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"ABSTRAKNeonatal jaundice sering terjadi pada minggu pertama awal kehidupan bayi setelah lahir. Deteksi dini neonatal jaundice dapat mencegah terjadinya kernikterus sebagai komplikasi tingginya kadar bilirubin pada neonatus. Visual assessment merupakan salah satu pemeriksaan untuk menilai neonatal jaundice yang diperkenalkan oleh Kramer. Tujuan penelitian ini adalah mengetahui nilai sensitivitas, spesifitas dan akurasi visual assessment atau pemeriksaan Kramer pada neonatal jaundice. Penelitian ini menggunakan desain cross sectional pada 102 bayi dengan teknik pengambilan sampel consecutive sampling. Analisis data dilakukan dengan tabel uji diagnostik 2x2. Hasil penelitian ini menunjukkan bahwa visual assessment pada neonatal jaundice nilai sensitivitas 76,92 , spesifisitas 89,47 , dan nilai akurasi 86,27 . Penelitian ini dapat menjadi informasi untuk pengembangan pemeriksaan noninvasif lainnya dalam menilai neonatal jaundice untuk menurunkan angka mobiditas neonatus. Kata Kunci: akurasi, neonatal jaundice, sensitivitas, spesitifitas, visual assessment

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ABSTRACTNeonatal jaundice often occurs in the first week after birth. Early detection of neonatal jaundice can prevent kernicterus as a complication of high levels of bilirubin in neonates. Visual assessment is one of the examinations to assess the neonatal jaundice introduced by Kramer. The purpose of this study was to determine the sensitivity, specificity and accuracy of visual assessment or Kramer examination in neonatal jaundice. This study used cross sectional design to examine 102 babies as the sample which was selected by convenience sampling method. 2x2 table diagnostic test was employed in this study to analyze the data. The results of this study showed that visual assessment in neonatal jaundice had sensitivity valued 76.92 , specificity valued 89.47 , and accuracy valued 86.27 . This research can be acknowledged for the development of other non invasive examinations in assessing neonatal jaundice for decreasing the number of neonatal morbidity. Keywords accuracy, neonatal jaundice, sensitivity, specificity, visual assessment "

"Ikterus neonatorum merupakan kondisi pada neonatus karena peningkatan bilirubin dalam darah. Ikterus neonatus mempunyai tanda diantaranya kulit dan sklera yang kuning akibat bilirubin tak terkonjugasi. Salah satu terapi hyperbilirubinemia adalah fototerapi. Tujuan penelitian adalah untuk mengetahui hubungan durasi fototerapi dengan nilai bilirubin total akhir pada pasien ikterik neonatorum di RS Polri DKI Jakarta. Penelitian ini menggunakan desain cross sectional dengan total 103 data yang mengalami ikterus neonatorum sebagai responden. Hasil penelitian menunjukkan rata-rata kadar bilirubin awal 14, 81 mg/dL, kadar bilirubin setelah fototerapi selama 24 jam menghasilkan penurunan sebesar 2,60 mg/dL dan fototerapi selama 48 jam menghasilkan rata-rata penurunan bilirubin sebesar 3,69 mg/dL. Terdapat hubungan durasi fototerapi dengan nilai bilirubin total pada 24 jam dan 48 jam pasca fototerapi (p Value <0,005). Rekomendasi penelitian ini adalah perlu dilakukannya eksplorasi factor-faktor yang berhubungan dengan efektivitas fototerapi.

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Neonatal jaundice is a condition in neonates due to increased bilirubin in the blood. Neonatal jaundice has signs including yellow skin and sclera due to unconjugated bilirubin. One of the therapies for hyperbilirubinemia is phototherapy. The purpose of the study was to determine the relationship between the duration of phototherapy and the final total bilirubin value in neonatal jaundice patients at DKI Jakarta Police Hospital. This study used a cross sectional design with a total of 103 data who experienced neonatal jaundice as respondents. The results showed an average initial bilirubin level of 14, 81 mg/dL, bilirubin levels after phototherapy for 24 hours resulted in a decrease of 2.60 mg/dL and phototherapy for 48 hours resulted in an average decrease in bilirubin of 3.69 mg/dL. There is a relationship between the duration of phototherapies with total bilirubin values at 24 hours and 48 hours after phototherapy (p value <0.005). The recommendation of this study is the need to explore the factors associated with the effectiveness of phototherapy."

