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"ABSTRAKLatar Belakang: Keguguran berulang memiliki dampak psikologis yang besar, didefinisikan sebagai keguguran dua kali atau lebih. Sekitar 10-15% dari semua kehamilan yang secara klinis berakhir dengan keguguran. Sekitar 2% wanita mengalami dua kali keguguran dan 0,4-1% wanita mengalami tiga kali secara berturut-turut. Prevalensi dan variasi data di setiap negara berbeda. Penelitian ini bertujuan untuk mendeskripsikan pola karakteristik subjek di poliklinik kebidanan Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo. Metode : Data dikumpulkan selama 5 tahun dari 2013 hingga 2017. Peserta adalah pasien dengan riwayat keguguran berulang yang tercatat di poliklinik Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo kemudian data dianalisis secara statistik deskriptif. Hasil: Prevalensi keguguran berulang sebesar 28 kasus. Usia termuda yang mengalami keguguran berulang adalah 25 tahun sedangkan usia tertua 46 tahun. 80% kasus merupakan keguguran berulang primer, 20% kasus merupakan keguguran berulang sekunder. Terdapat 30% kasus dengan Indeks massa tubuh normal, 6.67% underweight, 36.67% overweight dan 26.67% dengan obesitas. Pemeriksaan ACA didapatkan 7.1% hanya ACA IgG positif, 14.3% hanya ACA IgM positif, 7.1% ACA IgG dan IgM positif dan 71.4% ACA IgG dan IgM negatif. Kesimpulan:. Karakteristik pasien keguguran berulang pada penelitian ini sangat beragam.

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ABSTRACTBackground: Recurrent miscarriage has a large psychological impact, defined as twice or more miscarriages. About 10-15% of all pregnancies that clinically end in miscarriage. About 2% of women experience two miscarriages and 0.4-1% of women experience three times in a row. The prevalence and variation of data in each country is different. This study aims to describe the pattern of subject characteristics in polyclinic of the National Center General Hospital Dr. Cipto Mangunkusumo. Method: Data was collected for 5 years from 2013 to 2017. Participants were patients with a history of recurrent miscarriages recorded in the polyclinic of the National Center General Hospital Cipto Mangunkusumo then the data were analyzed descriptively. Results: The prevalence of recurrent miscarriages was 28 cases. The youngest age to experience a recurrent miscarriage is 25 years while the oldest age is 46 years. 80% of cases are primary recurrent miscarriages, 20% of cases are secondary recurrent miscarriages. There are 30% of cases with a normal body mass index, 6.67% underweight, 36.67% overweight and 26.67% with obesity. ACA examination found 7.1% only ACA IgG positive, 14.3% only ACA IgM positive, 7.1% ACA IgG and IgM positive and 71.4% ACA IgG and IgM negative. Conclusion:. The characteristics of recurrent miscarriage patients in this study are very diverse."

"Gangguan depresi merupakan salah satu gangguan jiwa terbanyak yang meningkatkan angka morbiditas dan mortalitas penderitanya. Gangguan ini sebenarnya bisa diberikan tatalaksana berupa farmakologis dan non farmakologis, salah satunya adalah psikoterapi. Sayangnya, banyak pasien yang menderita gangguan ini tidak mendapatkan layanan ini secara adekuat. Pasien-pasien yang sudah mendapatkan psikoterapi pun ternyata banyak yang tidak patuh terhadap psikoterapi. Hal ini tentunya memengaruhi luaran dari psikoterapi tersebut. Fenomena ini tentunya dipengaruhi oleh berbagai macam faktor. Namun, masih sangat sedikit penelitian mengenai faktor-faktor yang memengaruhi kepatuhan psikoterapi ini, khususnya di Indonesia. Oleh karena itu, penelitian ini dilakukan untuk mengetahui faktor-faktor yang memengaruhi kepatuhan psikoterapi pada pasien dengan gangguan depresi, khususnya di Poli Jiwa Dewasa (PJD) RSCM.Penelitian dilakukan dengan desain potong lintang dari Desember 2022 hingga Desember 2023. Sampel penelitian adalah pasien dewasa dengan gangguan depresi yang mendapatkan psikoterapi di PJD RSCM. Sebanyak 82 subjek penelitian terpilih berdasarkan metode purposive sampling. Data diambil dengan menggunakan beberapa kuesioner serta data rekam medis pasien. Analisis data digunakan dengan SPSS untuk melihat karakteristik dasar subjek yang diteliti, analisis bivariat hingga multivariat dari berbagai faktor yang diteliti dengan kepatuhan psikoterapi.Hasil penelitian menunjukkan bahwa proporsi kepatuhan psikoterapi sebesar 0,73 (CI95% = 0,62 – 0,82). Dari 82 orang subjek yang diteliti, mayoritas adalah perempuan (84,1%) dengan pendidikan tinggi (63,4%) dan status ekonomi menengah (72,0%). Hasil analisis bivariat menunjukkan hubungan yang signifikan secara statistik antara stigma dan konsistensi terapis (p<0,05). Lebih lanjut lagi, stigma yang rendah dan terapis yang tetap memiliki subjek yang patuh pada psikoterapi lebih banyak dibandingkan dengan stigma yang tinggi dan terapis yang tidak tetap. Dari analisis multivariat, didapatkan faktor yang paling memengaruhi kepatuhan psikoterapi adalah konsistensi terapis (p=0,045).

