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Isna Aulia Fajarini
"Obesity is a common comorbidity of type-2 diabetes and one of the most modifiable risk factors for preventing other comorbid conditions, such as diabeticnephropathy and cardiovascular disease. Using a cross-sectional design, this study aimed to determine eating behavior, factors related with obesity and thedominant factor of obesity in patients with type-2 diabetes. Data were collected from 133 members of the Chronic Disease Countermeasure Program inJatinegara Primary Health Care, East Jakarta, that were selected using purposive sampling. Food intake was assessed by 1 × 24-hour food recall and theFood Frequency Questionnaire, Physical activity was assessed by the Global Physical Activity Questionnaire. Results showed that 63.9% of the surveyedtype-2 diabetics were obese (body mass index ≥ 25 kg/m2) and that the respondents consumed more fat than the recommended value (30.77% ± 9.06%)but less energy than the required value (62.06% ± 23.67%). The prevalence of obesity among adults with type-2 diabetes could be associated with nutritional knowledge, education level, and the length of suffering from the disease. Nutritional knowledge was found to be a dominant factor associated with obesity."
Depok: Universitas Indonesia, 2019
613 KESMAS 13:4 (2019)
Artikel Jurnal  Universitas Indonesia Library
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Imam Subekti
"Background: thyroid dysfunction is more likely to occur in diabetes mellitus patients than general population. Until now, no study has been done to find prevalence of hypothyroidism and hyperthyroidism in Indonesian diabetics. This study aimed to find the proportion and characteristics of thyroid dysfunction in Indonesian type 2 diabetes mellitus patients.
Methods: a cross-sectional study was conducted in Endocrine and Diabetes Polyclinic, Department of Internal Medicine, Cipto Mangunkusumo Hospital from July to September 2015. This study include type 2 diabetes mellitus patients, age ≥ 18 year-old, willing to undergo thyroid laboratory testing. In this study, hypothyroidism defined as TSH more than 4.0 mIU/L, while hyperthyroidism is defined as TSH less than 0.4 mIU/L with eCLIA.
Results: from 364 subjects who were recruited from Endocrine and Diabetes Polyclinic, Cipto Mangunkusumo Hospital, 303 subjects underwent this study until analysis. Two hundred and three (273) subjects (90.1%) were euthyroid, 7 subjects (2.31%) were hyperthyroid, and 23 subjects (7.59%) were hypothyroid. Majority of the patients had subclinical hypothyroidism (56.5% based on Zulewski and Billewicz Score and 65.2% based on fT4 laboratory result), while 42.9% and 71.4% subjects had clinical hyperthyroidism based on clinical appearance and fT4 laboratory result respectively.
Conclusion: proportion of hypothyroidism was 7.59% and hyperthyroidism was 2.31%, while the proportion of total thyroid dysfunction was 9.9% among diabetics. It is suggested that screening for thyroid dyscfunction can be done in high risk condition as a part of comprehensive management in type 2 diabetes mellitus patients.

Latar belakang: disfungsi tiroid lebih banyak terjadi pada pasien diabetes dibandingkan populasi umum. Sampai saat ini belum ada penelitian yang menemukan prevalensi hipotiroidisme dan hipertiroidisme pada pasien diabetes mellitus di Indonesia. Tujuan penelitian ini adalah menemukan proporsi dan karakteristik disfungsi tiroid pada pasien diabetes melitus tipe 2 di Indonesia.
Metode: penelitian potong lintang dilakukan di Poliklinik Endokrin dan Diabetes Departemen Ilmu Penyakit Dalam Rumah Sakit Cipto Mangunkusumo pada bulan Juli hingga September 2015. Penelitian ini mengikutsertakan pasien diabetes melitus tipe 2, usia di atas 18 tahun, dan bersedia melakukan pemeriksaan laboratorium fungsi tiroid. Dalam penelitian ini, hipotiroidisme didefinisikan TSH lebih dari 4,0 mIU/L, sementara hipertiroidisme didefinisikan TSH kurang dari 0,4 mIU/L menggunakan metode eCLIA. Hasil: dari 364 subjek yang direkrut di Poliklinik Endokrin dan Diabetes Rumah Sakit Cipto Mangunkusumo, sebanyak 303 subjek mengikuti penelitian hingga analisis. Dua ratus tujuh puluh tiga (273) (90,1%) subjek eutiroidisme, 7 (2,31%) subjek hipertiroidisme, dan 23 (7,59%) subjek hipotiroidisme. Sebagian besar subjek termasuk hipotiroidisme subklinis (56,5% berdasarkan Index Zulewski dan Billewicz, 65,2% berdasarkan pemeriksaan fT4), sementara 42,9% dan 71,4% subjek termasuk kategori hipertiroidisme klinis masing-masing berdasarkan tampilan klinis dan pemeriksaan fT4.
