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Hasil Pencarian

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Chairul Rijal
Abstrak :
ABSTRAK
Tujuan: untuk mengetahui prevalensi inkontinensia urin, sebaran tipe inkontinensia urin dan faktor-faktor risiko yang berhubungan pada wanita yang berusia diatas 50 tahun.

Metode: penelitian ini merupakan penelitian deskriptif dengan desain potong lintang. Sebanyak 278 wanita berusia diatas 50 tahun yang tinggal di panti werdha, telah dilakukan wawancara secara terpimpin menggunakan kuesioner Questionnaire for Urinary Incontinence Diagnosis (QUID) yang telah diterjemahkan dan divalidasi. Hasil prevalensi inkontinensia urin disajikan dalam bentuk proporsi/persentase, sedangkan hubungan antara faktor risiko dengan kejadian inkontinensia urin dianalisa dengan uji chi square atau uji Fisher bila syarat uji chi square tidak terpenuhi, dan juga dilakukan uji multivariat.

Hasil: dari 278 subyek penelitian, didapatkan sebanyak 95 orang (34,2%) menderita inkontinensia urin. Dengan sebaran tipenya adalah sebagai berikut: inkontinensia urin tipe campuran 67 orang (70,5%), inkontinensia urin tipe tekanan 17 orang (17,9%) dan inkontinensia urin tipe desakan 11 orang (11,6%). Indeks massa tubuh (IMT) berlebih dan obesitas tidak memiliki hubungan dengan kejadian inkontinensia urin (p> 0,05), mungkin pada penelitian ini jumlah subyek dengan IMT berlebih dan obesitas jumlahnya terlalu kecil. Sedangkan faktor-faktor risiko yang berhubungan dengan inkontinensia urin adalah: usia diatas 60 tahun (OR 7,79, p= 0,021), menopause >10 tahun (OR 5,08, p=0,004), dan multipara (OR 1,82, p=0,019). Pada saat dilakukan uji multivariat, faktor risiko usia diatas 60 tahun didapatkan menjadi tidak berhubungan dengan kejadian inkontinensia urin (p> 0,05). Hal ini disimpulkan bahwa faktor usia diatas 60 tahun bukan merupakan faktor tunggal akan terjadinya inkontinensia urin melainkan multifaktor.

Kesimpulan: penelitian ini mendapatkan angka prevalensi inkontinensia urin pada wanita yang tinggal di panti werdha adalah sebesar 34,2%. Sedangkan sebaran tipe inkontinensia urin adalah: inkontinensia urin tipe campuran 67 orang (70,5%), inkontinensia urin tipe tekanan 17 orang (17,9%) dan inkontinensia urin tipe desakan 11 orang (11,6%). Faktor-faktor risiko inkontinensia urin adalah: menopause >10 tahun dan multipara.
ABSTRACT
Aim: to identify the prevalence of urinary incontinence, the distribution of the type of urinary incontinence and and related risk factors in women older than 50 years.

Method: this is a descriptive study with cross sectional design. Two hundred and seventy eight women older than 50 years old living in nursing house were interviewed using the Questionnaire for Urinary Incontinence Diagnosis (QUID) that has been translated and validated previously. The prevalence result will be presented in the form of percentage; while the relationship between risk factors and the incidence or urinary incontinence will be analyzed using chi square test or Fisher’s exact test if the requirement for chi square test is not met, and multivariate analysis.

Result: Of 278 research subjects, we obtain 95 subjects (34,2%) suffering from urinary incontinence. And the distribution of the type is as follow: 67 subjects (70,5%) with mixed urinary incontinence, 17 (17,9%) with stress urinary incontinence and 11 subjects (11,6%) with urge incontinence. Overweight and obesity body mass index (BMI) are not related with the prevalence of urinary incontinence (p> 0,05), probably in this research the number of subjects with overweight and obesity is too small. While factors related to urinary incontinence are age older than 60 years (OR 7,79, p = 0,021), menopause ≥10 years (OR 5,08, p=0,004) and multiparity (OR 1,82, p = 0,019). When multivariate analysis was done, the risk factor age older than 60 years becomes not related to urinary incontinence (p>0,05). Thus it can be inferred that age older than 60 years is not a singular factor of urinary incontinence but rather a multifactor.

Conclusion: This study shows that the prevalence of urinary incontinence in women living in nursing home is 34,2%; while the distribution of the urinary incontinence is: 67 subjects (70,5%) with mixed urinary incontinence, 17 subjects with stress urinary incontinence (17,9%) and 11 subjects (11,6%) with urge urinary incontinence. Risk factors for urinary incontinence are: menopause ≥10 years and multiparity.
