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Ummu Hani
"ABSTRAK
Latar belakang: Selama beberapa hari setelah persalinan, retensio urin dengan distensi kandung kemih adalah fenomena yang umum terjadi. Jika pasien tidak dapat berkemih spontan dalam waktu 4 jam setelah bersalin, besar kemungkinan bahwa dia mengalami Retensio Urin Post Partum RUPP . Di beberapa tempat pengukuran residu urin dilakukan 4 jam post partum, sementara di tempat lain dilakukan 6 jam post partum. Ketidakseragaman waktu pengukuran ini akan mempengaruhi diagnosis, tata laksana, serta prognosis. Waktu pengukuran yang lebih lama akan menyebabkan kandung kemih akan terisi lebih banyak urin, sehingga akan terdistensi dalam waktu yang lebih lama, sehingga waktu pemulihan akan lebih lama.Objektif: Diketahuinya lama pemulihan dan volume residu urin pada kelompok pasien dengan retensio urin pasca persalinan dengan beda waktu pengukuran,Desain penelitian dan metode: Penelitian ini menggunakan desai uji klinis acak di RSUPN Cipto Mangunkusumo dan RSUD Karawang bulan Maret-Desember 2017. Perermpuan pasca salin dengan risiko retensio urin pasca persalinan, bersedia mengikuti penelitian, dan terdiagnosis retensio urin dibagi menjadi dua kelompok. Kelompok pertama diukur residu urinnya dalam 4 jam, kelompok kedua dalam 6 jam. Pasien lalu diberikan tatalaksana retensio urin sesuai protokol RSUPNCM dan dicatat waktu pulihnya.Hasil: Karakteristik pasien pada kedua kelompok dianggap setara. Median lama pemulihan pasien retensio urin yang diukur residu urin 4 jam adalah 30 jam, berbeda 21 jam dengan pasien yang diukur resiudnya 6 jam, yaitu 51 jam p

ABSTRACT
Introduction Few days after delivery, urinary retention with bladder distention commonly happens. If patient unable to void spontaneously 4 hours after delivery, most likely she will develops post partum urinary retention PPUR . In some hospitals, the urinary residual volume was measured at 4th hour, other measures at 6th hour post delivery. This will affects the diagnosis, management, and prognosis. The longer the measurement will make the bladder filled with much more urine volume, thus the bladde will be distended in longer period, so the recovery time will be prolonged.Objective To know the differrence of recovery time and the urinary residual volume between group of patient with different time of urinary residual collecting.Study design and methode A randomized controlled trial was held at Cipto Mangunkusumo central general hospital and central Karawang hospital between March and Desember 2017. Post partum women with urinary retention risks, willing to contribute to the trial, and diagnosed as post partum urinary retention were divided into 2 groups. Urinary residual volume was meassured in 4th hour and 6th hour in each group. Patient then treated according to RSCM guideline, and the time of recovery was documented.Result Both group have similar characteristic. The median length of recovery in the group which the urinary residual was measured in 4th hour was 30 hours, 21 hours shorter than 6th hour group, 51 hours p 0.001 . The median of urinary residual volume of the 4th hour group was 600 ml, 400 ml lesser than the 6th hour group, 1000 ml p 0.001 Conclussion time of recovery are shorter in the 4th hour group and the urinary residual volume are less in the 4th hour group compared to the 6th hour group.Keywords post partum urinary retention, urine residual, urinary residual collecting time"
Depok: 2017
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Marliana Sri Rejeki
"Latar belakang Sisplatin merupakan pengobatan utama untuk karsinoma nasofaring KNF , tetapi berpotensi menimbulkan nefrotoksisitas. Selain kadar BUN dan kreatinin serum, KIM-1 dan NGAL diduga cukup sensitif untuk mendeteksi nefrotoksisitas. Penelitian ini bertujuan untuk mengevaluasi kadar KIM-1 dan NGAL dalam urin untuk mendeteksi gangguan fungsi ginjal pada pasien KNF stadium lanjut yang mendapatkan kemoterapi berbasis sisplatin.
Metode: Penelitian ini merupakan penelitian kohort prospektif. Subyek penelitian dibagi dalam 3 kelompok: pasien yang belum pernah terpapar dan yang sudah pernah mendapatkan kemoterapi berbasis sisplatin 75-100 mg/m serta pasien yang belum pernah mendapatkan kemoterapi sisplatin dan kemudian diberi sisplatin 40 mg/m 2 . Kadar KIM-1, NGAL dalam urin serta kadar BUN dan kreatinin dalam serum diukur pada saat sebelum dan sesudah mendapatkan sisplatin pada ketiga kelompok. Analisis statistik yang digunakan adalah uji ANOVA, uji Pearson, Spearman, Kolmogorov-Smirnov dan SPSS versi 22,0.
