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"Anemia defisiensi zat besi pada ibu hamil dapat diatasi melalui program pemberian Tablet Tambah Darah (TTD). Berdasarkan data Riskesdas tahun 2018, ibu hamil yang mengonsumsi TTD sesuai rekomendasi (90+ tablet) hanya sebesar 38,1%. Beberapa penelitian menyebutkan bahwa faktor-faktor yang memengaruhi ibu hamil tidak patuh mengonsumsi TTD adalah ibu hamil memulai kunjungan ANC pada trimester kedua dan ketiga, melakukan kunjungan ANC kurang dari empat kali, dan mendapatkan pelayanan ANC tidak sesuai standar (<10T). Ketiga faktor tersebut merupakan ukuran dari kualitas kunjungan ANC. Penelitian ini bertujuan untuk mengetahui hubungan antara kualitas kunjungan antenatal care terhadap kepatuhan konsumsi TTD ibu hamil di Indonesia tahun 2017. Desain penelitian ini adalah cross sectional menggunakan data SDKI 2017. Sampel penelitian ini adalah Wanita Usia Subur (WUS) 15-49 tahun yang memenuhi kriteria inklusi sebesar 12.230. Analisis data menggunakan complex sample. Hasil analisis multivariat menunjukan terdapat hubungan antara kualitas kunjungan antenatal care terhadap kepatuhan konsumsi TTD ibu hamil di Indonesia setelah dikontrol status ekonomi, tempat tinggal, dan tenaga pemeriksa hamil. Ibu hamil yang memiliki kualitas kunjungan ANC baik dan cukup memiliki kepatuhan mengonsumsi lebih tinggi dibandingkan ibu hamil yang memiliki kualitas kunjungan ANC kurang dengan nilai OR sebesar 4,3 (95% CI: 3,46-5,37) dan 2,7 (95% CI: 2,27-3,25).

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Iron deficiency anemia among pregnant women can be corrected with iron supplementation programs. According to Riskesdas data in 2018, pregnant women who took iron tablets with the recommendation (90+ tablets) were only 38.1%. Several studies state that factors that influence pregnant women not to comply with taking iron tablets are pregnant women starting ANC visits in the second and third trimesters, visiting ANC less than four times, and getting ANC services that are not up to standard. The third factor is a measure of the quality of ANC visits. This study aims to determine the relationship between the quality of antenatal visits and adherence to iron supplements consumption of pregnant women in Indonesia in 2017. The design of this study was cross-sectional using the 2017 IDHS data. The sample of this study was women of childbearing age 15-49 years who met the inclusion criteria of 12,230. Data analysis used complex sample. The results of the multivariate analysis showed the relationship between the quality of antenatal visits and adherence to iron supplements consumption of pregnant women in Indonesia after controlling for economic status, place of residence, and pregnant examiners. Pregnant women who had high and sufficient quality ANC visits had higher adherence to consumption than pregnant women who had less quality ANC visits with OR values of 4.3 (95% CI: 3.46-5.37) and 2.7 (95% CI: 2.27-3.25)."

"Iron deficiency anemia is the most common nutritional disorder in developing countries and the most at risk population are women of reproductive age, pregnant women and children (DeMaeyer, 1989). UNICEF reported in 1998 that, nearly two billion people are estimated to be anemic, the majority of them were women.

The anemia prevalence in Indonesia is still high and considered as a public health problem. According to the data fiom the National Household Survey (SKRT) in 1995, the average prevalence of iron deficiency anemia among females aged 15-44 years and pregnant women were 48.9 % and 50.9%, respectively. Whereas based on data from the Directorate of Community Nutrition in 1997, 30%-40% among female factory workers as one segment of women at reproductive age suffered &om anemia (Kodyat, 1997)- The study carried out by I-Iusaini et. al (1981) in West Java, Scholz et. al (1997) in Jakarta and Untoro et. al (1998) in Kudus District, Central Java Province showed, that the anemia prevalence among female workers ranged hom 35.5%-50%.;Iron deficiency anemia is the most common nutritional disorder in developing countries and the most at risk population are women of reproductive age, pregnant women and children (DeMaeyer, 1989). UNICEF reported in 1998 that, nearly two billion people are estimated to be anemic, the majority of them were women.

