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Muhamad Relly Sofiar
"Latar belakang : Steal Syndrome, adalah salah satu komplikasi pembuatan akses vena untuk hemodialisis, Insidensi steal syndrome yang berat diperkirakan 0,5-5%.11Belum ada pemeriksaan secara baku emas, terdapat berbagai prediktor noninvasif yang dapat menilai derajat steal salah satunya dengan nilai Digital Brachial Indices (DBI). Pada penelitian ini, subjek dengan AVF brachiocephalic dinilai Hand Ischemic Questioner (HIQ) untuk melihat manifestasi yang dikeluhkan berupa rasa dingin nyeri. Berkurangnya sensasi dan kekuatan, serta keram yang dinilai derajat keparahan dan frekuensinya dikorelasikan dengan nilai DBI yang dianggap bermakna sebagai steal syndrome adalah nilai DBI <0,6. Korelasi dari kedua parameter tersebut diharapkan dapat menunjukkan hal yang bermakna dalam praktek dan dalam penanganan pasien-pasien steal syndrome. Subyek dan Metode: Subyek penelitian ini adalah semua pasien yang menjalani hemodialisis dengan akses AVF lengan atas di RSUPN Cipto Mangunkusumo dalam periode bulan Mei-Juni 2019. Pasien akan ditanyakan mengenai berbagai gejala mengenai steal syndrome sesuai dengan HIQ, dan dihitung skor nya, dilanjutkan dengan pengukuran Systolic Digital Pressure menggunakan alat phletysmograph, disisi lengan dengan AVF/AVG dan Systolic Brachial Pressure untuk menentukan DBI pada pasien tersebut. Hasil: Dari data demografik, profil pasien gagal ginjal yang menjalani hemodialisis berdasarkan jenis kelamin laki-laki 37(46,2%) pasien dan perempuan 43(53,8%) dengan rata-rata usia pasien 53 tahun. Skor HIQ nilai minimum adalah 0 dan nilai maksimum adalah 70 dengan nilai median 3. Uji korelasi antara nilai total skor kuesioner HIQ dan nilai DBI didapatkan adanya korelasi dengan nilai p<0.001. uji diagnostik antara Skor HIQ menggunakan nilai cut-off ≥50 dengan nilai DBI <0.6. Dari hasil uji diagnostik antara skor HIQ dan DBI didapatkan nilai sensitivitas 15.3% dan nilai spesifisitas 100%, dengan akurasi diagnostik 58.75%. Kesimpulan: terdapat korelasi yang baik antara skor HIQ dengan DBI pada subyek penelitian ini, menunjukkan HIQ dan DBI ini dapat digunakan sebagai alat diagnostik yang cukup akurat sebagai salah satu metode awal untuk mendeteksi gejala-gejala awal dari Steal Syndrome sebelum dilakukan pemeriksaan tambahan lainnya untuk mengurangi pemeriksaan lanjutan yang tidak perlu.

