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"Background: Dyspepsia is an important health problem from economic and quality of life point of view. However; to date, there has not been specific instrument of quality of life to evaluate patients with dyspepsia specially design in Indonesian language. The Nepean Dyspepsia Index (NDI) is a reliable and valid instrument regarding quality of life in patients with dyspepsia and had been validated in Australia, Germany, ltaly and Netherlands.Objective: To report translation of NDI in Indonesian language and validation in Indonesian patients with dyspepsia and also evaluate the possibility of its use in subjects who speak Indonesian language.Methods: NDI was translated into Indonesian language. The amount of 49 subjects with a clinical diagnosis of dyspepsia according to the inclusion and exclusion criteria were recruited. Collection of data included demographic data, physical and laboratory examination. All subjects were asked to complete translation of NDI. Reliability analysis was evaluated by a-Cronbach's and test-retest. Since dyspepsia has no gold standard, validity was evaluated rising factor analysis.Result: Reliability of the questionnaire was good, a-Cronbach's and interclass correlation coefficient were found to be > 0.70 respectively and Kaiser-Meyer-Olkin value was found to be > 0.64, suggesting that all items were appropriate to measure.Conclusion: translated NDI in Indonesian language can be used in dyspepsia, patients who understand Indonesian language."

"Oesofago-Gastro-Duodenoscopy (OGD) dilakukan pada pasien yang diterima melalui sistem "open acces " dan sistem biasa. Keluhan dapat berbeda pada pasien yang berumur < 45 tahun atau yang berumur > 45 tahun. Diagnosis rujukan, umur, gender dan faklor lingkungan dapat menimbulkan implikasi penting. Studi ini ditujukan untuk mempelajari profil pasien yang datang untuk OGD berdasarkan usia (< 45 tahun atau > 45 tahun) antara Januari 2004 - Desember 2004 yang dirujuk berdasarkan "open acces system" di wilayah sub-Himalaya, India Utara. Studi ini dilakukan di Indira Gandhi Medical College. Pasien dibagi dua kelompok: kelompok I usia < 45 tahun dan kelompok II usia > 45 tahun. Dari 1186 pasien, 451 (38%) adalah perempuan, 735 (62%) adalah laki-laki. Enam ratus enambelas pasien (52%) berusia < 45 tahun dan 570 (48%) berusia > 45 tahun. Dari kelompok /, 431 (70%) menunjukkan gambaran endoskopi yang normal dan 185 (30%) menunjukkan kelainan. Pada kelompok II 302 (53%) menunjukkan gambaran endoskopi yang normal, dan 268 (47%) memperlihatkan kelainan pada endoskopi. Ulkus gaster dan masa lebih sering terlihat pada kelompok > 45 tahun. "Gastro-esophageal reflex disease" (GERD) lebih sering pada usia muda. Gejala subjektif sama pada kedua kelompok. Disimpulkan bahwa untuk gejala yang sama, kelainan OGD lebih sering pada kelompok usia > 45 tahun. Hasil positif meningkat dari 30% menjadi 47% antara usia < 45 dan > 45 tahun. Disimpulkan bahwa semua pasien usia > 45 Tahun perlu dirujuk untuk endoskopi pada kali pertama kelainan gastrointestinal atau adanya alarm simtom. (MedJ Indones 2006; 15:90-3).