Depok: Fakultas Kedokteran Universitas Indonesia, 2013
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UI - Tesis Membership  Universitas Indonesia Library
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Rosiana Waicang
Abstrak :
Inkontinensia urin setelah operasi BPH adalah hilangnya kontrol terhadap buang air kecil karena salah satu katup yang mengontrol urin diangkat bersamaan dengan prostat, apabila katub ini diangkat kemungkinan terjadi kerusakan sraf dan otot sehingga menyebabkan inkontinensia setelah operasi prostat. Inkontinensia urin dapat menyebabkan masalah fisik, psikologis, sosial dan ekonomi sehingga mempengaruhi kualitas hidup. Penelitian ini bertujuan untuk mengidentifikasi faktor-faktor yang berhubungan dengan kejadian inkontinensia urin setelah operasi prostat. Penelitian ini menggunakan desain cross sectional, dengan pendekatan deskriptif korelatif, dan teknik consecutive sampling pada 90 responden. Hasil penelitian menunjukkan tidak terdapat hubungan signifikan antara Usia dengan kejadian inkontinensia urin (p-value 0,063, ! = 0,05), terdapat hubungan signifikan antara obesitas dengan kejadian inkontinensia urin (p-value 0,020, ! = 0,05), terdapat hubungan signifikan anatara jenis operasi dengan kejadian inkontinensia urin (p-value 0,038, ! = 0,05), terdapat hubungan signifikan antara volume prostat dengan kejadian inkontinensia urin (p-value 0,038, ! = 0,05), terdapat hubungan signifikan antara lama operasi dengan kejadian inkontinensia urin (p-value 0,036, ! = 0,05) dan tidak terdapat hubungan signifikan antara waktu operasi dengan kejadian inkontinensia urin (p-value 0,925, ! = 0,05). Pada hasil analisis multivariat menunjukkan bahwa jenis operasi berhubungan paling dominan dengan kejadian inkontinensia urin nilai OR yang terbesar yaitu (2,39) (95% CI: 0,955-5,988). Diharapkan tenaga keperawatan dapat meningkatkan pemahaman melalui pemberian informasi atau pendidikan kesehatan terkait dengan pencegahan inkontinensia urin umumnya generasi muda khususnya pada generasi tua di Kota Jayapura. ......The increase in the life expectancy of the Indonesian population reaching the age of 66.2 years has contributed to an increase in the number of elderly people ( Aging Structured Population ). The aging process causes health problems in the elderly, one of which is urinary incontinence. Urinary incontinence is a bladder sphincter defect or neurological dysfunction that causes loss of control over urination. Urinary incontinence can cause physical, psychological, social and economic problems that affect the quality of life of the elderly. This study aims to identify factors associated with urinary incontinence in patients after prostate surgery at the Urology Polyclinic, Jayapura Hospital in 2023. This study used a cross-sectional design, correlative descriptive approach, and consecutive sampling technique in 90 post-prostate post-operative patients at the polyclinic. Jayapura Hospital Urology. The results showed that there was no significant relationship between age and the incidence of urinary incontinence ( p-value 0.063,! = 0,05) , there is a significant relationship between obesity and urinary incontinence ( p-value 0.020,! = 0,05) , there is a significant relationship between the type of operation and the incidence of urinary incontinence ( p-value 0.038,! = 0,05), there is a significant relationship between Prostate Volume and the incidence of Urinary Incontinence ( p-value 0.038,! = 0,05) , there is a significant relationship between the length of operation and the incidence of urinary incontinence ( p-value 0.036,! =0,05) and there was no significant relationship between operating time and urinary incontinence ( p-value 0.925,! = 0,05). The results of the multivariate analysis showed that the type of surgery was most dominantly related to the incidence of Urinary Incontinence with the largest OR value (2.39) (95% CI: 0.955-5.988). It is hoped that nursing staff can improve understanding through providing information or health education related to the prevention of Urinary Incontinence in general for the younger generation, especially the older generation in Jayapura City.
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2023
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UI - Tesis Membership  Universitas Indonesia Library
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Ihya Ridlo Nizomy
Abstrak :
Latar Belakang: Inkontinensia urin (IU) menurut ICS didefinisikan sebagai keluarnya urin yang tidak dapat dikendalikan atau dikontrol, yang secara obyektif dapat diperlihatkan dan merupakan suatu masalah sosial dan higienis. Pada perempuan, gangguan fungsi berkemih ini sering kali didapatkan pasca-operasi koreksi kelainan Prolaps Organ Panggul (POP). Inkontinensia Urin Tekanan de novo (IUT de novo) adalah IU yang terjadi pada pasien POP pasca-operasi pervaginam yang tidak didapatkan sebelum operasi. Tujuan: Untuk mengetahui kejadian IUT de novo dan faktor risiko yang berhubungan pada pasien POP pasca-operasi pervaginam di Divisi Uroginekologi dan Rekonstruksi Departemen Obstetri dan Ginekologi RSCM Jakarta. Metode: Studi klinis potong lintang yang dilakukan pada 75 orang pasien POP pasca-operasi pervaginam di Divisi Uroginekologi dan Rekonstruksi Departemen Obstetri dan Ginekologi RSCM Jakarta pada bulan Januari 2016 sampai Juli 2017. Penilaian kejadian IUT de novo dan faktor risiko yang berperan dilakukan berdasarkan data Rekam Medik, lembar penilaian Kuesioner QUID (Questionnaire for Urinary Incontinence Diagnosis) versi Indonesia dan dikonfirmasi dengan pemeriksaan Cough Stress Test secara kualitatif dan tes pembalut pad test secara kuantitatif. Hasil: Dari 75 subyek penelitian didapatkan angka kejadian IUT de novo sebesar 8% (6/75). Uji analisis statistik menunjukkan hanya 2 faktor risiko yang berperan secara bermakna (p < 0,05) terhadap kejadian IUT de novo pada pasien POP pasca-operasi pervaginam di RSCM Jakarta, yaitu derajat POP yang berat dan penyakit Diabetes Mellitus dengan nilai OR 0,13 (95% CI 0,02-1,63) dan 23,75 (95%CI 2,29-590,2). Kesimpulan: Pada penelitian ini, angka kejadian IUT de novo pada pasien POP pasca-operasi pervagnam adalah 8% dengan faktor risiko yang berperan adalah derajat POP preoperatif yang berat dan penyakit Diabetes Mellitus.