"ABSTRAKFragmen bilirubin yang tidak terkonjugasi dan tidak terikat albumin (bilirubinbebas) pada neonatus dapat menembus sawar darah otak sehingga terjadikerusakan otak berupa ensefalopati bilirubin akut. Salah satu gejala ensefalopatibilirubin akut adalah tuli sensorineural. Penelitian sebelumnya menunjukkanbahwa bilirubin bebas mempunyai neurotoksisitas lebih besar dibandingkandengan bilirubin total, namun pemeriksaan bilirubin bebas lebih sulit, rumit,mahal dan belum tersedia di klinik; sehingga perlu dicari pemeriksaan lain yanglebih praktis dan aplikatif. Salah satu pilihan untuk menentukan neurotoksisitasbilirubin adalah pengukuran rasio bilirubin total terhadap albumin (BT/A).Penelitian ini merupakan penelitian potong lintang berulang, bersifatobservasional, longitudinal, dan prospektif berupa uji diagnostik untukmengetahui proporsi tuli sensorineural yang diprediksi berdasarkan nilai rasioBT/A tertentu pada neonatus BBLR dengan hiperbilirubinemia. Penelitian inidilakukan dalam periode bulan Agustus 2015 sampai dengan Maret 2016, dengandua tahap pemeriksaan OAE dan BERA. Pemeriksaan pertama sebagai skriningpendengaran dilakukan saat subjek berumur ≥ 7β jam?1 minggu dan pemeriksaankedua/diagnostik pada usia 3?6 bulan.Dari 131 subjek yang dilakukan skrining pendengaran dengan OAE dan BERA,terdapat 70 subjek dengan hasil refer dan 61 dengan hasil pass. Lima puluh satusubjek datang pada pemeriksaan kedua/diagnostik (response rate 38,9%). Hasilpemeriksaan diagnostik adalah 9 subjek tuli sensorineural (6,87%) yang terdiridari 5 subjek tuli sensorineural bilateral, 2 subjek tuli sensorineural unilateral dan2 subjek neuropati auditorik. Rasio BT/A berperan terhadap terjadinya tulisensorineural dengan OR 16, p = 0,003, sensitivitas 89% dan spesifisitas 67%.Pada penelitian ini juga didapatkan angka rujukan bilirubin total dan rasio BT/Ayang dapat menyebabkan tuli sensorineural pada neonatus BBLRhiperbilirubinemia yaitu 12,21 mg/dL dan 0,46.Rasio BT/A dapat digunakan sebagai prediktor tuli sensorineural pada neonatusBBLR dengan hiperbilirubinemia.

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ABSTRACTIn neonates, unconjugated unbound bilirubin (free bilirubin) can penetrate theblood brain barrier, causing brain damage in the form of acute bilirubinencephalopathy as one of the symptoms is sensorineural hearing loss. Previousresearch has demonstrated that free bilirubin neurotoxicity was more sensitivethan total bilirubin, but the free bilirubin test is more difficult, complicated,expensive and not available in the clinic; thus it is necessary to find other testswhich is more practical and applicable. One of the option to determine thebilirubin neurotoxicity is a measurement of the ratio of total bilirubin to albumin(BT/A).This is a repeated cross sectional study done in observational, longitudinal andprospective diagnostic tests to determine the proportion of sensorineural hearingloss predicted based on the value BT/A ratio in low birth weight (LBW) neonateswith hyperbilirubinemia. The study was conducted from August 2015 until March2016, with two-stage examination of the OAE and BERA, i.e. ≥ 7β hours?1 weekand age of 3?6 months respectively.One hundred and thirty one subjects underwent hearing screening, and it revealedthat 70 subjects diagnosed as refer and the rest (61 subjects) was pass. During thesecond examination/diagnostics with response rate at 38.9%, 9 from 51 subjectswere diagnosed as sensorineural hearing loss (6.87%), i.e. five subjects withbilateral sensorineural hearing loss, two subjects with unilateral sensorineuralhearing loss and two subjects with auditory neuropathy. The BT/A ratiocontributes to the occurrence of sensorineural hearing loss with OR 16, p = 0.003,sensitivity 89% and specificity 67%. It also revealed in this study that thereference figure of bilirubin total and BT/A ratio were 12.21 mg/dL and 0.46respectively. Those reference value can be used to predict sensorineural hearingloss in LBW neonatal with hyperbilirubinemia.Ratio of BT/A can be used as a predictor of sensorineural hearing loss in LBWneonates with hyperbilirubinemia."