The anemia prevalence in Indonesia is still high and considered as a public health problem. According to the data fiom the National Household Survey (SKRT) in 1995, the average prevalence of iron deficiency anemia among females aged 15-44 years and pregnant women were 48.9 % and 50.9%, respectively. Whereas based on data from the Directorate of Community Nutrition in 1997, 30%-40% among female factory workers as one segment of women at reproductive age suffered &om anemia (Kodyat, 1997)- The study carried out by I-Iusaini et. al (1981) in West Java, Scholz et. al (1997) in Jakarta and Untoro et. al (1998) in Kudus District, Central Java Province showed, that the anemia prevalence among female workers ranged hom 35.5%-50%.;;Iron deficiency anemia is the most common nutritional disorder in developing countries and the most at risk population are women of reproductive age, pregnant women and children (DeMaeyer, 1989). UNICEF reported in 1998 that, nearly two billion people are estimated to be anemic, the majority of them were women.

The anemia prevalence in Indonesia is still high and considered as a public health problem. According to the data fiom the National Household Survey (SKRT) in 1995, the average prevalence of iron deficiency anemia among females aged 15-44 years and pregnant women were 48.9 % and 50.9%, respectively. Whereas based on data from the Directorate of Community Nutrition in 1997, 30%-40% among female factory workers as one segment of women at reproductive age suffered &om anemia (Kodyat, 1997)- The study carried out by I-Iusaini et. al (1981) in West Java, Scholz et. al (1997) in Jakarta and Untoro et. al (1998) in Kudus District, Central Java Province showed, that the anemia prevalence among female workers ranged hom 35.5%-50%."

"Vitamin A diketahui dapat memodulasi sel T regulator (Treg) sehingga IL-10 mengalami penurunan Tujuan penelitian ini mengetahui pengaruh pemberian vitamin A dosis rendah dalam meregulasi respons imun sitokin anti-inflamasi (IL-10) pada ibu hamil sehingga terjadi penurunan jumlah telur per gram tinja (TPG) infeksi A.lumbricoides. Penelitian ini menggunakan data sekunder ibu hamil yang terinfeksi A. lumbricoides di Kalibaru, Jakarta Utara. Terdapat dua kelompok data, vitamin A (18 ibu hamil) dan plasebo (21 ibu hamil). Semua pemeriksaan tinja dan IL-10 dalam serum dilakukan sebelum dan sesudah intervensi. Diagnosis askariasis dengan pemeriksaan tinja menggunakan metode Kato-Katz, dan pemeriksaan IL-10 dalam serum dengan metode ELISA. Sebelum intervensi, rerata konsentrasi IL-10 pada kelompok vitamin A 48,1± 34,2 pg/mL dan plasebo 37,6 ± 26,1 pg/mL. Setelah intervensi, terdapat perbedaan bermakna (p=0.006) antara rerata perubahan konsentrasi IL-10 pada kelompok vitamin A (-2,5±38,88 pg/mL) dengan plasebo (-1,7±27,18 pg/mL). Selain itu, perubahan rerata perubahan TPG pada kelompok vitamin A berbeda bermakna (p=0,000) dengan kelompok plasebo. Perubahan IL-10 tersebut berdampak terjadi perubahan TPG A. lumbricoides pada kelompok vitamin A. Untuk mengurangi intensitas infeksi A. lumbricoides pada ibu hamil diperlukan vitamin A untuk menurunkan IL-10.

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Vitamin A has been known for modulating T regulator cells so that it may decrease interleukin 10 (IL-10). The aim of this study was to know the effect of low doses vitamin A supplementation on regulating immune responses of antiinflamation cytokines (IL-10) in pregnant women to decrease Ascaris lumbricoides egg in each gram of stool (EPG).

This study used secondary data from pregnant women infected by A.lumbricoides in Kalibaru, North Jakarta. There were 2 groups, one given vitamin A supplementation (18 pregnant women) and the other one with placebo (21 pregnant women). All of the stool and IL-10 serum samples were examined at before and after intervention. Diagnosis of ascariasis was established by stool sample examination using Kato-Katz method and levels of IL-10 by ELISA. Before intervention, mean of IL-10 level in vitamin A group was 48.1± 34.2 pg/mL and placebo 37.6 ± 26.1 pg/mL.