Hasil: Terdapat perbedaan selisih kadar BUN yang bermakna antara sebelum dan sesudah diterapi pada ketiga kelompok p=0.0001 . Perbedaan selisih kadar NGAL dalam urin pada penelitian ini juga berbeda bermakna antara sebelum dan sesudah diterapi terhadap ketiga kelompok p=0,025 , tetapi ada perbedaan rerata pada sepasang kelompok yang bermakna hanya didapatkan pada kelompok yang belum pernah dikemoterapi 40 mg/m 2 dan kelompok yang sudah pernah diberi kemoterapi 75-100 mg/m 2 p=0,02. Perbedaan selisih kadar KIM-1 tidak bermakna pada ketiga kelompok p=0,275.
Kesimpulan: Sisplatin menunjukkan akumulasi nefrotoksisitas yang tergantung pada dosis dose-dependent manner . Pengukuran kadar NGAL dalam urin dapat mendeteksi nefrotoksisitas tahap dini, tetapi belum bisa menggantikan peran BUN. Pengukuran kadar KIM-1 dalam urin tidak dapat mendeteksi gangguan fungsi ginjal.

Background: Cisplatin is the main treatment for nasopharyngeal carcinoma NPC with a potency of causing nephrotoxicity. In addition to serum BUN and creatinine levels, KIM 1 and NGAL levels is assumed to be quite sensitive in detecting nephrotoxicity. The study was aimed to evaluate urinary KIM 1 and NGAL level to detect kidney dysfunction in patients with advanced stage NPC who received cisplatin based chemotherapy.
Method: The study was a cohort prospective study. Subjects were categorized into 3 groups, i.e. patients who had never received and who had received 75 100 mg m2 cisplatin based chemotherapy as well as those who had never received any cisplatin based chemotherapy and were subsequently received 40 mg m cisplatin. The levels of urinary KIM 1, NGAL and serum level of BUN and creatinine were measured before and after receiving cisplatin in the three groups. Statistical analysis used in our study were ANOVA, Pearson, Spearman, KolmogorovSmirnov test and SPSS version 22.0.
Results: There was a significant difference of delta BUN level before and after treatment in all three groups p 0.0001 . Delta urinary NGAL level was also significantly different between before and after treatment in all groups p 0.025 however, a significant mean difference of a pair group was only found between those who never had 40 mg m 2 chemotherapy and those who had received 75 100 mg m 2 chemotherapy p 0.02 while delta KIM 1 level showed no significant difference in all three groups p 0.275.
Conclusion: Cisplatin may cause accumulated nephrotoxicity, which has dosedependent manner. Measuring urinary NGAL level can detect an early stage of kidney dysfunction however, it still cannot replace the role of BUN. Measurement of urinary KIM 1 level cannot detect kidney dysfunction.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2017
SP-Pdf
UI - Tugas Akhir  Universitas Indonesia Library
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"This new volume fills the gap in the literature as it will guide urologists and pathologists in the proper utilization of a variety of laboratory methods that are currently available to determine the presence, persistence or progression of tumors of the lower urinary tract. The volume emphasizes cytology of the urinary tract which is preferred over other methods (i.e. biochemical, immunological and cytogenetic) for its accuracy, especially for the important high grade tumors. This volume will appeal to urologists as well as pathologists, cytopathologists and related professions. The illustrations, nearly all in color, stress the key points of the text and enhance basic understanding of urothelial and other tumors of the urinary tract.
