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"Sikap masyarakat berdampak pada segala aspek kehidupan ODHA termasuk status kesehatannya. Penelitian ini bertujuan mengeksplorasi secara mendalam tentang sikap masyarakat pada ODHA. Studi fenomenologi dengan wawancara mendalam dan catatan lapangan peneliti terhadap 8 partisipan yang terjaring berdasarkan tekhnik purposive sampling. Hasil tematik analisis ditemukan 5 tema yaitu sikap masyarakat pada ODHA, pengetahuan dan persepsi tentang penyakit HIV/AIDS, makna ajaran agama, pandangan budaya, dan dukungan serta harapan masyarakat. Pengaruh tokoh masyarakat, ajaran agama, tradisi dan rasa kebersamaan berpengaruh terhadap pembentukan sikap masyarakat. Diperlukan dukungan terhadap peran aktif masyarakat khususnya pemberian informasi, penataan sistem penanggulangan, serta kebijakan untuk masyarakat miskin dan terlantar.

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Communities can be negative or positive to people living with HIV/AIDS (PLWHA) who both have an impact on all aspects of the lives of PLWHA, including their health status. People?s attitude were believed to be formed by the process and the effect of various things. This study explored public attitudes to PLWHA. The design used is a phenomenological study. Eight participants were selected by purposive sampling and interviewed. Data collection techniques performed by in-depth interviews and field notes. Data were analyzed using qualitative content analysis with Collaizi approach.

The findings reveal five main themes associated with a positive attitude and community support to PLWHA. Religion, tradition and social cohesion in the rural area influence the formation of positive attitude of the society. Communities have some problems during helping PLWHA to access health services. Health workers and government are expected to support the active participation of society, especially the provision of comprehensive information about HIV / AIDS issues, structuring prevention systems, as well as policies for the poor and neglected."

"Stigma terhadap ODHA telah menjadi masalah global yang epideminya selalu menyertai epidemi HIV dan AIDS. Penelitian ini bertujuan untuk mengetahui hubungan antara faktor internal dan eksternal dengan stigma terhadap ODHA pada pelajar SMA di Surabaya Selatan melalui pendekatan kuantitatif menggunakan data primer pada 785 responden di 11 SMA pada bulan Maret-Mei 2015. Hasil penelitian menunjukkan bahwa 53,2% pelajar memiliki stigma terhadap HIV&AIDS. Faktor paling dominan yang berhubungan stigma terhadap HIV&AIDS adalah pengaruh orang tua (p=0,0001; OR=6,05; 95% CI= 4,077-8,978) yang berarti pelajar yang terpengaruh sikap negatif orang tuanya akan berpeluang melakukan stigma 6,05 kali lebih besar dibandingkan yang tidak terpengaruh setelah dikontrol oleh pengetahuan, keterlibatan program, pengaruh teman sebaya, dan pengaruh guru. Kesimpulannya adalah pelajar yang memiliki pengetahuan rendah, tidak terlibat program, dan terpengaruh sikap teman sebayanya, guru di sekolah, dan orang tua cenderung akan melakukan stigma. Saran dari penelitian ini adalah dengan memaksimalkan peran orang tua, guru, dan teman sebaya dalam mengurangi stigma serta dan optimalisasi program HIV&AIDS berbasis sekolah.

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Stigma toward PWHA has been being one of global problem which it’s epidemic always near with epidemic of HIV and AIDS. This study is aimed to explore relationship between internal factors and external factors with stigma towards PWHA among students of Senior High School in South Surabaya through quantitative approach using primary data to 785 respondents in 11 senior high schools.

The results of this study shows that 53,2% students have stigma towards PWHA. The main factor that significantly related to stigma is influence of parents (p=0,0001; OR=6,05; 95% CI= 4,077-8,978). It means that students who was influenced by parents’ negative attitude, will have stigma toward PWHA 6,05 more than students who was not influenced.

Based on this study can be concluded that students whose low knowledge, never involve in HIV&AIDS program, influenced by their peer, teachers, and parents’ negative attitudes will have stigma toward PWHA. From the results it is expected the participation of the government to enhance the role of parents, peer group, and teachers to reduce stigma and also increase a school based program for HIV&AIDS."