After intervention, there was significant differentiation (p=0.006) between alteraion of mean IL-10 level in vitamin A (2.5±38.88 pg/mL) and placebo (1.7±27.18 pg/mL). In addition, alteration mean of EPG was significant differentiation (p=0.000). Alteration of mean IL-10 level affected on alteration A. lumbricoides EPG especially in vitamin A group. This study showed that IL-10 may play a role of decreasing A. lumbricoides egg per gram of stool in pregnant women."

"Asam folat adalah salah satu mikronutrien yang dibutuhkan pada masa kehamilan, khususnya pada trimester awal. Berdasarkan Riskesdas, kebutuhan asupan asam folat pada ibu trimester awal adalah 600 mcg. Pada ibu hamil defisiensi folat sering terjadi sehingga memberikan banyak efek pada masa kehamilan, seperti berat badan lahir rendah, kejadian defek tabung neural, dan lain-lain. Tujuan dari penelitian yaitu untuk mengetahui apakah terdapat korelasi antara asupan asam folat dengan kadar folat dalam darah. Penelitian menggunakan desain cross sectional dengan menggunakan 62 sampel yang berasal dari data sekunder sebuah penelitian primer dengan subjek wanita hamil trimester pertama di rumah sakit yang berlokasi di Jakarta. Data asupan asam folat didapatkan dari FFQ, sedangkan untuk kadar folat darah sewaktu didapatkan melalui pengukuran dengan FBP. Pengolahan data yang digunakan dengan menggunakan software SPSS versi 20 Mac OSX dengan menggunakan uji Kolmogorov-Smirnov dan uji Spearman's.Pada penelitian ditemukan angka asupan folat yang rendah 25,8% dengan median 23,75 (nilai maksimum 32,4 dan minimum 17,3), namun kadar folat serum dalam darah normal bahkan berlebih pada subjek dengan median 19,34 (nilai minimum 11,67 dan maksimum 34,6). Berdasarkan penelitian yang sudah dilakukan tidak ditemukan adanya korelasi antara asupan asam folat dengan kadar folat dalam darah dengan nilai (p=0,201) dan nilai r yang rendah (r=0,165).

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Folic acid is one of the micronutrients needed during the term of pregnancy, especially in the first smester. Based on Riskesdas, folic acid total intake in the first term pregnancy is 600 mcg. In pregnant women folate deficiency often occurs that gives a lot of effect on pregnancy, such as low birth weight is low, the incidence of neural tube defects, and others. The aim of this study was to determine whether there is a correlation between the intake of folic acid and folate levels in the blood.

The study used cross sectional design using 62 samples derived from secondary data from a primary research with the subject of the first trimester pregnant women in hospitals are located in Jakarta. The measurement used for folic acid intake by using food frequency questionnare (FFQ) and FBL used for measuring folate serum in the blood . Processing of the data used by using SPSS software version 20 Mac OSX using the Kolmogorov-Smirnov test and Spearman's test.

The study found that low folate intake figure of 25.8% with a median of 23.75 (32.4 maximum value and minimum 17.3) and the median of folate serum level is 19,34 (a minimum value of 11, 67 and a maximum of 34.6). Based on research that has been done there is no correlation between folate intake and folate serum level in the first trimester of pregnancy with values (p = 0.201) and a lower value of r (r = 0.165)."