Kesimpulan: pada pasien diabetes melitus tipe 2, proporsi hipotiroidisme adalah 7.59% dan proporsi hipertiroidisme adalah 2.31% sehingga secara total, disfungsi tiroid memiliki proporsi sebesar 9.9%. Disarankan skrining fungsi tiroid dilakukan pada pasien risiko tinggi sebagai manajemen komprehensif pasien diabetes melitus tipe 2
"
Jakarta: Interna Publishing, 2017
610 UI-IJIM 49:4 (2017)
Artikel Jurnal  Universitas Indonesia Library
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Kwan Francesca Gunawan
"ABSTRAK
Diabetes melitus DM merupakan suatu epidemik global. Obesitas merupakan faktor risiko tersering pada terjadinya DM tipe 2. Salah satu komplikasi yang sering dialami oleh penderita DM ialah kaki diabetik. Pada pasien DM dengan obesitas dan kaki diabetik, terapi medik gizi penting untuk mencapai target berat badan, menjaga kadar glikemik, serta mencegah komplikasi DM. Selain itu pemberian nutrisi yang adekuat juga penting untuk mendukung penyembuhan luka. Pasien pada serial kasus ini berusia antara 41 ndash;59 tahun dengan dengan proporsi yang sama antara laki-laki dan perempuan. Keempat pasien memiliki status gizi obes dengan IMT sebesar 26-54,4 kg/m2. Awitan DM pada keempat pasien diketahui bervariasi antara 1-13 tahun. Terapi medik gizi diberikan sesuai dengan klinis, hasil laboratorium, dan asupan terakhir masing-masing pasien. Dari hasil pemantauan didapatkan bahwa dengan terapi nutrisi yang diberikan terjadi penurunan berat badan sebesar 3,2-4,8 kg 3,2-5,8 dan penurunan nilai HbA1c sebanyak 0,3-0,7. Selain itu juga didapatkan ukuran luka yang mengecil dan gejala neuropati berkurang. Pada pasien DM tipe 2 dengan obesitas dan kaki diabetik, terapi medik gizi yang adekuat berkaitan dengan penurunan berat badan, perbaikan kontrol glikemik, dan penyembuhan luka yang baik.

ABSTRACT<>br>
Diabetes mellitus is now a global epidemic. Obesity is a common risk factor in the occurrence of type 2 diabetes. One of the complications that are often experienced by people with diabetes is diabetic foot. In diabetic patients with obesity and diabetic foot, medical nutrition therapy is important to achieve targeted body weight, maintain glycemic levels, and prevent diabetes complications. Good nutrition is also essential for wound healing. This case series consists of four patients who are between 41-59 years old and obese with BMI of 26-54.4 kg/m2. The onset of DM in all four patients is known to vary between 1-13 years. Nutritional therapy is given in accordance with the clinical, laboratory outcomes, and patients' daily intake. It was found that medical nutrition therapy can lead to weight loss of 3.2-4.8 kg (3.2-5.8%) and decreased HbA1c by 0.3-0.7%. It was also observed that the wound size and neuropathy symptoms are reduced. Adequate medical nutrition therapy in type 2 DM patients with obesity and diabetic foot is associated with weight loss, improved glycemic control, and good wound healing."