"Jumlah kasus AIDS di Indonesia semakin meningkat, sampai periode Juni 2013 sebesar 43.667 kasus. ABK merupakan mobile migrant population yang memiliki perilaku seksual berisiko HIV/AIDS. Penelitian ini bertujuan mengetahui gambaran faktor-faktor yang berhubungan dengan perilaku seksual berisiko terkait HIV/AIDS pada ABK di Poliklinik KKP Kelas I Tanjung Priok. Penelitian ini merupakan penelitian observasional dengan desain penelitian yaitu cross-sectional. Populasi dalam penelitian ini adalah seluruh ABK yang melakukan kegiatan Medical Check Up (MCU) di poliklinik KKP Tanjung Priok. Sampel dalam penelitian ini adalah sebagian ABK yang melakukan kegiatan MCU dengan kriteria inklusi berjenis kelamin laki-laki, masa kerja minimal 3 bulan, WNI, dan menandatangani informed consent. Hasil penelitian menunjukkan 30,7% ABK memiliki perilaku seksual berisiko terkait HIV/AIDS. Karakteristik ABK terbanyak pada umur >30 tahun (56,7%), menikah (59,3%), pendidikan terakhir SMP keatas (78,7%), pulang ke daerah asal kurang dari 9 bulan sekali (78,7%), lama berlabuh ≤ 3 hari (59,3%), usia seks pertama >21 tahun (51,3%), tingkat pengetahuan kurang (53,3%), sikap negatif (54,7%), dan kurang terpapar informasi HIV/AIDS (56,7%). Faktor-faktor yang secara statistik memiliki hubungan dengan perilaku seksual berisiko adalah status pernikahan, pendidikan, frekuensi pulang ke daerah asal, lama berlabuh, usia seks pertama, pengetahuan, sikap dan keterpaparan media informasi. Sehingga perlu diberikan KIE mengenai HIV/AIDS dan penggunaaan kondom yang berkesinambungan serta penyediaan ATM kondom.

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The number of AIDS cases in Indonesia has increased, until the period of June 2013 amounted to 43.667 cases. The crew of ship is a mobile migrant population who have HIV/AIDS-risk sexual behaviors. This research aims to have description of the factors correlation with risk sexual behavior related to HIV/AIDS in the crew at the Polyclinic of Port Health Office Class I of Tanjung Priok. This research is an observational research using cross-sectional design study. Research population was entire the crew that have Medical Check Up (MCU) in the Polyclinic of Port Health Office Class I of Tanjung Priok. Research sample was partially of the crew that have Medical Check Up (MCU) with inclusion criteria male, work period at least 3 months, Indonesian, and signed informed consent.

The result showed 30,7% of the crew have HIV/AIDS-risk sexual behavior. Most of the crew characteristic are above 30 years old (56,7%), get married (59,3%), educational grade over junior high school (78,7%), back to their hometown less than once in 9 months (78,7%), longer anchore less than 3 days (59,3%), age of first sex in over 21 years old (51,3%), level of knowledge low (53,3%), negative demeanor (54,7%), and less exposure to HIV/AIDS information (56,7%). The factors that are statistically have correlation with risk sexual behavior was marital status, education, frequency back to their hometown, longer anchored, age of first sex, knowledge, attitudes and media exposure information. So that needs to be given information, education and communication about HIV/AIDS and sustainable use of condoms and provision of condoms ATM."