"Prevalensi risiko kurang energi kronis (KEK) pada ibu hamil di Indonesia mengalami peningkatan berdasarkan data Riskesdas tahun 2007 dan 2013. Kondisi ini penting diperhatikan karena kurang energi kronis pada ibu hamil akan memberikan dampak yang buruk tidak hanya pada tubuh ibu namun juga janin yang dikandungnya. Proporsi risiko KEK memiliki sebaran yang berbeda-beda terkait karakteristik ibu hamil, misalnya pekerjaan, pendidikan, dan usia kehamilan. Selain itu, asupan nutrisi tentu menjadi faktor penting yang memengaruhi status nutrisi ibu hamil. Penelitian ini dilakukan untuk mengetahui hubungan antara prevalensi risiko KEK pada ibu hamil di Jakarta dengan pekerjaan, pendidikan, usia kehamilan, dan asupan makronutrien. Potong lintang merupakan desain penelitiannya dengan jumlah subjek sebanyak 56 orang ibu hamil usia 20-35 tahun di Jakarta. Pengukuran lingkar lengan atas (LiLA) digunakan untuk menilai risiko KEK (<23,5cm). Data asupan makronutrien diperoleh dengan menggunakan metode 24-hour food recall. Data pendidikan, pekerjaan, dan usia kehamilan diperoleh dengan menggunakan kuesioner. Hasil penelitian ini menunjukan bahwa prevalensi risiko KEK mencapai 10,7%. Berdasarkan uji fisher tidak menunjukan adanya hubungan yang signifikan antara risiko KEK pada ibu hamil di Jakarta dengan pekerjaan, pendidikan, asupan makronutrien, asipan energy, dan usia kehamilan. Terdapat beberapa faktor yang tidak diteliti pada penelitian ini antara lain usia saat hamil dan aktivitas fisik.

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The prevalence of chronic energy deficiency (CED) on pregnant women in Indonesia have increased based on data Riskesdas 2007 and 2013. This condition is important to note because chronic energy deficiency in pregnant women will have a negative effect for both mother and fetus. The proportion of CED has different based on occupation, education, and gestational age of pregnant women. In addition, nutrition is certainly an important factor affecting the nutritional status of pregnant women.

This study was conducted to determine the relationship between the prevalence of CED in pregnant women in Jakarta and occupation, education, pregnancy / trimester of pregnancy, and macronutrient intake. Is a cross-sectional study design with a number of subjects as much as 56 pregnant women aged 20-35 years in Jakarta.Measurement mid upper arm circumference (MuAC) is used to assess the risk of CED (<23.5 cm). Macronutrient intake data is obtained by using a 24-hour food recall. Data of education, occupation, and trimester of pregnancy obtained using a questionnaire.

These results indicate that the prevalence of CED reached 10.7%. Based fisher test showed no significant association between the risk of CED in pregnant women in Jakarta and her occupation, education, macronutrient intake, energy intake, and trimester of pregnanc. There are several factors which are not examined in this study include age and physical activity."

"Saat hamil terjadi peningkatan kebutuhan berbagai mikronutrien salah satunya adalah seng. Asupan seng yang adekuat selama kehamilan berperan dalam kesehatan janin. Namun, defisiensi seng sebagai akibat dari asupan yang tidak adekuat atau bioavailabilitas seng yang rendah masih menjadi masalah bagi negara berkembang seperti Indonesia. Penelitian ini bertujuan untuk mengetahui bagaimana hubungan antara asupan seng dalam diet dengan kadar seng serum ibu hamil trimester satu dalam rangka menurunkan angka defisiensi seng di Indonesia. Penelitian ini menggunakan studi potong lintang dengan jumlah subjek penelitian adalah 62 ibu hamil trimester satu dipilih melalui simple random sampling. Dari penelitian ini diperoleh nilai media asupan seng pada ibu hamil trimester satu adalah 2.26 (0.3-51.8) mg/hari. Sebanyak 90.3% subjek penelitian tidak memenuhi asupan seng sesuai rekomendasi AKG. Nilai median kadar seng serum ibu hamil trimester satu dalam penelitian ini adalah 61.29 (39.0-102.0) ug/dL. Terdapat korelasi negatif lemah dan bermakna secara statistik antara kadar seng serum dan asupan seng dalam diet ibu hamil trimester satu (r = -0.266, p = 0.037). Dari penelitian ini dapat disimpulkan bahwa kadar seng serum perlu dipertahankan dalam interval normal, antara lain dengan kecukupan asupannya dari makanan dan suplementasi, khususnya selama masa kehamilan

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There is an increasing need in micronutrient including zinc as adequate zinc intake plays role in fetal health. Nevertheless, zinc deficiency as a result of insufficient intake or low bioavailability is a problem in developing countries including Indonesia. This research observe the association between zinc intake and the serum level of zinc in first trimester pregnancy with the goal to reduce zinc deficiency in Indonesia. There are 62 subjects of first trimester pregnant women and this study is done using cross-sectional design with simple random sampling.