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The Oesophago-Gastro-Duodenoscopy (OGD) is done in patients received by either open access system or the conventional system. The presenting complaints and OGD findings may differ among patients with age < 45 yrs and those who are more than 45 yrs old. The referral diagnosis, age, sex, and environmental factors have important implications on the chances of finding and objective abnormality on endoscopy in a patient. This study was aimed to evaluate to evaluate the profile of ! 186 patients divided into younger (<45 yrs) and older age (45 or > 45 yrs) groups presenting for oesophago gastroduodenoscopy through open access referral system in sub-Himalayan region of North India. This is a retrospective study carried out on patients who underwent the OGD from Jan, 2004-Dec, 2004. The study was conducted in Indira Gandhi Medical College situated at a moderate altitude in North India. All patients presenting in Medical College during the study period for OGD were taken into study. The patients were divided into two groups based on age; less than 45 yrs and 45 yrs or more than 45 yrs. Their presenting complaint, age, sex, and OGD findings were recorded. The profile was compared between the two groups. A total of 7186 patients underwent OGD; the females were 451(38%) and males were 735(62%); 616(52%) were < 45 yrs old and 570(48%) of the patients were 45 yrs or older. In the group I 431(70%) had a normal endoscopy and 185(30%) showed abnormal endoscopic findings. In group II 302(53%) had a normal endoscopy, and 268(47%) had abnormal findings on endoscopy. Gastric ulcers, mass lesion/new growth were more common in elderly group, Gastro-esophageal reflux disease (GERD) was more common in younger group. The presenting complaints were similar in both groups. It is concluded that for the same presenting diagnosis the yield of OGD was more in patients > 45 yrs old. The positivity rate increased from 30% in < 45 yrs to 47% in the elderly cohort. So, all people >45 yrs should go for endoscopy at the first hint of upper Gl pathology, or appearance of alarm symptoms. (MedJ Indones 2006; 15:90-3)."

"Dyspepsia is one of numerous general complaints, which is commonly encountered by doctors of various disciplines. In daily practice, the complaint is not only limited for gastroenterologists. Knowledge on pathophysiology of dyspepsia have been developing continuously since a scientific investigation has been started in 1980s, which considers Helicobacter pylori as one of key factor in managing dyspepsia, either it is associated with ulcer or non-ulcer. The management of dyspepsia cannot be separated from the management of H. pylori and there is an additional new knowledge associated with definition, pathophysiology, diagnosis and treatment of both dyspepsia and H. pylori infection.

This consensus document on the management of dyspepsia and H. pylori infection in Indonesia has been developed using the evidence-based medicine principles; therefore, it can be used as a reference for doctors in dealing with dyspepsia and H. pylori infection cases in their daily practice. It is expected that with the new consensus, doctors can provide greater service to their patients who have dyspepsia and H. pylori infection."

"Dispepsia merupakan sindrom penyakit pada regio gastroduodenal yang berpengaruh besar terhadap kualitas hidup penderitanya baik secara fisik maupun mental. Berbagai terapi farmakologis telah dikembangkan, namun efektivitasnya masih belum maksimal. Akupunktur merupakan salah satu modalitas terapi yang telah terbukti efektif dalam mengatasi gejala-gejala dispepsia. Elektroakupunktur (EA) pada titik ST 36 Zusanli merupakan metode perangsangan dan titik akupunktur yang paling sering digunakan dalam penelitian untuk mengatasi masalah lambung melalui mekanisme yang melibatkan nitrit oksida (NO). Penelitian ini bertujuan untuk mengetahui efektivitas metode terapi elektroakupunktur dibandingkan dengan akupunktur manual pada ST 36 Zusanli terhadap peningkatan kadar NO serum pada penderita dispepsia. Uji klinis acak tersamar ganda dengan pembanding dilakukan terhadap 40 pasien dispepsia yang dibagi ke dalam kelompok elektroakupunktur (EA) dan kelompok akupunktur manual (AM). Hasil penelitian menunjukkan terdapat perbedaan bermakna rerata peningkatan kadar NO serum pada kelompok elektroakupunktur dibandingkan dengan kelompok akupunktur manual (p = 0,026). Kesimpulan penelitian ini yaitu tindakan elektroakupunktur pada ST 36 Zusanli lebihefektif meningkatkan kadar NO serum dibandingkan tindakan akupunktur manual pada pasien dispepsia (p < 0,05).