"
New York: Springer, 2012
e20426516
eBooks  Universitas Indonesia Library
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Nathania Amanda Nugraha
"Inkontinensia urin atau hilangnya kontrol kandung kemih, sangat umum terjadi akibat perubahan terkait usia. Perubahan terkait usia ini dapat mempengaruhi fungsi berkemih pada lansia. Seiring bertambahnya usia, hipertrofi otot kandung kemih dan penebalan dinding kandung kemih mengganggu kemampuan kandung kemih untuk mengembang. Saat kandung kemih meregang mencapai kapasitas maksimum, detrusor berkontaksi dan dapat menyebabkan inkontinensia urin. Prompted voiding merupakan intervensi dimana perawat atau caregiver secara konsisten dalam interval waktu tertentu mengajak dan membantu lansia untuk berkemih. Prompted voiding memiliki tiga prinsip utama yaitu prompt, puji, dan monitor. Prompt dilakukan untuk mendorong dan membantu lansia menggunakan toilet secara berkala. Pujian artinya pengasuh memberikan pujian saat lansia mampu menahan urin sampai jadwal selanjutnya. Serta monitor secara berkala apakah pasien perlu menggunakan toilet dan intake cairan lansia. Tujuan karya ilmiah ini adalah untuk memberikan gambaran mengenai penerapan prompted voiding pada pasien dengan inkontinensia urin. Hasil yang didapatkan selama lima belas hari melakukan intervensi, menunjukan adanya penurunan skor Incontinence Scale Index (ISI) dari 8 menjadi 3. Sehingga terdapat penurunan skor inkontinensia urin sebesar 62,5%. Tingkat keparahan klien menurun dari inkontinensia parah menjadi inkontinensia sedang. Intervensi ini dapat di terapkan pada lansia yang tinggal di panti werdha sebagai intervensi untuk menurunkan tingkat keparahan inkontinensia urin pada lansia.

Urinary incontinence or loss of bladder control, is very common as a result of age-related changes. These age-related changes can affect urinary function in the elderly. As people age, bladder muscle hypertrophy and bladder wall thickening will impair the bladder's ability to expand. When the bladder is stretched to its maximum capacity, the detrusor contracts and can cause urinary incontinence. Prompted voiding is an intervention where the nurse or caregiver consistently invites and helps the elderly to urinate. Prompted voiding has three main principles prompt, praise, and monitor. Prompts are carried out to encourage and help the elderly to use the toilet regularly. Praise means that caregivers give praise when the elderly are able to hold urine until the next schedule. Last, monitor regularly whether the patient needs to use the toilet and the elderly fluid intake. This scientific paper aimed to provide an overview of prompted voiding application in elderly with urinary incontinence. The results obtained after fifteen day intervention, showed a decrease in the Incontinence Scale Index (ISI) score from 8 to 3. So there was a decrease in urinary incontinence score by 62.5%. The severity of the client decreased from severe incontinence to moderate incontinence. Therefore, this intervention can be applied to the elderly living in nursing homes to reduce the severity of urinary incontinence in the elderly."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2022
PR-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Dewita Nilasari
"Latar Belakang: Inkontinensia urin tipe tekanan (IUT) merupakan gangguan uroginekologi yang relatif sering ditemukan pada ibu hamil. Perubahan anatomis, hormonal dan jaringan yang dialami oleh perempuan hamil membuatnya rentan untuk mengalami IUT. IUT secara signifikan dapat mengganggu kualitas hidup ibu hamil. Studi tentang prevalensi IUT telah dilakukan di Indonesia tetapi sampai saat ini belum ada penelitian yang menilai prevalensinya pada perempuan primigravida trimester ketiga akhir yang cenderung lebih rentan mengalami kondisi SUI persisten postpartum. Selain itu, penelitian tentang parameter ultrasonografi (USG) pada pasien IUT pada ibu hamil belum dilakukan di Indonesia. Studi tersebut penting untuk mengetahui prevalensi IUT pada perempuan primigravida akhir trimester ketiga serta hubungan kondisi IUT dengan parameter USG untuk mobilitas leher kandung kemih.
Tujuan: Tujuan dari penelitian ini adalah untuk mengetahui prevalensi IUT pada perempuan primigravida trimester ketiga akhir di Jakarta, Indonesia selama periode 1 November 2016 sampai 31 Juli 2019. Penelitian ini juga mengidentifikasi pasien karakteristik yang secara signifikan berkorelasi dengan IUT. Selanjutnya, penelitian ini menguji korelasi antara parameter USG yang terdiri dari penurunan leher kandung kemih (BND), sudut retrovesikal (RVA), sudut rotasi uretra (RoU), dan funneling dengan IUT pada pasien tersebut.