It is found that the median of zinc intake in first trimester pregnant women is 2,26 (0,3-51,8) mg/day. This research found that 90,3% of subjects did not fulfill the recommended dietary allowances for zinc intake. The median serum level of zinc in first trimester pregnant women is 61,29 (39,0-102,0) ug/dL. There is weak inverse correlation that is significant statistically between zinc serum level and zinc intake in first trimester pregnant women (p = 0,037, r = -0,266). It is concluded that zinc serum level must be maintained in the normal interval, such as an adequate intake and supplementation, especially during pregnancy"

"Masih tingginya AKI di Indonesia mencerminkan bahwa intervensi untuk menurunkan AKI masih belum berjalan maksimal. Intervensi tersebut melalui antenatal care. Sayangnya, masih terdapat perbedaan cakupan antenatal care K6 yang cukup besar antara perkotaan dan pedesaan Indonesia. Cakupan K6 ditemukan lebih tinggi pada wilayah perkotaan (56.1%) bila dibandingkan dengan wilayah pedesaan (41.9%). Penelitian ini bertujuan untuk mengidentifikasi determinan kunjungan antenatal care (K6) pada ibu hamil di wilayah perkotaan dan pedesaan Indonesia. Sampel penelitian ini adalah seluruh wanita usia subur yang tinggal di Indonesia serta memenuhi kriteria inklusi dengan jumlah sampel 6790 responden untuk wilayah perkotaan dan 7013 responden untuk wilayah pedesaan. Penelitian ini menggunakan uji chi square dan regresi logistik ganda dalam analisisnya. Hasil penelitian ini menunjukkan bahwa determinan kunjungan antenatal care (K6) pada wilayah perkotaan dan pedesaan Indonesia tahun 2017, yaitu usia, paritas, tingkat pendidikan ibu, pengetahuan terkait komplikasi kehamilan, indeks kekayaan rumah tangga, dukungan suami/pasangan, dan pengambil keputusan terkait perawatan kesehatan ibu. Paparan dengan media massa hanya berhubungan dengan kunjungan antenatal care (K6) pada wilayah perkotaan saja. Sementara, tempat/fasilitas pelayanan kesehatan hanya berhubungan dengan kunjungan antenatal care (K6) pada wilayah pedesaan saja. Tingkat pendidikan ibu menjadi variabel yang berhubungan paling dominan dengan kunjungan antenatal care (K6) pada wanita hamil di wilayah perkotaan dan pedesaan Indonesia.

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The still high MMR in Indonesia reflects that interventions to reduce MMR have not run optimally. The intervention is through antenatal care. Unfortunately, there are still quite large differences in coverage of K6 antenatal care between urban and rural Indonesia. K6 coverage was found to be higher in urban areas (56.1%) when compared to rural areas (41.9%). This study aims to identify the determinants of antenatal care (K6) visits to pregnant women in urban and rural areas of Indonesia. The sample for this study were all women of childbearing age living in Indonesia and meeting the inclusion criteria with a sample size of 6790 respondents for urban areas and 7013 respondents for rural areas. This study uses the chi square test and multiple logistic regression in its analysis. The results of this study indicate that the determinants of antenatal care visits (K6) in urban and rural areas of Indonesia in 2017, namely age, parity, education level of the mother, knowledge related to pregnancy complications, household wealth index, husband/spousal support, and decision makers regarding care mother's health. Exposure to the mass media is only related to antenatal care (K6) visits in urban areas. Meanwhile, health service places/facilities are only related to antenatal care (K6) visits in rural areas. Maternal education level is the most dominant variable related to antenatal care (K6) visits to pregnant women in urban and rural areas of Indonesia."