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Dyspepsia is a syndrome in gastroduodenal region which affect the quality of life ofpatients both physically and mentally Various pharmacological therapies have beendeveloped but its effectiveness is unsatisfying Acupuncture is a modality that hasbeen proven effective in addressing the symptoms of dyspepsia Electroacupuncture EA at ST 36 Zusanli is the method of stimulation and acupuncture points whichmost frequently used in research to overcome the problem of the stomach through amechanism involving nitric oxide NO

The aim of this study was to determine theeffectiveness of electroacupuncture treatment method compared to manualacupuncture at ST 36 Zusanli to increase serum levels of NO in patients withdyspepsia A double blind randomized controlled trial involved 40 patients withdyspepsia randomly allocated into groups of electroacupuncture EA and manualacupuncture MA

The results showed there were significant differences in themean serum levels of NO in the EA group compared to the MA group p 0 026 The results suggested that electroacupuncture at ST 36 Zusanli is more effectivethan manual acupuncture in increasing the serum levels of NO in patients withdyspepsia p 0 05"

"Latar belakang: Dispepsia merupakan gangguan kesehatan yang sering ditemuierologi dan urin (RAPIRUN) dibandingkan dengan UBT sebagai baku emas dalam mengetahui infeksi H. pylori. Penelitian dilakukan pada pasien rawat jalan Puskesmas Kecamatan Koja Kotamadya Jakarta Utara. Yang dinilai adalah sensitivitas, spesivisitas, positive predictive value (PPV), negative predictive value (NPV) tes tersebut. Tujuan: Mengetahui akurasi diagnostik pemeriksaan non-invasif (serologi dan urin) dibandingkan dengan UBT (urea breath test) sebagai baku emas untuk mendeteksi infeksi H. pylori pada pasien dengan sindroma dispepsia. Metode: Penelitian yang digunakan adalah studi potong lintang untuk mengetahui akurasi pemeriksaan non-invasif yaitu s H. pylori menunjukkan hasil positif pada 36,5% subyek, sedangkan pada pemeriksaan serologi (Mataram, Biomedika) didapatkan hasil positif sebanyak 32,4%. Pemeriksaan RAPIRUN (Rapid Urine Test, Otsuka) menunjukkan hasil positif pada 24,3% subyek. Pada serologi didapatkan sensitivitas 74%, spesifitas 91%, PPV 83%, NPV 86%. Sedangkan pada RAPIRUN didapatkan sensitivitas 63%, spesifitas 98%, PPV 94%, NPV 82%. Hasil: Selama kurun waktu April 2015 sampai Juni 2015, 74 subyek, dengan mayoritas perempuan (82,4%), dengan rerata umur 45,05 tahun menjalani pemeriksaan non-invasif. Pemeriksaan UBT sebagai baku emas diagnosis infeksi di pelayanan kesehatan. Infeksi Helicobacter pylori adalah salah satu penyebab dispepsia. Diagnosis infeksi H.pylori dapat dilakukan melalui pemeriksaan invasif dan non invasif. Pemeriksaan non invasif lebih mampu laksana, murah dan memiliki risiko yang lebih sedikit. Simpulan: RAPIRUN lebih unggul dalam hal spesifisitas dibanding serologi.

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Background: Dyspepsia is the common problem in the population. The main etiology of dyspepsia is Helicobacter pylori infection. The diagnosis of H. pylori infection is based on invasive examination and non-invasive examination. The non-invasive examination could be easier to do and have less risk than invasive examination.

Objective: To evaluate the diagnostic accuracy of the non-invasive test (serology and RAPIRUN) compared to UBT as gold standard examination to detect H. pylori infection in patients with dyspepsia syndrome.

Methods: A cross-sectional study for diagnostic H. pylori by using serology and Rapid Urine test (RAPIRUN) is conducted to evaluate the diagnostic accuracy of non-invasive test compared to UBT as gold standard examination in patients with dyspepsia syndrome. This study was conducted at outpatient Community Health Center in Koja District North Jakarta from middle April 2015 until Middle June 2015. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) were used to evaluate the diagnostic accuracy.