Background: Stress Urinary Incontinence remains a main women's health problem due to its devastating impacts to the quality of life. Some patients with pelvic organ prolapse (POP) may suffer from stress urinary incontinence (SUI) named de novo SUI after pelvic floor reconstruction2. The epidemiology study of de novo SUI in Indonesia is not known yet. In the world, a few studies have reported a wide range (2-43%) in incidence of de novo SUI following surgical repair of POP in previously continent patients. This study aimed to investigate the occurrence of de novo SUI and determined related risk factors after vaginal surgery on POP patients in Ciptomangunkusumo Hospital Jakarta. Methods: This is a cross-sectional study of 108 patients who underwent pelvic floor vaginal surgery due to pelvic organ prolapse (POP) at the Department of Obstetry and Gynecology, Urogynecology and Recontruction Division in Indonesian University-Ciptomangunkusumo Hospital from January 2016 to December 2017. According to the inclusion and exclusion criteria, 75 patients were enrolled in the study with consecutive sampling technique. The occurrence of de novo SUI was determined 6-12 months postoperatively by using Indonesian version of Questionnaire for Urinary Incontinence Diagnosis (QUID), and objectively by positive Cough Stress Test (CST) during gynecological examination after negative Preoperative Prolapse Reduction Stress Test (PPRST). The clinical characteristic of positively de novo SUI patients identified were age, parity, Body Mass Index, menopause periode before surgery, degree of Pelvic Organ Prolapse based on POP-Q system, type of vaginal surgery and clinical result of Diabetes Mellitus. Thes significant risk factors that contribute for the occurrence of de novo SUI determined by multivariate statistical analysis (95% CI and 𝛼 0.05). Results: The occurrence of de novo SUI was 8% or 6 from 75 patiens 6-7 month postoperative for pelvic floor reconstruction due to POP. Average of age, parity, BMI, menopause periode before surgery, respectively were 56.17 ± 4.67, 3.17 ± 1.07, 28.58 ± 5.18, and 12,8 ± 7,0. There were 50,0% (3/6) patients with severe degree of POP and 50% (3/6) with mild degree of POP with most of them 66,7% (4/6) had underwent non colpocleisis procedure for POP reconstruction. All of the patient but one were positively Diabetes Mellitus according to clinical hystory and laboratory finding, and most of them about 83,3% (5/6) were in menopause state. There were two significant risk facors that contribute to the occurrence of de novo SUI which are severe degree of preoperative POP (p 0.038; OR 0.13 95% CI 0,02-0,63) and Diabetes Mellitus (p 0.02; OR 23.75 95% CI 2.29-590.2). Conclusion: The occurrence of de novo SUI after vaginal surgery of Pelvic Organ Prolapse patients in Ciptomangunkusumo Hospital Jakarta was 8%. Most of them were average of age < 60 years old, parity < 4, non- obese women, in menopausal periode, and diabetic patient. The determinant significant risk factors contribute to the occurrenceof de novo SUI were evere degree of preoperative POP and Diabetes Mellitus.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2018
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UI - Tugas Akhir  Universitas Indonesia Library
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Imam Ahmadi Farid
Abstrak :
ABSTRAK
Nama : Imam Ahmadi FaridNPM : 1406667463Program Studi/Divisi : Obstetri ndash; Ginekologi / Uroginekologi Rekonstruksi Judul: Prevalensi, karakteristik dan Faktor Risiko Terkait Pada Pasien Inkontinensia Urin Dalam Poliklinik Ginekologi Menggunakan Kuesioner Untuk Diagnosis Inkontinensia Urin QUID Versi Bahasa Indonesia Latar belakang: Inkontinensia urin tetap menjadi masalah kesehatan utama wanita karena dampaknya yang menghancurkan terhadap kualitas hidup. Namun, studi epidemiologi tentang inkontinensia urin UI di Indonesia sangat terbatas. Bisa jadi karena keluhan pasien yang kurang dilaporkan. Kami bertujuan untuk menentukan prevalensi, karakteristik dan faktor risiko UI di antara pasien ginekologi. Metode: Pasien mengunjungi klinik rawat jalan ginekologi di Cipto Mangunkusumo, Rumah Sakit Umum, Jakarta, Indonesia yang ditawarkan untuk berpartisipasi dalam penelitian ini. Subyek yang memenuhi syarat melakukan wawancara untuk mengisi kuesioner QUID versi Bahasa Indonesia. Faktor terkait untuk stres inkontinensia urin SUI , mendesak inkontinensia urin UUI , dan kontinum urin campuran MUI diidentifikasi setelah analisis bivariat dan multivariat. Hasil: Prevalensi SUI, UUI, dan MUI masing-masing 4,3 , 3,0 , dan 2,7 di antara 400 subjek yang memenuhi syarat. Usia di atas 61 tahun, usia antara 51 hingga 60 tahun, tingkat pendidikan rendah, kelebihan berat badan, multiparitas, persalinan pervaginam dan keadaan menopause meningkatkan risiko untuk semua jenis UI. Pada analisis multivariat, usia yang lebih tua adalah faktor risiko paling signifikan untuk memiliki UI p = 0,000, OR 5,4 95 CI: 2,13-13,87 . Kesimpulan: Usia di atas 61 tahun, usia antara 51 hingga 60 tahun, tingkat pendidikan rendah, kelebihan berat badan, multiparitas, persalinan pervaginam dan menopause adalah faktor risiko untuk SUI, UUI, dan MUI. Umur adalah faktor terkait yang paling signifikan. Kata kunci: QUID Questionnaire, faktor risiko, inkontinensia urin.