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Depressive disorders are one of the most common mental disorders that increase the morbidity and mortality rates of its sufferers. This disorder can actually be treated by pharmacological and non-pharmacological approach, one of which is psychotherapy. Unfortunately, many patients who suffer from this disorder do not receive adequate services. It turns out that many patients who have received psychotherapy are not compliant with psychotherapy. This condition will affect the outcome of psychotherapy. This phenomenon is influenced by various factors. However, research regarding the factors that influence psychotherapy adherence is currently scarce, especially in Indonesia. Therefore, this research was conducted to determine the factors that influence psychotherapy compliance in patients with depressive disorders, especially at the Adult Psychiatric Polyclinic RSCM.

The research was conducted with a cross-sectional design from December 2022 to December 2023. The research sample was adult patients with depressive disorders who received psychotherapy at Adult Psychiatric Polyclinic RSCM. A total of 82 research subjects were selected based on the purposive sampling method. Data was taken using several questionnaires and patient medical record. Data analysis was used with SPSS to look at the basic characteristics of the subjects studied, bivariate to multivariate analysis of various factors studied and psychotherapy compliance.

The results showed that the proportion of psychotherapy compliance was 0.73 (CI95% = 0.62 – 0.82). Of the 82 subjects studied, the majority were women (84.1%) with higher education (63.4%) and middle economic status (72.0%). The results of bivariate analysis showed a statistically significant relationship between stigma and therapist consistency (p<0.05). Furthermore, low stigma and permanent therapists had more subjects who adhered to psychotherapy compared to high stigma and non-permanent therapists. From multivariate analysis, it was found that the factor that most influenced psychotherapy compliance was therapist consistency (p=0.045)."

"ABSTRAKTesis ini membahas Rencana Strategis Unit Pelayanan Terpadu RSCM Kencana RSUPN Dr. Cipto Mangunkusumo Tahun 2013 – 2017. Penelitian ini menggunakan metode kualitatif dengan pendekatan operation research. Tehnik yang digunakan adalah wawancara mendalam dan Consensus Decision Making Group (CDMG). Hasil Penelitian ini adalah terbentuknya visi dan misi serta diketahuinya aspek internal dan eksternal yang mempengaruhi RSCM Kencana. Aspek internal (kekuatan dan kelemahan) dan aspek eksternal (peluang dan ancaman) yang mempengaruhi RSCM Kencana. Hasil penelitian menghasilkan analisa SWOT RSCM Kencana ada di kuadran tiga dengan strategi Turn Around, Matriks TOWS ada di internal fix it dan analisa dengan matriks IE RSCM Kencana ada di kuadran III, V dan VII yaitu Hold and Maintenance. Dimana alternatif strategi dianalisa adalah pengembangan produk. Pengembangan produk yang dipilih sebagai prioritas dari matriks QSPM adalah pembuatan paket layanan.

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ABSTRACTThis thesis discussed Strategic Plan of Integrated Services Unit RSCM Kencana at RSUPN Dr. Cipto Mangunkusumo for 2013-2017. This study used qualitative with the operation research approach. The techniques used were in-depth interviews and Consensus Decision Making Group (CDMG). This study result is the new vision and mission. The result of the research discussed internal aspects (strengths and weaknesses) and external aspects (opportunities and threats) influencing the RSCM Kencana. The results of SWOT analysis in third quadrant with Turn Around strategy, TOWS matrix in internal fix it and IE matrix analysis is at quadrant III, V and VII which strategy used are Hold and Maintenance. Where the alternative strategy is product development. The choice of the priority development products from the QSPM matrix is making the service packet. Keywords: vision, mission and strategic planning."