Depok: Fakultas Kedokteran Universitas Indonesia, 2017
SP-Pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Benedicta M. Suwita
"Multidiscipline care is defined as a care consisting of at least a physician, a nurse, and other healthcare worker (eg. dietician). Multidiscipline care has generated benefits, both in medical aspects (eg. increasing patients compliance) and nonmedical aspects (eg. more cost-effective than conventional treatment). There are several models of multidiscpline care; however, which model is more suitable for type 2 diabetes care is not clear yet. In this review, we aimed to identify and compare multidiscipline care method for reducing glycated hemoglobin ( HbA1C) levels in type 2 diabetes patients, particularly Asian patients because they have greater tendency to develop type 2 diabetes at lower degrees of obesity and at younger ages than Caucasian ethnic group. There were limited number of studies examining multidiscipline care for type 2 diabetes patients, moreover for Asian patients. They showed mixed results on the efficacy of multidiscipline care in achieving HbA1C target. Healthcare personnel visit, either personal or group session, appeared effective both for general and Asian T2DM patients. It needs further studies to clarify which models are most effective for practices of varying cultures, socio-economic condition, and healthcare settings.

Tatalaksana multidisiplin didefinisikan sebagai tatalaksana yang melibatkan setidaknya satu dokter, satu perawat, dan petugas kesehatan lainnya (contohnya dietisien). Tatalaksana multidisiplin dapat memberikan keuntungan, baik dalam aspek medis (misalnya meningkatkan kepatuhan berobat pasien) dan non-medis (misalnya meningkatkan efektivitas biaya dibandingkan tatalaksana konservatif). Terdapat beberapa model tatalaksana multidisiplin; namun demikian, model yang paling cocok untuk tatalaksana diabetes mellitus tipe 2 belum jelas. Dalam kajian ini, penulis bertujuan mengidentifikasi dan membandingkan berbagai jenis tatalaksana multidisiplin dalam menurunkan kadar hemoglobin glikosilasi (HbA1C) pada pasien diabetes mellitus tipe 2, terutama pasien ras Asia, karena golongan ini memiliki kecenderungan untuk mengidap diabetes mellitus tipe 2 pada derajat obesitas yang lebih rendah dan usia yang lebih muda dibandingkan kelompok ras Kaukasia. Penelitian mengenai tatalaksana multidisiplin pada pasien diabetes mellitus tipe 2 masih terbatas, terlebih untuk pasien ras Asia. Studi-studi tersebut menunjukkan hasil yang bervariasi mengenai efektivitas tatalaksana multidisiplin untuk mencapai target HbA1C. Kunjungan tenaga medis, baik dalam sesi perorangan ataupun kelompok, tampak efektif pada populasi pasien diabetes mellitus tipe 2 secara umum dan pada ras Asia. Penelitian lebih lanjut masih diperlukan untuk mengetahui model tatalaksana multidisiplin mana yang paling cocok untuk pasien di wilayah tertentu dengan kebudayaan, kondisi sosial ekonomi dan fasilitas kesehatan yang beragam"
Jakarta: University of Indonesia. Faculty of Medicine, 2017
610 UI-IJIM 49:3 (2017)
Artikel Jurnal  Universitas Indonesia Library
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Luthfi Nabilah Qonitah
"Diabetes melitus (DM) tipe 2 merupakan suatu penyakit yang ditandai dengan kondisi kadar glukosa darah yang tinggi karena ketidakmampuan tubuh untuk menggunakan insulin secara normal atau untuk memproduksi insulin yang cukup. Dalam kurun waktu 5 tahun, prevalensi diabetes melitus pada penduduk berusia ≥ 15 tahun meningkat dari 6,9% pada tahun 2013 menjadi 8,5% pada tahun 2018. Penelitian ini bertujuan untuk mengetahui pengaruh obesitas terhadap DM tipe 2 di Indonesia, dengan desain penelitian kohort retrospektif. Data yang digunakan berasal dari IFLS-1 dan IFLS-5 dengan sampel sebesar 4.707 dan dianalisis menggunakan uji cox regression. Hasil penelitian ini menunjukkan terdapat 7,4% sampel mengalami diabetes tipe 2. Hasil analisis bivariat menunjukkan terdapat pengaruh obesitas dan umur pada tahun 1993 terhadap kejadian DM tipe 2 tahun 2014; dan terdapat hubungan antara konsumsi fast food, konsumsi soft drink, konsumsi buah, aktivitas fisik, dan wilayah tempat tinggal pada tahun 2014 dengan DM tipe 2. Sedangkan, konsumsi cemilan gorengan, konsumsi cemilan manis, konsumsi sayur dan status gizi pada tahun 2014, kebiasaan merokok pada tahun 1993, tidak berhubungan yang bermakna dengan DM tipe 2. Kesimpulan dari penelitian ini adalah status gizi obesitas berisiko 5,62 kali terkena DM tipe 2 dibandingkan dengan status gizi normal setelah dikontrol oleh variabel usia, status gizi tahun 2014, dan wilayah tempat tinggal sebagai confounding