"[Waria yang merupakan salah satu populasi kunci dalam peningkatan HIV/AIDS, di Kota Kendal diperkirakan berjumlah lebih dari 400 orang. Dari seluruh kasus HIV/AIDS yang ada di Kendal waria menduduki urutan kelima. Penelitian ini bertujuan untuk memperoleh gambaran mendalam tentang pengalaman hidup waria dengan HIV/AIDS. Penelitian ini menerapkan desain penelitian deskriptif fenomenologi dengan wawancara mendalam. Sebelas partisipan diperoleh denganteknik purposive sampling. Dari hasil penelitian ini teridentifikasi 7 tema yaitu 1) Mengenali identitas diri sebagi waria, 2) Preferensi seksual terhadap laki-laki, 3) Persepsi waria terhadap sumber penularan HIV/AIDS, 4) Arti kehidupan bagi waria dengan HIV/AIDS, 5) Mengalami diskriminasi, 6) Bentuk dukungan waria dengan HIV/AIDS, 7) Hambatan dalam mengakses pelayanan kesehatan. Kesimpulan: seluruh waria menyadari identitas diri sebagai waria, dan merekamemahami pekerjaan dan perilaku seks beresiko menjadi sumber penularan HIV/AIDS. Sebagian waria mengalami kesulitan dalam mengakses layanan kesehatan akibat adanya diskriminasi;Transgenders is one of the key populations in the increasing in HIV / AIDS case,is estimated more than 400 people in the city of Kendal. The cases of transgender with HIV in Kendal is ranked on the top five. This study aims to gain a deeper understanding of transgender life experiences with HIV / AIDS. This research applies research design of descriptive phenomenology with depth interview. Eleven participants were recruited by purposive sampling technique. From the results of this study identified seven themes: 1) Recognize identity as a transgender, 2) sexual preference to males, 3) Perception transgenders againstthe source of transmission of HIV / AIDS, 4) The meaning of life for transgenders with HIV / AIDS, 5) Experience discrimination, 6) The support transgenders with HIV / AIDS, 7) Barriers in accessing health services. Conclusion: the entire transgender realize identity as transgender, and they understand the work and unsafe sexual behavior becomes a source of transmission of HIV / AIDS. Most transgenders have difficulty in accessing health services due to discrimination;Transgenders is one of the key populations in the increasing in HIV / AIDS case,is estimated more than 400 people in the city of Kendal. The cases of transgenderwith HIV in Kendal is ranked on the top five. This study aims to gain a deeperunderstanding of transgender life experiences with HIV / AIDS. This researchapplies research design of descriptive phenomenology with depth interview.Eleven participants were recruited by purposive sampling technique. From theresults of this study identified seven themes: 1) Recognize identity as atransgender, 2) sexual preference to males, 3) Perception transgenders againstthe source of transmission of HIV / AIDS, 4) The meaning of life for transgenderswith HIV / AIDS, 5) Experience discrimination, 6) The support transgenders withHIV / AIDS, 7) Barriers in accessing health services. Conclusion: the entiretransgender realize identity as transgender, and they understand the work andunsafe sexual behavior becomes a source of transmission of HIV / AIDS. Mosttransgenders have difficulty in accessing health services due to discrimination, Transgenders is one of the key populations in the increasing in HIV / AIDS case,is estimated more than 400 people in the city of Kendal. The cases of transgenderwith HIV in Kendal is ranked on the top five. This study aims to gain a deeperunderstanding of transgender life experiences with HIV / AIDS. This researchapplies research design of descriptive phenomenology with depth interview.Eleven participants were recruited by purposive sampling technique. From theresults of this study identified seven themes: 1) Recognize identity as atransgender, 2) sexual preference to males, 3) Perception transgenders againstthe source of transmission of HIV / AIDS, 4) The meaning of life for transgenderswith HIV / AIDS, 5) Experience discrimination, 6) The support transgenders withHIV / AIDS, 7) Barriers in accessing health services. Conclusion: the entiretransgender realize identity as transgender, and they understand the work andunsafe sexual behavior becomes a source of transmission of HIV / AIDS. Mosttransgenders have difficulty in accessing health services due to discrimination]"

"Latar belakang. Infeksi HIV dapat memicu inflamasi kronik dan reaktifasi CMV yang dan dapat mempengaruhi limfosit T. Gambaran seperti ini juga ditemukan pada usia lanjut dan berhubungan dengan penyakit degeneratif termasuk gangguan kognitif. Penelitian ini bertujuan untuk mengetahui pengaruh CMV dan limfosit T terhadap fungsi kognitif pada pasien HIV usia muda.Metode. JakCCANDO JAKarta CMV and Candida in HIV patients on ART, evaluation in CArdiology, Neurocognitive, Dentistry and Ophthalmology study, merupakan studi prospektif yang dilakukan di RSUPN. dr. Cipto Mangunkusumo. Studi ini melibatkan 80 pasien HIV 19-44 tahun yang belum pernah mendapat terapi antiretroviral ARV dengan limfosit T CD4