"Telah dilakukan penelitian untuk mengetahui bahwa ekstrak etanol rimpang temu mangga Curcuma mangga Val. berpengaruh terhadap kadar bilirubin total dan bilirubin direct akibat kerusakan hati yang diinduksi oleh karbon tetraklorida CCl4 . Hewan uji yang digunakan dalam penelitian yaitu 24 ekor tikus Rattus norvegicus L. jantan galur Sprague-Dawley yang dibagi menjadi enam perlakuan KK1, KK2, KP1, KP2, KP3, dan KP4 dengan empat kali ulangan. Kelompok KK1 merupakan kelompok kontrol normal yang tidak diinjeksikan CCl4 dan dicekok CMC 0.5 , KK2 merupakan kelompok kontrol perlakuan yang diinjeksikan CCl4 sebanyak 1 ml/kgBB secara intraperitoneal dan dicekok CMC 0,5 . Kelompok KP1, KP2, KP3, dan KP4 merupakan kelompok perlakuan yang diinjeksikan CCl4 1 ml/kgBB dan diberikan ekstrak temu mangga dengan dosis berturut-turut 10 mg/kgBB, 20 mg/kgBB, 40 mg/kgBB, dan 80 mg/kgBB. Hasil uji non parametrik Kruskal-Wallis ? = 0,05 menunjukkan bahwa dosis 10 mg/kgBB, 20 mg/kgBB, 40 mg/kgBB, dan 80 mg/kgBB berpengaruh terhadap kadar bilirubin total dan bilirubin direct. Hasil uji perbandingan berganda Dunnett T3 ? = 0,05 menunjukkan bahwa dosis-dosis tersebut tidak berbeda bermakna dengan KK1. Dengan demikian dosis-dosis tersebut memiliki efek kuratif karena dapat menurunkan kadar bilirubin total dan direct sampai mendekati kadar normal.

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This study was conducted in order to observe that the ethanol extract of mango ginger rhizome Curcuma mangga Val. affect the level of total bilirubin and direct bilirubin due to liver damage induced by tetrachloride carbon CCl4 . The test animals in the study were 24 male rats Rattus norvegicus L. of Sprague Dawley strain that was divided into six treatment KK1, KK2, KP1, KP2, KP3 and KP4 and repeated four times. The KK1 group is a normal control group that was not injected with CCl4 and 0.5 CMC fed, KK2 group is a treatment group that was intraperitoneally injected with CCl4 treatment in the amount of 1 ml kgBW and 0.5 CMC fed. KP1, KP2, KP3 and KP4 are treatment groups that got injected with CCl4 1 ml kgBB and were given mango ginger rhizome ethanol extract each with a dose of 10 mg kgBW, 20 mg kgBW, 40 mg kgBW, and 80 mg kgBW respectively by oral. The results of Kruskal Wallis non parametric test 0,05 shows that the dose of 10 mg kgBW, 20 mg kgBW, 40 mg kgBW, and 80 mg kgBW impacted on total bilirubin and direct bilirubin levels. Dunnet rsquo s T3 0,05 multiple comparison test result shows that the dosages had no significant differences with KK1 group. In conclusions, the dosages could be deemed as have curative effects since they successfully reduce the level of total bilirubin and direct bilirubin until it approached normal level."

