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Tamam Anugrah Tamsil
"Latar Belakang : Efusi pleura masif merupakan salah satu masalah pada tatalaksana kanker paru dan menyebabkan kematian. Pemasangan kateter intrapleura merupakan tatalaksana utama keganasan dengan efusi pleura masif. Kateter yang digunakan yaitu water sealed drainage, indwelling pleural catheter atau pigtail catheter. Water sealed drainage saat ini merupakan kateter yang terbanyak digunakan.
Tujuan : Penelitian ini adalah penelitian pendahuluan untuk mengetahui penggunaan (toleransi dan efikasi) water sealed drainage, indwelling pleural catheter dan pigtail catheter pada penatalaksanaan kanker paru dengan efusi pleura masif.
Metode : Penelitian observasional kohort retrospektif pada pasien kanker paru tegak jenis dengan efusi pleura masif yang terpasang kateter intrapleura (WSD, IPC atau pigtail catheter). Data diambil dari rekam medis Rumah Sakit Umum Pusat Persahabatan Jakarta pada periode 1 Januari 2012 sampai 31 Desember 2015 dan dilakukan penilaian tolerasi (komplikasi akut dan lanjut) dan efikasi (lama penggunaan, lama rawat dan alasan pencabutan) pemasangan kateter intrapleura.
Hasil : Subjek penelitian 77 pasien dengan karakteristik laki-laki (55,8%), median usia 57 tahun, range 26-84 tahun, adenokarsinoma (84,4%) dan terapi kemoterapi (32,5%). Komplikasi akut sebesar 70,1%, komplikasi terbanyak nyeri lokasi pemasangan kateter (58,4%). Komplikasi lanjut sebesar 54,5%, komplikasi terbanyak nyeri lokasi kateter bertambah atau menetap (29,9%). Rerata lama rawat pasca pemasangan kateter 14,14 hari, median 10 hari dan range 1-72 hari. Rerata lama pemakaian kateter 55,98 hari, median 30 hari dan range 2-310 hari. Alasan pencabutan kateter terbanyak adalah produksi cairan minimal (46,75%).
Kesimpulan : Toleransi dan efikasi penggunaan kateter intrapleura pada pasien kanker paru dengan efusi pleura masif cukup baik dan aman. Diperlukan penelitian kohort prospektif dengan jumlah sampel yang sama pada tiap kelompok kateter, sehingga penggunaan kateter dapat dianalisis perbandingannya dan penelitian dengan kelompok pembanding, contohnya tindakan pleurodesis, yang merupakan baku emas tatalaksana efusi pleura ganas.
Background : Massive pleural effusion is one of the problems in lung cancer treatment that cause death. The main treatment of cancer patient with massive pleural effusion is the placement of intrapleural catheter. Catheters that can be used are water sealed drainage, indwelling pleural catheter or pigtail catheter. Currently, water sealed drainage is the most catheter used.
Objective : This is a preliminary study which is aimed to assess tolerancies and efficacies of water sealed drainage, indwelling pleural catheter or pigtail catheter for treatment of lung cancer with massive pleural effusion.
Methods : This study is a retroscpective observational cohort study. Subjects are lung cancer patients with massive pleural effusion and catheterized with intrapleural catheter (WSD, IPC or pigtail catheter). The datas were taken from medical record at RSUP Persahabatan between 1 January 2012-31 December 2015 and assessed for tolerancies (acute or late complication) and efficacies ((length of hospital admission after catheter placement, duration and the reason of retraction) of intrapleural catheter
Results: Subjects of study are 77 patients, with characteristic, male (55,8%), median age 57 years old, range from 26 to 84 years old, adenocarcinoma (84,4%) and the most main therapy is chemotherapy (32,5%). Acute complication obtained in 70,1% patients, with the most common complication is pain in catheter location (58,4%). Late complication obtained in 54,5% patients with the most common complication is pain in the catheter location (29,9%). The mean of length of staying in hospital after the placement of catheter are 14,14 days, median 10 days, range from 1 to 72 days. The mean of duration of catheter placement is 55.98 days, median 30 days, range from 2 to 310 days. Minimal fluid production (46,75%) are the most reason of intrapleural catheter retraction.
