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Abstrak :
ABSTRAK
Pertumbuhan penduduk meningkatkan kebutuhan suplai air bersih. Masalah kondisi kualitas, kuantitas, dan kontinuitas air baku di DKI Jakarta membuat pasokan air menjadi langka. Masalah tersebut dapat diatasi dengan intervensi teknologi pengolahan sumber air sehingga pelayanan pasokan air bersih di provinsi DKI Jakarta meningkat. Banjir Kanal Timur BKT adalah salah satu fasilitas infrastruktur di Provinsi DKI Jakarta yang berpotensi menjadi sumber air baku. Penelitian ini bertujuan menganalisis pemilihan teknologi pra pengolahan yang tepat untuk memperbaiki kualitas air BKT. Metode Analytical Hierarchy Process digunakan untuk menentukan teknologi pra pengolahan yang tepat untuk memperbaiki kualitas air BKT berdasarkan persepsi 5 orang ahli dari instansi berbeda dengan 3 pilihan alternatif teknologi, yaitu MBBR Moving Bed Biofilm Reactor , MBR Membrane Bioreactor , dan Bank Filtration. Hasil penelitian ini menunjukkan bahwa teknologi MBBR memperoleh bobot tertinggi sebesar 0,51, sedangkan MBR sebesar 0,38, dan BF sebesar 0,12. Kesimpulannya adalah air BKT berpotensi menjadi air baku dengan teknologi MBBR sebagai teknologi yang paling tepat untuk pengolahan air Banjir Kanal Timur.

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ABSTRACT
Population growth increases the need for clean water supplies. The problem of quality, quantity, and continuity of raw water in DKI Jakarta make water supply become scarce. This condition can be solved by the intervention of water source processing technology so that raw water supply service in DKI Jakarta province increases. East Flood Canal BKT is one of the infrastructure facilities in DKI Jakarta that has the potential to become a source of raw water. This study aims to analyze the selection of appropriate pre processing technology to improve the water quality of BKT. The Analytical Hierarchy Process method is used to determine the appropriate pre processing technology to improve the water quality of BKT based on perceptions of 5 experts from different agencies with 3 alternative technology options, namely MBBR Moving Bed Biofilm Reactor , MBR Membrane Bioreactor , and Bank Filtration. The results of this study indicate that MBBR technology obtained the highest weight of 0.51, while the MBR of 0.38, and BF of 0.12. The conclusion is that BKT water has the potential to become raw water with MBBR technology as the most appropriate technology for water treatment of East Flood Canal.

Abstrak :
[Aspergillus flavus UICC 360 merupakan fungi yang mampu menghasilkan senyawa metabolit sekunder berupa lovastatin. Penelitian bertujuan untuk mengetahui pengaruh variasi konsentrasi urea terhadap kemampuan Aspergillus flavus UICC 360 dalam menghasilkan lovastatin. Proses fermentasi menggunakan konsentrasi inokulum Aspergillus flavus UICC 360 sebesar 1,96% (v/v) dalam medium Czapek?s Dox Broth (CDB) modifikasi dengan variasi konsentrasi urea (0 mM, 33 mM, 42 mM, 50 mM, 58 mM, dan 67 mM) dan inkubasi selama 7 hari pada suhu ruang (27--300C) dengan kecepatan agitasi 90 rpm. Ekstrak hasil fermentasi dalam etil asetat diuji terhadap Candida albicans UICC Y-29 menggunakan metode difusi agar cara cakram. Ekstrak hasil fermentasi dari konsentrasi urea 42 mM mempunyai indeks penghambatan rata-rata tertinggi sebesar 0,54 ± 0,15. Hasil Kromatografi Lapis Tipis (KLT) menunjukkan bahwa nilai Rf ekstrak hasil fermentasi dari konsentrasi urea 42 mM sama dengan lovastatin standar, yaitu 0,42 yang mengindikasikan ekstrak mengandung lovastatin. Uji Least Significant Difference (LSD) (P < 0,05) menunjukkan terdapat perbedaan nyata variasi konsentrasi urea terhadap kemampuan Aspergillus flavus UICC 360 dalam menghasilkan lovastatin. Hal tersebut menunjukkan bahwa pemberian variasi konsentrasi urea berpengaruh terhadap kemampuan Aspergillus flavus UICC 360 dalam menghasilkan lovastatin.;Aspergillus flavus UICC 360 is capable of producing secondary metabolites such as lovastatin. The study aims to determine the effect of variations of urea concentration on the ability of Aspergillus flavus UICC 360 to produce lovastatin. The fermentation process using 1.96% (v/v) inoculum concentration of Aspergillus flavus UICC 360 in the Czapek?s Dox Broth (CDB) medium modified with urea concentration variations (0 mM, 33 mM, 42 mM, 50 mM, 58 mM, and 67 mM) and incubated for 7 days at room temperature (27--30 °C) with agitation speed of 90 rpm. Ethyl acetate extracts were tested against Candida albicans UICC Y-29 using agar disc diffusion method. The extract from fermentation medium of 42 mM urea has the highest average of inhibition index of 0.54 ± 0.15. Results of Thin Layer Chromatography (TLC) showed that the extract from fermentation medium of 42 mM urea has the same Rf value with lovastatin standard Rf 0.42 which indicated that the extract contained lovastatin. Least Significant Difference (LSD) test showed that there were significant difference in the urea concentration variation in the ability of Aspergillus flavus UICC 360 to produce lovastatin. It shows that variation of urea concentrations affect the ability of Aspergillus flavus UICC 360 to produce lovastatin., Aspergillus flavus UICC 360 is capable of producing secondary metabolites such as lovastatin. The study aims to determine the effect of variations of urea concentration on the ability of Aspergillus flavus UICC 360 to produce lovastatin. The fermentation process using 1.96% (v/v) inoculum concentration of Aspergillus flavus UICC 360 in the Czapek’s Dox Broth (CDB) medium modified with urea concentration variations (0 mM, 33 mM, 42 mM, 50 mM, 58 mM, and 67 mM) and incubated for 7 days at room temperature (27--30 °C) with agitation speed of 90 rpm. Ethyl acetate extracts were tested against Candida albicans UICC Y-29 using agar disc diffusion method. The extract from fermentation medium of 42 mM urea has the highest average of inhibition index of 0.54 ± 0.15. Results of Thin Layer Chromatography (TLC) showed that the extract from fermentation medium of 42 mM urea has the same Rf value with lovastatin standard Rf 0.42 which indicated that the extract contained lovastatin. Least Significant Difference (LSD) test showed that there were significant difference in the urea concentration variation in the ability of Aspergillus flavus UICC 360 to produce lovastatin. It shows that variation of urea concentrations affect the ability of Aspergillus flavus UICC 360 to produce lovastatin.]