Type 2 diabetes mellitus (DM) is a disease characterized by high blood glucose levels due to the body's inability to use insulin normally or to produce enough insulin. Within 5 years, the prevalence of diabetes mellitus in the population aged 15 years and above increased from 6.9% in 2013 to 8.5% in 2018. This study aims to determine the effect of obesity on type 2 DM in Indonesia, with a research design retrospective cohort. The data used comes from IFLS-1 and IFLS-5 with a sample of 4,707 and analyzed using cox regression test. The results of this study showed that 7.4% of the sample had type 2 diabetes. The results of the bivariate analysis showed that there was an effect of obesity and age in 1993 on the incidence of type 2 diabetes in 2014; and there is a relationship between consumption of fast food, consumption of soft drinks, consumption of fruit, physical activity, and area of ​​residence in 2014 with type 2 DM. Meanwhile, consumption of fried snacks, consumption of sweet snacks, consumption of vegetables and nutritional status in 2014, habits smoking in 1993, was not significantly associated with type 2 diabetes. The conclusion of this study is that the nutritional status of obesity has a 5.62 times risk of developing type 2 diabetes compared to normal nutritional status after controlling for variables of age, nutritional status in 2014, and the area of residence as confounding."
Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2022
S-pdf
UI - Skripsi Membership  Universitas Indonesia Library
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Novanza Rayhan Natasaputra
"Latar belakang: Diabetes melitus tipe 2 (DMT2) disandang oleh 10,7 juta orang di Indonesia dan menjadi tiga besar penyakit tidak menular penyebab kematian. Sebagian besar kematian terjadi akibat komplikasi yang diawali oleh kontrol glikemik kadar HbA1c yang tidak adekuat, dan diasosiasikan dengan aspek multifaktorial seperti karakteristik sosiodemografi maupun perilaku individu dalam merawat diri—Self-Care Behaviour. Penelitian ini bertujuan mengetahui hubungan antara tingkat kontrol glikemik pada penyandang DMT2 dengan karakteristik sosiodemografi dan perilaku self-care yang dimiliki. Metode: Studi ini menggunakan desain potong-lintang terhadap data sekunder yang dikumpulkan sebelumnya pada Kohor Penyakit Tidak Menular Bogor 2021. Data dikumpulkan menggunakan kuesioner Self-Care Behaviour yang divalidasi dalam bahasa Indonesia, pengukuran kadar HbA1c serta karakteristik penyandang. Populasi studi adalah penyandang DMT2 di lima fasilitas kesehatan primer di Kota Bogor. Sampel dianalisis menggunakan uji Chi-Square dan perhitungan odds ratio. Hasil: Analisis dilakukan pada 237 responden, terdiri atas 90 responden kelompok usia lansia (38%) dan 147 dewasa (62%). Jenis kelamin responden didominasi perempuan sebanyak 171 responden (72,2%) dan 66 responden laki-laki (27,8%). Sebanyak 149 responden (62,9%) memiliki skor Self-Care Behaviour yang baik. Sejumlah 134 responden (56,6%) memiliki kadar HbA1c yang terkontrol. Empat dari tujuh komponen Self-Care Behaviour—pengetahuan, motivasi, dukungan, dan efikasi—berhubungan dengan kontrol glikemik (p<0,001). Efikasi menjadi prediktor kadar HbA1c terkontrol paling kuat (Odds ratio [OR]: 9,7; 95% Confidence Interval [CI] 5,27–17,67). Skor keseluruhan Self-Care Behaviour yang baik meningkatkan probabilitas kadar HbA1c terkontrol 9,1 kali (95% CI 4,94–16,7) dibanding skor kurang baik. Komponen komunikasi, sikap, dan pembiayaan tidak memiliki hubungan signifikan. Tingkat pendidikan dan riwayat DMT2 di keluarga berhubungan dengan tingkat keseluruhan Self-Care Behaviour dan dengan kontrol kadar HbA1c. Kesimpulan: Aspek perilaku self-care pada penyandang DMT2 mempunyai dampak substansial dan signifikan terhadap kontrol glikemik yang dimiliki penyandang.