Background: Steal Syndrome is a complication after a native Arteriovenous Fistule(AVF), there were symtomps of cold sensations, pain, cramps, loss of strength and diminishes of sensibility. A severe steal syndrome incidences was 0.5 - 5%. And there are no gold standard non inavasive examination to predict a steal syndrome, there is Digital Brachial Indices (DBI). In this study all patients on Hemodialysis with brahiocepalic (BC) AVF were questioned and valued for Hand Ischemic Questionaire (HIQ) related symptomps. All those symptomps were valued for its severity and frequencies to correlate with DBI values, DBI <0.6 as a cut-off to consider a steal syndrome. Correlation between those parameter were expected to be significant in evaluate patients suspected steal syndrome in our daily practice. Methods: subjects in this study were all patients on hemodialysis with BC AVF at Cipto Mangunkusumo Hospital within May-June 2019 periods. They were questioned and valued for HIQ (no symptoms of ischemia, 0 points; maximal ischemia, 500 points), and then systolic digital pressure were measured with a phletysmograph, ipsilateral of AVF, continued to measure systolic brachial pressure, and we found DBI values. Results: a demographic profile data, male patients 37(46.2%), female patients 43(53.8%) with mean age 53y.o. Minimum HIQ score was 0 and maximum 70, mean score 3. Correlation between HIQ and DBI was good with p<0.001. Diagnostic test between HIQ and DBI were sensitivity 15.3% and specivity 100% with diagnostic accuracy 58.7%. Conclusions: there were a good correlation between HIQ score and DBI on hemodialysis patients with BC AVF to early detection of steal syndrome symptomps, as diagnostic tools HIQ and DBI shows a good accuracy, to avoid more invasive and expensive examinations."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2019
T58698
UI - Tesis Membership  Universitas Indonesia Library
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Raden Suhartono
"Introduction: Steal syndrome is one of the most feared complications in maintaining arteriovenous fistula (AVF) for hemodialysis. The incidence of steal syndrome in worldwide is estimated to be 0.5-5%. There are various non-invasive examinations to assess the degree of stealing, one of which is the digital brachial index (DBI). In this study, subjects with brachiocephalic AVF were assessed by the hand ischemic questionnaire (HIQ) to assess the manifestations of steal syndrome complained by the patient, which are the sensation of cold, pain, the decrease in sensation and strength, and cramps. The literature about the correlation of DBI with other assessment is still limited. Method: The subjects of this study were all patients undergoing hemodialysis with upper arm AVF at Cipto Mangunkusumo Hospital in the period May – June 2019. Patients will be asked about various symptoms of stealing syndrome, the severity, and also frequency, according to HIQ. The scores were then calculated, followed by scores of DBI measurements using a plethysmograph. The DBI values that considered to be meaningful as stealing syndrome were <0.6. The correlation between the two parameters was then analyzed. Results: From demographic data, characteristics of patients with native AVF by sex were 37 (46.2%) men and 43 (53.8%) women with an average age of 53 years. The minimum value of the HIQ score was 0, and the maximum value was 70, with a median value of 3. The correlation test between the total value of the HIQ questionnaire score and the DBI value found a significant correlation (r = -0.0798, p <0.001). A diagnostic tests was performed between HIQ scores using a cut-off value ≥50 with a DBI value <0.6 as a reference. It was obtained a sensitivity value of 15.3% and a specificity value of 100%, with a diagnostic accuracy of 58.75%. Conclusion: There was a good correlation between HIQ and DBI in patients undergoing hemodialysis using upper arm native AVF. The use of HIQ as a screening tool in native upper arm AVF patients is less recommended, but its use for patients who are suggestive of stealing syndrome has good specificity results."
Jakarta: PESBEVI, 2020
616 JINASVS 1:1 (2020)
Artikel Jurnal  Universitas Indonesia Library
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Billy Stephanus Karundeng
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Latar Belakang: Steal syndrome yang terjadi karena akses vaskular adalah komplikasi yang paling ditakutkan setelah pembuatan suatu fistula arteriovena, untuk itu perlu dikembangkan suatu bentuk pemeriksaan untuk deteksi awal. Hand ischemia questionnaire dan pengukuran peak systolic velocity arteri radialis dan arteri ulnaris merupakan bentuk pemeriksaan subyektif dan obyektif yang dipakai untuk mendeteksi steal syndrome

Tujuan: Untuk mengetahui korelasi antara hand ischemia questionnaire dengan peak systolic velocity pada arteri radialis dan arteri ulnaris pada pasien hemodialisa dengan akses fistula native lengan atas untuk mendeteksi gejala steal syndrome.

Metode: Desain yang digunakan adalah desain potong lintang. Penelitian ini dilakukan di RSUPN Dr. Cipto Mangunkusumo selama periode Maret hingga Mei 2019 pada pasien yang menjalani hemodialisis dengan menggunakan akses native fistula lengan atas dengan atau tanpa gejala iskemia pada tangan, metode pengisian kuesioner dengan cara wawancara termpimpin, kemudian dilanjutkan dengan pengukuran peak systolic velocity arteri radialis dan arteri ulnaris distal dari fistula arteriovena.