"[ABSTRAKDuh tubuh vagina adalah cairan yang keluar dari alat genital perempuan yang tidak berupa darah. World Health Organization (2007) merekomendasikan dalam menegakkan diagnosis duh tubuh vagina dengan menggunakan alur pemeriksaan dengan spekulum. Kementerian Kesehatan Republik Indonesia telah merekomendasikan alur tersebut untuk seluruh puskesmas di Indonesia. Penelitian ini bertujuan untuk mengetahui nilai sensitivitas dan spesifisitas alur pemeriksaan duh tubuh vagina dengan spekulum oleh dokter puskesmas di Kota Pontianak yang dikonfirmasi dengan pemeriksaan laboratorium. Uji diagnostik sensitivitas dan spesifisitas dilakukan terhadap 52 subyek penelitian. Hasil penelitian menunjukkan nilai sensitivitas dan spesifisitas diagnosis vaginitis menggunakan spekulum sebesar 57,1% dan 52%, sedangkan sensitivitas dan spesifisitas untuk diagnosis servisitis sebesar 75% dan 57,7%. Hal tersebut menunjukkan nilai sensitivitas dan spesifisitas yang rendah (≤85%), menunjukkan bahwa pemeriksaan menggunakan spekulum tidak cukup baik untuk digunakan sebagai dasar dalam menegakkan diagnosis duh tubuh vagina.

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ABSTRACTVaginal discharge is the discharge from womens genitals which does not consist of blood. World Health Organization in 2007 provide recommendations for diagnosis vaginal discharge in health care one of them by using a speculum. The Ministry of Health of Indonesia has recommended speculum examination of vaginal discharge to all health centers in Indonesia. This research aim was to study the sensitivity and specificity of vaginal discharge examination using a speculum by doctors in primary health care in Pontianak confirmed by laboratory examination. Sensitivity and specificity of diagnostic testing were conducted on 52 research subjects. The result of the study showed the sensitivity and specificity for the diagnosis of vaginitis using a speculum were 57.1% and 52%, whereas the sensitivity and specificity for the diagnosis of cervicitis were 75% and 57.7%. Low sensitivity and specificity values (≤85%), indicating that the use of a speculum examination is not good enough to be used as a basis in the diagnosis of vaginal discharge., Vaginal discharge is the discharge from womens genitals which does not consist of blood. World Health Organization in 2007 provide recommendations for diagnosis vaginal discharge in health care one of them by using a speculum. The Ministry of Health of Indonesia has recommended speculum examination of vaginal discharge to all health centers in Indonesia. This research aim was to study the sensitivity and specificity of vaginal discharge examination using a speculum by doctors in primary health care in Pontianak confirmed by laboratory examination. Sensitivity and specificity of diagnostic testing were conducted on 52 research subjects. The result of the study showed the sensitivity and specificity for the diagnosis of vaginitis using a speculum were 57.1% and 52%, whereas the sensitivity and specificity for the diagnosis of cervicitis were 75% and 57.7%. Low sensitivity and specificity values (≤85%), indicating that the use of a speculum examination is not good enough to be used as a basis in the diagnosis of vaginal discharge.]"

"Pendahuluan : Infeksi dengue merupakan masalah kesehatan utama di Indonesia yang berdampak pada kematian akibat renjatan, apabila diagnosis dan penatalaksanaan tidak dilakukan secara dini. Kendala yang dihadapi dalam protokol deteksi kebocoran plasma selama ini adalah faktor yang menyebabkan negatif palsu, waktu yang di perlukan relatif lama, serta waktu terjadinya kebocoran plasma yang tidak dapat dipastikan. Ultrasonografi abdomen menjadi alat diagnostik potensial untuk menilai kebocoran plasma dan menjadi indikator prognostik. Tujuan : Menghitung nilai sensitivitas dan spesifisitas ultrasonografi abdomen dalam mendeteksi kebocoran plasma pada infeksi dengue dewasa berdasarkan pemeriksaan albumin darah, serta mendapatkan karakteristik efusi pleura, asites dan penebalan dinding kandung empedu dalam ultrasonografi abdomen pada infeksi dengue. Metode : Penelitian ini menggunakan desain potong lintang ( cross sectional study ) serial dengan menggunakan data primer. Hasil : Pada hari ke 3 sampai hari ke 5 demam, ultrasonografi abdomen memiliki sensitivitas 100% dan spesifisitas 100%, sedangkan pada hari ke 6 didapatkan sensitivitas 100% dan spesifisitas 83,3% dibandingkan pemeriksaan albumin darah sebagai standar baku emas. Kesimpulan : Ultrasonografi abdomen dapat dimasukkan ke dalam protokol diagnostik infeksi dengue sebagai alternatif pemeriksaan albumin darah.