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Background. HIV can trigger chronic inflammation and CMV reactivation that affect T cell. These feature is also found in old age population and associated with degenerative disease including cognitive impairment. In this study we investigated the effects of CMV and T cells on cognitive function of younger HIV patients.Methods. JakCCANDO JAKarta CMV and Candida in HIV patients on ART, evaluation in CArdiology, Neurocognitive, Dentistry and Ophthalmology is a prospective study of patients at Cipto Mangunkusumo hospital. This study involved 80 HIV antiretroviral therapy ART naive patients 19 44 years with baseline CD4 T cell counts "

"Infeksi HIV dan penyakit AIDS saat ini telah menjadi masalah kesehatan global. Sejak awal abad ke 21 peningkatan jumlah kasus semakin mencemaskan di Indonesia. Penyebaran infeksi HIV biasanya terjadi pada perilaku seksual, tetapi beberapa tahun belakangan ini resiko penularan lebih banyak terjadi pada pengguna narkoba suntik.Penelitian ini menggunakan desain studi kohort retrospektif dengan 164 sampel dan dilakukan selama juli-september 2012 yang bertujuan untuk mengetahui hubungan antara cara penularan terhadap ketahanan hidup 9 tahun pasien HIV/AIDS di RS Kanker Dharmais Jakarta Tahun 2003-2011 setelah dikontrol oleh variabel lain, dengan faktor confounding yaitu jumlah CD4, infeksi oportunistik, jenis kelamin, usia, status pernikahan, jenis pekerjaan, tingkat pendidikan dan daerah tempat tinggal. Data penelitian diperoleh melalui data rekam medis RS. Data dianalisis dengan menggunakan analisis survival metode kaplan meier dan dilanjutkan dengan analisis multivariat.Hasil penelitian menunjukkan bahwa probabilitas kumulatif ketahanan hidup secara umum pada pasien HIV/AIDS cukup baik. Terdapat hubungan yang signifikan antara kadar CD4 terhadap ketahanan hidup (nilai p=0,03) dan infeksi oportunistik terhadap ketahanan hidup (nilai p=0,00. Faktor infeksi oportunistik dan jumlah CD4 memiliki hubungan dengan cara penularan untuk mempengaruhi ketahanan hidup 9 tahun pasien HIV/AIDS dan terbukti sebagai faktor confounding. Sedangkan faktor counfounding lain tidak menunjukkan adanya hubungan terhadap ketahanan hidup 9 tahun pasien HIV/AIDS.Hal yang disarankan adalah menekankan penatalaksanaan yang lebih intensif terhadap pencegahan infeksi oportunistik pada pasien yang sudah positif HIV.

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HIV and AIDS infection has been a pandemic health problem. Since the beginning of 21 century, case increasing in Indonesia has so disquiet. Infection transmission of HIV commonly happen to sexual activity, but the risk of transmission in drug user become more increase recently years.

This research use cohort retrospective design with 164 samples as long july until novemver 2012 which have purpose for knowing the relationship between transmission way to 9 years survival of HIV/AIDS patient at Dharmais Cancer Hospital, Jakarta 2003-2011 after adjustment with other variables. And also will discuss about CD4, opportunistic infection, other treatment history, sex, age, marriage state, type of occupations, education level, and domicile. Research data get from hospital medical record. Analized data use Kaplan meier survival analysis until multivariate test.

Research result show that survival cumulative probability of HIV/AIDS patients in generally is good. And also, there is a significant relation between CD4 to survival (Pvalue =0.03) and opportunistic infection to survival (Pvalue = 0.001). Opportunistic infection and CD4 proved as confounding factor between transmission way to survival. While, the other confounding factors haven’t significant relationship to 9 years survival of HIV/AIDS patients.

Recommended suggestion is to accentuating management for opportunistic infection prevention."

"Di Indonesia, kasus HIV/AIDS pada anak dari tahun 2010 sampai 2016 cenderung mengalami peningkatan. Salah satu penyakit penyerta yang sering muncul atau yang disebut dengan infeksi oportunistik pada klien dengan HIV/AIDS yaitu diare. Sampai dengan 60 dari orang yang hidup dengan HIV melaporkan diare. Diare adalah penyebab utama morbiditas dan mortalitas pada bayi dan anak-anak dan terutama mereka yang terinfeksi HIV. Salah satu intevensi keperawatan yang dapat dilakukan untuk mengurangi frekuensi BAB yaitu dengan terapi pijat yang merupakan salah sati terapi keperawatan komplementer. Terapi pijat dilakukan pada seluruh tubuh sebanyak dua hari dalam sehari selama tiga hari berturut-turut. Setelah dilakukan intervensi tersebut, tampak terjadi penurunan frekuensi BAB cair pada anak dengan diare persisten.