Introduction: Type 2 diabetes mellitus (T2DM) affects 10.7 million individuals in Indonesia and ranks among the top three non-communicable diseases leading to death. Most of mortality result from complications initiated by inadequate glycemic control, associated with multifactorial aspects such as sociodemographic characteristics and individual self-care behaviour. This study aims to explore the relationship between glycemic control levels in individuals with T2DM and their sociodemographic characteristics and self-care behavior. Method: This study is a cross-sectional study utilizing previously collected secondary data from the Non-Communicable Disease Cohort in Bogor 2021 Data were collected using a validated Self-Care Behaviour questionnaire in Bahasa Indonesia, along with primary data of HbA1c levels and respondent socio-characteristics. The study population consisted of individuals with T2DM from five primary healthcare facilities in Bogor city. The samples were analyzed using Chi-Square test and risk calculation. Result: The research analysis included 237 respondents, consisting of 90 elderly (38%) and 147 adults respondents (62%). The respondents were predominantly female, with 171 respondents (72.2%) compared to 66 male respondants (27.8%). A total of 149 respondents (62.9%) exhibited good Self-Care Behaviour scores. Approximately 134 respondents (56.6%) maintained controlled HbA1c levels. Four out of seven Self-Care Behaviour components—knowledge, motivation, support, and efficacy—were associated with glycemic control (p<0.001). Efficacy identified as the most influential predictor for controlled HbA1c levels (odds ratio [OR]: 9.7, 95% Confidence Interval [CI] 5.27–17.67). An overall good Self-Care Behaviour score is associated with a 9.1-fold increased probability of achieving controlled HbA1c levels (95% CI 4.94–16.7) compared to group with poor score. Self-Care Behaviour components of communication, attitude, and financing were not signicifantly associated. Education level and a family history of T2DM were associated with overall Self-Care Behaviour and with HbA1c control."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
S-pdf
UI - Skripsi Membership  Universitas Indonesia Library
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Johanda Damanik
"Type 2 diabetes mellitus (T2DM) is strongly associated with lower performance on multiple domains of cognitive function and with structural abnormalities of the brain. With the growing epidemic of diabetes and aging population, neural complications of diabetes are expected to rise and becoming a challenge for future health implications. Understanding pathophysiology, factors associated with this complication, manifestation of cognitive impairment and various metabolic and neuroradiologic markers suggestive of this pathologic condition is crucial for proper management of this potentially debilitating complication of T2DM. This review will discuss briefly important aspects of cognitive impairment in T2DM."
Jakarta: University of Indonesia. Faculty of Medicine, 2021
610 UI-IJIM 53:2 (2021)
Artikel Jurnal  Universitas Indonesia Library
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LeRoith, Derek
"Prevention of type 2 diabetes can be achieved properly by simultaneous prevention of obesity. Prediabetes, or metabolic syndrome, is the period between simple obesity and diabetes, and this critical period needs to be identified in a more consistent and systematic manner by clinicians worldwide. Clinical trials have indicated that diabetes prevention can be achieved by lifestyle changes and also by certain medications, though none are yet approved for use in prevention. On the other hand, there are funding agencies such as the NIH, CDC, and state institutions that are interested in studying the prevention paradigms in different communities and ethnic minorities who are most prone to this epidemic. For these reasons, this title by renowned physician-scientist Derek LeRoith is both timely and vitally important for academic physicians, practitioners, allied health care providers, analysts, community activists, and all others interested in this increasing epidemic. This book provides a unique and comprehensive synthesis of the prevention and early diagnosis of Type 2 Diabetes, focusing on identifying risk factors and then moving into topics that address how to prevent their progression to full-blown diabetes. The difficult task of changing patients’ behavior is given special emphasis. The chapters in this practical volume are written by a wide range of international experts, reflecting the editor’s distinguished, internationally renowned career. The volume is organized in eight sections: an introduction to the overall issue of prevention, definitions of values based on ADA guidelines, pathophysiology, discussion of a range of interventional trials regarding prevention, and an overview of state-of-the-art clinical management approaches.
