: This study concluded that the success of PTNABs actions using large-sized needles on small-sized needles differed significantly."