Conclusion: Tolerancies and efficacies of intrapleural catheter (WSD, IPC or pigtail catheter) in lung cancer patients with massive pleural effusion are quite good and safe. Prospective cohort studies are needed in the future to determine which type of intrapleural catheter is better for the treatment of massive pleural effusion in lung cancer patients and studies with comparison group for example pleurodesis, which is the gold standard for treatment of malignant pleural effusion."
2016
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Jihan Luqmannul Khakim
"Latar belakang: Pemasangan indwelling pleural catheter (IPC) untuk efusi pleura maligna untuk mengeluarkan cairan pleura, memungkinkan paru-paru mengembang dan tercapai autopleurodesis. Di masa lalu, kami mendidik pasien untuk mendrainase kateter hanya ketika mereka merasa sesak, metode di bagian kami sekarang mendrainase kateter pleura yang ada di dalam tubuh secara terus-menerus setiap hari. Studi ini membandingkan autopleurodesis dan tingkat infeksi antara kateter pleural yang didrainase harian dan berkala.
Metode: Dilakukan penelitian kohort retrospektif. Subjek dipilih secara konsekutif di mana seluruh subjek yang telah didiagnosis EPM dan terbagi menjadi dua kelompok pasien dengan drainase harian dan drainase berkala. Subjek ditindaklanjuti selama 2 bulan, hasil utama adalah autopleurodesis. Hasil sekunder adalah durasi waktu antara pemasangan kateter pleura dan autopleurodesis serta tingkat infeksi antara dua kelompok. Uji chi-square atau fisher exact digunakan untuk analisis bivariat antara dua kelompok.
Hasil: Hasil: Antara Januari 2019 - Mei 2020 ada 56 subyek kasus kateter pleura yang menetap, 31 kasus dengan drainase berkala, 25 subjek dengan drainase harian. Autopleurodesis yang dicapai pada kelompok drainase harian secara signifikan lebih tinggi dibandingkan dengan kelompok drainase berkala (88% vs 22,5%, p = 0,001). Durasi waktu autopleurodesis yang dicapai secara signifikan lebih singkat pada drainase harian dibandingkan dengan drainase berkala (45 hari vs 93 hari, p = 0,000). Tak satu pun dari subyek mengalami infeksi.
Simpulan : Drainase IPC harian pada EPM lebih singkat mencapai autopleurodesis daripada drainase berkala. Kekhawatiran tingkat infeksi yang lebih tinggi dalam drainase berkelanjutan dari kateter pleura yang menetap tidak terjadi dalam penelitian ini.

Background: The indwelling pleural catheter for malignant pleural effusion drains the pleural fluid, allows the lung to expand and autopleurodesis is achieved. In the past time, we educate the patient to drain the catheter only when they feel dyspnea. The trend in our institution is now draining the indwelling pleural catheter daily drainage continuously connected to the bag. This study comparing the autopleurodesis and infection rate between the daily and intermittent drainage of indwelling pleural catheter.
Method: This was a retrospective cohort study. The subjects were selected consecutively. Two group of patients with daily drainage and intermittent drainage in the past time. Subjects were followed up for 2 months, the primary outcome is autopleurodesis. The secondary outcome was time duration between indwelling pleural catheter insertion and removal and infection rate between two groups. The chi-square or fisher exact test is used for bivariate analysis between two groups.
Results: Between January 2019 - Mei 2020 there were 56 subjects of indwelling pleural catheter cases, 31 cases with intermittent drainage, 25 subjects with daily drainage. The autopleurodesis achieved in the daily drainage group was significantly higher compared to the intermittent drainage group (88% vs 22,5%, p=0,001). Time duration of autopleurodesis achieved was significantly faster in the daily drainage compared to intermittent drainage (45 days vs 93 days, p=0,000). None of the subjects had infection.
Conclusions: Continuous drainage of the indwelling pleural catheter is better than intermittent drainage in achieving the autopleurodesis. Concern of higher infection rate in the continuous drainage of indwelling pleural catheter did not happen in the study.