Results: From mid-April 2015 to Mid-June 2015, 74 subjects, with the majority of patients was female (82.4%), and the mean of age was 45.05 years old, had undergone non-invasive test The UBT test as the gold standard examination for H. pylori infection showed positive result in 36.5% patients while the serology test resulting positive in 32.4%. The RAPIRUN test resulting positive in 32.4% patients. The sensitivity of serology test was 74%, specificity 91%, PPV 83%, NPV 86%, meanwhile the RAPIRUN test was resulting as sensitivity 63%, specificity 98%, PPV 94%, NPV 82%.

Conclusion: RAPIRUN has a high diagnostic value for H. pylori in specificity than serology."

"ABSTRAKLatar belakang: Sindrom dispepsia fungsional merupakan gejala gastrointestinalyang bersifat kronis atau rekuren dan tidak dapat dijelaskan, karena abnormalitasbiokimia atau struktural pada evaluasi menggunakan pemeriksaan diagnostikstandar tidak menunjukkan adanya abnormalitas. Pada penelitian ini ingindiketahui apakah pekerja rumah sakit yang bekerja dengan sistem kerja gilirberhubungan dengan sindrom dispepsia fungsional dibandingkan dengan pekerjayang tidak bekerja secara gilir.Metode: Desain studi yang digunakan adalah komparatif potong lintang yangmembandingkan antara pekerja dengan sistem kerja gilir dengan pekerja bukandengan sistem gilir. Data yang digunakan adalah data primer (kuesioner danwawancara), dan data sekunder (rekam medis serta data kepegawaian). Subjekterdiri dari 218 pekerja (109 pekerja gilir dan 109 pekerja bukan gilir).Hasil penelitian: Prevalensi dispepsia fungsional pada pekerja rumah sakitJakarta adalah 42,2%. Pada analisis multivariat didapatkan bahwa kerja gilir(OR=2,22 (1,212-4,086) p=0,010), usia (OR=0,39 (0,209-0,752) p=0,005), polamakan (OR=1,90 (1,045-4,455) p=0,035), dan status perkawinan (OR=2,49(1,097-5,651) p=0,029) mempunyai hubungan bermakna dengan dispepsiafungsional.Pembahasan: Kerja gilir, usia, pola makan, dan status perkawinan merupakanfaktor risiko sindrom dispepsia fungsional. Usia dan jenis kelamin menjadi faktorprotektif. Usia menjadi faktor protektif karena adanya mekanisme adaptasidispepsia. Jenis kelamin sebagai faktor protektif mungkin disebabkan padaperempuan tingkat kesadaran terhadap kesehatan lebih tinggi yang menyebabkanangka mortalitas lebih kecil daripada laki-laki

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ABSTRACTBackground: Functional dyspepsia syndrome is a gastrointestinal symptoms thatare chronic or recurrent and can not be explained, because the biochemical orstructural abnormalities in the evaluation using standard diagnostic examinationshowed no abnormalities. In this study, we want to know whether the hospitalworkers who worked shift work system associated with the syndrome offunctional dyspepsia compared with workers who do not work in shifts.Method: The study design used was a comparative cross-sectional comparingbetween workers with shift work system to workers who work not with the shiftsystem. The data used are primary data using questionnaires and interviews, andsecondary data through medical records and employment data. Subjects consistedof 218 employees (109 workers with shift work and 109 workers without shiftwork).Results: The prevalence of functional dyspepsia at Jakarta hospital workers was42.2%. On multivariate analysis, it was found that shift work (Adj. OR=2.22(1.212-4.086) p=0.010), age (Adj. OR=0.39 (0.209-0.752) p=0.005), diet (Adj.OR=1.90 (1,045-4.455) p=0.035) and marital status (Adj. OR=2.49 (1.097-5.651)p=0.029) had a significant relationship with functional dyspepsia.Discussion: Shift work, age, diet, and marital status are risk factors syndromefunctional dyspepsia. Age and sex becomes a protective factor. Age becomes aprotective factor for their adaptation mechanism of dyspepsia. Gender as aprotective factor may be due to the level of awareness of women's health ishigher that causes of mortality rate is smaller than the male"