Abstrak :
[Aspergillus flavus UICC 360 merupakan fungi yang mampu menghasilkan senyawa metabolit sekunder berupa lovastatin. Penelitian bertujuan untuk mengetahui pengaruh variasi konsentrasi urea terhadap kemampuan Aspergillus flavus UICC 360 dalam menghasilkan lovastatin. Proses fermentasi menggunakan konsentrasi inokulum Aspergillus flavus UICC 360 sebesar 1,96% (v/v) dalam medium Czapek’s Dox Broth (CDB) modifikasi dengan variasi konsentrasi urea (0 mM, 33 mM, 42 mM, 50 mM, 58 mM, dan 67 mM) dan inkubasi selama 7 hari pada suhu ruang (27--300C) dengan kecepatan agitasi 90 rpm. Ekstrak hasil fermentasi dalam etil asetat diuji terhadap Candida albicans UICC Y-29 menggunakan metode difusi agar cara cakram. Ekstrak hasil fermentasi dari konsentrasi urea 42 mM mempunyai indeks penghambatan rata-rata tertinggi sebesar 0,54 ± 0,15. Hasil Kromatografi Lapis Tipis (KLT) menunjukkan bahwa nilai Rf ekstrak hasil fermentasi dari konsentrasi urea 42 mM sama dengan lovastatin standar, yaitu 0,42 yang mengindikasikan ekstrak mengandung lovastatin. Uji Least Significant Difference (LSD) (P < 0,05) menunjukkan terdapat perbedaan nyata variasi konsentrasi urea terhadap kemampuan Aspergillus flavus UICC 360 dalam menghasilkan lovastatin. Hal tersebut menunjukkan bahwa pemberian variasi konsentrasi urea berpengaruh terhadap kemampuan Aspergillus flavus UICC 360 dalam menghasilkan lovastatin.;Aspergillus flavus UICC 360 is capable of producing secondary metabolites such as lovastatin. The study aims to determine the effect of variations of urea concentration on the ability of Aspergillus flavus UICC 360 to produce lovastatin. The fermentation process using 1.96% (v/v) inoculum concentration of Aspergillus flavus UICC 360 in the Czapek’s Dox Broth (CDB) medium modified with urea concentration variations (0 mM, 33 mM, 42 mM, 50 mM, 58 mM, and 67 mM) and incubated for 7 days at room temperature (27--30 °C) with agitation speed of 90 rpm. Ethyl acetate extracts were tested against Candida albicans UICC Y-29 using agar disc diffusion method. The extract from fermentation medium of 42 mM urea has the highest average of inhibition index of 0.54 ± 0.15. Results of Thin Layer Chromatography (TLC) showed that the extract from fermentation medium of 42 mM urea has the same Rf value with lovastatin standard Rf 0.42 which indicated that the extract contained lovastatin. Least Significant Difference (LSD) test showed that there were significant differences in the urea concentration variation in the ability of Aspergillus flavus UICC 360 to produce lovastatin. It shows that variation of urea concentrations affect the ability of Aspergillus flavus UICC 360 to produce lovastatin., Aspergillus flavus UICC 360 is capable of producing secondary metabolites such as lovastatin. The study aims to determine the effect of variations of urea concentration on the ability of Aspergillus flavus UICC 360 to produce lovastatin. The fermentation process using 1.96% (v/v) inoculum concentration of Aspergillus flavus UICC 360 in the Czapek’s Dox Broth (CDB) medium modified with urea concentration variations (0 mM, 33 mM, 42 mM, 50 mM, 58 mM, and 67 mM) and incubated for 7 days at room temperature (27--30 °C) with agitation speed of 90 rpm. Ethyl acetate extracts were tested against Candida albicans UICC Y-29 using agar disc diffusion method. The extract from fermentation medium of 42 mM urea has the highest average of inhibition index of 0.54 ± 0.15. Results of Thin Layer Chromatography (TLC) showed that the extract from fermentation medium of 42 mM urea has the same Rf value with lovastatin standard Rf 0.42 which indicated that the extract contained lovastatin. Least Significant Difference (LSD) test showed that there were significant differences in the urea concentration variation in the ability of Aspergillus flavus UICC 360 to produce lovastatin. It shows that variation of urea concentrations affect the ability of Aspergillus flavus UICC 360 to produce lovastatin.]