Metode: Penelitian ini merupakan bagian dari penelitian besar mengenai penggunaan USG dasar panggul pada perempuan dengan berbagai jenis disfungsi dasar panggul di DKI Jakarta. Sebagian data merupakan data sekunder dari penelitian besar sementara sebagian lainnya dikumpulkan oleh peneliti. Penelitian ini menggunakan metode cross-sectional untuk menemukan prevalensi IUT pada perempuan primigravida trimester ketiga akhir di DKI Jakarta. Kemudian, penelitian cross-sectional komparatif dilakukan untuk pengukuran parameter USG berupa BND, RVA, RoU dan funneling. Diagnosis IUT dilakukan melalui anamnesis, pemeriksaan fisik, serta Kuesioner Diagnosis Inkontinensia Urin (QUID) dan tes batuk stres. Sebanyak 30 subjek yang terdiagnosis IUT dan 30 subjek tanpa IUT yang memenuhi kriteria penelitian dipilih dan dikumpulkan datanya dengan formulir dan database penelitian. Data awalnya dikumpulkan dalam perangkat lunak Microsoft Excel dan kemudian diperiksa dan diberi kode untuk dianalisis dalam SPSS versi 25 untuk Mac. Data kategoris disajikan sebagai frekuensi (persentase) sedangkan data numerik kontinu disajikan sebagai mean + standar deviasi untuk data yang terdistribusi normal serta median (rentang) untuk data yang tidak berdistribusi normal. Signifikansi statistik dinyatakan sebagai 0,05. Analisis kurva karakteristik receiver-operator digunakan untuk mendapatkan nilai cut-off BND, RVA, dan RoU yang secara signifikan berhubungan dengan IUT antara sensitivitas dan spesifisitasnya. Analisis bivariat dilakukan untuk membandingkan faktor risiko IUT yang signifikan secara statistik. Pearson chi-square atau uji eksak Fisher digunakan untuk analisis bivariat kategoris sementara uji T tidak berpasangan atau Mann Whitney digunakan untuk analisis perbedaan rerata. Analisis multivariat menggunakan regresi logistik kemudian dilakukan untuk mengidentifikasi faktor risiko independen IUT dan untuk mendapatkan rasio odds yang disesuaikan dari prediktor.
Hasil: dari 209 perempuan primigravida trimester ketiga akhir, inkontinensia urin tipe tekanan diamati pada 57 pasien, sehingga prevalensinya sebesar 27,3%. Faktor risiko IUT yang teridentifikasi adalah indeks massa tubuh (IMT) lebih dari 23 kg/m2 (P=0,037), RVA lebih dari 155,020 (P=0,002), serta adanya funneling pada USG translabial. Nilai rerata BND (1,78 + 0,64 cm) dan rerata RVA (158,04 + 14,460) secara signifikan lebih tinggi dibandingkan kelompok non-IUT, dengan P=0,044 dan P=0,001. Sedangkan nilai rerata RoU tidak berbeda bermakna dengan non-IUT. Nilai cut-off untuk BND, RVA, dan RoU yang digunakan untuk mengkategorikan pasien berisiko tinggi masing-masing adalah 1,77 cm, 155,020, dan 27,830. Pada analisis multivariat, hanya IMT (P=0,05, aOR 3,73) dan funneling positif (P=0,03, aOR 4,3) yang terbukti sebagai faktor risiko independen IUT. Prevalensi IUT di antara primigravida trimester ketiga akhir lebih rendah dibandingkan penelitian lain. Faktor risiko IUT yang diidentifikasi dengan data ini sesuai dengan penelitian sebelumnya baik di Indonesia maupun di luar negeri.
Kesimpulan: Prevalensi IUT di antara primigravida trimester ketiga akhir adalah 27,3% dan diperoleh mean serta nilai batas untuk parameter USG BND, RVA dan RoU untuk pasien tersebut. Hanya funneling positif serta IMT yang terbukti menjadi faktor risiko independen IUT.

Background: Stress urinary incontinence is a relatively common urogynecological disorder in a pregnant women. The gross anatomical as well as hormonal and tissue changes encountered by pregnant women posed themselves prone to acquire SUI. SUI can significantly disrupts pregnant women’s quality of life. Studies about the prevalence of SUI have been conducted in Indonesia but up to now, there is no study assessing its prevalence on late third trimester primigravid women which are likely more prone to have persistent condition after the delivery. Besides, study about the ultrasound parameters in SUI patients among pregnant women has not been conducted in Indonesia.
Purpose: The aim of this study is to find the prevalence of SUI among late third trimester primigravid women in Jakarta, Indonesia during the period of November, 2016 until July, 2019. This study also attempts to identify the patients’ characteristics that significantly correlate with SUI. Furthermore, this study examines the correlation between ultrasound parameters comprising of bladder neck descent (BND), retrovesical angle (RVA), rotational of urethra (RoU), and funneling with SUI in such patients.
