Hasil Pencarian  ::  Simpan CSV :: Kembali

"Latar Belakang:Kanker payudara merupakan kanker dengan jumlah tertinggi pada perempuan di dunia. Meningkatnya angka ketahanan hidup pasien kanker payudara, membuat meningkatnya insiden terjadinya limfedema diakibatkan komplikasi dari Modified Radical Mastectomy(MRM). Belum diketahui apakah ada pengaruh dilakukannya flap jaringan di daerah diseksi kelenjar getah bening pada kanker payudara dengan perbaikan aliran limfe pada daerah tersebut. Tujuan dari penelitian ini adalah mengetahui adanya regenerasi limfatik pada flap jaringan pasien kanker payudara pasca mastektomi dan diseksi aksila.Metode Penelitian: dilakukan penelitian menggunakan desain kuasi eksperimen pada semua pasien kanker payudara yang dilakukan Modified Radical Mastectomy (MRM) dan diseksi aksila dengan menggunakan flap untuk mengurangi kejadian limfedema pasca operasi. Data diambil pada periode januari 2018 sampai Mei 2019Hasil : Terdapat 32 pasien kanker payudara pasca tindakan MRM dan diseksi aksila (16 pasien dengan flap dan 16 pasien tanpa flap). Dari 16 pasien yang dilakukannya flap, terdapat 14 pasien yang mengalami regenerasi limfatik (87,5%) dan 2 pasien yang tidak mengalami regenerasi limfatik (12,5%) pasca pemasangan flap jaringan pada pasien MRM. Terdapat hubungan antara penggunaan flap (p = 0,049 dengan OR 95%CI 5,43 (2,22-32,2)) dan usia (p = 0.042 dengan OR 95%CI0,2 (0,03-0,95))terhadap regenerasi limfatik.Kesimpulan : Terdapat hubungan yang berbeda bermakna antara flap jaringan dengan tanpa flap pada daerah diseksi kelenjar limfe dengan regenerasi limfatik pada daerah tersebut. Tidak terdapat hubungan berbeda bermakna antara komorbid, riwayat radiasi, indeks masa tubuh, stadium TNM, terhadap regenerasi limfatik.

---

Background : Breast cancer is the most common cancer in women in the world. Increased survival rates of breast cancer patients, making the increased incidence of lymphedema caused by complications from Modified Radical Mastectomy (MRM). It is not known yet whether there is an effect of doing tissue flap in the area of ​​lymph node dissection in breast cancer with improved lymph flow in the area. The purpose of this study was to determine the presence of lymphatic regeneration in tissue flap of breast cancer patients after mastectomy and axillary dissection.

Research Method : Conducted a study using quasi-experimental design in breast cancer patients with MRM and axillary dissection alone or by using a flap to reduce the incidence of postoperative lymphedema. Data is taken from January 2018 to Mei 2019.

Results : There were 32 breast cancer patients after MRM and axillary dissection (16 patients with flaps and 16 patients without flap). Of the 16 patients who were replaced by flaps, 14 patients needed lymphatic regeneration (87,5%) and 2 patients who did not need lymphatic regeneration (12,5%) after tissue flaps procedure in MRM patients. There is a relationship between the use of flap (p = 0.049 with OR 95% CI 5,43 (2,22-32,2)) and age (p = 0.042 with OR 95% CI 0,2 (0,03-0,95)) to lymphatic regeneration.

Conclusions : There is a significantly different relationship between tissue flaps and without flaps in the area of ​​lymph node dissection with lymphatic regeneration in the area. There is no significant difference between comorbidities, radiation history, body mass index, TNM stage, and lymphatic regeneration."