"Latar BelakangParese nervus abdusen (CN VI) merupakan kondisi kelemahan saraf motorik yang menginervasi musculus rectus lateralis yang berperan dalam mengontrol gerakan abduksi bola mata. Kelainan ini memiliki beragam etiologi dan manifestasi klinis pada sistem penglihatan sedangkan pemberian tata laksana sangat bergantung pada ketepatan seorang klinisi dalam menentukan diagnosis pada pasien. Akibat adanya keterbatasan dalam penelitian sebelumnya, studi ini bertujuan untuk mengetahui karakteristik klinis dan demografis pasien dengan parese CN VI terisolasi secara lebih objektif.Metode Desain penelitian ini adalah deskriptif cross sectional dengan menggunakan data retrospektif dari penelusuran rekam medis pada periode 1 Januari 2022 - 31 Desember 2023.Hasil Terdapat 83 subjek pasien dengan parese CN VI yang terinklusi dalam penelitian ini. Rerata usia pasien adalah 43,2 tahun dengan pola kelainan terbanyak bersifat unilateral pada 69,8% pasien. Sebanyak 43,4% pasien datang dengan keluhan utama penglihatan ganda. Karakteristik klinis terbanyak yang ditemukan adalah hambatan gerak bola mata (92,6%), diplopia (79,5%), dan defek lapang pandang (38,9%). Etiologi parese CN VI yang berhasil ditemukan dalam penelitian ini adalah vaskulopati (n=29, 34,9%), idiopatik (n=26, 31,3%), neoplasma (n=21, 25,3%), trauma (n=4, 4,8%), dan infeksi/inflamasi (n=3, 3,6%). Kesimpulan Rerata usia pasien dengan CN VI terisolasi adalah 43,2 tahun dengan lateralitas terbanyak bersifat unilateral. Karakteristik klinis terbanyak yang ditemukan adalah hambatan gerak bola mata, diplopia, dan defek lapang pandang, sedangkan penurunan tajam penglihatan, abnormalitas fundus, dan proptosis cukup jarang ditemui. Vaskulopati menjadi faktor etiologi parese CN VI yang tersering.

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Abducens nerve palsy is a condition involving weakness of the motor nerve that innervates the lateral rectus muscle, which has the function of controlling the abduction of eye movement. This disorder has a range of etiologies and clinical manifestations within the visual function, while the treatment provided really depends on the clinician's accuracy in diagnosing the patient. Due to limitations in previous research, this study aims to objectively identify the clinical features and demographic of patients with isolated abducens nerve palsy.

Method

The design of this study is descriptive cross-sectional, using retrospective data from medical records from the period of January 1, 2022, to December 31, 2023.

Results

A total of 83 patients were included in this study. The mean age of patients was 43.2 years, with the majority of cases were unilateral (69.8%). A main complaint of diplopia was reported by 43.4% of the patients. The most common clinical features found were restricted eye movement (92.6%), diplopia (79.5%), and visual field defects (38.9%). The identified etiologies of CN VI palsy in this study were vasculopathy (n=29, 34.9%), idiopathic (n=26, 31.3%), neoplasm (n=21, 25.3%), trauma (n=4, 4.8%), and infection/inflammation (n=3, 3.6%).

Conclusion

The mean age of patients with isolated CN VI palsy was 43.2 years, with the majority of cases were unilateral. The most common clinical features observed were restricted eye movement, diplopia, and visual field defects, while reduced visual acuity, fundus abnormalities, and proptosis were relatively rare. Vasculopathy was the most frequent etiological factor for CN VI palsy."

"Latar BelakangParese nervus abdusen (CN VI) merupakan kondisi kelemahan saraf motorik yang menginervasi musculus rectus lateralis yang berperan dalam mengontrol gerakan abduksi bola mata. Kelainan ini memiliki beragam etiologi dan manifestasi klinis pada sistem penglihatan sedangkan pemberian tata laksana sangat bergantung pada ketepatan seorang klinisi dalam menentukan diagnosis pada pasien. Akibat adanya keterbatasan dalam penelitian sebelumnya, studi ini bertujuan untuk mengetahui karakteristik klinis dan demografis pasien dengan parese CN VI terisolasi secara lebih objektif.Metode Desain penelitian ini adalah deskriptif cross sectional dengan menggunakan data retrospektif dari penelusuran rekam medis pada periode 1 Januari 2022 - 31 Desember 2023.Hasil Terdapat 83 subjek pasien dengan parese CN VI yang terinklusi dalam penelitian ini. Rerata usia pasien adalah 43,2 tahun dengan pola kelainan terbanyak bersifat unilateral pada 69,8% pasien. Sebanyak 43,4% pasien datang dengan keluhan utama penglihatan ganda. Karakteristik klinis terbanyak yang ditemukan adalah hambatan gerak bola mata (92,6%), diplopia (79,5%), dan defek lapang pandang (38,9%). Etiologi parese CN VI yang berhasil ditemukan dalam penelitian ini adalah vaskulopati (n=29, 34,9%), idiopatik (n=26, 31,3%), neoplasma (n=21, 25,3%), trauma (n=4, 4,8%), dan infeksi/inflamasi (n=3, 3,6%). Kesimpulan Rerata usia pasien dengan CN VI terisolasi adalah 43,2 tahun dengan lateralitas terbanyak bersifat unilateral. Karakteristik klinis terbanyak yang ditemukan adalah hambatan gerak bola mata, diplopia, dan defek lapang pandang, sedangkan penurunan tajam penglihatan, abnormalitas fundus, dan proptosis cukup jarang ditemui. Vaskulopati menjadi faktor etiologi parese CN VI yang tersering.