Hasil: Total sampel 80, sampel terbanyak berjenis kelamin wanita 43 (53,8%) sedangkan pria sebanyak 37 orang (46,2%). Sebanyak 91,2% sampel dengan FAV BC Sinistra, dengan median usia 53 tahun. Total skor HIQ yang didapat, minimum 0, maksimum 70, dengan nilai median 3. Nilai PSV arteri radialis minimum 20 cm/detik, maximum 79 cm/detik, median 40 cm/detik. Nilai PSV arteri ulnaris minimum 16 cm/detik, maksimum 70 cm/detik, median 41 cm/detik. Terdapat korelasi yang bermakna (p<0,001) antara hand ischemia questionnaire dengan peak systolic velocity arteri radialis dan arteri ulnaris pada pasien dengan native fistula lengan atas, namun setelah dilakukan uji diagnostik didapatkan sensitivitas hanya sebesar 15% dan spesifisitas 100%

Simpulan: Terdapat korelasi yang signifikan antara hand ischemia questionnaire dengan nilai peak systolic velocity arteri radialis dan arteri ulnaris pada pasien dengan native fistula lengan atas, namun karena didapatkan sensitifitas yang rendah sehingga hand ischemia questionnaire tidak dapat digunakan sebagai pemeriksaan awal untuk mendeteksi steal syndrome pada pasien dengan tanpa gejala iskemia tangan sebelumnya.


Background: Dialysis access steal syndrome is the most feared complication after making arteriovenous fistulas, for which a form of examination for early detection needs to be developed. Hand ischemia questionnaire and measurement of peak systolic velocity of the radial artery and ulnar artery distal of the arteriovenous fistula are forms of subjective and objective examination used to detect steal syndrome

Objective: To determine the correlation between hand ischemia questionnaire with peak systolic velocity in the radial artery and ulnar artery in hemodialysis patients using native upper arm arteriovenous fistula to detect symptoms of steal syndrome.

Method: The design used is a cross-sectional design. This research was conducted at RSUPN Dr. Cipto Mangunkusumo during the period March to May 2019 in patients undergoing hemodialysis using native upper arm arteriovenous fistula access with or without symptoms of ischemia in the hand, the method of filling in the questionnaire by guided interview, then followed by measurements of the radial and ulnar artery peak stystolic velocity distal to the arteriovenous fistula

Results: The total sample was 80, the most samples were female 43 (53.8%) while men were 37 (46.2%). 91.2% of the samples had av fistula BC Sinistra, with a median age of 53 years. The total HIQ score obtained is  with a minimum value of 0, a maximum of 70, with a median value of 3. The radial arterial PSV value is with a minimum value of 20 cm/second, a maximum of 79 cm/second, a median of 40 cm/second. The ulnar arterial PSV value is at least 16 cm/second, maximum 70 cm/second, median 41 cm/second. There was a significant correlation (p <0.001) between the hand ischemia questionnaire and the peak systolic velocity of the radial and ulnar artery in patients with native upper arm arteriovenous fistula, but after a diagnostic test the sensitivity was only 15% with 100% specificity.

Conclusion: There was a significant correlation between the hand ischemia questionnaire and the value of the peak systolic velocity of the radial and ulnar arteries in patients with native upper arm fistula, but because of the low sensitivity that the hand ischemia questionnaire could not be used as an initial examination to detect steal syndrome in patients without previous symptoms of hand ischemia.