ABSTRACT

Abstract Nama Imam Ahmadi FaridNPM 1406667463Program Studi Divisi Obstetri ndash Ginekologi Uroginekologi Rekonstruksi Title Prevalence, characteristics and Related Risk Factors In Urinary Incontinence Patients In Gynecology Polyclinics Using Questionnaire For Urinary Incontinence Diagnosis QUID Indonesian Version Background Urinary Incontinence remains a main women rsquo s health problem due to its devastating impacts to the quality of life. However, the epidemiology study of urinary incontinence UI in Indonesia is very limited. It could be due to the under reported complaints of the patients. We aim to determine the prevalence, characteristics and risk factors of UI among gynecological patients. Methods Patients visited gynecological outpatient clinic at Cipto Mangunkusumo, General Hospital, Jakarta, Indonesia were offered to be participated in this study. Eligible subjects underwent interview to fulfill Indonesian version of QUID questionnaires. The associated factors for stress urinary incontinence SUI , urge urinary incontinence UUI , and mixed urinary continence MUI were identified after bivariate and multivariate analysis. Results The prevalence of SUI, UUI, and MUI were respectively 4.3 , 3.0 , and 2.7 among 400 eligible subjects. Age over 61 years old, age between 51 to 60 years old, low education level, overweight, multiparity, vaginal delivery and menopausal state were increased the risk for any types of UI. On multivariate analysis, older age was the most significant risk factor for having UI p 0.000, OR 5.4 95 CI 2,13 13,87 . Conclusion Age over 61 years old, age between 51 to 60 years old, low education level, overweight, multiparity, vaginal delivery and menopausal state were the risk factor for SUI, UUI, and MUI. Age was the most significant associated factor. Keywords QUID Questionnaire, risk factors, urinary incontinence
2017
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UI - Tesis Membership  Universitas Indonesia Library
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Astrid Yunita
Abstrak :
Inkontinensia urin tekanan sering ditemukan padakehamilan dengan prevalensi tertinggi pada empat minggu terakhir kehamilan. Diketahui bahwa kelemahan otot dasar panggul merupakan salah satu penyebab inkontinensia urin tekanan. Penelitian ini bertujuan untuk mengetahui hubungan kekuatan otot dasar panggul dengan inkontinensia urin tekanan pada perempuan hamil trimester ketiga akhir, dan faktor-faktor yang mempengaruhinya. Penelitian ini menggunakan desain potong lintang dengan melibatkan perempuan hamil 36-40 minggu di poli Obstetri dan Ginekologi RSUK TebetJakarta. Data yang diperoleh berupa hasil anamnesis, Questionnaire for Urinary Incontinence Diagnosis QUID , pemeriksaan fisik, perineometer, dan tes batuk. Sampel berjumlah 142 orang dengan 54,2 diantaranya mengalami inkontinensia urin tekanan. Diketahui bahwa kekuatan otot dasar panggul dan taksiran berat janin memiliki perbedaan bermakna dengan inkontinensia urin tekanan p = 0,002, < 0,001, secara berurutan . Uji multivariat menunjukkan bahwa kekuatan otot dasar le; 25,5 cmH2O panggul dan TBJ ge; 3.100 gram paling mempengaruhi kejadian inkontinensia urin tekanan OR = 2,52, p= 0,021 dan OR = 3,34, p= 0,001, secara berurutan . Uji probabilitas menunjukkan bahwa apabila TBJ >3.100 gram dan kekuatan otot dasar panggul
Stess urinary incontinence is the most frequent found during pregnancy with the highest prevalence in the last four weeks of pregnancy. It is known that weaken pelvic floor muscle is one of the causes of stress urinary incontinence. This study aims to know the relationship between the strength of pelvic floor muscle and stress urinary incontinence in late third trimester of pregnancy and its associated factors.A cross sectional study was conducted involving women with 36 until 40 weeks of pregnancy at Obstetric and Gynecology clinic of Tebet Subdistrict Hospital, Jakarta. Collected data included medical interview, Questionnaire for Urinary Incontinence Diagnosis QUID , physical examination, perineometer, and cough test. Among 142 samples, 54.2 had stress urinary incontinence. Discovered that pelvic floor muscle, and estimated fetal weight had significant differences with SUI p 0.002, 0.001, respectively . Multivariate analysis showed the strength of pelvic floor muscle le 25.5 cmH2O , and EFW ge 3,100 gram were the most influenced factors for SUI OR 2.52, p 0.021 dan OR 3.34, p 0.001, respectively . The likelihood of SUI was 75.39 if the strength of PFM was le 25.5 cmH2O,and EFW ge 3,100 gram. Weaken pelvic floor muscle, and EFW were the factors influencing SUI.