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Abducens nerve palsy is a condition involving weakness of the motor nerve that innervates the lateral rectus muscle, which has the function of controlling the abduction of eye movement. This disorder has a range of etiologies and clinical manifestations within the visual function, while the treatment provided really depends on the clinician's accuracy in diagnosing the patient. Due to limitations in previous research, this study aims to objectively identify the clinical features and demographic of patients with isolated abducens nerve palsy.

Method

The design of this study is descriptive cross-sectional, using retrospective data from medical records from the period of January 1, 2022, to December 31, 2023.

Results

A total of 83 patients were included in this study. The mean age of patients was 43.2 years, with the majority of cases were unilateral (69.8%). A main complaint of diplopia was reported by 43.4% of the patients. The most common clinical features found were restricted eye movement (92.6%), diplopia (79.5%), and visual field defects (38.9%). The identified etiologies of CN VI palsy in this study were vasculopathy (n=29, 34.9%), idiopathic (n=26, 31.3%), neoplasm (n=21, 25.3%), trauma (n=4, 4.8%), and infection/inflammation (n=3, 3.6%).

Conclusion

The mean age of patients with isolated CN VI palsy was 43.2 years, with the majority of cases were unilateral. The most common clinical features observed were restricted eye movement, diplopia, and visual field defects, while reduced visual acuity, fundus abnormalities, and proptosis were relatively rare. Vasculopathy was the most frequent etiological factor for CN VI palsy."

"Asupan kebutuhan nutrisi dan obat yang cukup, berperan penting dalam tercapainya kesembuhan pasien. Namun, hal ini seringkali menjadi kendala bagi pasien yang secara fisik mengalami hambatan untuk diberikan asupan secara oral. Salah satu cara yang dapat digunakan oleh tenaga kesehatan di rumah sakit dalam mengatasi kendala ini adalah dengan menggunakan Enteral Feeding Tube (EFT). Salah satu contoh dari EFT sendiri adalah Nasogastric Tube (NGT) dimana selang dimasukkan melalui saluran orofaring posterior dan esofagus untuk tujuan akhir pemberian obat/nutrisi di lambung. Sediaan obat harus melewati tahap preparasi untuk disesuaikan sediaannya agar dapat disalurkan melalui NGT dan tetap dipertahankan karakteristik fisikokimia, biofarmasetik, dan faramkologis obat. Pelayanan Informasi Obat (PIO) merupakan salah satu pelayanan farmasi klinik oleh apoteker yang dapat dilakukan di rumah sakit. PIO dapat disalurkan dalam beberapa jenis, salah satunya adalah pembuatan buku pedoman. RSUPN Dr. Cipto Mangunkusumo membuat buku pedoman daftar obat yang dapat diadministrasikan melalui NGT dalam rangka membantu memberikan informasi terkait jenis dan nama obat yang kompatibel untuk diadministrasikan menggunakan selang NGT. Buku pedoman tersebut terkahir diperbarui pada tahun 2018. Laporan ini menyajikan pembaruan buku pedoman yang memuat informasi terbaru terhadap beberapa obat yang tercantum dalam daftar obat yang digunakan dalam RSUPN Dr. Cipto Mangunkusumo pada tahun 2022 beserta tahapan pemberiannya untuk mencapai keberhasilan pengobatan yang tepat.

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Adequate intake of nutritional and drug needs, plays an important role in achieving patient’s recovery. However, it is often be an obstacle for patients who physically experience difficulties in taking oral medicine. One way that can be used by health workers in hospitals to overcome this problem is to use an Enteral Feeding Tube (EFT). One of the example is Nasogastric Tube (NGT), where a tube is inserted through the posterior oropharynx and esophagus for the ultimate goal of administering drugs/nutrition to the stomach. The drug preparation will go through the preparation stage where it will be adjusted so that it can be channeled through the NGT hence still maintaining the physicochemical, biopharmaceutical and pharmacological characteristics of the drug. Drug Information Service (DIS) is one of the clinical pharmaceutical practice by pharmacists that can be performed in hospitals. DIS can be carried out in several types, including the manufacturing of guidebook. RSUPN Dr. Cipto Mangunkusumo involved in helping to provide information regarding the types and names of drugs that are compatible to be administered via NGT by creating a guidebook for the list of drugs that can be administered through the NGT. The guidebook itself was last updated in 2018. This report presents an updated guidebook that contains the latest information on several drugs from the list of drugs used in RSUPN Dr. Cipto Mangunkusumo in 2022 along with the steps of administration to achieve the success of proper treatment."