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Depok: Fakultas Kedokteran Universitas Indonesia, 2020
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UI - Tesis Membership  Universitas Indonesia Library
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Alexander Randy Angianto
"ABSTRAK
Pleural effusion is a condition when there is an accumulation of fluid in pleural space. The condition may manifest in breathing impariment by limiting lung expansion space. Pleural effusion is suffered by more than 1.5 million people per year in America. A study held ini Persahabatan Hospital between 2010-2011 found 119 cases of pleural effusion, 42,8% was malignant pleural effusion. Pleural malignancy is the most common indication for thoracocentesis, thus must be considered in massive pleural effusion (MPE). Theraphy for MPE is palliative with the goal being relief of dyspnea. Treatment option for MPA are deteminded by several factors: symptoms and performance status of the patient, the primary tumor type and its response to systematic therapy, and degree of lung re-expansion following pleural fluid removal. In this case, we will present a case of malignant pleural effusion as an illustration in searching of evidence in comparing between pleurodesis and indwelling pleural catheter in management of malignant pleural effusion. "
Jakarta: Departement of Internal Medicine. Faculty of Medicine Universitas Indonesia, 2016
616 UI-JCHEST 3:1 (2016)
Artikel Jurnal  Universitas Indonesia Library
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Maria Devi Novarita
"Pendahuluan: Efusi pleura merupakan penyakit infeksi pernapasan yang dapat mempengaruhi fungsi paru, dengan pilihan terapi terbatas untuk memperbaiki compliance paru. Penelitian ini bertujuan mengevaluasi efek kombinasi deep breathing dan aromaterapi peppermint terhadap compliance paru pada pasien dengan efusi pleura yang menggunakan water seal drainage (WSD).
Metode: Studi kuasi-eksperimental ini melibatkan 30 pasien efusi pleura, dibagi ke dalam kelompok intervensi dan kontrol, masing-masing 15 orang. Kelompok intervensi menerima deep breathing dan aromaterapi peppermint tiga kali sehari selama 14 hari. Data diukur menggunakan spirometri sederhana untuk mengukur nilai forced vital capacity (FVC) dan forced expiratory volume in one second (FEV1). Analisis data dilakukan menggunakan uji Mann-Whitney untuk nilai FVC dan independent sample t-test untuk FEV1.
Hasil: Analisis statistik menunjukkan peningkatan signifikan dalam nilai forced vital capacity (FVC) di kelompok intervensi (p value: 0,004), tanpa perubahan signifikan dalam forced expiratory volume (FEV1) (p value: 0,111).
Kesimpulan: Kombinasi deep breathing dan aromaterapi peppermint efektif meningkatkan compliance paru dan mengurangi gejala pada pasien efusi pleura dengan WSD, menawarkan pendekatan terapeutik alternatif yang aman dan mudah diterapkan.

Introduction: Pleural effusion is a respiratory infection that can affect lung function, with limited therapeutic options to improve pulmonary compliance. This study aims to evaluate the effect of the combination of deep breathing and peppermint aromatherapy on pulmonary compliance in patients with pleural effusion using water seal drainage (WSD).
Methods: This quasi-experimental study involved 30 pleural effusion patients, divided into intervention and control groups, each consisting of 15 individuals. The intervention group received deep breathing exercises and peppermint aromatherapy three times a day for 14 days. Data were measured using spirometry for forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) values. Data analysis was performed using the Mann-Whitney test for FVC and the independent sample t-test for FEV1.
Results: Statistical analysis showed a significant increase in FVC values in the intervention group (p Value: 0.004), without significant changes in FEV1 (p Value: 0.111).
Conclusion: The combination of deep breathing and peppermint aromatherapy effectively improves pulmonary compliance and reduces symptoms in patients with pleural effusion using WSD, offering a safe and practical therapeutic alternative.