Method: This study is part of a study about the utilization of pelvic ultrasonography for patients with various pelvic floor dysfunction in the Greater Jakarta region. Some parts of the data were secondary data obtained from the main studies while the rest were collected by the author herself. This study employs a descriptive-observational cross-sectional method for the investigation of SUI prevalence in the late third trimester primigravid women from the cohort. Furthermore, a comparative cross-sectional study was conducted involving a total of 60 subjects which were equally divided into two groups, the SUI group and non-SUI group. The diagnosis of SUI was conducted through history taking, physical examination, as well as Questionnaire for Urinary Incontinence Diagnosis (QUID) and stess cough test. The subjects of each group were consecutively selected from the cohort and their anthropological, clinical, as well as recent BND, RVA, RoU and funneling data from ultrasound records were collected. Data were initially collected in a Microsoft Excel software and then were checked and coded to be analyzed in SPSS version 25 for Mac. Categorical data were presented as number (percentage) while continuous numeric data were presented as mean + standard deviation for normally distributed data as well as median (range) for data with no normal distribution. Statistical significance was stated as 0,05. A receiver-operator characteristics curve analysis was employed to obtain the cut-off value of BND, RVA, and RoU which were significantly associated with SUI among with their sensitivity and specifity. Bivariate analysis was conducted to compare the statistically significant risk factors of SUI. Pearson chi-square or Fisher exact test were used for categorical bivariate analysis while unpaired T-test or Mann Whitney were used for mean difference analysis.  Multivariate analysis using logistic regression were then conducted to identify the independent predictors of SUI and to obtain the adjusted odds ratio of the predictors.
Results: from 209 late third trimester primigravid women, stress urinary incontinence was observed in 57 patients, giving the prevalence of 27,3%. The identified risk factors of SUI were a body mass index more than 23 kg/m2 (P=0,037), RVA of more than 155,02 degrees (P=0,002), as well as the presence of funneling in the translabial ultrasound. The mean value of BND (1,78 + 0,64 cm) as well as mean RVA (158,04 +14,46 degrees) were significantly higher than that of control group, with P=0,044 and P=0,001 respectively. Meanwhile, mean RoU value were not significantly different with control. The cut-off value for BND, RVA, and RoU which were used to categorize patient as high-risk were 1,77 cm, 155,02 degrees, as well as 27,83 degrees respectively. In the multivariate analysis, only BMI (P=0,05, aOR 3,73) and positive funneling (P=0,03, aOR 4,3) which were shown to be independent predictors of SUI. The prevalence of SUI among late third trimester primigravid were lower than that of other studies. The risk factors of SUI identified with this data were in accordance with the other previous studies from Indonesia as well as overseas.
Conclusion: The prevalence of SUI among the cohort of late third trimester primigravid was 27.3 percent and the mean as well as cut-off values for ultrasound parameter of BND, RVA and RoU for such patients were obtained. Only positive funneling as well as BMI were shown to be the independent risk factors of SUI.
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2022
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Retnaning Kurniawati
"ABSTRAK
Tingkat pendidikan orang tua anak usia sekolah yang rendah menyebabkan mereka tidak mampu memberikan pola asuh yang adekuat. Akibatnya anak gagal memenuhi tugas perkembangannya, salah satunya adalah kemandirian dalam melakukan personal hygiene. Kegagalan ini menimbulkan ketidakteraturan anak untuk pergi ke toilet, dan terjadi dysfunctional avoiding yang menimbulkan enuresis. Enuresis juga dapat disebabkan oleh banyak faktor, salah satunya adalah overactive bladder. Ketidakteraturan untuk pergi ke toilet, dysfunctional avoiding, dan overactive bladder juga terjadi pada An. H dari keluarga Bapak P, sehingga ia mengalami enuresis. Intervensi dan implementasi unggulan yang dilakukan adalah bladder training dengan pendekatan keperawatan keluarga. Tujuannya adalah untuk memberdayakan keluarga agar mampu menciptakan keteraturan pola berkemih pada An. H. Hasil evaluasi menunjukkan adanya penurunan frekuensi terjadinya enuresis dan peningkatan tingkat kemandirian keluarga.

ABSTRACT
The low education level of parents of school aged children causes them to be unable to provide adequate parenting. As a result the child failed to fulfill the task of development. One of which is the independence in doing personal hygiene. This failure causes child irregularity to go to the toilet, and dysfunctional avoiding causes enuresis. Enuresis can also be caused by many factors, one of which is the overactive bladder. Irregularities to go to the toilet, dysfunctional avoiding, and overactive bladder also occur in school aged child named H, from Mr. P 39 s family, so he experiences enuresis. The superior interventions and implementation are bladder training with family nursing approach. The goal is to empower families to be able to create regular urinary patterns on H. The results of the evaluation showed a decrease in the frequency of enuresis and increased family self reliance."