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New York: Springer, 2012
e20426042
eBooks  Universitas Indonesia Library
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"Sialolithiasis is a common disease of the submandibular glands or its duct but rare in parotids of patients, especially in male adults. The accessory of salivary glands are small, unsheathed masses with a small canaliculi. The irritant factors might be due to inflammation of the inner layer of the canaliculi, that often concomitant to saliva stasis. This process leads to development of calculus that it is related to secretive specificity of the submandibular gland. The essential factor for its calcification is the stagnation of secretory material rich in calcium. The accumulation of this material would cause swelling, further obstruction and atrophy until there is widespread inflammation that has been termed sialadenitis. Diabetes mellitus is one of the medically compromised diseases. Although there are many associations between diabetes mellitus and oral health, lack of investigation in this area has been done to study salivary gland alterations. Many diabetic patient complained xerostomia, a decreasing salivary flow and enlargement if the parotid gland due to a compensatory mechanism to xerostomia that has been termed sialadenosis. This review article summarized that there is no relationship between sialolithiasis and poorly controlled type 2 diabetes mellitus. "
[Fakultas Kedokteran Gigi Universitas Indonesia, Journal of Dentistry Indonesia], 2007
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Artikel Jurnal  Universitas Indonesia Library
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Natasya Setyamarta
"ABSTRAK
Diabetes mellitus tipe 2 DM tipe 2 merupakan penyakit kronis yang membutuhkan perawatan berkelanjutan seumur hidup untuk mencegah komplikasi akut dan kronik. Manajemen perawatan diri merupakan aspek dasar dari perawatan diabetes. Salah satu faktor yang dapat meningkatkan perilaku perawatan diri yaitu dukungan sosial yang diperoleh dari keluarga, tenaga kesehatan, teman, atau sesama pasien diabetes. Penelitian ini bertujuan untuk mengetahui gambaran perilaku perawatan diri pasien DM tipe 2 di Persadia Depok. Penelitian kuantitatif deskriptif ini menggunakan desain cross-sectional, melibatkan 52 responden pasien DM tipe 2 yang begabung di Persadia kota Depok. Instrumen yang digunakan untuk mengukur perilaku perawatan diri yaitu kuesioner The Summary of Diabetes Self-Care Activities. Hasil penelitian menunjukkan bahwa aktivitas perawatan diri responden dalam satu minggu terakhir adalah 4,4 hari Median 4,4; Minimal-Maksimal 2,6-5,4; 95 CI 4,1-4,5 , dan hanya setengah 50 responden yang memiliki perilaku perawatan diri kategori baik. Perilaku yang sudah baik yaitu diet, latihan fisik, dan kepatuhan medikasi, sedangkan perilaku yang masih buruk yaitu pemantauan glukosa darah mandiri dan perawatan kaki. Penelitian ini merekomendasikan agar perawat dan tenaga kesehatan lainnya meningkatkan edukasi dan dukungan terkait perilaku perawatan diri pasien diabetes, terutama pemantauan glukosa darah dan perawatan kaki.

ABSTRACT
Type 2 diabetes mellitus type 2 DM is a chronic disease that requires long term management throughout the life to prevent acute and chronic complications. Self care is a fundamental and integral part of diabetes management. Social support obtained from family, health professional, friends, or diabetic peers may predict good self care behaviour. The purpose of this study is to evaluate the self care behaviour of adult with type 2 DM in Persadia Depok. This quantitative study used a cross sectional design. A consecutive sample of 52 subjects with type 2 DM who joined in Persadia Depok was included. The instrument used to measure self care behaviour is The Summary of Diabetes Self Care Activities questionnaire. The results showed that self care behaviour of participants in the last seven days is 4,4 days Median 4.4, Minimal Maximum 2.6 5.4, 95 CI 4.1 4.5 . Self care was described as ldquo good rdquo in only half of the participant 50 . Self care behaviour was reported good in diet, physical exercise, and taking medication, but it was poor in self monitoring of blood glucose SMBG and foot care. This study recommends that nurses and other health professionals should promote education and support to improve patients self care behaviour, especially SMBG and foot care."
2017
S67620
UI - Skripsi Membership  Universitas Indonesia Library
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