2018
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UI - Tesis Membership  Universitas Indonesia Library
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Abstrak :
Overactive bladder (OAB) is a clinical syndrome consisting of symptom complex of urgency, with or without incontinence which has significant effects on quality of life and has to be managed properly. The aim of this study was to review the management of OAB by Indonesian urologists. A self-constructed questionnaires containing diagnostic and treatment options of OAB patients were distributed to indonesian urologists. This was a cross-sectional study and descriptive analyze the data. 129 Indonesian urologists participated in this study. Most of them faced more than 20 OAB cases per year with the most common type was OAB without incontinence or dry OAB (57,4%). Most urologists (34.1%) ordered at least three diagnostic tools to determine OAB. They were bladder diary, urinalysis and scoring system. The most used scoring system (48.9%) was the overactive bladder symptoms score (OABSS). Thirty-five point seven percent (35.7%) of urologist used antimuscarinic and behavioral therapy as initial therapy. Solifenacin 5 mg/day was the most common antimuscarinic prescribed as the first line therapy (48%). Most common items commonly evaluated for follow-up: symptoms (96.9%), bladder diary (72.9%); and drug's side effect (58.1%). When initial therapy had failed, most of the urologists (54.3%) chose to increase the dose of antimuscarinic. None of them chose bladder botulinum toxin injection as their additional therapy. OAB is a frequent disorder which remains a challenge for urologists. The management of patients with OAB by Indonesian urologists has been suitable with the previous studies and guidelines.
UI-MJI 24:2 (2015)
Artikel Jurnal  Universitas Indonesia Library
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Kurniawan Suriya
Abstrak :
Ruang lingkup: Benzena, bahan kimia yang berdampak negatif terhadap kesehatan dalam jangka panjang, pada saat ini masih banyak digunakan di industri percetakan. Penelitian ini bertujuan untuk mengetahui hubungan antara umur, pendidikan, status kawin, masa kerja, kebiasaan merokok dan lokasi kerja di lingkungan terpajan benzena dengan tingginya fenol urin. Metodologi: Penelitian ini menggunakan disain krosseksional dan melakukan perhitungan Odd Ratio ( OR ), untuk itu digunakan metode kasus-kontrol. Sebanyak 65 subjek penelitian didapat yang terdiri atas 32 dari lingkungan kerja terpajan tinggi dan 33 dari lingkungan kerja terpajan rendah. Data diperoleh dengan Cara wawancara terstruktur, pemeriksaan fisik dan pemeriksaan sampel urin yang dikumpulkan setelah 8 jam kerja. Hasil penelitian: Kadar uap benzena di lingkungan kerja terpajan tinggi lima kali lebih tinggi dari NAB yang ditetapkan, sedangkan di lingkungan kerja terpajan rendah < 1/10 NAB. Penelitian ini tidak menemukan adanya hubungan bermakna ( p = 0,485 ) antara pajanan uap benzena dengan peningkatan kadar fenol urin. Hanya dua responden dari kelompok terpajan rendah mempunyai kadar normal fenol urin. Kesimpulan: Tidak terbukti adanya hubungan yang bermakna antara peningkatan kadar fenol urin pekerja di lokasi kerja dengan faktor-faktor umur, pendidikan, status kawin, masa kerja, dan kebiasaan merokok. Pajanan terjadi tidak hanya di lokasi kerja terpajan tinggi tapi juga di lokasi kerja terpajan rendah, Walaupun kadar uap benzena di lingkungan kerja terpajan rendah < 1 ppm , kadar fenol urin pekerja di lokasi tersebut rata-rata di atas normal. Karena tingginya kadar uap benzena di lingkungan kerja, manajemen perusahaan perlu menerapkan Kesehatan dan Keselamatan Kerja (K3). Hal ini perlu diperhatikan oleh Hiperkes, Dinas Kesehatan, Departemen Tenaga Kerja, Departemen Kesehatan, Departemen Perindustrian dan Perdagangan dan K3 untuk mencegah dan mengurangi dampak negatif jangka panjang pada pekerja di percetakan tersebut.