2017
PR-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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"Urolithiasis refers to formation of stone in the kidney, ureter, or bladder. Several studies showed metabolic abnormalities were common in urolithiasis patients. The aim of this study was to describe the association between body-mass-index (BMI), serum uric acid, serum glucose, and blood pressure toward stone opacity in urinary tract stone patients. This study was done retrospectively by reviewing registry data of urinary tract stone patients that had undergone ESWL on January 2008 - December 2013 in Department of Urology Cipto Mangunkusumo Hospital. Data concerning body mass inde, serum uric acid, serum glucose, blood pressure, and urinary tract stone opacity were recorded. Associations between body mass index, serum uric acid, serum glucose and blood pressure with urinary tract stone opacity were analyzed using chi-square test. There were 2,889 patients who underwent ESWL on January 2008-December 2013. We analyzed 242 subjects with complete data. Mean age was +-12.78 (48.02 years). Male -to-female ratio was 2.27:1 Mean BMI was +-3.78 (29.91 kg/m2). High risk BMIs were found in 161 patients (66.52%). The proportion of radioopaque stone was 77.69% (188 patients). Twenty two patients (9.1%) had normal blood pressure. Patients with high serum uric were 34.30% (83 patients). We found a significant association between random serum glucose level and stone opacity (p<0.05). There is an association between random serum glucose level and stone opacity in urolithiasis patients. Hyperglycemia patients tend to have radiolucent stone, whereas normoglycemia patients tend to have radioopaque stone."
UI-MJI 24:2 (2015)
Artikel Jurnal  Universitas Indonesia Library
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Restu Hidayasri
"Penilaian karakteristik asimetris dinding nasofaring pada karsinoma nasofaring KNF pasca terapi memiliki implikasi penting pada penatalaksanaan pasien, tetapi seringkali sulit untuk mendiferensiasikan antara lesi tumoral dan non tumoral menggunakan CT scan/ MRI konvensional. Penelitian ini bertujuan untuk mengetahui titik potong nilai ADC antara lesi tumoral dan non tumoral pada follow up MRI pasca terapi. Penelitian merupakan studi kesesuaian dengan pendekatan potong lintang antara nilai ADC dan histopatologi. Penelitian menggunakan data primer 21 pasien KNF pasca kemoradioterapi yang melakukan pemeriksaan MRI nasofaring di Departemen Radiologi RSUPN-CM pada Juni 2016-Oktober 2017. Range of interest dan pemetaan ADC nilai b 1000 s/mm2 diletakkan pada komponen solid. Rerata jarak terapi dan evaluasi MRI pasca terapi adalah 9,3 bulan. Rerata nilai ADC lesi tumoral 0,7 x 10-3 mm2/s SD 0,05 dan non tumoral 1,2 x 10-3 mm2/s SD 0,3. Pada uji independent T-test menunjukkan perbedaan bermakna secara statistik antara rerata nilai ADC tumoral dan non tumoral. Pada analisis ROC nilai ADC didapatkan titik potong 0,86 x 10-3 mm2/s AUC= 0,97; SE= 0,04 dengan nilai sensitivitas 100 dan spesifisitas 93,8. Berdasarkan uji McNemar nilai p> 0,005 menunjukkan bahwa tidak ada perbedaan bermakna antara temuan ADC dan histopatologi. Terdapat kesesuaian yang sangat kuat antara nilai ADC dan histopatologi untuk membedakan lesi tumoral dan non tumoral KNF pasca terapi. Pemeriksaan MRI sekuens DWI-ADC dapat digunakan untuk memberikan informasi tambahan pada kasus follow up KNF pasca terapi.

Assessment of nasopharyngeal wall asymmetric characteristics of post treatment nasopharyngeal carcinoma NPC has important implication for management of the patients, but it is often difficult to distinguish between non tumoral and tumoral lession by using CT scan conventional MRI. The objective is to assess ADC cut off values between tumoral and non tumoral lession on MRI follow up after treatment. This research is a conformity study with cross sectional approach between ADC values compared with histopathology. This study used primary data of 21 post chemoradiotherapy NPC patients, who were examined nasopharnygeal MRI at Radiology Departement of Cipto Mangunkusumo Hospital in June 2016 October 2017. Range of interest ROI and ADC mapping b value 1000 s mm2 were placed on solid components. Mean interval between therapy and post treatment MRI was 9.3 months. Mean ADC values of tumoral lesions were 0.7 x 10 3 mm2 s SD 0.05 and non tumoral lession 1.2 x 10 3 mm2 s SD 0.3 . Independent T test showed statistically significant difference between the mean ADC values in tumoral and non tumoral lesions. In ROC analysis, ADC cut off value was obtained 0,86 x 10 3 mm2 s AUC 0,97 SE 0,04 with 100 sensitivity and 93,8 specificity. Based on the McNemar test p 0,05 , there was no significant difference between ADC findings and histopathology. There is very strong suitability between ADC and histopathologic values to differentiate tumoral and non tumoral lession in post treatment NPC. DWI ADC can be used to provide additional information on follow up post treatment NPC. "
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2017
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Elisia
"ABSTRAK
Latar belakang: Tesis ini bertujuan untuk mengetahui insidens retensio urin
pasca rekonstruksi POP dan faktor-faktor yang berhubungan.Retensio urin
merupakan komplikasi akut tindakan rekonstruksi dan banyak dijumpai pada
prosedur operasi, termasuk operasi POP (POP). Untuk menghindari morbiditas
lebih lanjut, penelitian ini bertujuan untuk mengetahui insidens rertensio urin
pasca rekonstruksi POP faktor-faktor risiko yang berhubungan.