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Introduction : Dengue infection has been the major health issue in Indonesia, which may lead to death because of shock. The protocol in detecting plasma leakage have several problems that can make false negative. Abdominal ultrasound is a potential diagnostic modality in detecting this condition. There were no spesific studies to determine the role of ultrasound in dengue infection.

Objective : to asses the sensitivity and specificity of abdominal ultrasound in detecting plasma leakage of dengue infection compared to serum albumin and also to determine the characteristic of pleural effusion, ascites and thickening of gall bladder wall.

Method : This study is using serial cross sectional design with primary data.

Result : At third until fifth day of fever, the sensitivity and specificity of abdominal ultrasound is both 100%. At sixth day of fever, the sensitivity is 100% and the specificity is 83,3% compared to serum albumin.

Conclusion: Abdominal ultrasound can be implemented to diagnostic protocol of dengue infection as an alternative examination in detecting plasma leakage and should be performed at fourth and fifth day of fever."

"[ABSTRAKLatar Belakang: Kusta merupakan penyakit infeksi penyebab neuropati perifer paling sering. Neuropati otonom merupakan salah satu neuropati perifer yang perlu dideteksi dini dengan pemeriksaan sederhana untuk mencegah kecacatan lebih lanjut karena memiliki gejala subklinis. Tujuan: Menguji sensitivitas dan spesifisitas pemeriksaan Stimulated Skin Wrinkle (SSW) terhadap Sudoscan dalam mendeteksi neuropati otonom pada kusta multibasiler. Metode penelitian: Penelitian menggunakan uji diagnostik pemeriksaan SSW terhadap Sudoscan pada penderita kusta multibasiler yang telah didiagnosis di poliklinik Kulit dan Kelamin RS Cipto Mangunkusumo, Jakarta. Penelitian dilakukan selama tiga bulan (Maret-Mei 2015). Anamnesis, pemeriksaan fisik, SSW dengan krim Eutectic mixture of local anesthetic (EMLA), dan Sudoscan dilakukan pada setiap subjek penelitian. Hasil dianalisis untuk mendapatkan nilai sensitivitas dan spesifisitas. Hasil: Diperoleh 70 subyek penelitian. Prevalensi gangguan otonom berdasarkan pemeriksaan SSW, Sudoscan dan klinis berturut-turut sebesar 64.3%, 32.9% dan 85.7%. Berdasarkan kurva ROC pemeriksaan SSW terhadap Sudoscan, didapatkan nilai AUC sebesar 0,779. Setelah diuji dengan tabel 2x2 didapatkan nilai sensitivitas 95.7%, spesifisitas 51.1%, nilai prediksi positif 48.9% dan nilai prediksi negatif 96%. Kesimpulan: Pemeriksaan SSW dapat menjadi pemeriksaan penyaring yang sederhana dalam mendeteksi neuropati otonom pada kusta tipe multibasiler, dengan sensitivitas yang tinggi.

