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"Latar belakang: Keterampilan minum oral merupakan proses yang kompleks dalam perawatan bayi prematur di ruang perawatan intensif neonatus. Peningkatan keterampilan minum oral melibatkan peran serta ibu melalui pembentukan dyadic interaction untuk mengoptimalkan nutrisi bayi prematur Tujuan: Penelitian bertujuan menganalisis pengaruh Model Intervensi Keperawatan Berfokus Nutrisi terhadap keterampilan minum oral, grafik pertumbuhan bayi prematur, dyadic interaction, dan pengetahuan ibu. Metode: Penelitian mixed methods dengan pendekatan sekuensial eksploratori. Tahap I merupakan studi deskriptif kualitatif eksploratif pada 12 perawat neonatus. Tahap II adalah penyusunan model melalui analisis dan sintesis hasil penelitian tahap I dengan melibatkan tiga pakar. Tahap III adalah validasi model melalui penelitian kuasi eksperimen. Hasil: Teridentifikasi tujuh tema pada penelitian tahap I, yang selanjutnya dijadikan dasar menyusun tiga konsep model pada penelitian tahap II. Tiga konsep model tersebut meliputi: (1) Menciptakan lingkungan terapeutik untuk stimulasi keterampilan minum oral; (2) Membentuk interaksi ibu dengan bayi prematur untuk mengoptimalkan pemberian nutrisi; dan (3) Melibatkan peran serta ibu dan keluarga dalam persiapan perawatan bayi prematur dengan ketidakmampuan minum oral di rumah. Perangkat model yang dihasilkan adalah modul, buku kerja, dan selebaran. Analisis GLM Repeated Measure menunjukkan perbedaan keterampilan minum oral (p value < 0,001), berat badan (p value 0,64), panjang badan (p value 0,72), lingkar kepala (p value 0,28), dyadic interaction (p value < 0,001), pengetahuan ibu (p value < 0,001). Simpulan: Model Intervensi Keperawatan Berfokus Nutrisi efektif meningkatkan keterampilan minum oral, dyadic interaction, pengetahuan ibu, namun belum bermakna terhadap grafik pertumbuhan. Saran: Model Intervensi Keperawatan Berfokus Nutrisi dapat diimplementasikan di ruang perawatan intensif neonatus.

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Background: Oral feeding skills are a complex process in the care of premature infants in the neonatal intensive care unit. Improving oral feeding skills involves maternal participation through the formation of dyadic interaction to optimize optimize premature infant nutrition. Objective: The study aimed to analyse the impact of the Nutrition-Focused Nursing Intervention Model on oral feeding skills, growth charts of premature infants, dyadic interaction, and maternal knowledge. Method: This mixed-methods study used a sequential exploratory approach. Stage I was an exploratory descriptive qualitative study involving 12 neonatal nurses. Stage II involved developing a model through analysis and synthesis of the results from Stage I, with input from three experts. Stage III was a model validation through quasi-experimental research. Result: Seven themes were identified in Stage I, which became the basis for developing three model concepts in Stage II. The three model concepts included: (1) Creating a therapeutic environment for stimulating oral feeding skills; (2) Forming interactions between mothers and premature infants to optimize the nutrition; and (3) Involving mothers and families in preparing for the care of premature infants with oral feeding disabilities at home. The resulting model tools included a module, workbook, and leaflet. GLM Repeated Measures analysis showed differences in oral feeding skills (p-value < 0.001), body weight (p-value 0.64), body length (p-value 0.72), head circumference (p-value 0.28), dyadic interaction (p-value < 0.001), and maternal knowledge (p-value < 0.001). Conclusion: The Nutrition-Focused Nursing Intervention Model effectively improved oral feeding skills, dyadic interaction, and maternal knowledge, but did not significantly affect growth charts. Suggestion: The Nutrition-Focused Nursing Intervention Model can be implemented in neonatal intensive care units."