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In Indonesia, HIV AIDS cases in children from 2010 to 2016 tend to increase. One of common comorbid illness or so called opportunistic infection in clients with HIV AIDS is diarrhea. Up to 60 of people living with HIV report diarrhea. Diarrhea is a major cause of morbidity and mortality in infants and children, especially those who are HIV infected. One of the nursing intervention that can be done to reduce the frequency of diarrhea with massage therapy that one of complementary nursing therapy. Massage therapy is performed on the whole body twice a day for three consecutive days. After the intervention, there appears to be a decrease in frequency of diarrhea in children with persistent diarrhea."

"[ABSTRAKData dari Komisi Penanggulangan AIDS dan Dinas Kesehatan Surakartamenunjukkan bahwa pada tahun 2015 jumlah total kasus HIV/AIDS mencapai1.356 kasus, dimana terjadi kenaikan sebanyak 172 kasus dari tahun 2013. Tujuanpenelitian ini adalah untuk mengetahui pengalaman ODHA sebagai tenagavolunteer peer group support ODHA. Desain penelitian menggunakan metodekualitatif fenomenologi. Teknik pengambilan sampel dengan purposive sampling.Penelitian ini menggunakan 13 partisipan pada Kelompok Dukungan SebayaSolo. Hasil penelitian ini menghasilkan 5 (lima ). Tema tersebut adalah penilaianpositif terhadap diri, sumber motivasi volunteer, tantangan menjadi volunteer,upaya volunteer dalam meningkatkan kualitas hidup dan harapan sebagaivolunteer peer group support ODHA. Kesimpulan : Bekerja sebagai volunteermempengaruhi kehidupan ODHA. Perasaan dihargai, diterima dan bermanfaatbagi sesama dapat meningkatkan kualitas kehidupan ODHA. Diharapkan adanyapemberdayaan terhadap peer support dalam membantu perawatan ODHA.

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ABSTRACTThe National AIDS Commission and Surakarta Health Office show that in 2015the total of HIV / AIDS cases reached 1356 cases, where there is an increase of172 cases from 2013. The number of cases of HIV / AIDS has increased everyyear. The purpose of this study was to determine the experience of people livingwith HIV as a volunteer peer group support people living with HIV. Researchdesign using qualitative methods phenomenology. The sampling technique usingpurposive sampling. This study used 13 participants member of PLWHA peergroup in Solo. Five themes emerge in this study.. The theme are self positivevalue, source of motivation volunteer, volunteer challenges, effort to imcreasequality of life and expectations as volunteer peer group support PLWHA.Conclusions: Working as a volunteer affect the lives of people living with HIV.Feeling valued, accepted and useful for others can improve the quality of life ofpeople living with HIV. Expected for the empowerment of the peer support incaring PLWHA., The National AIDS Commission and Surakarta Health Office show that in 2015the total of HIV / AIDS cases reached 1356 cases, where there is an increase of172 cases from 2013. The number of cases of HIV / AIDS has increased everyyear. The purpose of this study was to determine the experience of people livingwith HIV as a volunteer peer group support people living with HIV. Researchdesign using qualitative methods phenomenology. The sampling technique usingpurposive sampling. This study used 13 participants member of PLWHA peergroup in Solo. Five themes emerge in this study.. The theme are self positivevalue, source of motivation volunteer, volunteer challenges, effort to imcreasequality of life and expectations as volunteer peer group support PLWHA.Conclusions: Working as a volunteer affect the lives of people living with HIV.Feeling valued, accepted and useful for others can improve the quality of life ofpeople living with HIV. Expected for the empowerment of the peer support incaring PLWHA.]"