"In up to 80% of dyspepsia patients who consult a physician in the hospital, dyspepsia is considered to be functional dyspepsia. Although not associated with increased mortality, functional dyspepsia is a burden at both the community and national levels because it can cause physical, mental, and social ditress that can affect a patients quality of life. Health-related quality of life (HRQOL) is a multidimensional construct comprising at least three broad domains-physical, psychological, and social functioning-which can all be affected by a disease and its treatment. It is important to assess HRQOL in patients with functional dyspepsia to identify the effects of the disease and its treatment on patients. Both disease-specific and generic instruments can be used to assess HRQOL in patients with functional dyspepsia. Each instrument has it own advantages and limitations. The selection of instrument to assess HRQOL is determined by the study population, research questions, disease entities, and researcher preferences. The purpose of this article is to explain the concept of HRQOL and the use of HRQOL assessment in patients with functional dyspepsia."

"Dyspepsia merupakan kumpulan gejala yang berasal dari daerah lambung atau usus 12 jari. Mekanisme spesifik dari kompleks gejala yang terjadi belum sepenuhnya diketahui, namun prevalensi keluhan dyspepsia diperkirakan mencapai 30%. Clinical pathway adalah alat untuk membantu proses pelayanan kesehatan berbasis bukti. Karakteristik dari clinical pathway adalah clinical pathway dibuat berdasarkan tatalaksana umum, menjelaskan langkah-langkah yang dilakukan untuk melakukan suatu tindakan, dan menstandarisasi alur tindakan untuk suatu masalah khusus. Karena itu, clinical pathway dyspepsia dapat bermanfaat sebagai pedoman dasar dalam pengobatan dyspepsia, terutama pada instalasi gawat darurat karena prevalensi yang cukup tinggi dan kemungkinan adanya keterbatasan waktu atau tenaga pada instalasi gawat darurat. Laporan ini membahas clinical pathway dyspepsia yang diharapkan dapat membantu IGD RSUI dalam penanggulangan kasus darurat dyspepsia di masa depan.

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Dyspepsia is a group of symptoms that comes from the stomach or duodenal area. The specific mechanism of the symptom complex is not fully known, but the prevalence of dyspepsia is approximated to reach 30%. Clinical pathway is a tool to help the process of healthcare based on proof. The characteristic of clinical pathway is that it is made based on a common procedure, explains the steps needed to do an action, and standardized the flow of actions on a specific problem. This makes clinical pathway of dyspepsia to be useful as a basic guide on dyspepsia treatment, especially on the emergency unit because of the high prevalence and the possibility of limited time or power on emergency units. This report discusses the clinical pathway of dyspepsia that is hoped to help the emergency unit of Universitas Indonesia Hospital on the management of emergency cases of dyspepsia in the future."

"Prevalensi terjadinya Tuberkulosis (TB) paru meningkat seiring dengan peningkatan prevalensi pasien (Diabetes Melitus) DM. TB dapat menyebabkan intolerasi glukosa dan memperburuk kontrol glikemik pada penderita DM. Tujuan penelitian ini adalah menganalisa dan melakukan evaluasi terhadap masalah terkait obat serta memberikan reomendasi penyelesaian masalah untuk meningkatkan kualitas hidup pasien dengan DM, TB, dan dispepsia. Pemantauan Terapi Obat (PTO) dilakukan dengan mengumpulkan data pasien dari rekam medis kemudian menganalisis berdasarkan metode Hepler and Strand serta merekomendasikan penyelesaian masalah yang ditemukan. Berdasarkan hasil analisis, ditemukan bahwa terdapat indikasi yang tidak diterapi yaitu DM dan anemia mikrositik tanpa terapi pengobatan farmakologi. Berdasarkan hasil analisis pemantauan terapi obat pada pasien, dapat disimpulkan bahwa pengobatan yang diterima hampir seluruhnya tepat indikasi. Selain itu, tidak terdapat interaksi obat dari obat-obat yang diresepkan. Namun, ditemukan indikasi yang tidak diterapi yaitu mual serta diabetes yang hanya diberikan terapi non farmakologi dengan diet, akan tetapi gula darah pasien sudah terkontrol, serta indikasi anemia mikrositik tanpa terapi.