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Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2024
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UI - Tesis Membership  Universitas Indonesia Library
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Barry Arief Praba
"Infeksi saluran kemih (ISK) merupakan kelainan yang sering ditemukan, diderita oleh laki-laki dan perempuan, dan memiliki manifestasi klinis yang berbeda-beda. ISK seringkali menimbulkan morbiditas dan mortalitas yang signifikan. Agen-agen antimikroba yang memiliki kadar yang tinggi dalam jaringan dan urin, yang dapat dikonsumsi per oral, dan tidak nefrotoksik telah mengurangi secara signifikan perlunya hospitalisasi dalam penatalaksanaan infeksi. Instilasi aminoglikosida intravesika telah digunakan secara empiris sebagai terapi profilaksis untuk mengobati bakteriuria pada pasien dengan cedera medula spinalis yang menjalani kateterisasi intermiten secara bersih.
Sebuah studi klinis prospektif yang dilakukan di bangsal urologi RS Dr. Sardjito Yogyakarta, kami mempelajari pasien yang terpasang kateter uretra menetap. Pasien dibagi kedalam 2 kelompok. Pada kelompok pertama (28 pasien) dilakukan sekali pemberian instilasi Netilmicin 25 mg intravesika, pada kelompok kedua (28 pasien) tidak diberikan instilasi Netilmicin. Dilakukan urinalisis sesaat sebelum pemasangan kateter uretra dan 4 hari pasca pemasangan kateter. Dilakukan pemeriksaan urinalisis sebelum dan sesudah instilasi netilmisin. Data dan hasil dianalisis secara statistik deskriptif. Digunakan uji Chi square untuk membandingkan kedua kelompok. Penelitian ini menggunakan perangkat lunak SPSS 17.
Dilakukan analisis pada urinalisis kedua kelompok yang diambil 4 hari pasca instilasi netilmisin 25 mg. Pasien-pasien yang diteliti, median usia adalah 59 tahun (min 29; maks 81 tahun). Pada kelompok pertama, 22 pasien (78,5 %) tetap tidak terdapat ISK, 6 pasien (21,5 %) menderita ISK. Pada kelompok kedua kami dapatkan 4 pasien (14,3) tetap tanpa ISK, 24 pasien (85,7 %) menderita ISK. Perbedaan pada kedua kelompok berbeda secara statistik (p=0,0001). Instilasi netilmisin intravesika efektif untuk manajemen infeksi saluran kemih pada pasien-pasien dengan kateter menetap.

Urinary tract infections (UTIs) are common, affect men and women of all ages, and vary dramatically in their presentation and sequelae. They are a common cause of morbidity and can lead to significant mortality. New antimicrobial agents that achieve high urinary and tissue levels, that can be administered orally, and that are not nephrotoxic have significantly reduced the need for hospitalization for severe infection. Shorter-course therapy and prophylactic antimicrobial agents have reduced the morbidity and cost associated with recurrent cystitis in women. Intravesical instillation of aminoglycoside has been used empirically as prophylaxis and to treat bacilluria in spinal-cord-injured patients undergoing clean intermittent catheterization.
In a prospective clinical trial performed in the urologic ward of Dr. Sardjito Hospital, yogyakarta, Indonesia, we studied 56 patients who has indwelling urethral catheter more than 4 days. Patients were divided into two groups. In group 1 (28 patients) one-time intravesical instillation of Netilmicin 25 mg was administred, and in group 2 (28 patients) none were given any treatment. Urinalysis was evaluated before and after instillation of Netilmicin. Statistical data and results were studied using descriptive statistics as median (minimum and maximum). To compare the response to treatment, Chi-Square test was used in two groups. Consequently, the data were analyzed using the SPSS 17 software.
Urinalysis were evaluated in two groups 4 days after intravesical instillation of 50 mg netilmicin. The patients we studied, the median age 59 years old (min. 29; max. 81). In the first group we found 22 (78,5 %) patients still without UTI, 6 (21,5 %) patients with UTI, in the second group we found 4 (14,3 %) still without UTI, 24 (85,7 %) patients with UTI. The difference was statistically significant (p=0.0001). Intravesical instillation of netilmicin on patients with indwelliing urethral catheter were effective on preventing catheter-related UTI.