"Latar belakang: Sekitar 10,6% persalinan di seluruh dunia adalah persalinan prematur. Pemantauan pertumbuhan yang adekuat dalam perawatan bayi prematur penting untuk mencegah kelebihan atau kekurangan asupan nutrisi, yang saat ini dapat dilakukan menggunakan kurva Fenton 2013 atau kurva INTERGROWTH-21st. Karena perbedaan metodologi dan populasi yang terlibat pada proses penyusunan kedua kurva, hasil yang didapatkan dapat berbeda. Oleh karena itu, dibutuhkan penelitian untuk membandingkan penggunaan kedua kurva tersebut pada populasi bayi prematur di Indonesia.Metode: Penelitian kohort prospektif ini melibatkan subjek bayi prematur dengan usia gestasi lahir 28–36 minggu di RSUPN Dr. Cipto Mangunkusumo selama Juni–September 2022. Seluruh subjek dipantau dengan kurva Fenton dan kurva INTERGROWTH-21st selama 2 minggu, dan dievaluasi perbedaan persentil berat badan, panjang badan, dan lingkar kepala, proporsi SGA, AGA, dan LGA, dan perbandingan proporsi subjek dengan EUGR pada usia 2 minggu.Hasil: Dari 131 subjek yang memenuhi kriteria inklusi, didapatkan persentil berat badan, panjang badan, dan lingkar kepala lebih tinggi secara bermakna pada kurva INTERGROWTH-21st dibandingkan kurva Fenton. Sebanyak 17 dari 36 (47,2%) subjek yang tergolong SGA berdasarkan kurva Fenton pada saat lahir didapatkan lebih sesuai dengan AGA berdasarkan kurva INTERGROWTH-21st, dan 30 dari 89 (33,7%) subjek yang tergolong AGA berdasarkan kurva Fenton saat lahir didapatkan lebih sesuai dengan LGA berdasarkan kurva INTERGROWTH-21st. Subjek yang lahir sesuai AGA tetapi mengalami EUGR pada usia 2 minggu didapatkan lebih tinggi secara bermakna pada kurva Fenton (14,7%) dibandingkan kurva INTERGROWTH-21st (8,9%, p <0,001).Kesimpulan: Insidens SGA didapatkan lebih tinggi pada kurva Fenton dibandingkan INTERGROWTH-21st, sedangkan LGA lebih tinggi pada kurva INTERGROWTH-21st dibandingkan kurva Fenton. Pada usia kronologis 2 minggu, insidens subjek dengan EUGR lebih tinggi secara bermakna dengan kurva Fenton dibandingkan kurva INTERGROWTH-21st.

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Background: Approximately 10.6% of all deliveries worldwide are premature. Adequate growth monitoring is essential in the care of preterm infants to prevent excessive or undernutrition, which can currently be performed using the Fenton 2013 curve or the INTERGROWTH-21st curve. Due to differences in the methods and study population involved in the development of these two curves, there is a high possibility of obtaining different results. Therefore, a study is warranted to compare the two curves in the Indonesian premature infant population.

Methods: This prospective cohort study involves premature neonates with gestational age of 28–36 weeks born in Cipto Mangunkusumo Hospital during June–September 2022. The growth of all subjects were plotted on the Fenton and INTERGROWTH-21st curves for 2 weeks, and differences in weight, height, and head circumference percentiles, proportion of SGA, AGA, and LGA, and proportion of infants with weight below the 10th percentile between the two curves at 2 weeks were also compared.

Results: Among 131 subjects meeting the inclusion criteria, the weight, height, and head circumference percentiles were significantly higher on the INTERGROWTH-21st curve compared to the Fenton curve. As many as 17 of 36 (47.2%) subjects classified as SGA on the Fenton curve were AGA on the INTERGROWTH-21st curve, and 30 of 89 (33.7%) subjects classified as AGA on the Fenton curve were LGA on the INTERGROWTH-21st curve. The prevalence of infants without SGA at birth but classified as EUGR at 2 weeks was significantly higher on the Fenton curve (14.7%) than the INTERGROWTH-21st curve (8.9%, p <0.001).

Conclusion: The incidence of SGA was significantly higher with the Fenton curve, whereas LGA was significantly higher with the INTERGROWTH-21st curve. At 2 weeks, the proportion of subjects with EUGR was significantly higher with the Fenton curve compared to the INTERGROWTH-21st curve."

"[ABSTRAKKemampuan ibu mengenal isyarat bayi sangat bervariasi dan penting bagi perkembangan bayi prematur. Penelitian ini mengidentifikasi pengaruh pemberian edukasi melalui buku saku pada kelompok kontrol, di sisi lain video berdurasi 10,51 menit dan ?kartu isyarat? sebagai latihan identifikasi isyarat bayi prematur diberikan pada kelompok intervensi. Rancangan menggunakan eksperimen acak terkontrol dengan teknik pretest posttest equivalent group melibatkan 30 ibu dan bayi prematur. Instrumen untuk menilai interaksi ibu-bayi yang digunakan adalah Modified Observation of Communication Interaction. Hasil penelitian menunjukkan adanya pengaruh pemberian edukasi terhadap skor interaksi ibu-bayi yang meningkat bermakna pada kelompok intervensi (p=0,005) dan kelompok kontrol (p=0,011), serta terdapat perbedaan yang bermakna antara kedua kelompok (p=0,015). Peningkatan pemahaman ibu tentang identifikasi isyarat bayi prematur sebaiknya menggunakan video dan latihan.