"ABSTRAKKanker payudara adalah kanker pada jaringan payudara. Kanker ini merupakan kankeryang paling umum diderita wanita. Pengalaman dan pengobatan kanker tersebutmempunyai pengaruh yang besar dalam kualitas hidup pasien, seperti kelemahan,nausea dan nyeri. Efek samping atau keluhan dari kanker dan pengobatannya cenderungmeningkat selama perawatan dan dapat menetap selama berbulan-bulan atau bertahuntahun.Untuk mencapai proses penyembuhan dan pemulihan yang baik pada pasienkanker payudara pasca mastektomi perlu adanya manajemen nyeri yang tepat. Penelitianini bertujuan mengidentifikasi pengaruh latihan fisik terhadap nyeri pada pasien kankerpayudara pasca mastektomi di RSUD Dr. Achmad Mochtar Bukittinggi. Desainpenelitian ini adalah quasi eksperiment, khususnya non-equivalent control group denganpre dan post test. Sampel berjumlah 30 orang (15 orang kelompok intervensi yangdiberikan 7 hari latihan fisik ditambah analgesik dan 15 orang kelompok kontrol yangdiberikan terapi standar analgesik), yang diambil dengan metode non probabilitysampling jenis consecutive sampling. Evaluasi tingkat nyeri dilakukan setiap hari baikpada kelompok intervensi maupun kelompok kontrol. Hasil penelitian diperoleh adanyapenurunan tingkat nyeri setiap harinya, baik pada kelompok intervensi maupun kelompokkontrol. Penurunan yang lebih besar terjadi pada kelompok intervensi (p=0,000), artinyalatihan fisik pada pasien kanker payudara pasca mastektomi dapat berpengaruh terhadappenurunan tingkat nyeri. Rekomendasi hasil penelitian ini perlu adanya penelitian lanjutdengan jumlah sampel yang lebih besar dan dilanjutkan dengan perawatan di rumah sertadapat di jadikan salah satu intervensi keperawatan dalam menangani manajemen nyeripasca mastektomi.

---

ABSTRACTBreast cancer is one of the common types of cancer among women. The trajectory of theexperience for having the disease and its trestment are believed to produce a big effect onthe quality of life of the patients. The experiences such as weaknesses, nauseated, andpain have to be through by the patients on the daily bases. This side effects andcomplaints created form the cancer and its therapy tend to increase during hospitalizationand can be pertinent for months or ever years. Therefore, to achieve a better healing andrecovery processes for the breast cancer patients especially post mastectomy requires theright pain management.The purpose of this study is to identify the effect of physical exercise on pain perceivedby the breast cancer patient after mastectomy at Dr Achmad Mochtar General Hospital,Bukittinggi. The design was a quasi experimental using a non-equivalent control groupwith pre and post test approach. There was 30 subjects participated in the study dividedtwo groups (the intervention group was provided with analgesic and seven days physicalexercise; and, the control group was provided with analgesic only); 15 subjects for eachgrup. A non probability sampling method-consecutive type was utilized to gather thesubjects. The pain was evaluated each day to both groups.The findings of the study demonstrated that there is a daily pain reduction between bothgroups. Further, the comparison of the pain reduction between these two group leads tothe bigger pain reduction in the intervention group compared to the control group(p=0.000). This finding showed that the physical exercise provided to the postmastectomy-breast cancer patients has a significant effect to reduce the pain level. Thiswith home care; also this finding can be used as a foundation to involve physicalexercise as on of the nursing intervention in managing post mastectomy pain commonlyexperienced by breast cancer patients."

"

Kanker payudara merupakan penyakit kanker yang paling banyak terjadi pada wanita. Edukasi self management dengan media booklet digital dan video pada pasien kanker payudara pasca mastektomi diperlukan untuk meningkatkan keyakinan dalam melakukan pengelolaan kesehatan mandiri dan mendukung keberlangsungan pengobatan selanjutnya, yang menjawab tantangan pergeseran sistem pelayanan kesehatan ke pelayanan berbasis digital. Penelitian bertujuan mengetahui pengaruh edukasi self management dengan media booklet digital dan video terhadap self efficacy. Tempat penelitian  RSUP DR Sardjito Yogyakarta,pada bulan Maret hingga Mei 2024, menggunakan quasi experiment pre post desing with comparison group. Jumlah sampel 30 kelompok intervensi dan 30 kelompok kontrol diambil dengan teknik purposive sampling.Data dianalisis menggunakan T-test, menunjukkan peningkatan self efficacy yang significan pada kelompok intervensi p = 0,000 (<0,05) sedangkan kelompok kontrol tidak terjadi peningkatan yang significan p=0,967. Oleh karena itu, edukasi self management dengan media booklet digital dan video dapat digunakan untuk meningkatkan keyakinanan dalam perawatan mandiri pasien kanker payudara pasca mastektomi.

---

Breast cancer is the most common cancer in women. Self-management education using digital booklets and video media for post-mastectomy breast cancer patients is needed to increase confidence in carrying out independent health management and support the continuation of subsequent treatment, which answers the challenges of shifting the health service system to digital-based services. The research aims to determine the effect of self-management education using digital booklets and video media on self-efficacy. The research site at RSUP DR Sardjito Yogyakarta, from March to May 2024, used a quasi experimental pre post design with comparison group. The total sample of 30 intervention groups and 30 control groups was taken using a purposive sampling technique. Data were analyzed using the T-test, showing a significant increase in self-efficacy in the intervention group p = 0.000 (<0.05) while there was no significant increase in the control group p= 0.967. Therefore, self-management education using digital booklets and videos can be used to increase confidence in self-care for breast cancer patients after mastectomy."