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2013
T58563
UI - Tesis Membership  Universitas Indonesia Library
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Hutapea, Andhika Tiurmaida
"[ABSTRAK
Tujuan : Untuk menentukan apakah PICC dan PIVC pada bayi berat lahir sangat rendah berbeda, yang merujuk pada: kejadian sepsis, Jumlah pemakaian kateter yang dibutuhkan untuk keseluruhan terapi intravena dan efisiensi biaya pemasangan akses vena. Metoda: desain potong lintang retrospektif terhadap rekam medis semua bayi dengan berat lahir sangat rendah yang mendapatkan akses vena di divisi neonatologi RSCM periode tahun 2012 - 2014. Hasil: terdapat 161 kelompok PICC dan 154 kelompok PIVC. Karakteristik kedua kelompok tidak didapatkan perbedaan yang signifikan (p > 0,05). Terdapat perbedaan yang signifikan antara 2 kelompok untuk jumlah pemakaian (p=0,000). Biaya yang dibutuhkan untuk pemasangan kateter berbeda bermakna pada kedua kelompok (p<0,28). Kejadian infeksi aliran darah lebih tinggi pada kelompok PIVC. Beberapa bayi memiliki lebih dari satu episode sepsis, terdapat perbedaan yang signifikan (p = .032). Simpulan: PICC lebih efektif dan efisien dibandingkan PIVC.

ABSTRACT
Background: To determine whether the PICC and PIVC in low birth weight infants differ on: the incidence of sepsis, the amount of catheter needed for the overall intravenous therapy, IV and the efficiency of cost on installation venous access. Methods: A cross-sectional retrospective design of the medical records of all infants with very low birth weight who gain venous access in neonatology division RSCM period 2012 to 2014. The comparison of proportions between groups were analyzed with SPSS of which P value <0.05 was considered statistically significant. Results: Characteristics of the two groups was not found significantly differences (p> 0.05). There are significant differences between the 2 groups for the number and the duration of the use (p = 0.000), the cost required for catheter (p <0.28) and the incidence of bloodstream infections was higher in the group PIVC. Some babies have more than one episode of sepsis, which are significantly different (p = .032). Conclusion: PICC is more effective and efficient then PIVC. , Background: To determine whether the PICC and PIVC in low birth weight infants differ on: the incidence of sepsis, the amount of catheter needed for the overall intravenous therapy, IV and the efficiency of cost on installation venous access. Methods: A cross-sectional retrospective design of the medical records of all infants with very low birth weight who gain venous access in neonatology division RSCM period 2012 to 2014. The comparison of proportions between groups were analyzed with SPSS of which P value <0.05 was considered statistically significant. Results: Characteristics of the two groups was not found significantly differences (p> 0.05). There are significant differences between the 2 groups for the number and the duration of the use (p = 0.000), the cost required for catheter (p <0.28) and the incidence of bloodstream infections was higher in the group PIVC. Some babies have more than one episode of sepsis, which are significantly different (p = .032). Conclusion: PICC is more effective and efficient then PIVC. ]"
Fakultas Kedokteran Universitas Indonesia, 2015
SP-PDF
UI - Tugas Akhir  Universitas Indonesia Library
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Fahamzah Mahsal
"Pendahuluan : Efusi pleura pada kanker paru merupakan salah satu faktor prognostik yang buruk dan menjadi dasar perubahan TNM sistem versi 7 yang menetapkan efusi pleura sebagai faktor metastasis. Efusi pleura malignan merupakan tanda keganasan stage lanjut dengan tingkat harapan hidup yang pendek, berkisar antara 3 hingga 12 bulan tergantung dari tipe dan stage penyakit pada saat di diagnosis.
Metode : Penelitian kohort retrospektif dari catatan medis pasien kanker paru di RSUP Persahabatan Jakarta periode 1 Januari 2010 ? 31 Desember 2011. Angka penderita kanker paru yang tercatat masuk bangsal perawatan pada periode 1 januari 2010 ? 31 desember 2011 adalah 729 pasien, penderita kanker paru disertai efusi pleura sebanyak 315 pasien. Penetapan sampel dengan rumus rules of thumb didapat 50 pasien dengan sitologi dan atau histopatologi positif dan 50 pasien dengan sitologi dan atau histopatologi negatif. Dengan analisis Kaplan Meier, hubungan antara hasil sitologi dan atau histopatologi dan hari tahan hidup ditelaah. Analisis multivariat dengan Cox Regression dilakukan untuk menelaah hubungan hasil sitologi dan atau histopatologi dan hari tahan hidup dengan pengaruh umur, jenis kelamin, jenis sel kanker, terapi kanker dan volume efusi pleura.
