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""Biomedical Informatics: Computer Applications in Health Care and Biomedicine meets the growing demand of practitioners, researchers, educators, and students for a comprehensive introduction to key topics in the field and the underlying scientific issues that sit at the intersection of biomedical science, patient care, public health, and information technology (IT). This 4th edition reflects the remarkable changes in both computing and health care that continue to occur and the exploding interest in the role that IT must play in care coordination and the melding of genomics with innovations in clinical practice and treatment. New chapters have been introduced on the health information infrastructure, consumer health informatics, telemedicine, translational bioinformatics, clinical research informatics, and health IT policy, while the others have all undergone extensive revisions, in many cases with new authors. The organization and philosophy are unchanged, focusing on the science of information and knowledge management and the role of computers and communications in modern biomedical research, health, and health care. Emphasizing the conceptual basis of the field rather than technical details, it provides an introduction and extensive bibliography so that readers can comprehend, assess, and utilize biomedical informatics and health IT. The volume focuses on easy-to-understand examples, a guide to additional literature, chapter summaries, and a comprehensive glossary with concise definitions of recurring terms for self-study or classroom use."--Back cover."

"This book describes the core resources in informatics necessary to support biomedical research programs and how these can best be integrated with hospital systems to receive clinical information that is necessary to conduct translational research. The first section of the book discusses important technical challenges underlying computer-based pediatric research, while subsequent sections discuss informatics applications that support biobanking and a broad range of research programs. Pediatric Biomedical Informatics provides practical insights into the design, implementation, and utilization of informatics infrastructures to optimize care and research to benefit children. "

"The growth in the bioinformatics and computational biology fields over the last few years has been remarkable. The analysis of the datasets of next generation sequencing needs new algorithms and approaches from fields such as databases, statistics, Data mining, machine learning, optimization, computer science and artificial intelligence. Also systems biology has also been emerging as an alternative to the reductionist view that dominated biological research in the last decades. This book presents the results of the 6th International Conference on Practical Applications of Computational Biology & Bioinformatics held at University of Salamanca, Spain, 28-30th March, 2012 which brought together interdisciplinary scientists that have a strong background in the biological and computational sciences."

"Salah satu metode deteksi dini kanker mulut rahim melalui deteksikeberadaan atau infeksi HPVadalah metode Hybrid Capture. Dalampenelitian ini akan dicari primer sebagai pengganti probe dalam rangkamemodifikasi metode Hybrid Capture. Metode yang digunakan adalahmetode bioinformatik. Sekuens genom HPV dari database dibagi menjaditiga kelompok beidasarkan kecenderungannya menyebabkan kanker, dandata dibuat dalam tiga bentuk yaitu genom total, gen E?, dan gen E7.Multiple alignment dilakukan untuk menoari kesamaan antar sekuenstersebut, dan memperoleh conserved area yang akan digunakan sebagaitemplate. Untuk mendapatkan daerah yang spesifik, maka seleksi lebih lanjutterhadap conserved region menggunakan Basic Local Alignment SearchTool (BLAST). Diperoleh empat segmen dengan basil terbaik, yaitu segmen3 dan 27 dari basil alignment genom total High-Risk. segmen 1 dari basilalignment daerah gen E7 High-Risk, dan segmen 4 dari basil alignmentdaerah gen E7 High-Risk + Low Risk. "