"Stigma dan sikap diskriminatif terhadap ODHA merupakan sikap negatif masyarakat yang bersifat merendahkan dan menghambat kehidupan ODHA. Diperlukan pengurangan stigma dan sikap diskriminatif di masyarakat agar pencegahan dan pengendalian HIV/AIDS dapat berjalan optimal. Penelitian ini bertujuan untuk mengidentifikasi faktor-faktor yang mempengaruhi pemberian stigma dan sikap diskriminatif terhadap ODHA pada masyarakat berstatus kawin dan hidup bersama. Pendekatan potong-lintang dilakukan dengan menggunakan data SDKI 2017 pada 34.950 responden. Nilai asosiasi pemberian stigma dan sikap diskriminatif menggunakan prevalence ratio (PR) dan 95% confidence interval (CI). Dari seluruh responden didapatkan 22.419 (64,1%) memiliki stigma dan sikap diskriminatif terhadap ODHA. Faktor-faktor yang memiliki hubungan dengan stigma dan sikap diskriminatif terhadap ODHA yaitu usia (POR: 1,08; 95% CI: 1,048 – 1,112), tingkat pendidikan (POR: 1,037; 95% CI: 1,004 – 1,07), pengetahuan komprehensif HIV/AIDS (POR: 1,26; 95% CI: 1,23 – 1,3), keterpaparan informasi HIV/AIDS (POR: 1,07; 95% CI: 1,04 – 1,1), pengaruh pasangan terkait HIV/AIDS (POR: 1,03; 95% CI: 1 – 1,06), dan pengaruh emosional terkait HIV/AIDS (POR: 1,5; 95% CI: 1,42 – 1,57). Dibutuhkan pendekatan komprehensif dari segala pihak untuk mengurangi stigma dan sikap diskriminatif terhadap ODHA berupa edukasi dan penyebaran informasi yang merata mengenai HIV/AIDS serta pemberdayaan bagi ODHA.

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Stigma and discriminatory attitude towards PLWHA is a negative attitude of society that degrading and inhibits life of PLWHA. It is necessary to reduce stigma and discriminatory attitude in community to run HIV/AIDS prevention and control optimally. This study aims to identify factors that influence stigma and discriminatory attitudes towards PLWHA among married society and living together. The cross-sectional approach was carried out using the IDHS 2017 data with 34,950 respondents. Association between stigma and discriminatory attitudes was estimated through the prevalence ratio (PR) and 95% confidence interval (CI). From all respondents, 22,419 (64.1%) have stigma and discriminatory attitude towards PLWHA. Factors associated with stigma and discriminatory attitudes towards PLWHA are age (POR: 1.08; 95% CI: 1.048 – 1.112), education level (POR: 1.03; 95% CI: 1.004 – 1.07), comprehensive knowledge of HIV/AIDS (POR: 1.26; 95% CI: 1.23 – 1.3), exposure to HIV/AIDS information (POR: 1.07; 95% CI: 1.04 – 1.1), partner influence related to HIV/AIDS (POR: 1.03; 95% CI: 1 – 1.06), and emotional influence related to HIV/AIDS (POR: 1.5; 95% CI: 1.42 – 1.57). There should be a comprehensive approach from all parties to reduce the stigma and discriminatory attitudes towards PLWHA such as educational and equitable information dissemination of HIV/AIDS and empowerment for PLWHA."