Metode: Penelitian ini adalah penelitian kohort prospektif yang dilaksanakan di
RS Cipto Mangunkusumo dan RS Fatmawati dengan mengikutsertakan wanita
yang hendak mengalami rekonstruksi POP dalam rentang waktu April 2013
hingga April 2015. Kriteria inklusi dan eksklusi subjek meliputi wanita dengan
POP derajat 2,3 dan 4 tanpa riwayat retensio urin sebelumnya, konsumsi obatobatan
yang
dapat menyebabkan retensio urin dan tanpa cedera kandung kemih.
Pasca rekonstruksi, subjek dilakukan pemasangan kateter urin selama 24 jam.
Kemudian, enam jam pasca pelesapan kateter, dilakukan pengukuran residu urin
pada kandung kemih. Retensio urin didefinisikan dengan didapatkannya residu
urin >100 ml.
Hasil: Dari 200 subjek, ditemukan 59 subjek (29,5%) mengalami retensio urin.
Tidak ada hubungan antara faktor risiko umur, Indeks Massa Tubuh (IMT),
derajat POP, derajat sistokel, kejadian infeksi saluran kemih, dan durasi operasi
terhadap retensio urin. Jenis prosedur total vagina hysterectomy + kolporafi
anterior + kolpoperineorafi + sacrospinous fixation dan durasi operasi > 130
menit berhubungan dengan retensio urin dengan RR 3,66 95% IK 2,91-4,60
p<0,001 dan 1,66 95%IK 1,07-2,59 p=0,02, berturut-turut
Kesimpulan: Insidens retensio urin cukup tinggi pasca rekonstruksi POP. Jenis
tindakan rekonstruksi tertentu dan semakin lamanya durasi rekonstruksi
berhubungan dengan kejadian retensio urin.ABSTRACT
Background: The objective of this study was to know the incidence of post
operativeurinaryretention after pelvic organ prolapse surgery and associated
factors.Post operative urinary retention (POUR) is considered as an acute
complication after a surgey in many operative procedures, including pelvic organ
prolpase (POP) surgery. To avoid further morbidity, this study aimed to know the
incidence of POUR after POP surgery and its risk factors.
Methods: This is a prospective cohort study conducted in Cipto Mangunkusumo
hospital and Fatmawati Hospital from April 2013 to April 2015. Subjects were
women who wanted to undergo POP surgery with two to four degree of POP.
Subjects with history of urinary retention, drugs consumption that tend to cause
urinary retention or bladder unjury were excluded. After the reconstruction,
urinary catheter was placed for 24 hours. Then, after six hours, catheter was
removed and residual urine was measured. Urinary retention was defined as
residual urine more than 100 ml.
Results: Of 200 subjects recruited, 59 (29.5%) had POUR. There were no
association between age, body mass index, degree of uterine POPe, degree of
cystocele, urinary tract infectionand POUR. Duration of surgery > 130 minute and
Total vagina hysterectomy +anterior colporraphy + colpoperineorraphy +
sacrospinous fixation procedure and duration of surgery > 130 minute were
associated with POUR (RR 3.66, 2.91-4.60 95% CI, p<0.001 and 1.66 , 072.5995%CI,
p=0.02;
respectively)
Conclusion: POUR incidence after POP surgery was quite high. Type of the
procedure and duration of surgery were associated with POUR.
;Background: The objective of this study was to know the incidence of post
operativeurinaryretention after pelvic organ prolapse surgery and associated
factors.Post operative urinary retention (POUR) is considered as an acute
complication after a surgey in many operative procedures, including pelvic organ
prolpase (POP) surgery. To avoid further morbidity, this study aimed to know the
incidence of POUR after POP surgery and its risk factors.