"Gangguan perkembangan pervasif (GPP) merupakan kelompok gangguan yang ditandai dengan terlambatnya perkembangan keterampilan fungsional dalam sosialisasi, komunikasi, bahasa dan fungsi motorik.Prevalensi GPP dari tahun ke tahun semakin meningkat.Berbagai faktor diduga berkaitan dengan kejadian GPP termasuk faktor kehamilan ibu. Penelitian ini bertujuan untuk mengetahui hubungan antara faktor kehamilan dengan GPP. Penelitian ini menggunakan desain kasus kontrol dengan melibatkan 52 anak dengan GPP (44 laki-laki, 8 perempuan) dan 156 anak tanpa GPP sebagai kontrol (132 laki-laki, 24 perempuan) dengan umur rata-rata kelompok kasus dan kontrol 7,3 tahun, untuk menganalisis enam faktor kehamilan ibu yang mungkin berpengaruh terhadap kejadian GPP. Data diperoleh dari wawancara terhadap ibu kandung masing-masing anak. Hasil penelitian menunjukkan bahwa kebiasaan ibu merokok saat hamil berhubungan secara bermakna dengan GPP (OR = 6,417; 95% CI 1,140-36,12; p = 0,035). Demikian pula dengan riwayat infeksi (OR = 4,250; CI 3,319-5,443; p = 0.004) dan riwayat depresi ketika hamil (OR = 4,508; 95% CI 2,015-10,084; p = 0,001). Riwayat ibu sebagai perokok pasif, kebiasaan meminum alkohol, dan konsumsi obat-obatan selama hamil tidak berhubungan secara bermakna dengan GPP. Disimpulkan bahwa kebiasaan ibu merokok, riwayat infeksi, dan riwayat depresi saat hamil merupakan faktor risiko penting Gangguan Perkembangan Pervasif.

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Pervasive developmental disorder (PDD) is a group of developmental disorders that is characterized by delays in the development of functional skills in socialization, communication, language and motor function. Prevalence of PDD is increasing every year. Various factors are suspected to have correlation with PDD including maternal pregnancy factors.

This study aims to determine the relationship between pregnancy factors with PDD. This study used case -control design involving 52 children with PDD (44 males and 8 females) and 156 children without PDD as controls (132 men and 24 women) with an average age of cases and controls 7.3 years , to analyze the correlation between six maternal pregnancy factors that may affect the incidence of PDD. Data were obtained from interviews with the biological mother of each child.

The results showed that maternal smoking habits during pregnancy significantly correlate with PDD (OR = 6.417; 95% CI 1.140 - 36.12; p = 0.035). As well as a history of infection (OR = 4.250; CI 3.319 -5.443; p = 0.004) and a history of depression during pregnancy (OR = 4.508; 95% CI 2.015 -10.084; p = 0.001). Meanwhile, maternal history of passive smoking, alcohol drinking habits, and consumption of drugs during pregnancy was not significantly associated with PDD.

In conclusion, maternal smoking, history of infection and a history of depression during pregnancy have an important role as risk factors ofPervasive Development Disorders."

"C-Reactive Protein merupakan protein penanda biologis yang jumlahnya akan meningkat ketika terjadi proses inflamasi di dalam tubuh. Pada kehamilan, proses inflamasi merupakan proses fisiologis namun tentunya dalam batas normal. Status gizi maternal dipercaya memiliki hubungan dengan proses inflamasi yang terjadi. Penelitian ini bertujuan untuk melihat hubungan antara kadar high-sensitivity C-Reactive Protein (hs-CRP) pada ibu hamil trimester satu dengan indeks massa tubuh. Penelitian ini dilakukan dengan metode studi potong lintang dengan jumlah subjek penelitian 62 responden yang dipilih berdasarkan sistem simple random sampling. Dari penelitian ini didapatkan hasil median kadar hs-CRP adalah 2,95 mg/L (0,30-35,30 mg/L). Penelitian ini menggunakan cut-off kadar hs-CRP 5 mg/L dan didapatkan hasil 32,3% subjek memiliki kadar yang tinggi. Indeks massa tubuh ibu hamil trimester pertama ini memiliki nilai rerata 23,68±3,73 kg/m2. Data kemudian dicari korelasinya dengan uji Pearson. Terdapat korelasi sedang positif antara kadar hs-CRP dengan indeks massa tubuh ibu hamil trimester satu (r = 0,435, p = < 0,001). Dapat disimpulkan bahwa semakin tinggi nilai indeks massa tubuh, maka semakin tinggi kadar hs-CRP pada ibu hamil trimester satu.

