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"Focused manuscript on the potential use/role of miRNAs in bioprocessing, specifically the production of complex proteins in mammalian cells. With that in mind I propose a draft list of topics/chapters along the following lines, intro on CHO/bioprocessing/engineering challenges to set scene, genomic organization, biogenesis and mode of action, Identifying miRNA targets, computational prediction, transcriptomics, proteomices, UTR analysis, etc., miRNA expression in Chinese hamster ovary cells, miRNAs as engineering targets: pathway manipulation to impact bioprocess phenotypes, miRNAs as biomarkers, detection methods : northern, PCR, hybridization arrays, next gen seq, manipulation of expression in cultured cells : transient/stable disregulation, knockout."

"Precise regulation of gene expression in both time and space is vital to plant growth, development and adaptation to biotic and abiotic stress conditions. This is achieved by multiple mechanisms, with perhaps the most important control being exerted at the level of transcription. However, with the recent discovery of microRNAs another ubiquitous mode of gene regulation that occurs at the post-transcriptional level has been identified. MicroRNAs can silence gene expression by targeting complementary or partially complementary mRNAs for degradation or translational inhibition. Recent studies have revealed that microRNAs play fundamental roles in plant growth and development, as well as in adaptation to biotic and abiotic stresses. This book highlights the roles of individual miRNAs that control and regulate diverse aspects of plant processes."

"This book gives an overview of commonly-used disposables in the manufacture of biopharmaceuticals, their working principles, characteristics, engineering aspects, economics, and applications. With this information, readers will be able to come to an easier decision for or against disposable alternatives and to choose the appropriate system. The book is divided into two parts. The first is related to basic knowledge about disposable equipment; and the second discusses applications through case studies that illustrate manufacturing, quality assurance, and environmental influence."

"ABSTRAKSaat ini persaingan didunia Industri semakin meningkat, efisiensi produksi umumnya dianggap sebagai kunci untuk sukses. Efisiensi produksi meliputi area yang luas seperti kecepatan, dimana peralatan produksi dan line produksi dapat di set untuk membuat suatu produk, menurunkan biaya material dan upah kerja dari suatu produksi, meningkatkan kualitas dan menurunkan reject, meminimalkan downtime dari mesin produksi, biaya perawatan produksi murah. Programmable Logic Controller memenuhi kebanyakan dari persyaratan diatas dan merupakan salah satu kunci dalam meningkatkan efesiensi produksi dalam industri. Dalam skripsi ini akan dibahas cara kerja sistem pada Alat Bantu Pengukur Ballast yang sudah ada, pembuatan sistem pengembangan pada Alat Bantu Pengukur Ballast dengan menggunakan PLC diagram ladder sebagai programnya dan membuat model pengembangan dari Alat Bantu Pengukur Ballast berbasis Programmable Logic Control.

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ABSTRACTCurrently the industry is increasing competition in the world, the production efficiency is generally regarded as the key to success. Efficiency of production includes a large area such as speed, where production equipment and production line can be set to make a product, lowering the cost of materials and wages of a production, improve quality and lower reject, minimize downtime of the production machine, production maintenance costs low. Programmable Logic Controller meets most of the requirements above and is one key to improving the efficiency of production in the industry. In this paper will discuss how the system works in Ballast Measuring Tools that already exists, the manufacturing system development in Ballast Measuring Tools by using PLC ladder diagram as a program and make a model of development based Ballast Measuring Tools Programmable Logic Control."