"ABSTRAKKanker payudara merupakan tumor ganas pada jaringan payudara yang bersifat invasif dan paling sering terjadi pada wanita. Mastektomi adalah salah satu operasi kanker payudara yang mengangkat jaringan payudara beserta otot pektoralis dan nodus limfe aksila. Komplikasi lebih lanjut pada pasien yang menjalani operasi mastektomi dan diseksi nodus limfe aksila yaitu terjadinya limfedema. Studi kasus ini dilakukan untuk menganalisis intervensi keperawatan berupa latihan mobilisasi lengan pada pasien kanker payudara pasca operasi mastektomi dan diseksi nodus limfe aksila. Hasil intervensi menujukkan adanya pengaruh signifikan dari pemberian latihan mobilisasi lengan pada pasien yang ditandai dengan penurunan tingkat nyeri dan peningkatan kekuatan otot, serta tidak adanya kemerahan, edema, kesemutan dan kekakuan pada lengan. Rekomendasi dari studi kasus ini adalah perawat perlu mengetahui tanda dan gejala limfedema pada pasien kanker payudara, sehingga komplikasi pasca operasi mastektomi dan diseksi nodus limfe aksila dapat dicegah dan kualitas hidup pasien dapat meningkat.

---

ABSTRACTBreast cancer is an invasive malignant tumor in breast tissues which commonly occurred in women. Mastectomy is a breast cancer surgery which breast tissues alongside pectoral muscles and axillary lymph nodes are dissected. Further complications in patients undergoing mastectomy and dissection of axillary lymph nodes is the occurrence of lymphedema. This case study was conducted to analyze nursing intervention, which is arm mobilization exercise, in post operative mastectomy and axillary lymph nodes dissection patient. The results of the intervention showed the significant effect of arm mobilization exercise in patient proven by decreased pain levels, increased muscle strength, and absence of redness, edema, tingling and stiffness in the arms. This study recommend nurses need to know the signs and symptoms of lymphoedema in breast cancer patients. Therefore, post operative complications of mastectomy and axillary lymph node dissection can be prevented and patients rsquo quality of life may increase."

"ABSTRAKLatar Belakang. Tindakan pembedahan radikal pada pasien dengan kanker seringkali menyebabkan komplikasi limfedema. Limfedema dapat diatasi dengan operasi transfer jaringan atau rekonstruksi limfatik. Penelitian ini bertujuan untuk membuktikan adanya pembentukan pembuluh limfe baru dengan penambahan flap jaringan pasca diseksi kelenjar limfe, dilihat dari peningkatan ekspresi VEGF-C, infiltrasi makrofag, dan pembentukan fibrosis.Metode. Penelitian ini merupakan penelitian eksperimental pada 20 ekor tikus Sprague Clawley jantan berumur 8-12 minggu, yang dibagi rata kedalam tiap kelompok perlakuan, di Animal House Skill Lab Fakultas Kedokteran Universitas Indonesia pada Januari-Maret 2018. Tiap tikus akan menjalani diseksi, kemudian diacak untuk menerima flap jaringan maupun hanya diseksi inguinal, dan dievaluasi setelah 2 bulan. Pemeriksaan histopatologi dilakukan pada akhir penelitian untuk menilai pembentukan fibrosis dan dilanjutkan pemeriksaan immunohistokimia. Analisis data dilakukan dengan program SPSS 20.0.Hasil. Sebanyak 8 tikus 88.9 yang menerima flap jaringan menunjukkan hasil positif pada tes methylene blue dibandingkan 2 tikus 22.2 pada kelompok kontrol p < 0.05 . Pada 18 tikus tersebut, pewarnaan HE juga menunjukkan adanya pembentukan jaringan ikat pembuluh yang lebih lebar pada tikus yang diberi perlakuan, meski tidak signifikan secara statistik. Pemeriksaan immunohistokimia juga menunjukkan ekspresi VEGF-C yang lebih jelas dengan dominasi warna coklat pada tikus perlakuan p < 0.05 . Ekspresi protein CD68 juga lebih jelas pada tikus perlakuan meski perbedaannya tidak signifikan.Kesimpulan. Penambahan flap jaringan dapat membantu memperbaiki aliran limfa yang dibuktikan dengan peningkatan aliran limfe dan ekspresi VEGF-C.