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ABSTRACTBackground: Leprosy is the commonest infectious disease causes peripheral neuropathy. Autonomic neuropathy is a peripheral neuropathy that is important to detect with a simple examination to prevent further disability because the subclinical manifestation. Objective: Examine the sensitivity and specificity of Stimulated Skin Wrinkle (SSW) examination against Sudoscan to detect autonomic neuropathy in multibacillary leprosy. Method: The study consists of diagnostic test of SSW examination upon Sudoscan among multibacillary leprosy patients previously diagnosed in the Dermatology & Venerealogy Clinic in Cipto Mangunkusumo Hospital, Jakarta. The study was conducted in three months (March-May 2015). History, physical examination, SSW with Eutectic mixture of local anesthetic (EMLA) cream, and Sudoscan was performed upon every subject. Results are analyzed to obtain sensitivity and specificity level. Results: There are 70 subjects participated. Prevalence of autonomic disturbance by SSW, Sudoscan and clinical are 64.3%, 32.9% and 85.7% respectively. Based on ROC curve of the SSW examination against Sudoscan, the obtained AUC value is 0.779. After testing with chi-square, the following values were obtained: sensitivity 95.7%, specificity 51.1%, positive predictive value 48.9%, and negative predictive value 96%. Conclusion: SSW examination is a simple screening test that can detect autonomic neuropathy among multibacillary leprosy, with high sensitivity.;Background: Leprosy is the commonest infectious disease causes peripheral neuropathy. Autonomic neuropathy is a peripheral neuropathy that is important to detect with a simple examination to prevent further disability because the subclinical manifestation. Objective: Examine the sensitivity and specificity of Stimulated Skin Wrinkle (SSW) examination against Sudoscan to detect autonomic neuropathy in multibacillary leprosy. Method: The study consists of diagnostic test of SSW examination upon Sudoscan among multibacillary leprosy patients previously diagnosed in the Dermatology & Venerealogy Clinic in Cipto Mangunkusumo Hospital, Jakarta. The study was conducted in three months (March-May 2015). History, physical examination, SSW with Eutectic mixture of local anesthetic (EMLA) cream, and Sudoscan was performed upon every subject. Results are analyzed to obtain sensitivity and specificity level. Results: There are 70 subjects participated. Prevalence of autonomic disturbance by SSW, Sudoscan and clinical are 64.3%, 32.9% and 85.7% respectively. Based on ROC curve of the SSW examination against Sudoscan, the obtained AUC value is 0.779. After testing with chi-square, the following values were obtained: sensitivity 95.7%, specificity 51.1%, positive predictive value 48.9%, and negative predictive value 96%. Conclusion: SSW examination is a simple screening test that can detect autonomic neuropathy among multibacillary leprosy, with high sensitivity., Background: Leprosy is the commonest infectious disease causes peripheral neuropathy. Autonomic neuropathy is a peripheral neuropathy that is important to detect with a simple examination to prevent further disability because the subclinical manifestation. Objective: Examine the sensitivity and specificity of Stimulated Skin Wrinkle (SSW) examination against Sudoscan to detect autonomic neuropathy in multibacillary leprosy. Method: The study consists of diagnostic test of SSW examination upon Sudoscan among multibacillary leprosy patients previously diagnosed in the Dermatology & Venerealogy Clinic in Cipto Mangunkusumo Hospital, Jakarta. The study was conducted in three months (March-May 2015). History, physical examination, SSW with Eutectic mixture of local anesthetic (EMLA) cream, and Sudoscan was performed upon every subject. Results are analyzed to obtain sensitivity and specificity level. Results: There are 70 subjects participated. Prevalence of autonomic disturbance by SSW, Sudoscan and clinical are 64.3%, 32.9% and 85.7% respectively. Based on ROC curve of the SSW examination against Sudoscan, the obtained AUC value is 0.779. After testing with chi-square, the following values were obtained: sensitivity 95.7%, specificity 51.1%, positive predictive value 48.9%, and negative predictive value 96%. Conclusion: SSW examination is a simple screening test that can detect autonomic neuropathy among multibacillary leprosy, with high sensitivity.]"

"Hiperbilirubinelnia merupakan fenomena klinis yang sering ditemukan pada bayibaru lahir. Tujuan penelitian untuk mengidentifikasi pengaruh perubahan posisitidur selama fototerapi terhadap rata-rata kadar bilirubin total. Desain penelitianadalah quasi experimental pre-post test with control group. Sampel yangdigunakan yaitu bayi baru lahir dengan hiperbilirubinemia, terdiri atas 20 bayikelompok intervensi dan 20 bayi kelompok kontrol. Analisis perbedaan kadarbilirubin total menggunakan independent t test. Hasil penelitian menunjukkantidak ada perbedaan yang bermakna pada kadar bilirubin total kelompok kontroldan kelompok intervensi, namun penurunan kadar biliiubin pada kelompokintervensi lebih cepat dari pada kelompok kontrol. Penelitian inimerekomendasikan perubahan posisi tidur dapat mempercepat penurunan kadarbilirubin total.