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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2019
T58697
UI - Tesis Membership  Universitas Indonesia Library
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Billy Stephanus Karundeng
"Introduction: Steal syndrome that occurs due to vascular access is one of the most feared complications after making a fistula arteriovenous (FAV). It is necessary to develop an assessment for early detection. Hand ischemia questionnaire (HIQ) and measurement of peak systolic velocity (PSV) of the radial artery and the ulnar artery are a form of subjective and objective examinations used to detect steal syndrome. The aim is to determine the correlation between HIQ and PSV of the radial artery and ulnar artery in hemodialysis patients with upper arm’s native FAV to detect symptoms of steal syndrome. Method: This is a cross-sectional study conducted in Cipto Mangunkusumo National Hospital from March to May 2019. Patients undergoing hemodialysis using upper arm native access FAV with or without symptoms of ischemia in the hands were included. Patients were asked to fill HIQ by interview, and then continued with measurement of PSV of the radial arteries and distal ulnar arteries from the hands with FAV. Results: A total of 80 samples were taken with 43 were women (53.8%), and 37 were men (46.2%). About 91.2% of the samples were FAV at the brachiocephalic level. The median age of the samples was 53 years. From the total HIQ score obtained, the results were a minimum of 0, maximum of 70, and a median value of 3. PSV of radial artery were minimum of 20 cm/s, maximum of 79 cm/s, and median 40 cm/s. The minimum PSV of the ulnar artery was 16 cm/s, the maximum was 70 cm/s, and the median was 41 cm/s. There was a significant correlation between the hand ischemia questionnaire and the peak systolic velocity of the radial artery and the ulnar artery in patients with native upper arm FAV (p <0.001), but after diagnostic testing, it was found that sensitivity was only 15% and specificity was 100%. Conclusion: There was a significant correlation between hand ischemia questionnaire and peak systolic velocity of the radial artery and ulnar artery in patients with upper arm native FAV, but due to the low sensitivity, the hand ischemia questionnaire cannot be used as an initial examination to detect steal syndrome in patients with no symptoms of hand ischemia."
Jakarta: PESBEVI, 2020
616 JINASVS 1:1 (2020)
Artikel Jurnal  Universitas Indonesia Library
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Muhammad Ade Junaidi
"Status indeks masa tubuh pada pasien penyakit ginjal kronik yang menjalani hemodialisis menjadi suatu penentuan tingkat morbiditas dan mortalitas. Pada pasien penyakit ginjal kronik yang menjalani hemodialisis dapat mengalami penurunan atau peningkatan indeks masa tubuh. Kami menggunakan metode potong lintang pada studi ini. Penelitian dilakukan pada 108 pasien hemodialisis di bangsal hemodialisis Subbagian Ginjal Hipertensi Departemen Ilmu Penyakit Dalam RSCM pada bulan Februari 2009. Kemudian diambil data dari status pasien mengenai berat badan kering dan tinggi badan pasien saat pertama kali menjalani hemodialisis dan bulan februari 2009. Berdasarkan perubahan indeks massa tubuh maka data ini dibagi atas 2 kelompok yaitu kelompok dengan peningkatan indeks masa tubuh dan penurunan indeks masa tubuh. Pasien berumur rerata 50,4 ± 13,4 tahun, terdiri dari 57% pria dan 43% wanita, dan lama menjalani hemodialisis rerata 2.3 tahun (0.3-17.5). Dengan uji Pearson didapatkan korelasi positif yang bermakna antara lama menjalani hemodialisis dengan peningkatan indeks masa tubuh (p<0.001, r = 0.727) maupun penurunan indeks masa tubuh (p<0.001, r = 0.709). Disimpulkan bahwa lama menjalani hemodialisis mempengaruhi peningkatan maupun penurunan indeks massa tubuh pasien hemodialisis.