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C-Reactive Protein (CRP) is a biomarker protein which increases during inflammation. During pregnancy, there is a physiologic amount of inflammation which increases CRP. Maternal nutrition status is known to be associated with the inflammatory process and pregnancy outcome. The objective of this study was to find the normal value of high-sensitivity C-Reactive Protein (hs-CRP) in first trimester pregnancy and its association with body mass index. This study used cross-sectional design with 62 first trimester pregnant women as subjects. The subjects were chosen using simple random sampling method.

It was found that the median serum level of hs-CRP in the subjects was 2.95 mg/L (0.30-35.30 mg/L). The cut-off point of hs-CRP level in this study was 5 mg/L. There were 32.3 % subjects who had higher hs-CRP value. The mean body mass index was 23.68±3.73 kg/m2. Pearson analysis demonstrated medium correlation between the level of hs-CRP and body mass index in first trimester pregnant women (r = 0.435, p = < 0.001). In conclusion, higher body mass index was associated with the higher hs-CRP level in first trimester pregnant women."

"Angka Kematian Neonatal AKN merupakan salah satu indikator dalam menentukan derajat kesehatan ibu dan anak. Data WHO menunjukkan AKN Indonesia sebesar 13,7 dan SDKI 2012 menyatakan sebesar 19, yang mana memilki kontribusi terhadap 59 kematian bayi. AKB di tahun yan sama sebesar 32. Kondisi selama kehamilan menjadi faktor penyebab umum kematian neonatal, sehingga program pelayanan kesehatan ibu hamil menjadi penting dalam menurunkan AKN, seperti pemberian tablet besi dan suntik anti tetanus. AKN disebabkan oleh beberapa hal, satu diantaranya adalah BBLR. Penelitian ini bertujuan untuk mengetahui apakah terdapat asosiasi antara konsumsi tablet tambah darah dengan kejadian BBLR dan pada konsumsi keberapa akan berpengaruh terhadap penurunan risiko BBLR. Didapatkan dari analisis chi square bahwa konsumsi tablet tambah darah sesuai dengan anjuran pemerintah yaitu minimal 90, tidak menunjukan adanya hubungan, dengan p value= 0,415 dan nilai OR 1,072 95 CI 0,8441,366 . Pun setelelah dikontrol dengan variabel usia ibu melahirkan, status sosial dan ekonomi, pendidikan ibu, paritas dan kehamilan ganda, tetap menunjukkan asosiasi negatif. Peneliti mencoba mengubah cut off menjadi 150, maka didapatkan konsumsi >150 asosiasi menunjukan positif p value= 0,032 dan OR 1,372 95 CI 1,027-1,833 . Setelah dilakukan analisis dengan memasukkan variabel kontrol, asosiasi yang ditunjukkan menjadi negatif dan nilai OR menunjukan bahwa konsumsi tablet >150 memiliki 0,8 odds lebih kecil untuk terkena BBLR. Sehingga perlu ibu hamil perlu mengonsumsi secara rutin tablet tambah darah yang diberikan oleh petugas kesehatan setempat setidaknya selama 5 bulan lebih dalam rangka menurunkan risiko terjadinya BBLR.

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Neonatal mortality rate NMR is one of inidicators that determine the maternal and child health. WHO shows that NMR in Indonesia is 13,7 and SDKI 2012 states 19, which has contribution to 59 infant mortality. Infant Mortaliry Rates is 32 at the same year. Bad conditions while mother was pregnant are common cause of neonatal mortality, so maternal health care programs are important to reduce NMR, such as iron tablets and anti tetanus injection. NMR is caused by several things, on of them is Low Birth Weight LBW. This research aims to know the association between iron tablets and the newborns with LBW and which consumption the risk of newborns with low weight will be decrease. After analysed with chi square consumption that government recommendation at least 90 doesnt show any relationship with p value 0,415 and OR 1,072 95 CI 0,8441,366. Even after controlled by maternal ages, wealth index, maternal education, parity, and multiple pregnancy. Researchers tried to convert the cut off to 150, and the result shows positive p value 0,032 and OR 1,327 95 CI 1,027 1,833 . After controls variables in, the association became negative with OR shows that consumption 150 has 0,8 odds smaller to LBW. So, pregnant women should consume the iron tablets routinely at least 5 months, better more, to reduce the risk of LBW."