---

ABSTRACT

Background. Radical surgeries for patients with cancer often cause lymphedema complications. Lymphedema may be solved with tissue transfer or lymphatic reconstruction surgery. This research aims to prove new formations of lymphatic vessels by the addition of tissue flap post dissection of lymphatic vessels, marked by increased expression of VEGF-C, macrophage infiltration, and fibrosis formation.Methods. This is an experimental study on 20 male Sprague Clawley mice aged 8-12 weeks, divided evenly for each experiment group, at Animal House Skill Lab Faculty of Medicine Universitas Indonesia from January-March 2018. Each mouse underwent dissection, randomized for flap addition or only inguinal dissection, and evaluated after 2 months. Histopathologic assessment was conducted at the end of study period to evaluate fibrosis formation and followed by immunohistochemistry analysis. Data analysis was conducted with statistical program SPSS 20.0Results. 8 mice 88.9 , which received tissue flap showed positive results on methylene blue test compared to 2 mice 22.2 from control group p < 0.05 . From the 18 mice, HE staining also showed wider formation of lymphatic connective tissue on flap-receiver mice, although it was not statistically significant. Immunohistochemistry analysis also showed clearer VEGF-C formation showed by brown coloration in flap-receiver mice p < 0.05 . Expression of CD68 protein was also clearer in flap-receiver mice although the difference was not significant.Conclusion. Addition of tissue flap may help improve lymphatic circulation proven by increased lymphatic circulation and VEGF-C expression."

"[ABSTRAK Kanker payudara merupakan masalah kesehatan yang semakin meningkat di daerah urban. Mastektomi radikal modifikasi (MRM) merupakan upaya pengangkatan kanker payudara yang dapat menimbulkan komplikasi berupa kekakuan bahu, penurunan rentang gerak lengan, dan limfedema. Transverse Rectus Abdominis Modification (TRAM) flap merupakan rekonstruksi payudara menggunakan sebagian besar otot abdomen yang berpotensi menyebabkan penurunan kemampuan otot perut dan hernia. Latihan gerak pada lengan dan abdomen bertujuan meningkatkan rentang gerak sehingga tidak terjadi kekakuan lengan dan abdomen, serta mencegah limfedema dan hernia. Perawat perlu mengedukasi latihan rentang gerak lengan dan abdomen pasca MRM dan TRAM flap agar kualitas hidup semakin meningkat.ABSTRACT Breast cancer is a health problem that the prevalence is increasing in urban areas. Modified radical mastectomy (MRM) is the treatment of breast cancer that can cause complications such as shoulder stiffness, decreased range of motion of the arms, and lymphedema. Modification transverse rectus abdominis (TRAM) flap is a breast reconstruction using abdominal muscles that potentially can cause a decrease in the ability of the abdominal muscle and hernia. The exercise of motion in the arm and abdomen aims to improve the range of motion in order to avoid stiffness of the arms and abdomen, as well as to prevent lymphedema and hernia. Nurses need to promote the range of motion exercises for the arms and abdomen following MRM and TRAM flap to improve the quality of life.;Breast cancer is a health problem that the prevalence is increasing in urban areas. Modified radical mastectomy (MRM) is the treatment of breast cancer that can cause complications such as shoulder stiffness, decreased range of motion of the arms, and lymphedema. Modification transverse rectus abdominis (TRAM) flap is a breast reconstruction using abdominal muscles that potentially can cause a decrease in the ability of the abdominal muscle and hernia. The exercise of motion in the arm and abdomen aims to improve the range of motion in order to avoid stiffness of the arms and abdomen, as well as to prevent lymphedema and hernia. Nurses need to promote the range of motion exercises for the arms and abdomen following MRM and TRAM flap to improve the quality of life., Breast cancer is a health problem that the prevalence is increasing in urban areas. Modified radical mastectomy (MRM) is the treatment of breast cancer that can cause complications such as shoulder stiffness, decreased range of motion of the arms, and lymphedema. Modification transverse rectus abdominis (TRAM) flap is a breast reconstruction using abdominal muscles that potentially can cause a decrease in the ability of the abdominal muscle and hernia. The exercise of motion in the arm and abdomen aims to improve the range of motion in order to avoid stiffness of the arms and abdomen, as well as to prevent lymphedema and hernia. Nurses need to promote the range of motion exercises for the arms and abdomen following MRM and TRAM flap to improve the quality of life.]"