Status of body mass index on chronic kidney disease patients who undergo hemodialysis is a determinant factor for morbidity and mortality. Hemodialysis patients can increase or decrease their body mass indexes. In this study, we used cross sectional method. We selected 108 patients that has already undergone hemodialysis twice a week for at least three months in hemodialysis ward of Cipto Mangunkusumo Hospital in February 2009. Data are taken from dry weight and body height in medical records at the initial hemodialysis and on February 2009. We categorized patients into increased body mass index category and decreased body mass index category. The patients have mean age of 50,4 ± 13,4 years and a mean duration of hemodialysis of 2.3 (0.3-17.5) years, 57% were male and 43% were female. By Pearson analysis, there was significant positive correlation between increased body mass index (p<0.001, r = 0.727) and decreased body mass index (p<0.001, r = 0.709) with hemodialysis duration. It was concluded that duration of hemodialysis significantly influenced body mass index in hemodialysis patients."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2009
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UI - Skripsi Open  Universitas Indonesia Library
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Lisa Safitri
"Latar Belakang: Prevalensi penyakit arteri perifer PAP pada pasien dengan penyakit ginjal kronik PGK terlihat meningkat sejak stadium 3. Alat diagnostik nilai indeks ankle brachial ABI cukup akurat dalam mendeteksi PAP pada populasi normal. Pada PGK yang sering terjadi kalsifikasi pembuluh darah dimana nilai ABI dapat menjadi normal atau tinggi meski sudah ada stenosis pembuluh darah. Kalsifikasi pada ibu jari jarang terjadi membuat pemeriksaan nilai indeks toe brachial TBI mempunyai kelebihan dalam menilai PAP pada PGK.
Tujuan: Untuk mendapatkan proporsi PAP berdasarkan nilai ABI dan TBI serta informasi mengenai profil PAP pada PGK predialisis dan faktor yang diduga berhubungan.
Metode: Penelitian potong lintang pada pasien PGK di poliklinik Ilmu Penyakit Dalam, poliklinik Ginjal Hipertensi, poliklinik Kardiologi dan poliklinik Kardiologi Pusat Jantung Terpadu RSCM periode Oktober 2015-Maret 2016. Data didapatkan dari hasil wawancara, pemeriksaan fisik, nilai ABI dan TBI, serta pemeriksaan laboratorium. Studi deskriptif dilakukan dengan melihat proporsi PAP berdasarkan nilai ABI dan TBI, proporsi variabel dan penentuan nilai rerata dan median.
Hasil: Terdapat 75 pasien yang memenuhi kriteria penelitian. Proporsi PAP berdasarkan nilai ABI dan TBI 60 IK 95 49 -; 71. Nilai ABI. 0,9 dan TBI. 0,7 digunakan sebagai cut off dalam diagnosis PAP. Proporsi PAP pada tiap stadium ginjal mulai terlihat besar. Pasien dengan PAP lebih banyak laki-laki 51,1 dan rerata IMT 23,57 3,5 kg/m2. Median usia pasien 64 tahun 33-74 tahun. Nilai median ABI 1,04 0,7-1,26 dan TBI 0,61 0,31-0,74. Sebagian besar tidak merokok 53,3, mempunyai komorbiditas hipertensi 84, diabetes melitus 64, penyakit jantung koroner 57 dan dislipidemia 40. Nilai median laju filtrasi glomerulus 31,6 6,3-57,6, nilai median albuminuria 153 mg/g kreatinin 7,9-10767,3, nilai median kalsium. mg/dL 7,2-9,8 mg/dL, nilai median fosfat 3,9 mg/dL 1,9-5,7 mg/dL, rerata nilai produk CaxPO4 33,7 6,5 mg2/dL2 dan nilai median hsCRP 1,3 mg/L 0,1-19,19 mg/L. Proporsi pasien dengan hipertensi lebih besar pada pasien dengan PAP. Sementara proporsi DM tidak terkontrol lebih besar dibandingkan yang terkontrol 44. 20.
Simpulan: Proporsi PAP pada pasien PGK predialisis berdasarkan nilai ABI dan TBI sebesar 60. PAP pada PGK predialisis lebih banyak pada subjek dengan komorbiditas, diabetes melitus yang tidak terkontrol, stadium. klasifikasi Fontaine dan kecenderungan albuminuria yang meningkat.