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ABSTRACTMother?s ability to recognize cues were varies greatly and it is important for infants development. This study was to examine the impact of education method using booklet on controled group, on the other hand 10,51 minutes video and ?cues card? to recognize directly are given on intervention group. This study used a randomized controled trial with pretest posttest equivalent group design. Thirty mothers and premature infants were selected. A Modified Observation of Communication Interaction used to observe mother-infant interaction. The result shown a significant effect of education on mother-infant interaction?s score that increase significantly in the intervension group (p=0,005) and controled group (p=0,011), there were different mean between two group (p=0,015). To improve understanding?s mother of premature infants cue should use video and training, Mother’s ability to recognize cues were varies greatly and it is important for infants development. This study was to examine the impact of education method using booklet on controled group, on the other hand 10,51 minutes video and ‘cues card’ to recognize directly are given on intervention group. This study used a randomized controled trial with pretest posttest equivalent group design. Thirty mothers and premature infants were selected. A Modified Observation of Communication Interaction used to observe mother-infant interaction. The result shown a significant effect of education on mother-infant interaction’s score that increase significantly in the intervension group (p=0,005) and controled group (p=0,011), there were different mean between two group (p=0,015). To improve understanding’s mother of premature infants cue should use video and training]"

"Kesulitan menyusu merupakan masalah yang sering terjadi pada bayi prematur. Tujuan dari studi kasus ini adalah melakukan analisis optimalisasi pemenuhan kebutuhan nutrisi oral pada bayi prematur melalui edukasi perencanaan pulang pada orang tua dengan pendekatan Teori Konservasi Levine. Lima kasus terpilih menunjukkan terjadi masalah keperawatan defisit nutrisi dan menyusui tida efektif. Pendekatan Teori Konservasi Levine dilakukan dengan menggunakan prinsip konservasi energi, konservasi integritas struktural, konservasi integritas personal, dan konservasi integritas sosial. Hasil pemberian asuhan keperawatan menunjukkan bahwa pengetahuan dan keterampilan ibu menyusui bayi meningkat sehingga pemenuhan kebutuhan nutrisi bayi terpenuhi dan meningkatkan berat badan bayi melalui edukasi perencanaan pulang. Perawat dapat menjadikan intervensi tersebut sebagai standar prosedur operasional pada bayi prematur yang mengalami kesulitan menyusu.

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Having difficulty in breastfeeding is a common problem on premature infants. The purpose of this study is to analyze the optimization of the oral fulfillment of nutritional needs in premature infants through discharge planning education for the parents using Levine rsquo s Conservation Theory. Five chosen cases shows the occurrences of nutritional deficit nursing problems. Levine rsquo s Conversation Theory approach is done using energy conservation principle, structural integrity conservation, personal integrity conservation, and social integrity conservation.

The research result from the intervention of discharge planning education with Levine rsquo s Conservation Theory could improve the mothers rsquo knowledge and skills so that the fulfillment of nutritional needs of the infants fulfilled and also increasing the infants rsquo weight. Nurse could make the intervention as a standard procedure for premature infants who experienced breastfeeding difficulty."

"Pengetahuan dan keterampilan perawat dalam melakukan posisi prone pada bayi prematur memiliki peran penting karena apabila tidak dilakukan dengan tepat dapat berpengaruh terhadap pertumbuhan dan perkembangan bayi tersebut. Penelitian ini dilakukan untuk mengetahui efektivitas video posisi prone berbasis telefon pintar terhadap pengetahuan, sikap dan keterampilan perawat dalam melakukan posisi prone dengan tepat. Penelitian ini menggunakan desain randomized control trial dengan melibatkan 58 perawat NICU-Perinatologi pada salah satu Rumah Sakit Rujukan di Jakarta yang diambil menggunakan teknik purposive sampling. Hasil penelitian menunjukkan intervensi video posisi prone berbasis telefon pintar terbukti efektif meningkatkan pengetahuan, sikap dan keterampilan perawat dalam melakukan posisi prone pada bayi prematur (p<0,001, α<0,05). Penelitian memberikan saran supaya hasil penelitian ini dapat menjadi rujukan optimalisasi pengetahuan, sikap, dan keterampilan perawat dengan pemanfaatan teknologi informasi yaitu video tujuh langkah melakukan posisi prone dengan tepat berbasis telefon pintar yang dirancang dengan menarik dan memungkinkan akses secara fleksibel.