"[ABSTRAKPendahuluan : Glioma adalah jenis tumor yang paling umum dari neoplasma intraserebralprimer. Tumor ganas primer sistem saraf pusat (SSP) mencapai sekitar 2% dari semua kankerdan high grade glioma adalah jenis yang paling banyak ditemukan. High grade gliomamenyebabkan tingkat morbiditas dan mortalitas yang tinggi. Saat ini belum ada data yangmenggambarkan profil pasien glioma yang menjalani radioterapi di Indonesia.Metode penelitian : Penelitian ini merupakan penelitian retrospektif deskriptif analitikterhadap 121 pasien glioma yang mendapat radiasi di departemen Radioterapi RSUPN Dr.Cipto mangunkusumo dari Januari 2009 sampai Januari 2014. Data diperoleh dari catatanmedisdan hasil penelusuran melalui telepon terhadap pasien atau keluarganya. Respon tumordianalisa terhadap 22 pasien yang mempunyai CT scan atau MRI pre dan post radiasi denganmenggunakan kriteria RECIST.Hasil : Sebagian besar pasien adalah laki-laki (53,7%), dengan usia rata-rata 45 tahun.Histopatologi yang paling banyak ditemukan adalah astrositoma. Prosedur bedah yang palingbanyak ditemukan pada penelitian ini adalah craniotomi removal tumor (70%). Teknik 3DCRT paling banyak digunakan yaitu pada 77,7% pasien. Nimotuzumab sebagai antibodimonoklonal digunakan pada 9% pasien. Respon parsial ditemukan 59,1%. Analisis kesintasanhidup tiga tahun dari seratus sebelas pasien yang memenuhi kriteria didapatkan angkakesintasan yaitu 46,15%. Analisis kaplan meyer menunjukkan overall treatment timemerupakan faktor prognostik untuk kesintasan hidup (p = 0,016).Kesimpulan : Teknik operasi terbanyak pada pasien glioma yang menjalani radiasi didepartemen radioterapi RSUPN DR. Cipto Mangunkusumo adalah kraniotomi removal tumor(70,9%). Teknik 3D CRT adalah teknik radiasi yang paling banyak digunakan. Responparsial ditemukan 59,1%. Kesintasan hidup tiga tahun pasien glioma yaitu 46,2% dan overalltreatment time merupakan faktor prognostik yang bermakna untuk kesintasan hidup