Methods: This is a prospective cohort study conducted in Cipto Mangunkusumo
hospital and Fatmawati Hospital from April 2013 to April 2015. Subjects were
women who wanted to undergo POP surgery with two to four degree of POP.
Subjects with history of urinary retention, drugs consumption that tend to cause
urinary retention or bladder unjury were excluded. After the reconstruction,
urinary catheter was placed for 24 hours. Then, after six hours, catheter was
removed and residual urine was measured. Urinary retention was defined as
residual urine more than 100 ml.
Results: Of 200 subjects recruited, 59 (29.5%) had POUR. There were no
association between age, body mass index, degree of uterine POPe, degree of
cystocele, urinary tract infectionand POUR. Duration of surgery > 130 minute and
Total vagina hysterectomy +anterior colporraphy + colpoperineorraphy +
sacrospinous fixation procedure and duration of surgery > 130 minute were
associated with POUR (RR 3.66, 2.91-4.60 95% CI, p<0.001 and 1.66 , 072.5995%CI,
p=0.02;
respectively)
Conclusion: POUR incidence after POP surgery was quite high. Type of the
procedure and duration of surgery were associated with POUR.
;Background: The objective of this study was to know the incidence of post
operativeurinaryretention after pelvic organ prolapse surgery and associated
factors.Post operative urinary retention (POUR) is considered as an acute
complication after a surgey in many operative procedures, including pelvic organ
prolpase (POP) surgery. To avoid further morbidity, this study aimed to know the
incidence of POUR after POP surgery and its risk factors.
Methods: This is a prospective cohort study conducted in Cipto Mangunkusumo
hospital and Fatmawati Hospital from April 2013 to April 2015. Subjects were
women who wanted to undergo POP surgery with two to four degree of POP.
Subjects with history of urinary retention, drugs consumption that tend to cause
urinary retention or bladder unjury were excluded. After the reconstruction,
urinary catheter was placed for 24 hours. Then, after six hours, catheter was
removed and residual urine was measured. Urinary retention was defined as
residual urine more than 100 ml.
Results: Of 200 subjects recruited, 59 (29.5%) had POUR. There were no
association between age, body mass index, degree of uterine POPe, degree of
cystocele, urinary tract infectionand POUR. Duration of surgery > 130 minute and
Total vagina hysterectomy +anterior colporraphy + colpoperineorraphy +
sacrospinous fixation procedure and duration of surgery > 130 minute were
associated with POUR (RR 3.66, 2.91-4.60 95% CI, p<0.001 and 1.66 , 072.5995%CI,
p=0.02;
respectively)
Conclusion: POUR incidence after POP surgery was quite high. Type of the
procedure and duration of surgery were associated with POUR.
"
Fakultas Kedokteran Universitas Indonesia, 2015
SP-PDF
UI - Tugas Akhir  Universitas Indonesia Library
cover
Dwi Norma Fitri Anik
"Tumor payudara biasanya merupakan tumor jinak, akan tetapi tumor jinak ini dapat berubah menjadi keganasan (kanker payudara). Tumor payudara biasanya timbul pada usia di bawah 30 tahun (usia produktif). Oleh karena itu perlu adanya deteksi dini, SADARI (Pemeriksaan Payudara Sendiri) terhadap tumor payudara ini.
Penelitian ini bertujuan untuk mengidentifikasi adanya hubungan antara tingkat pengetahuan individu tentang tumor payudara dan SADARI terhadap tingkat motivasi yang mereka miliki untuk melakukan SADARI. Desain penelitian ini adalah deskripsi korelasi.
Penelitian ini dilakukan pada dua kelompok responden yaitu mahasiswi kelompok fakultas kesehatan dan mahasiswi kelompok fakuItas non kesehatan. Data primer diperoleh dari 106 responden melalui kuisioner.
Penelitian ini menggunakan uji Chi Square untuk mengetahui adanya hubungan antara tingkat pengetahuan dengan tingkat motivasi dan tingkat kemaknaan yang digunakan adatah 5% (α = 0,05).
Hasil penelitian pada kelompok fakultas kesehatan diperoleh nilai p Value = 0,049, yang berarti ada hubungan yang bermakna antara tingkat pengetahuan dengan tingkat motivasi. Namun, pada kelompok fakultas non kesehatan diperoleh hasil yang bertolak belakang dimana nilai p Value = 0,696, yang berarti tidak ada hubungan yang bermakna antara tingkat pengetahuan dengan tingkat motivasi."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2007
TA5561
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