Analysis of The Relationship of Urinary Phenol With The Exposure of Benzene Volatile on The Workers at a Printing Company in JakartaScope: Benzene, a chemical substance which has long-term negative impacts on health is still widely used in printing industry. The goal of this study is to find the relationship between age, education, marital status, working period, smoking habit and workplace at the environment exposed to benzene with the increase of urinary phenol. Methodology: This study used cross sectional design. Since Odd Ratio (OR) was also calculated, case-control method had been used. A total number of 65 respondents consisting of 32 workers worked at high-exposed workplace and of 33 workers worked at low-exposed workplace. The data were obtained from structured interview, physical examination and test of urine collected after 8 working-hours. Results: Benzene volatile at the high-exposed workplace is fivefold higher than TLV (threshold limit value), meanwhile at the low-exposed one is less than 1110 of TLV. This study did not find a significant relationship ( p = 0,485 ) between exposure of benzene volatile with the increase of urinary phenol. Only two respondens of low-exposed workplace have normal urinary phenol Conclusion: No relationship was found between the increase of urinary phenol with workplace and all those factors mentioned above. The exposure happened not only at high-exposed but also low-exposed workplace. Although the benzene-volatile at low-exposed workplace is less than 1 ppm, the average of workers' urinary phenol is above normal ( 28,39 mg/1) Due to high exposure of benzene volatile at workplace, the management of this printing industry should apply the Occupational Health and Safety. This should also be noticed by the Industry Hygiene and Occupational Health, Health Service, Departement of Workers, Departement of Health, Departement of Industry and Trade and Occupational Health and Safety to prevent and decrease long-term negative impacts on workers at this company.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2003
T12384
UI - Tesis Membership  Universitas Indonesia Library
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Siti Rafika
Abstrak :
Latar Belakang: Inkontinensia urin (IU) merupakan salah satu masalah kesehatan dengan prevalensi dan beban yang cukup tinggi di dunia. Inkotinensia urin tekanan (SIU) merupakan salah satu bentuk inkontinensia urin dengan prevalensi di Indonesia berkisar antara 14,57-52%. Latihan otot dasar panggul merupakan salah satu pencegahan dan tatalaksana yang direkomendasikan untuk inkontinensia urin. Namun, perbandingan antara efektivitas latihan yang dilakukan selama masa kehamilan dan pasca persalinan belum pernah dilakukan sebelumnya. Tujuan: Penelitian ini bertujuan untuk mengetahui efektivitas latihan otot dasar panggul pada masa kehamilan dan setelah persalinan sebagai pencegahan dan pengobatan terhadap terjadinya inkontinensia urin tekanan yang menetap pasca persalinan. Metode: Dilakukan penelitian dengan desain uji klinis acak terkontrol dan kerangka konsep etiologik. Populasi penelitian yaitu semua ibu hamil dengan gejala inkontinensia urin tekanan. Dalam kurun waktu penelitian didapatkan sampel sebanyak 70 ibu hamil dengan gejala inkontinensia urin tekanan pasca persalinan yang dibagi dalam kelompok tanpa intervensi, kelompok latihan otot dasar panggul sejak masa kehamilan, dan kelompok latihan otot dasar panggul pasca persalinan. Data dianalisis dengan metode analisis bivariat kategorik tidak berpasangan dua kelompok. Hasil: Dari hasil penelitian ini, didapatkan adanya hubungan yang bermakna pada ibu hamil yang diberikan latihan otot dasar panggul baik sejak masa kehamilan (p-value = 0.002) maupun pasca persalinan (p-value = 0.006) dengan penurunan proporsi kejadian inkontinensia urin tekanan menetap pasca persalinan. Namun, tidak didapatkan adanya perbedaan hasil yang bermakna secara statistik antara kelompok ibu hamil yang diberikan latihan otot dasar panggul sejak masa kehamilan dengan yang diberikan latihan pasca persalinan (p-value = 1.000). Kesimpulan: Pada penelitian ini tidak didapatkan adanya perbedaan yang bermakna antara latihan otot dasar panggul pada masa kehamilan dan setelah persalinan. Namun, latihan otot dasar panggul pada masa kehamilan dan setelah persalinan terbukti efektif dalam pencegahan dan pengobatan terhadap terjadinya inkontinensia urin tekanan yang menetap pasca persalinan dibandingkan dengan yang tidak melakukan. ...... Background: Urinary incontinence (UI) is one of the problematic health problems with high prevalence and monetary burden in the world. Stress urinary incontinence is one form of UI with a prevalence of 14.57 -52% in Indonesia. Pelvic floor muscle training (PFMT) is one of its recommended preventive and curative measures. Nevertheless, comparison between PFMT initiated during pregnancy