Background The prevalence of peripheral artery disease PAD in chronic kidney disease patients is increasing in CKD stage. or higher. Ankle brachial index is an accurate diagnostic tool in population without CKD. Higher prevalence of arterial calcification in CKD can lead to. normal or high ABI in stenotic vessel. Toe vessels are less susceptible to calcification, therefore toe brachial index TBI measurement can be more useful for PAD assessment in CKD population.
Objectives: The aim of the study is to determine the profile of PAD based on ankle brachial index and toe brachial index in predialysis CKD patients.
Methods: cross sectional study was conducted in outpatient clinics of Dr. Cipto Mangunkusumo hospital from October 2015 to March 2016. The data were obtained by interview, ABI and TBI measurement, and analyzing the laboratories values.
Results: In 75 patients ABI and TBI measurement were conducted simultaneously. ABI 0.9 and or TBI 0.7 had been used as cut off values for diagnosing PAD. PAD proportion based on ABI and TBI in CKD predialysis is 60 IK 95 49 - 71. PAD proportion in every CKD stage are high. Most of the subject are male 51.1 and the mean body mass index value is 23.57 3.5 kg m2. The age median is 64 year old 33 74 year old. The median value of ABI is 1.04 0.7 1.26 and TBI 0.61 0.31 0.74. Most of the patients are non smoker 53.3, had hypertension 84, diabetic 64, coronary artery disease 57 and dyslipidemia 40. Median value of glomerulus filtration rate is 31.6 ml menit 1.73 m2 6.3 57.6 ml menit 1.73 m2, median value of albuminuria 153 mg. kreatinin 7.9 10767.3 median value of calcium. mg dL 7.2 9.8 mg dL, median value of phosphate 3.9 mg dL 1.9 5.7 mg dL, mean value of CaxPO4 product is 33.7 6.5 mg2 dL2 and median value of hsCRP 1.3 mg. 0.1 19.19 mg.. Most patient with PAD had. greater proportion of hypertension. The proportion of uncontrolled diabetes are higher in patient with PAD 44 vs 20.
Conclusion PAD proportion based on ABI and TBI is 60 IK 95 49 - 71. Most of the patients with PAD in CKD predialyis are with uncontrolled diabetes, stage II of Fontaine classification, increased albuminuria.
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2016
T55632
UI - Tesis Membership  Universitas Indonesia Library
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Taufan Hidayat
"Latar belakang: Penyebab utama morbiditas dan mortalitas serta biaya tinggi dari penyakit ginjal kronis adalah disfungsi akses vaskular untuk hemodialisis, yaitu stenosis fistula arteri-vena (AVF). Oksida nitrit (NO) memiliki peran penting menghambat stenosis dan berperan dalam maturasi fistula. Paparan sinar matahari yang mengandung sinar ultraviolet A (UVA) diketahui dapat meningkatkan kadar NO plasma, sehingga diharapkan dapat menurunkan angka stenosis AVF. Tujuan penelitian: Menilai efek pajanan UVA terhadap NO plasma dan stenosis AVF. Metode: Penelitian eksperimental dengan randomisasi ini dilakukan di RSUP Persahabatan pada bulan Februari hingga Maret 2022. Pasien PGK stadium 5 yang menjalani hemodialisis melalui akses AVF radiosefalika yang sudah matur yang memenuhi kriteria inklusi dan eksklusi dibagi menjadi kelompok kontrol dan perlakuan. Kelompok kontrol diberikan sinar tanpa radiasi dan kelompok perlakuan diberikan sinar UVA (9J/cm2) pada area fistula setiap kali hemodialisis (12 kali) dalam 6 minggu. Kadar NO dan derajat stenosis fistula sebelum dan sesudah penyinaran dicatat dan dianalisa menggunakan SPSS 20.0. Hasil: Terdapat 41 subjek yang memenuhi kriteria inklusi dan eksklusi, dengan 4 subjek drop-out akibat COVID-19. Total subjek yang dianalisis adalah 37 dengan 18 pada kelompok kontrol dan 19 pada kelompok perlakuan. Tidak ditemukan perbedaan yang signifikan antara kelompok kontrol dan perlakuan dalam peningkatan kadar NO maupun derajat stenosis AVF, dengan selisih kadar NO awal dan akhir pada kelompok kontrol dan perlakuan sebesar 6,7±55,5 dan 3,4±39,2 µmol/L, serta selisih derajat NO awal dan akhir pada kelompok kontrol dan perlakuan sebesar 0,6(-6,7 – 51,2)% dan 0,4(-16,0 – 18,1)%. Kesimpulan: Penelitian ini belum dapat membuktikan adanya pengaruh penyinaran UVA terhadap peningkatan kadar NO plasma ataupun penurunan derajat stenosis AVF. Hal ini dapat disebabkan dosis sinar UVA yang rendah, durasi penelitian yang singkat dan jumlah sampel yang sedikit. Perlu dilakukan studi lanjutan dengan dosis sinar UVA bertingkat, durasi penelitian lebih lama dan jumlah sampel yang lebih banyak.