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Nurses' knowledge and skills in prone positions on premature babies have an important role because if it is not done properly, it can affect the growth and development of the baby. This study was conducted to determine the effectiveness of smartphone-based prone position videos on nurses' knowledge, attitudes, and skills in performing the prone position correctly. This study used a randomized control trial design involving 58 NICU-Perinatology nurses at a Referral Hospital in Jakarta taken using a purposive sampling technique. The results showed that the smartphone-based prone position video intervention improved nurses' knowledge, attitudes, and skills in performing positions. prone in premature infants (p<0.001, <0.05). The study provides suggestions so that the results of this study can be a reference for optimizing the knowledge, attitudes, and skills of nurses by utilizing information technology, namely a seven-step video of doing the correct prone position based on a designed smartphone attractively and allows flexible access."

"Masalah kesehatan yang paling sering dialami oleh bayi prematur adalah masalah sistem pencernaan sehingga peningkatan berat badan sesuai target tidak dapat tercapai. Tujuan dari studi kasus ini adalah melakukan analisis peranan jenis nutrisi terhadap peningkatan berat badan bayi prematur dengan masalah defisit nutrisi melalui pendekatan Teori Konservasi Levine. Lima kasus terpilih menunjukkan terjadi masalah keperawatan defisit nutrisi. Pendekatan Teori Konservasi Levine dilakukan dengan menggunakan prinsip konservasi energi, konservasi integritas struktural, konservasi integritas personal, dan konservasi integritas sosial. Hasil pemberian asuhan keperawatan menunjukkan bahwa Teori Konservasi Levine mempengaruhi peningakatan berat bayi prematur. Bayi prematur yang diberikan ASI terjadi peningatan berat badan 10-15 gram per hari, sedangkan bayi prematur yang diberikan susu formula terjadi peningatan berat badan 5-10 gram per hari. Perawat anak dapat mengoptimalkan pemberian ASI kepada bayi prematur untuk meningkatkan berat badan.

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The most common health problems experienced by premature infants is the problem of the digestive system so that weight gain on target cannot be achieved. The purpose of this case study is to analyze the role of nutrients to premature infant weight gain with nutritional deficits through the Levine Conservation Theory approach. Five selected cases indicate a nutritional deficit nursing problem. The Levine Conservation Theory Approach is conducted using energy conservation principles, structural integrity conservation, conservation of personal integrity, and conservation of social integrity. The results of nursing care show that Levine Conservation Theory influences the weighting of premature infants. Premature infants given breastfeeding weight 10 15 grams per day, whereas premature infants given formula milk occured weight gain 5 10 grams per day. Child nurses can optimize breastfeeding for premature babies to gain weight."

"Perpisahan akibat perawatan yang dilakukan pada bayi prematur berpengaruh terhadap proses bonding attachment. Penelitian kualitatif dengan pendekatan fenomenologi deskriptif pada tujuh partisipan ini menggunakan teknik Purpossive Sampling yang bertujuan untuk mengeksplorasi secara mendalam pengalaman orang tua menerima perilaku caring perawat dalam memfasilitasi bonding attachment bayi prematur di Ruang NICU. Pengumpulan data dilakukan dengan wawancara mendalam dan dianalisis dengan metode Colaizzi. Hasil analisis data didapatkan tujuh tema yaitu proses peningkatan pengetahuan, mampu melakukan perawatan terhadap bayinya, respon ibu terhadap tindakan perawatan yang diberikan, termotivasi dalam melakukan perawatan bayi prematur, terpenuhinya kebutuhan bayi selama dilakukan perawatan, keterlibatan dalam asuhan keperawatan dan kepuasan terhadap perawatan. Penelitian ini diharapkan dapat meningkatkan asuhan keperawatan dan bonding attachment pada bayi prematur.

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Separation between parents and premature babies in intensive care unit affects in bonding attachment process. This study was a qualitative research design with descriptive phenomenology approach took 7 participants used Purpossive Sampling Technique. This study aims to explored mother's experience received nursing caring in facilitated bonding attachment of premature babies. Data were collected with indepht interview and analized with Colaizzi method.