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ABSTRACTIntroduction : Glioma is the most common type of primary intracerebral neoplasms. Highgrade glioma being the most frekuent type found (70,9%) causes a high morbidity andmortality rate. There is currently no data describing the profile management of patientsundergoing radiotherapy glioma in Indonesia.Methods : This study Retrospective analytic descriptive study of 121 glioma patients fromjanuari 2009 until december 2014. The data was obtained from medical records and indivualcontact via telephone. Tumor response was evaluated in 22 patients with pre and postirradiation imaging (CT or MRI) using 3D volumetric data and assessed via RECISTcriteria.Results : Most of our patients were male (53,7%), with median age 45 years old.Astrocytoma was the most histopathological type found. 70.9% of Patients who receivedradiotherapy in Cipto Mangunkusumo hospital were post craniotomi tumor removal. 3DConformal technique was used in 81.0% of patients. Seventy nine point three had a two graydose perfraction. Provision of chemotherapy in patients undergoing radiation still only at7.4% of patients. Nimotuzumab as a monoclonal antibody used on 9% patient. The medianoverall treatment time was 45 days and delay treatment time 38 days. Fifty nine point onepercent of partial respon was found. Local recurrences were found throughout the follow-upof 6.6%. Analysis kaplan meyer showed that overall treatment time was a prognostic factorfor overal survival rate (p=0,016).Conclusions : : Almost seventy one percent of glioma patients who received radiotherapyhad craniotomy removal tumor. 3D Conformal techniques is the most widely used. Fifty ninepoint one percent of partial respon founded. Three years overall survival was 46,2% andoverall treatment time was found as a factor that significantly affects overall survivalprognosis.;Introduction : Glioma is the most common type of primary intracerebral neoplasms. Highgrade glioma being the most frekuent type found (70,9%) causes a high morbidity andmortality rate. There is currently no data describing the profile management of patientsundergoing radiotherapy glioma in Indonesia.Methods : This study Retrospective analytic descriptive study of 121 glioma patients fromjanuari 2009 until december 2014. The data was obtained from medical records and indivualcontact via telephone. Tumor response was evaluated in 22 patients with pre and postirradiation imaging (CT or MRI) using 3D volumetric data and assessed via RECISTcriteria.Results : Most of our patients were male (53,7%), with median age 45 years old.Astrocytoma was the most histopathological type found. 70.9% of Patients who receivedradiotherapy in Cipto Mangunkusumo hospital were post craniotomi tumor removal. 3DConformal technique was used in 81.0% of patients. Seventy nine point three had a two graydose perfraction. Provision of chemotherapy in patients undergoing radiation still only at7.4% of patients. Nimotuzumab as a monoclonal antibody used on 9% patient. The medianoverall treatment time was 45 days and delay treatment time 38 days. Fifty nine point onepercent of partial respon was found. Local recurrences were found throughout the follow-upof 6.6%. Analysis kaplan meyer showed that overall treatment time was a prognostic factorfor overal survival rate (p=0,016).Conclusions : : Almost seventy one percent of glioma patients who received radiotherapyhad craniotomy removal tumor. 3D Conformal techniques is the most widely used. Fifty ninepoint one percent of partial respon founded. Three years overall survival was 46,2% andoverall treatment time was found as a factor that significantly affects overall survivalprognosis.;Introduction : Glioma is the most common type of primary intracerebral neoplasms. Highgrade glioma being the most frekuent type found (70,9%) causes a high morbidity andmortality rate. There is currently no data describing the profile management of patientsundergoing radiotherapy glioma in Indonesia.Methods : This study Retrospective analytic descriptive study of 121 glioma patients fromjanuari 2009 until december 2014. The data was obtained from medical records and indivualcontact via telephone. Tumor response was evaluated in 22 patients with pre and postirradiation imaging (CT or MRI) using 3D volumetric data and assessed via RECISTcriteria.Results : Most of our patients were male (53,7%), with median age 45 years old.Astrocytoma was the most histopathological type found. 70.9% of Patients who receivedradiotherapy in Cipto Mangunkusumo hospital were post craniotomi tumor removal. 3DConformal technique was used in 81.0% of patients. Seventy nine point three had a two graydose perfraction. Provision of chemotherapy in patients undergoing radiation still only at7.4% of patients. Nimotuzumab as a monoclonal antibody used on 9% patient. The medianoverall treatment time was 45 days and delay treatment time 38 days. Fifty nine point onepercent of partial respon was found. Local recurrences were found throughout the follow-upof 6.6%. Analysis kaplan meyer showed that overall treatment time was a prognostic factorfor overal survival rate (p=0,016).Conclusions : : Almost seventy one percent of glioma patients who received radiotherapyhad craniotomy removal tumor. 3D Conformal techniques is the most widely used. Fifty ninepoint one percent of partial respon founded. Three years overall survival was 46,2% andoverall treatment time was found as a factor that significantly affects overall survivalprognosis., Introduction : Glioma is the most common type of primary intracerebral neoplasms. Highgrade glioma being the most frekuent type found (70,9%) causes a high morbidity andmortality rate. There is currently no data describing the profile management of patientsundergoing radiotherapy glioma in Indonesia.Methods : This study Retrospective analytic descriptive study of 121 glioma patients fromjanuari 2009 until december 2014. The data was obtained from medical records and indivualcontact via telephone. Tumor response was evaluated in 22 patients with pre and postirradiation imaging (CT or MRI) using 3D volumetric data and assessed via RECISTcriteria.Results : Most of our patients were male (53,7%), with median age 45 years old.Astrocytoma was the most histopathological type found. 70.9% of Patients who receivedradiotherapy in Cipto Mangunkusumo hospital were post craniotomi tumor removal. 3DConformal technique was used in 81.0% of patients. Seventy nine point three had a two graydose perfraction. Provision of chemotherapy in patients undergoing radiation still only at7.4% of patients. Nimotuzumab as a monoclonal antibody used on 9% patient. The medianoverall treatment time was 45 days and delay treatment time 38 days. Fifty nine point onepercent of partial respon was found. Local recurrences were found throughout the follow-upof 6.6%. Analysis kaplan meyer showed that overall treatment time was a prognostic factorfor overal survival rate (p=0,016).Conclusions : : Almost seventy one percent of glioma patients who received radiotherapyhad craniotomy removal tumor. 3D Conformal techniques is the most widely used. Fifty ninepoint one percent of partial respon founded. Three years overall survival was 46,2% andoverall treatment time was found as a factor that significantly affects overall survivalprognosis.]"