Background: Arteriovenous fistula (AVF) stenosis is a vascular access dysfunction in hemodialysis (HD) which is the main cause of the high morbidity, mortality, and cost on chronic kidney disease (CKD). Nitric oxide (NO) has an essential role in preventing AVF stenosis and fistula maturation. Ultraviolet-A (UVA) exposure from the sun is known to increase plasma NO levels, and hopefully can decrease the incidence of AVF stenosis. Purpose: To analyze the effect of UVA exposure towards NO and AVF stenosis. Patients and methods: This randomized controlled study was conducted in RSUP Persahabatan from February to March 2022. Patients with grade 5 CKD who underwent hemodialysis via mature radio cephalic AVF that meet the inclusion and exclusion criteria were randomized into control and study groups. Control groups were given regular blue light, while study groups were given UVA light (9J/cm2) at the area of AVF twelve times in six weeks. Plasma NO levels and AVF stenosis degree before and after light exposure was recorded and analyzed using SPSS 20.0. Results: A total of 41 subjects meet the inclusion and exclusion criteria. There were 4 drop-outs due to COVID-19, with 37 remaining subjects; 18 in the control and 19 in the study group. There were no significant difference between the control and treatment groups in increasing NO levels or the degree of AVF stenosis. The difference of NO levels and degree of stenosis between pre- and post-intervention in the control and intervention group was 6,7±55,5 and 3,4±39,2 µmol/L, and 0,6(-6,7 – 51,2)% and 0,4(-16,0 – 18,1)% respectively. Conclusion: This study could not prove the effect of UVA irradiation on increasing plasma NO levels or decreasing the degree of AVF stenosis. Further studies with stratified doses of UVA irradiation, longer duration and larger sample sizes should be done in continuation to this study."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2022
T-pdf
UI - Tesis Membership  Universitas Indonesia Library
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Syifa Fauziatun Nikmah
"Gagal ginjal kronik merupakan penyakit terminal yang progresif dan ireversibel. Fungsi ginjal meliputi regulasi cairan, detoksifikasi serta produksi hormon. Pasien dengan GGK harus menjalani hemodialisis rutin sebagai terapi penggantian ginjal sementara. Pasien yang sedang menjalani hemodialisis seringkali mengalami masalah overload cairan, dimana harus melakukan pembatasan cairan untuk menghindari kelebihan cairan. Masalah overload cairan dapat menimbulkan masalah kesehatan lainnya bahkan dapat berujung dengan kematian. Oleh karena itu, dibutuhkan program pembatasan cairan yang efektif dan efisien melalui upaya pemantauan intake output cairan untuk mencegah komplikasi. Penulisan karya ilmiah ini menggunakan metode studi kasus dengan tujuan menggambarkan metode pemantauan intake output cairan pasien GGK dengan menggunakan fluid intake output chart. Pemantauan tersebut terbukti efektif untuk menangani overload cairan pada klien, dibuktikan dengan berkurangnya manifestasi overload cairan pada klien.