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AbstractHyperbilirubinemia is a clinical phenomenon that mostly appears to the newbornbaby. The purpose of the research is to identify the effect of changing sleepingposition during the phototherapy on the rate of total concentrate of bilirubin. Theresearch design was quasi experimental pre-post test with control group. Thesampel, was new born babies with hyperbilirubinemia; which were classified into20 babies in intervention group and 20 babies in controlled group. The analysis ofdifferent total bilirubin rate used independent t test showed that there was no anysignificant differences on the total of bilirubin rate in controlled group andintervention group. However, the total bilirubin rate reduction on the interventiongroup was faster than control group. This research reccomended that sleepingposition changes can decrease the total bilirubin rate fastly."

"Latar Belakang: Penelitian ini merupakan bagian dari penelitian jangka panjang mengenai kesehatan mental remaja. Studi pedahuluan dari penelitian ini menemukan fakta bahwa masalah gejala kecemasan menduduki peringkat pertama prevalensi 84.9 , berdasarkan hasil tes skrining menggunakan subskala kecemasan Hopkins Symptom Check List ndash; 25 HSCL-25. Tujuan: Untuk mengetahui sensitivitas dan spesifisitas pada subskala kecemasan HSCL-25 dalam mengidentifikasi kecemasan jika dibandingkan dengan gold standard berupa wawancara diagnostik, serta mengidentifikasi nilai cut-off yang tepat dalam penggunaan subskala kecemasan HSCL-25 pada populasi remaja. Metode: Membandingkan kecenderungan kecemasan berdasarkan hasil skrining HSCL-25 dengan hasil wawancara diagnostik menggunakan modul skrining Structured Clinical Interview for DSM-IV SCID sebagai acuan pembuatan gold standard. Proses penelitian menggunakan teknik double-blind dengan bantuan tim penelitian. Wawancara dilakukan kepada 40 orang remaja siswa SMA di wilayah DKI Jakarta, mengacu pada hasil skrining. Hasil: Subskala kecemasan HSCL-25 memiliki nilai sensitivitas sebesar 0.50 dan nilai spesifisitas sebesar 0.50. Skor cut-off HSCL-25 sebesar 1.75 yang digunakan dalam penelitian ini kurang ideal dalam mengidentifikasi individu dengan masalah kecemasan pada populasi remaja. Kesimpulan: Subskala kecemasan HSCL-25 memiliki kemampuan terbatas dalam mengidentifikasi kecemasan yang mengarah pada gangguan pada populasi remaja. Oleh sebab itu, HSCL-25 tidak disarankan sebagai alat skrining tunggal dalam mengukur kecenderungan gangguan kecemasan pada populasi ini. Terdapat pula kemungkinan bahwa gold standard yang dipilih dalam penelitian ini kurang sesuai sebagai pembanding HSCL-25. Penelitian selanjutnya diharapkan dapat mempersingkat interval waktu antara proses skrining dan wawancara, serta mempertimbangkan pemilihan gold standard yang lebih sesuai.

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Background: This study is part of a longitudinal study about adolescent's mental health. A preliminary study of this study found that anxiety symptoms were ranked first prevalence 84.9, based on screening using Hopkins Symptom Check List 25 HSCL 25 anxiety subscale.

Objective: To determine the sensitivity and specificity of the HSCL 25 anxiety subscale compared to the diagnostic interview as a gold standard, as well as identifying appropriate cut off score for HSCL 25 anxiety subscale in adolescent's population.

Methods: Comparing HSCL 25 anxiety score with the results of diagnostic interview using the Structured Clinical Interview for DSM IV SCID screening module as the gold standard. This study was conducted using double blind technique, and the blinding process was assisted by the research team. Interviews were conducted to 40 high school students in DKI Jakarta, based on screening results.

Results: Anxiety subscale of HSCL 25 has a 0.50 sensitivity and 0.50 specificity. The cut off score used in this study 1.75 is less than ideal in identifying individuals with anxiety problems in adolescent populations.

Conclusion: The anxiety subscale of HSCL 25 has limited ability to identify anxiety disorder in adolescent populations. Therefore, it is not recommended as a single screening tool in measuring the anxiety disorder trends in this population. It is also possible that the gold standard chosen in this study is less suitable as a comparison of HSCL 25. Further research is expected to shorten the time interval between the screening process and interviews, as well as consider more appropriate gold standard selection."