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The prevalence of pulmonary tuberculosis (TB) increases along with the increasing prevalence of DM (Diabetes Mellitus) patients. TB can cause glucose intolerance and worsen glycemic control in DM patients. The purpose of this study was to analyse and evaluate drug-related problems and provide recommendations for problem solving to improve the patients quality of life with DM, TB, and dyspepsia. Drug Therapy Monitoring (PTO) is carried out by collecting patient data from medical records, analysing it based on the Hepler and Strand methods, and recommending solutions to the problems found. Based on the results of the analysis, it was found that there were indications without therapy DM and microcytic anaemia without pharmacological treatment. Based on the results of the monitoring analysis of drug therapy in patients, it can be concluded that the treatment received was almost entirely indicated. In addition, there were no drug interactions with the prescribed drugs. However, indications were found that were not treated, namely nausea and diabetes, which were only given non-pharmacological therapy with diet, but the patient's blood sugar was controlled, as well as indications of microcytic anaemia without therapy"

"Latar belakangDispepsia fungsional merupakan kumpulan gejala GIT dengan berbagai faktor penyebab. Depresi merupakan salah satu faktor yang berperan panting pada penderita dispepsia fungsional. Depresi sering dijumpai pada penderita dispepsia fungsional dalam menghadapi kehidupannya dan sering terabaikan dalam penatalaksanaannya.Anggota TNI AD merupakan populasi pilihan dan diharapkan mempunyai ketahanan mental dan frsik yang lebih baik. Dalam menghadapi tugas dan kehidupannya, bagaimana peranan depresi pada anggota TNI AD yang menderita dispepsia fungsionalMetodologiSampel didapatkan secara konsekutif sebanyak 95 anggota TNI AD yang menderita dispepsia fungsional di RSPAD Gatot Soebroto, periode Oktober 2005 sampai Juli 2006 dan dilakukan wawancara terstruktur dengan instrumen SLID I untuk diagnosis gangguan depresi berdasarkan DSM IV.HasilPrevalensi depresi pada anggota TNI AD yang menderita dispepsia fungsional adalah sebesar 54,7 %. Faktor-faktor seperti umur (diatas 40 tahun), pangkat (Perwira), tempat tugas (di Staf, di daerah operasi militer, waktu tugas di daerah operasi militer), tempat tinggal (rumah sendiri) dan pemikahan menunjukkan kecenderungan mengalami depresi.SimpulanKejadian depresi pada anggota TNI AD yang menderita dispepsia fungsional tidak jauh berbeda dengan populasi umum.

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Background

Functional dyspepsia is a syndrome of GIT symptoms with multifactor etiologies. Depression is one of the important factors that influence on functional dyspepsia patient Depression is often found on functional Dyspepsia patient in facing their life event and is often ignored in the treatment.

The Indonesian army forces were selected population and are expected to have better mental and physical endurance. In facing the military duty and life event, how is the relation of depression in the army patient with functional dyspepsia.

Method

95 Samples were obtained consecutively from the army patient with functional dyspepsia in RSPAD Gatot Soebroto between October 2005 and July 2006 by using structured interview with SCID-1 instrument for the diagnosis of depression disorders according to DSM IV

Result

The prevalence of depression of Indonesian army with functional dyspepsia was 54.7%. Factor such as age (above 40 years), official rank, staff assignment, military operation and point of military operation time, living in own residence and the marriage are shown to have depression tendency.

Conclusion

The prevalence of depression of Indonesian army with functional dyspepsia was found to be almost equally comparable with general population."