Hasil : Data dari seratus pasien kanker paru dikumpulkan untuk analisis. Median survival time untuk pasien dengan hasil sitologi positif lebih rendah dibandingkan dengan yang hasil sitologi negatif (21 vs 42 hari), begitu pula overall survival time (40.42 + 42.83 vs 104.88 + 164.63, p 0.01). Faktor jenis kelamin, umur dan volume efusi pleura tidak bermakna secara statistik terhadap angka tahan hidup jika dikaitkan dengan hasil sitologi dan atau histopatologi. Pasien yang mendapatkan terapi kanker menunjukkan peningkatan hari tahan hidup secara signifikan (Hazard ratio 0.157, 95% CI 0.092 ? 0.266, p <0.001). Penurunan hari tahan hidup ditemukan pada pasien dengan karsinoma sel kecil secara signifikan dibandingkan dengan pasien adenokarsinoma (Hazard ratio 17.685, 95% CI 2.155 ? 145.146, p 0.007).
Kesimpulan : Masa tahan hidup pasien kanker paru dengan efusi pleura sitologi dan atau histopatologi positif lebih pendek dibanding kelompok yang negatif. Faktor jenis kelamin, umur dan volume efusi pleura tidak berpengaruh pada hari tahan hidup, sedangkan faktor terapi dan jenis sel kanker berpengaruh secara signifikan dalam meningkatkan hari tahan hidup.

Introduction : Pleural effusion is one of the poor prognostic factors in lung cancer and initiates the change in the 7th TNM classification system, which sets pleural effusion as a metastatic factor. Malignant pleural effusion indicates an advanced stage of malignancy with a low life expectancy rate, ranging from 3 to 12 months depending on the type and stage of the disease at time diagnosis is confirm.
Method : A cohort retrospective was conducted using data from medical records of lung cancer patients in Persahabatan Hospital Jakarta period 1 January 2010-31 December 2011. Seven hundred and twenty nine lung cancer patients were included, among then 315 had pleural effusion. Using the rules of thumb, Sample of 50 patients with positive cytology and or histopathology and 50 patients with negative cytology and or histopathology was included in the study. By using Kaplan-Meier analysis, the relationship between the results of cytology and or histopathology and survival rate were examined. Further multivariate cox regression analysis was conducted to examine the relationship between the result of cytology and or histopathology and survival rate according to age, gender, type of cancer cell, cancer therapy and the volume of pleural effusion.
Result : Data from one hundred lung cancer patients were collected for analysis. Median survival time for patients with positive cytology was lower than those with a negative cytology result (21 vs 42 days), as well as overall survival time (40.42 vs. 42.83 + 104.88 + 164.63 days, p 0.01). Factors associated including sex, age and volume of pleural effusion do not have significant effect on the survival if associated with cytology and or histopathology results. Patients receiving cancer therapy showed a significant increase in the survival days (Hazard ratio 0.157, 95% CI 0.092-0.266, p <0.001). A significant decrease of survival days was found in patients with small cell carcinoma as compared to adenocarcinoma patients (Hazard ratio 17.685, 95% CI 2.155-145.146, p 0.007).
Conclusion : Positive cytology and or histopathology results significantly decreases the survival rate in lung cancer patients. Factors including sex, age and volume of pleural effusion has no effect on survival rate, whereas cancer therapy and type of cancer cell (adenocarcinoma) significantly improves survival rate.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2013
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Amanda Cherkayani Sejati
"Efusi pleura ganas (EPG) sebagai bentuk perluasan dari keganasan sering muncul pada penderita kanker paru, mempersulit penatalaksanaan kanker paru, dan membuat prognosis pasien memburuk dengan rerata angka ketahanan hidup 6 bulan. Penelitian ini bertujuan untuk melihat karakteristik dan ketahanan hidup pasien kanker paru dengan EPG di RS Kanker Dharmais Jakarta tahun 2009-2013. Desain penelitian ini adalah kohort longitudinal dengan analisis univariat dan ketahanan hidup. Sampel penelitian ini adalah pasien kanker paru dengan EPG (stadium IIIB atau IV) dari metastasis kanker paru berdasarkan pemeriksaan sitologi atau biopsi dan memiliki rekam medik lengkap.