The results of data analysis got seven themes: knowledge improving process; capable to cared their babies; mother's respons with nursing care; motivated to cared their premature babies, the premature babies needed was fullfiled well; participated in nursing care; and nursing care satisfaction. The result is expected to be input in improving nursing care and bonding attachment in premature babies."

"ABSTRAKDisertasi ini membahas pengaruh asfiksia pada bayi prematur terhadap kualitas hidup anak usia 2-4 tahun, dengan desain kohort retrospektif. Data asfiksia diperoleh dari catatan medik RSUP Dr. Sardjito, sedangkan kualitas hidup anak dinilai menggunakan PedsQL. Analisis data menggunakan regresi cox.Hasil penelitian menunjukkan ada pengaruh asfiksia terhadap kualitas hidup anak dengan RR: 2,2 (CI: 1.19-4.08). Asfiksia berpengaruh pada fungsi fisik dengan RR: 2,4 (CI: 1.33-4.36) dan fungsi sosial RR: 2,4 (CI: 1.36-4.15) tetapi tidak bermakna pada fungsi emosi RR: 1.4 (CI: 0.86-2.29) dan fungsi sekolah RR: 1.2 (CI: 0.63-2.31).

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ABSTRACT

This dissertation discusses the association of asphyxia in premature infants to the quality of life of children aged 2-4 years with retrospective cohort design. Asphyxia data were obtained from the medical records of Dr. Sardjito hospital, while the quality of life of children data were assessed using PedsQL. Data were analyzed using Cox regression.

The results of study showed strong association of asphyxia to the quality of life of children with RR: 2.2 (CI: 1:19 to 4:08). Risk of asphyxia effects on physical function was RR: 2.4 (CI: 1:33 to 4:36) and on social functioning was RR: 2.4 (CI: 1:36 to 4:15). However, the risk was not significant to the emotional function with RR: 1.4 (CI: 0.86-2.29 ) and school functions RR: 1.2 (CI: 0.63-2.31)."

"Minum merupakan tantangan bagi bayi prematur karena imaturitas dan penyakit yang menyertainya. Bayi prematur yang dinyatakan siap minum seringkali tidak mampu minum. Saat ini belum terdapat tata laksana yang konsisten dan mempertimbangkan kompleksitas proses minum secara komprehensif. Tujuan penelitian ini adalah menentukan berbagai faktor yang memengaruhi ketidakmampuan minum dan membuktikan efektivitas tata laksana metode baru terhadap kemampuan minum bayi prematur.Penelitian dilakukan di lima rumah sakit di Jakarta pada bulan Agustus–November 2021. Studi potong lintang meneliti faktor yang memengaruhi ketidakmampuan minum 120 bayi prematur siap minum usia kehamilan 28–34 minggu, yaitu tonus postural fleksi fisiologis, stabilitas fisiologis, refleks rooting, kemampuan regulasi diri, morbiditas, dan behavioral state. Selanjutnya dilakukan randomized controlled trial (RCT) membandingkan tata laksana metode baru dan konvensional 70 bayi prematur belum mampu minum dari studi potong lintang. Metode baru mencakup therapeutic positioning fleksi fisiologis melalui pembedongan dan intervensi oromotor berupa stimulasi oral, gerakan sinergis three finger jaw control, dan isapan non-nutritif menggunakan empeng khusus. Metode konvensional mencakup pembedongan tradisional, stimulasi oral, dan isapan non-nutritif menggunakan empeng yang biasa digunakan di ruang perawatan. Analisis data studi potong lintang dilakukan dengan uji bivariat menghitung prevalence ratio (PR) dan nilai p; uji multivariat, penentuan titik potong skor faktor risiko ketidakmampuan minum melalui kurva Receiving Operating Characteristic (ROC), serta penentuan sensitivitas dan spesifisitasnya. Uji klinis membandingkan rentang waktu tercapainya kemampuan minum bayi yang diberikan kedua jenis metode. Data dianalisis dengan program STATA versi 14.2 (tingkat kemaknaan p < 0,05).Hasil studi potong lintang menunjukkan regulasi diri sebagai faktor utama yang memengaruhi ketidakmampuan minum bayi prematur dengan PR 1,96 (1,61–3,34; IK 95%) dan p = 0,012, diikuti tonus postural, behavioral state, dan morbiditas (PR 1,91; 1,59; 1,56). Skor faktor risiko ketidakmampuan minum memiliki area under the curve (AUC) sebesar 0,698, titik potong optimal pada skor ≥ 7 dengan sensitivitas 71,4% dan spesifisitas 54%. Hasil uji klinis membuktikan metode baru lebih efektif dibandingkan metode konvensional (4 vs. 7 hari; p = 0,02).Berbagai faktor yang memengaruhi ketidakmampuan minum bayi prematur siap minum adalah regulasi diri, tonus postural, behavioral state, dan morbiditas. Metode baru lebih efektif dibandingkan metode konvensional.