period and postpartum period has never been studied before. Objective: This study aims to determine the effectiveness of pelvic floor muscle exercises during pregnancy and after childbirth as prevention and treatment of the occurrence of persistent postpartum urinary incontinence. Method: A randomized controlled trials with an etiological conceptual framework was done in this study. The study population were all pregnant women with symptoms of urinary incontinence. In the study period, a sample of 70 pregnant women with symptoms of postpartum urinary incontinence consisting of no-intervention group, pregnancy PFMT group, and postpartum PFMT group. The data were analyzed by two groups of unpaired categorical bivariate analysis methods. Results: It was found that there was a significant association between pregnant women given pelvic floor muscle training (PFMT) both during pregnancy (p-value = 0.002) and postpartum (p-value = 0.006) with decline of persistent postpartum urinary incontinence proportion. However, there was no statistically significant difference of outcome found in the group of pregnant women given PFMT since pregnancy with those who were given after childbirth, p-value = 1,000. Conclusion: In this study there was no significant difference of outcome between PFMT during pregnancy and after delivery. However, PFMT during pregnancy and after childbirth have been proven effective in the prevention and treatment of the occurrence of postpartum urinary incontinence compared with those who did not.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2019
T58707
UI - Tesis Membership  Universitas Indonesia Library
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Maisa Weli
Abstrak :
Pendahuluan: Benzo(a)pyrene merupakan salah satu golongan PAH yangdiklasifikasikan sebagai senyawa yang bersifat karsinogen (probably carcinogenic)pada manusia dan hewan. Setelah terpajanan, benzo(a)pyrene yang masuk kedalamtubuh manusia melalui jalur inhalasi, langsung terabsorpsi didalam tubuh danterdistribusi dalam paru, kulit dan hati, lalu berikatan dengan DNA, RNA dan protein. Setelah memasuki tubuh manusia dan biotransformasi, Benzo(a)pyrene diekskresikan dalam bentuk metabolit terhidroksilasi dalam urin atau feses. 1-hydroxypyrene (1-OHP) dalam urin merupakan metabolit yang paling umum digunakan sebagai biomarker pajanan dari senyawa benzo(a)pyrene. Pengukuran konsentrasi benzo(a)pyrene dilakukan pada tiga titik di setiap sekolah menggunakan sorben tube dengan filter charcoal, dan dianalisis menggunakan metode fluoresensi. Analisis 1-hydroxypyrene dalam urin dilakukan menggunakan HPLC dengan detektor fluoresensi. Tujuan: untuk melihat hubungan paparan benzo(a)pyrene terhadap konsentrasi 1-hydroxypyrene pada urin. Metode: Penelitian ini merupakan penelitian kuantitatif dengan desain cross sectional, sampel dalam penelitian ini berjumlah 76 orang, pembagian sampel di buat secara probability proportional to size (PPS), pengambilan sampel menggunakan purposive sampling. Hasil: Rata-rata konsentrasi BaP di udara indoor sekolah dasar negeri di sekitar ruas jalan utama Jakarta Barat sebesar 0,0059 mg/m3, dan rata-rata konsentrasi BaP di udara outdoor yaitu 0,0031 mg/m3. Rata-rata konsentrasi BaP di udara indoor pada sekolah terpajan tinggi yaitu 5,6 kali lebih tinggi (0,0102 mg/m3) di bandingkan sekolah yang terpajan terpajan rendah (0,0018 mg/m3). Rata-rata konsentrasi 1-OHP pada urin siswa sekolah dasar negeri di sekitar ruas jalan utama Jakarta Barat adalah 12,146 μmol/mol kreatinin. Rata-rata konsentrasi 1-OHP pada urin siswa sekolah terpajan tinggi 1,2 kali lebih besar (13,363 μmol/mol kreatinin) di bandingkan sekolah terpajan rendah (10,929 μmol/mol kreatinin). Kesimpulan: Hubungan pajanan BaP di udara indooor terhadap konsentrasi 1-OHP pada urin siswa berpola positif dimana terdapat korelasi positif antara pajanan BaP di udara indoor terhadap peningkatan konsentrasi 1-OHP pada urin siswa (r=0,229) artinya semakin tinggi pajanan BaP di udara indoor maka semakin tinggi konsentrasi 1-OHP pada urin siswa. Hasil uji statistik menjelaskan ada hubungan yang signifikan antara pajanan BaP di udara indoor dengan konsentrasi 1-OHP pada urin siswa (p=0,046). ...... Introduction: Benzo(a)pyrene is a class of PAH which is classified as a carcinogenic compound (probably carcinogenic) in humans and animals. After exposure, benzo(a)pyrene which enters the human body through inhalation pathways, is directly absorbed in the body and distributed in the lungs, skin, and liver, then binds to DNA, RNA, and protein. After entering the human body and biotransformation, benzo(a)pyrene is excreted in the form of hydroxylated metabolites in urine or feces. 