Hasil penelitian menunjukkan bahwa rata-rata umur pasien adalah 58,73 tahun, berjenis kelamin laki-laki, tidak merokok, dan status pekerjaan terbanyak adalah pensiunan. Mayoritas pasien mengeluhkan gangguan respirasi saat pertama berobat, memiliki jenis sel kanker adenokarsinoma, sudah mencapai stadium IV, dan lokasi efusi berada di paru-paru kanan. Sekitar 68.5% pasien bertahan hidup 6 bulan setelah diagnosis dan median survival adalah 12,5 bulan. Diharapkan ada KIE bagi masyarakat, terutama terkait kebiasaan merokok dan ditujukan untuk populasi berisiko, mengenai kanker paru untuk mengurangi jumlah pasien yang baru berobat setelah kanker mencapai stadium lanjut.

Malignant pleural effusion (MPE) often appears in patients with lung cancer and deteroriates prognosis of patients with mean survival rate of 6 months. This study aims to look at the characteristics and survival of lung cancer patients with MPE (stage IIIB or IV) at Dharmais Cancer Hospital Jakarta in 2009-2013. Study design was longitudinal cohort with univariate and survival analysis. Sample was lung cancer patients with metastatic MPE based on cytology test or biopsy with complete medical record.
Results showed average age of patients was 58.73; most were male, nonsmoker, and pensioner. Majority of patients had respiratory disorder, adenocarcinoma cancer type, reached stage IV, and effusion in the right lung. Approximately 68.5% of patients surviving 6 months after diagnosis and median survival were 12.5 months. IEC is needed for community; especially population with lung cancer risk, to help reducing number of new patients seeking treatment after cancer reaches advanced stage.
"
Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2014
S56600
UI - Skripsi Membership  Universitas Indonesia Library
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Widya Sepalanita
"ABSTRAK
Bakteriuria banyak terjadi pada pasien yang dirawat menggunakan kateter urine
indwelling. Perawatan kateter urine indwelling merupakan upaya pencegahan terjadinya
bakteriuria. Penelitian bertujuan untuk mengetahui pengaruh perawatan kateter urine
indwelling model American Association of Critical Care Nurses (AACN) terhadap
kejadian bakteriuria. Metode penelitian adalah quasi experiment posttest only design
comparison. Pengambilan sampel menggunakan metode non probability sampling jenis
consecutive sampling. Hasil uji bivariat bahwa perawatan kateter urine indwelling model
AACN signifikan menurunkan bakteriuria dibandingkan kelompok kontrol (OR 6,75,
p=0,038). Direkomendasikan kepada institusi pelayanan keperawatan bahwa perawatan
kateter urine indwelling model AACN perlu dijadikan acuan dalam pengembangan standar
prosedur operasional.

ABSTRACT
Bacteriuria is common in patients treated with indwelling urinary catheters. Indwelling
urinary catheter care prevents bacteriuria incidence. The study aims to determine the
effect of indwelling urinary catheter care with American Association of Critical Care
Nurses (AACN) model on the incidence of bacteriuria. The research method was a quasiexperiment
posttest only design comparison. Sampling shared used non-probability
sampling type of consecutive sampling. The results showed that the indwelling urinary
catheter care with AACN model significantly reduce bacteriuria compared to the control
group (OR 6.75, p=0.038). Recommendation for nursing care institutions is indwelling
urinary catheters care AACN model should be used as a reference in the development of
standard operating procedures."
2012
T30982
UI - Tesis Open  Universitas Indonesia Library
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Philadelphia: Elsevier Saunders, 2015
617.412 CAT
Buku Teks SO  Universitas Indonesia Library
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