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Feeding for premature infants is a challenge because of their immaturity and comorbidities. Premature infants who are ready to feed are often not able to feed. Current managements have not been consistent and consider the complexity of the feeding process comprehensively. The purpose of this study was to determine various factors influencing feeding inability of premature infants and to verify the effectiveness of a new method management on the premature infants’ feeding ability.

The study was conducted in five hospitals in Jakarta in August–November 2021. A cross-sectional study examined factors influencing the oral feeding inability on 120 ready to feed premature infants born at 28–34 weeks of gestation. Evaluation of feeding inability risk factors included physiological flexion postural tone, physiological stability, rooting reflex, self-regulation ability, morbidity, and behavioral state. Subsequently, a randomized controlled trial (RCT) comparing the new and conventional method was conducted in 70 premature infants who were not able to feed from the cross-sectional study participants. The new method encompasses physiological flexion therapeutic positioning swaddling, and oromotor intervention consisting of oral stimulation, synergic three finger jaw control, and non-nutritive sucking by using a specific pacifier. The conventional method consists of traditional swaddling, oral stimulation, and non-nutritive sucking using the usual pacifier in the nursery room. In the cross-sectional study, bivariate analysis was done to determine the prevalence ratio (PR) and p value; multivariate analysis, Receiving Operating Characteristic (ROC) curve to determine the scoring system cut-off point, as well as its sensitivity and specificity. Clinical trial data analysis compared the new and conventional method effectivity in terms of duration needed to achieve feeding ability in premature infants. STATA version 14.2 was used for data analysis (level of significance p < 0,05).

The results from the cross-sectional study showed that self-regulation had the highest influence of feeding inability with PR 1,96 (1,61–3,34; IK 95%) and p = 0,012, followed by postural tone, behavioral state, and morbidity (PR 1,91; 1,59; 1,56). The feeding inability risk score had an area under the curve (AUC) of 0.698, an optimal cut–off point of ≥ 7, as well as sensitivity of 71,4%, and specificity of 54%. In clinical trials, it was proven that the new method was more effective than the conventional method (4 vs. 7 days; p = 0,02).

Factors influencing feeding inability in premature infants were self-regulation, postural tone, behavioral state, and morbidity. The new method management was more effective than the conventional method."

"Bayi prematur dengan alat bantu nafas ventilasi mekanik memerlukan tindakan bersihan jalan napas. Penelitian menggunakan quasy experiment pada dua kelompok A dan B untuk mengetahui perubahan saturasi sebelum, selama dan setelah tindakan bersihan jalan napas. Kelompok A open suction dan B closed suction masing-masing 30 dan 10 bayi prematur. Analisis menggunakan uji statistik repeated Anova yang dilanjutkan dengan post hoc paired wise comparison. Tindakan bersihan jalan napas menggunakan open suction nilai p kurang 0,001 secara statistik terdapat perbedaan rerata yang bermakna terhadap perubahan saturasi, sedangkan closed suction nilai p kurang 0,001 terdapat perbedaan rerata yang bermakna terhadap perubahan saturasi. Penggunaan alat pengisap lendir closed suction menunjukan keadaan saturasi oksigen lebih stabil, sehingga lebih disarankan untuk tindakan bersihan jalan napas pada bayi prematur. Penggunaan closed suction akan efektif pada keadaan sekret yang encer.

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Premature infant with a mechanical ventilation need airway clearance. The study used quasy experiment in two groups A and B to provide information before and after airway clearance. Group A open suction and B closed suction each of 30 and 10 premature infants. The analysis used the statistical repeated Anova test followed by post hoc paired wise comparison. Airway clearance using an open suction with p.value 0.001, statistically, there is a mean actually oxygen saturation, while closed suction p value of less than 0.001 is the average actually oxygen saturation. The used closed suction shows a more stable oxygen saturation state, more for airway clearance in premature infants. The use of the closed suction will be effective in the state of dilute secretions."