"Penyakit HIV/AIDS merupakan masalah kesehatan di Indonesia. Masalah yang berkembang adalah karena angka morbiditas dan mortalitas yang masih tinggi, disebabkan antara lain karena keterlambatan mendapatkan pengobatan Anti Retroviral (ARV). Di Indonesia pengobatan ARV umumnya dimulai bila jumlah sel CD4 < 200 sel/mm3 atau bila stadium klinis 3 atau 4. Informasi tentang pengaruh jumlah sel CD4 sebelum pengobatan ARV terhadap ketahanan hidup satu tahun pasien HIV/AIDS berdasarkan kelompok kategori <50 sel/mm3, 50-<200 sel/mm3 dan > 200 sel/mm3, saat ini belum tersedia di Indonesia. Untuk mengetahuinya, maka dilakukan penelitian ini. Desain penelitian kohort retrospektif, dilakukan pengamatan terhadap kematian pada populasi dinamis selama satu tahun (366 hari), dari Januari 2005 hingga Januari 2010. Subjek penelitian 158 pasien HIV/AIDS berusia > 15 tahun, naïve dan mendapat regimen ARV lini pertama di RSPI Prof.DR.Sulianti Saroso pada tahun 2005-2010. Prosedur analisis ketahanan hidup menggunakan metode Kaplan-Meier (product limit), analisis bivariat dengan Log rank test (Mantel cox) dan analisis multivariat dengan cox regression / cox proportional hazard model. Penelitian ini mendapatkan probabilitas ketahanan hidup keseluruhan satu tahun pasien HIV/AIDS dengan pengobatan regimen ARV lini pertama adalah 0,86 (CI 95% 0,79-0,91). Incident rate kematian (Hazard rate) kelompok jumlah sel CD4 <50 sel/mm3 adalah 8/10.000 orang hari (29/100 orang tahun), kelompok jumlah sel CD4 50-<200 sel/mm3 adalah 3/10.000 orang hari (11/100 orang tahun) dan kelompok jumlah sel CD4 > 200 sel/mm3 adalah 2/10.000 orang hari (7/100 orang tahun). Hazard Ratio(HR)-adjusted kelompok jumlah sel CD4 <50 sel/mm3 terhadap kelompok jumlah sel CD4 > 200 sel/mm3 adalah 3,4 (p= 0,058 ; CI 95% : 0,96-12,16), HR-adjusted kelompok jumlah sel CD4 50-<200 sel/mm3 terhadap kelompok jumlah CD4 > 200 sel/mm3 adalah 1,7 (p= 0,48 ; CI 95% : 0,4-7.04). HR-adjusted pasien dengan TB 3,57 kali terhadap pasien tanpa TB (p=0,015 ; CI 95% : 1,27-9,99). Jumlah sel CD4 sebelum pengobatan ARV tidak mempunyai pengaruh secara statistik terhadap ketahanan hidup satu tahun pasien HIV/AIDS yang mendapat regimen ARV lini pertama. Namun penelitian mendapatkan penyakit Tuberkulosis (TB) mempunyai pengaruh secara statistik terhadap ketahanan hidup satu tahun pasien HIV/AIDS yang mendapat regimen ARV lini pertama.

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HIV/AIDS disease is one of public health concerns in Indonesia. The growing issues related to high morbidity and mortality rate. This is due to such as lately initiated of Antiretroviral (ARV) therapy. In Indonesia ARV therapy is begun when the CD4 cell counts dropped below 200 cell/mm3 or if clinical stadium fall into 3rd or 4th. Nowadays in Indonesia, Information about the influenced of baseline CD4 cell count to one year survival among patient HIV/AIDS with first line ARV regimen therapy, base on strata <50 cell/mm3, 50- <200 cell/mm3 and > 200 cell/mm3 was not available, therefore this research will be conducted.

Study design was retrospective cohort, with one year (366 days) duration of observation to death, in dynamic population from January 2005 to January 2010. The subjects of study were 158 HIV/AIDS patients, with inclusion criteria: > 15 years old, naïve, and were treated by first line ARV regimen at RSPI Prof.DR. Sulianti Saroso in year 2005-2010. The procedures of survival analysis used Kaplan-Meier method (product limit), and Log rank test (Mantel cox) for bivariate analysis and cox regression / cox proportional hazard model for multivariat analysis.

The overall of one year survival probability in HIV/AIDS patients with first line ARV regimen therapy was 0,86 (CI 95% 0,79-0,91). Incident rate of death (Hazard rate) in CD4 <50 cell/mm3 group was 8/10.000 persons days (29/100 persons years), in CD4 50-<200 cell/mm3 group was 3/10.000 persons days (11/100 persons years) and in CD4 > 200 cell/mm3 group was 2/10.000 persons days (7/100 persons years).

The Hazard Ratio(HR)-adjusted CD4 <50 cell/mm3 patients compared to CD4 > 200 cell/mm3 patients was 3,4 (p= 0,058 ; CI 95% : 0,96-12,16), the HR-adjusted CD4 50-<200 cell/mm3 patients compared to CD4 > 200 cell/mm3 patients was 1,7 (p= 0,479 ; CI 95% : 0,4-7.04). HRadjusted tuberculosis patients was 3,57 time more risk to death than patients without tuberculosis (p=0,015 ; CI 95% : 1,27-9,99).

This study found that the baseline CD4 cell counts have not significant statistical associated to one year survival of HIV/AIDS patients with first line ARV regimen therapy, after has controlled to other independent variables. But this study found that tuberculosis has significant statistical association to one year survival of HIV/AIDS patients who received first line ARV regimen therapy."