Chronic Kidney Disease is a progressive and irreversible terminal disease. Kidney function includes fluid management, detoxification and hormone production. Patients with Chronic Kidney Disease should replace hemodialysis as a temporary kidney replacement therapy. Patients who are trying to solve the problem of excess fluid, which must do fluids to avoid excess fluid. The problem of excess fluid can cause health problems. Therefore, an effective and efficient fluid program is needed to overcome the problem, which is issued through an fluid intake output monitoring. This scientific study was a case study method with the aim of evaluating the intake method for patients with CKD by using a fluid intake output chart. This monitoring has proven to be effective in dealing with excess fluid in the client, evidenced by the reduction in manifestations of excess fluid in the client."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2020
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UI - Tugas Akhir  Universitas Indonesia Library
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Basith Halim
"Menurut World Health Organization (WHO) ada sekitar 46,6 juta penderita stroke yang mengalami disabilitas. Selama ini dalam menentukan program rehabilitasi medik yang tepat dengan memperhatikan dominansi tangan pasien pasca stroke masih belum dilakukan, sehingga penentuan dominansi tangan ini penting untuk dilakukan. Berbagai studi meneliti mengenai hubungan lateralisasi otak dan dominansi tangan namun masih jarang yang meneliti hubungan sisi hemiparesis pada pasien stroke dengan dominansi tangan dan menghubungkannya dengan pemulihan fungsi anggota gerak atas. Penelitian ini bertujuan untuk menjawab pertanyaan tersebut dengan mengetahui variasi perubahan dominansi tangan pasca stroke yang diukur dengan Edinburgh Handedness Inventory - Short Form (EHI-SF) dan fungsi anggota gerak atas pasca stroke yang diukur dengan Fugl-Meyer Upper Extremity (FMA-UE) dan Chedoke Arm and Hand Activity Inventory (CAHAI). Penelitian observasional prospektif dengan desain cross sectional ini dilakukan di Poli Rehabilitasi Medik Neuromuskular RSCM pada bulan September 2021 sampai Oktober 2022. Populasi subjek adalah pasien stroke iskemik fase subakut dan kronik dengan hemiparesis yang memenuhi kriteria penerimaan dan penolakan. Dominansi tangan ditentukan dengan EHI-SF, sedangkan fungsi anggota gerak pasca stroke diukur dengan FMA-UE dan CAHAI. Penelitian ini melibatkan 62 orang subjek yang terbagi menjadi dua kelompok, yaitu kelompok dominan ipsilateral (n=27) dan dominan kontralateral (n=35). Didapatkan hubungan bermakna antara sisi hemiparesis dengan dominansi tangan (p < 0,001). Selain itu, didapatkan hubungan bermakna antara pemulihan fungsi anggota gerak dengan dominansi tangan pasca stroke. Tidak didapatkan hubungan yang bermakna antara pemulihan fungsi anggota gerak dengan sisi hemiparesis. Kesimpulan penelitian ini adalah dominansi tangan berhubungan dengan sisi hemiparesis dan pemulihan fungsi anggota gerak, dan pemulihan fungsi anggota gerak tidak berhubungan dengan sisi hemiparesis.

According to the World Health Organization (WHO) there are around 46.6 million stroke sufferers who experience disability. So far, determining the right medical rehabilitation program based on hand dominance in post-stroke patients has not been carried out. Various studies have examined the relationship between brain lateralization and hand dominance, but the relationship between the side of hemiparesis in stroke patients with hand dominance and their correlation with the recovery of upper limb function has not been established. This study aims to answer this question by knowing the variations in post-stroke hand dominance as measured by the Edinburgh Handedness Inventory - Short Form (EHI-SF) and post-stroke upper limb function as measured by Fugl-Meyer Upper Extremity (FMA-UE) and Chedoke Arm and Hand Activity Inventory (CAHAI). This prospective observational study with cross-sectional design was conducted at the Neuromuscular Medical Rehabilitation Polyclinic, Cipto Mangunkusumo Hospital from September 2021 to October 2022. The study population was subacute and chronic ischemic stroke patients with hemiparesis who met the inclusion and exclusion criteria. Hand dominance was determined by EHI-SF, while post-stroke limb function was measured by FMA-UE and CAHAI. This study involved 62 subjects who were divided into two groups, namely the dominant ipsilateral group (n=27) and the dominant contralateral group (n=35). A significant relationship was found between the side of the hemiparesis and hand dominance (p <0.001). In addition, a significant relationship was found between the recovery of limb function and hand dominance after stroke. No significant relationship was found between the recovery of limb function and the side of the hemiparesis. The conclusion of this study is hand dominance is associated with the side of the hemiparesis and recovery of limb function, and recovery of limb function is not associated to the side of hemiparesis.
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
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UI - Tugas Akhir  Universitas Indonesia Library
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