1-hydroxypyrene (1-OHP) in urine is the most common metabolite used as exposure biomarkers of benzo(a)pyrene compounds. Benzo(a)pyrene concentration measurements were carried out at three points in each school using tube sorbents with charcoal filters and analyzed using the fluorescence method. Analysis of 1-hydroxypyrene in urine is carried out using HPLC with a fluorescence detector. Objective: To see the relationship of exposure to benzo(a)pyrene to urine 1-hydroxypyrene concentration. Method: This study is a quantitative study with a crosssectional design, the sample in this study amounted to 76 people, the sample distribution was made by probability proportional to size (PPS), the sampling used purposive sampling. Results: The average BaP concentration in the indoor air of public elementary schools around the West Jakarta's main road segment is 0.0059 mg/m3, and the average BaP concentration in outdoor air is 0.0031 mg/m3. The average BaP concentration in indoor air in high exposed schools is 5.6 times higher (0.0102 mg/m3) compared to schools exposed to a low exposure (0.0018 mg/m3). The average 1-OHP concentration in the urine of public elementary school students around the West Jakarta main road segment is 12.146 μmol/mol creatinine. The average concentration of 1-OHP in the urine of high-exposed school students was 1.2 times greater (13,363 μmol/mol creatinine) compared to low-exposed schools (10,929 μmol/mol creatinine). Conclusion: The relationship of BaP exposure in indoor air to the concentration of 1-OHP in the urine of students was positively patterned where there was a positive correlation between BaP exposure in indoor air to an increase in 1-OHP concentration in the urine of students (r = 0.229) meaning higher exposure to indoor air the higher the concentration of 1-OHP in the urine of students. The results of the statistical test explained that there was a significant relationship between exposure to BaP in indoor air and the concentration of 1-OHP in the urine of students (p = 0.046).
Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2019
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Asih Anggraeni
Abstrak :
ABSTRAK
Inkontinensia urin sering ditemukan pada 50% wanita yang berusia dibawah 60. Yang terbanyak adalah inkontinensia urin jenis tekanan (IUT) sebesar 49%. Diketahui bahwa kelemahan otot dasar panggul merupakan salah satu penyebab inkontinensia urin jenis tekanan. Penelitian ini bertujuan untuk mengkaji hubungan antara kekuatan otot dan ketebalan otot levator ani dengan keluhan IU-T pada perempuan. Penelitian ini menggunakan desain Comparative Cross Sectional dengan melibatkan wanita yang berkunjung di poliklinik Obstetri dan Ginekologi RSUPN Dr. Cipto Mangunkusumo dengan kelompok studi adalah subyek dengan tes batuk positif sedangkan kelompok kontrol adalah subyek dengan tes batuk negative. Data yang diperoleh berupa hasil anamnesis, Questionnaire for Urinary Incontinence Diagnosis (QUID), pemeriksaan fisik (POPQ), tes batuk. perineometer, dan USG. Sampel berjumlah 82 orang. Hasil penelitian ini didapatkan tidak ada perbedaan bermakna antara ketebalan otot levator ani terhadap kejadian IUT dengan median ketebalan otot levator ani 0,63 cm (range 0,31-1,02 dan p=0,897). Sedangkan kekuatan otot levator ani terhadap IUT memiliki median 19,5 (range 4,6-88,6 dan p=0,001). Pada analisis multivariat didapatkan bukti bahwa secara murni IUT, prolap dan usia tidak mempunyai pengaruh bermakna terhadap kekuatan otot levator ani dengan nilai p masing-masing 0,243; 0,844; 0,903.
ABSTRACT
Urinary incontinence is often found in 50% of women under the age of 60. The most common is pressure type urinary incontinence (IUT) of 49%. It is known that pelvic floor muscle weakness is one of the causes of pressure type urinary incontinence. This study aims to examine the relationship between muscle strength and levator ani muscle thickness with IU-T complaints in women. This study uses a Comparative Cross Sectional design by involving women visiting the Obstetrics and Gynecology clinic of RSUPN Dr. Cipto Mangunkusumo with the study group were subjects with positive cough tests while the control group were subjects with negative cough tests. The data obtained in the form of history taking, Questionnaire for Urinary Incontinence Diagnosis (QUID), physical examination (POPQ), cough test. perineometer, and ultrasound. A sample of 82 people. The results of this study found no significant difference between the levator ani muscle thickness to the incidence of IUT with the median levator ani muscle thickness 0.63 cm (range 0.31-1.02 and p = 0.897). While levator ani muscle strength against IUT has a median of 19.5 (range 4.6-88.6 and p = 0.001). In multivariate analysis it was found that purely IUT, prolapse and age had no significant effect on the strength of levator ani muscles with a p value of 0.243 each; 0.844; .903.
Depok: Fakultas Kedokteran Universitas Indonesia, 2020
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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