"Latar Belakang : Kejadian AKI di unit perawatan intensif berhubungan dengan peningkatan mortalitas, morbiditas pasca AKI dan biaya perawatan tinggi. Penelitian mengenai faktor-faktor yang berhubungan dengan mortalitas pasien AKI di unit perawatan intensif di Indonesia khususnya RSUPN dr. Cipto Mangungkusumo belum pernah dilakukan.Tujuan: Mengetahui prevalensi AKI, angka mortalitas pasien AKI, dan faktor- faktor yang berhubungan dengan peningkatan mortalitas pasien AKI di unit perawatan intensif di ICU RSUPN dr. Cipto Mangunkusumo.Metode : Penelitian kohort retrospektif terhadap seluruh AKI di unit perawatan intensif di RSUPN Cipto Mangunkusumo periode Januari 2015 ndash; Desember 2016. Dilakukan analisis hubungan bivariat saampai dengan multvariat dengan STATA Statistics 15.0 antara faktor usia >60 tahun, sepsis, ventilator, durasi ventilator, dialisis, oligoanuria, dan skor APACHE II saat admisi dengan mortalitas. Hasil : Prevalensi pasien AKI di unit perawatan intensif didapatkan 12,25 675 dari 5511 subjek dan sebanyak 220 subjek 32,59 dari 675 subjek yang dianalisis meninggal di unit perawatan intensif. Faktor-faktor yang berhubungan dengan peningkatan mortalitas pada analisis multivariat adalah sepsis OR 6,174; IK95 3,116-12,233 , oligoanuria OR 4,173; IK95 2,104-8,274 , ventilator OR 3,085; IK95 1,348-7,057 , skor APACHE II saat admisi 1/2 [OR 1,597; IK95 1,154-2,209], dan durasi ventilator OR 1,062; IK95 1,012-1,114 . Simpulan : Prevalensi pasien AKI dan angka mortalitasnya di unit perawatan intensif RSUPN dr. Cipto Mangunkusumo didapatkan sebesar 12,25 dan 32,59 . Sepsis, oligoanuria, ventilator, skor APACHE II saat admisi 1/2, dan durasi ventilator merupakan faktor-faktor yang berhubungan bermakna dengan peningkatan mortalitas pasien AKI di unit perawatan intensif. Kata Kunci : Acute Kidney Injury, Faktor Risiko, Mortalitas, Unit Perawatan Intensif

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Background Acute kidney Injury AKI in ICU associated with increased mortality rate, morbidity post AKI, and high health care cost. There is no previous study about factors associated with mortality of AKI patients in ICU in Indonesia, especially at dr. Cipto Mangunkusumo National Central General Hospital.Aim To identify prevalence, mortality rate, and factors associated with mortality of AKI patients in ICU.Method This is a retrospective cohort study. Data were obtained from all of medical records of AKI patients period January 2015 until December 2016 in ICU at Cipto Mangunkusumo hospital. Association of risk factors age 60 years old, sepsis, ventilator, duration of ventilator, oligoanuria, and APACHE II score at admission and mortality will be analyzed using STATA Statistics 15.0. Results AKI prevalence in ICU was 12,25 675 subjects from total 5511 subjects . A total of 220 subjects out of 675 subjects AKI died at ICU. Sepsis OR 6,174 95 CI 3,116 12,233 , oligoanuria OR 4,173 95 CI 2,104 8,274 , ventilator OR 3,085 95 CI 1,348 7,057 , APACHE II score at admission 1 2 OR 1,597 95 CI 1,154 2,209 , and duration of ventilator OR 1,062 95 CI 1,012 1,114 . were significant factors associated with mortality of AKI patients in ICU. Conclusion AKI prevalence and mortality rate in ICU at dr. Cipto Mangunkusumo National Central General Hospital were 12,25 and 32,59 . Sepsis, oligoanuria, ventilator, APACHE II score at admission 1 2, and duration of ventilator were significant factors associated with mortality of AKI patients in ICU. Keywords Acute Kidney Injury, Intensive Care Unit, Mortality, Risk Factor "

"Kecemasan pra operasi merupakan kondisi yang lazim dialami oleh pasien yang akan menjalani tindakan pembedahan. Tingkat kecemasan pra operasi yang tinggi dapat memberikan dampak negatif terhadap pasien. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi tingkat kecemasan pra operasi pada pasien-pasien yang menjalani operasi di Instalasi Pelayanan Bedah Terpadu RSUPN dr. Cipto Mangunkusumo. Penelitian ini menggunakan desain cross- sectional dengan 393 responden yang diseleksi melalui metode consecutive sampling. Skala kecemasan menggunakan The Amsterdam Preoperative and Anxiety Scale (APAIS). Data dianalisis dengan menggunakan analisis bivariat dan multivariat. Gambaran tingkat kecemasan pra operasi sebesar 54.2%. Tidak ada hubungan signifikan antara usia, jenis kelamin, tingkat pendidikan, status pekerjaan, pernikahan, jenis operasi, dan pembiusan terhadap tingkat kecemasan pra operasi (p > 0.05). Jenis operasi merupakan variabel yang paling berpengaruh terhadap tingkat kecemasan pra operasi (OR = 3.501;CI = 95%). Studi lebih lanjut dibutuhkan untuk mengidentifikasi faktor yang secara spesifik berpengaruh terhadap tingkat kecemasan pra operasi.

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Preoperative anxiety is a common condition experienced by patients who will undergo a surgery. High levels of preoperative anxiety can cause negative impacts on patients. This study aims to analyze the factors that influence the level of preoperative anxiety in patients undergoing surgery at the Integrated Surgical Service of Cipto Mangunkusumo National Center Hospital. This study used a cross-sectional design with 393 respondents selected through consecutive sampling method. The anxiety scale are measured by The Amsterdam Preoperative and Anxiety Scale (APAIS). Data were analyzed using bivariate and multivariate analysis. The description of the level of preoperative anxiety was 54.2%. There was no significant relationship between age, gender, education level, employment status, marriage, type of surgery, and anesthesia on the level of preoperative anxiety (p > 0.05). Types of surgery is the variable that mostly influenced the level of preoperative anxiety (OR = 3.501; CI = 95%). Further studies are needed to identify factors that specifically influence the level of preoperative anxiety."

"Varises esofagus (VE) merupakan salah satu komplikasi hipertensi vena porta yang serius. Pemanfaatan teknologi informasi dalam pelayanan keperawatan dapat membantu memonitor kondisi klien sirosis hepatis setelah perawatan di Rumah Sakit. Meskipun sebagian edukasi diterima dengan baik, seringkali edukasi yang diberikan kurang optimal, khususnya pada pasien berobat jalan di poliklinik. Penelitian ini bertujuan untuk menganalisis efektivitas edukasi melalui WebApps pencegahan perdarahan berulang varises esofagus terhadap pengetahuan pasien sirosis hepatis di RSUP Nasional Dr. Cipto Mangunkusumo. Metode penelitian ini menggunakan Kuasi Eksperimen dengan Nonequivalent Kontrol Group Design. Sample dipilih secara purposive sebanyak 132 responden dengan 66 pada kelompok kontrol dan 66 pada kelompok intervensi. Hasil penelitian menunjukkan tidak ada hubungan signifikan antara kelompok usia, jenis kelamin, pekerjaan, dengan pengetahuan (p>0,05). Lama rawat (0,05). Pendidikan (rendah, menengah, tinggi) tidak menunjukkan perbedaan signifikan dalam nilai pengetahuan pre-test dan post-test pada kelompok intervensi. Meskipun terdapat variasi, nilai pre-test dan post-test pada semua tingkat pendidikan tidak berbeda secara signifikan. Kesimpulan penelitian ini bahwa karakteristik responden seperti usia, jenis kelamin, pekerjaan tidak berhubungan signifikan dengan pengetahuan, meskipun pendidikan sedikit memiliki variasi nilai, namun tidak signifikan. Sedangkan lama rawat hanya signifikan pada pengetahuan pretest.

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Esophageal varices (VE) is one of the serious complications of portal vein hypertension. Utilization of information technology in nursing services can help monitor the condition of hepatic cirrhosis clients after hospitalization. Although some education is well received, often the education provided is not optimal, especially for outpatients at the polyclinic. This study aims to analyze the effectiveness of education through WebApps to prevent recurrent bleeding of esophageal varices on the knowledge of patients with hepatic cirrhosis at Dr. Cipto Mangunkusumo National Hospital. This research method uses Quasi Experiment with Nonequivalent Kontrol Group Design. The sample was purposively selected as many as 132 respondents with 66 in the kontrol group and 66 in the intervention group. The results showed no significant relationship between age group, gender, occupation, and knowledge (p>0.05). Length of stay (0.05). Education (low, middle, high) showed no significant difference in pre-test and post-test knowledge scores in the intervention group. Despite the variation, the pre-test and post-test scores at all education levels were not significantly different. The conclusion of this study is that the characteristics of respondents such as age, gender, occupation are not significantly related to knowledge, although education has a slight variation in value, but not significant. While the length of hospitalization is only significant in pre-test knowledge."