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"This book provides a timely overview of toxicogenomics, with special emphasis on the practical applications of this technology to the risk assessment process. Introductory sections are followed by a series of chapters highlighting practical and systematic applications of toxicogenomics in informing the risk assessment process, including the areas of mutagenicity, carcinogenicity, endocrine toxicity, organ, specific toxicity, population monitoring, and ecotoxicology. The book concludes with approaches for the integration of this technology in safety evaluation studies, and an outlook on how toxicogenomics and complementary technologies can reframe the current risk assessment paradigm."

"Toxicogenomics is the integration of genomics to toxicology. This technology is a powerful tool for collecting information from a large number of biological samples simultaneously and thus it is very useful for large-scale screening of potential toxicants.Toxicogenomics : a powerful tool for toxicity assessment provides up-to-date state-of-the-art information presented by the recognized experts, and is therefore an authoritative source of current knowledge in this field of research. The potential link between toxicology, genetics and human diseases makes this book very useful to investigators in many and varied disciplines of science and toxicology. "

"This book, written by two outstanding scientists in the field, describes the basic principles of toxic mechanisms and organ toxicity, providing detailed information on specific mechanisms or chemicals for exemplification. The goal is to provide sufficient information that the reader becomes familiar with the basic concepts in toxicology to enable him or her to understand the basic principles in toxicology and to evaluate the risks at given exposures. With this basic understanding the reader also will be able to critically evaluate the available information on a chemical and to identify data gaps."

"Immunotoxicology is a highly specialized discipline that addresses potential adverse effects on the immune system, including immunosuppression, immunogenicity, hypersensitivity and other immune system functional disorders. A broad spectrum of xenobiotics, including agents present in our environment as well as pharmaceutical molecules may adversely affect the immune system."

"With a weight-of-the-evidence approach, cancer risk assessment indentifies hazards, determines dose-response relationships, and assesses exposure to characterize the true risk. This book focuses on the quantitative methods for conducting chemical cancer risk assessments for solvents, metals, mixtures, and nanoparticles. It links these to the basic toxicology and biology of cancer, along with the impacts on regulatory guidelines and standards. By providing insightful perspective, Cancer Risk Assessment helps researchers develop a discriminate eye when it comes to interpreting data accurately and separating relevant information from erroneous."

"Penilaian risiko kesehatan terkait pajanan bahaya kimia merupakan penilaian yang dilakukan untuk memastikan bahwa risiko kesehatan yang disebabkan oleh pajanan bahaya kimia telah dikendalikan dengan tepat. Penelitian ini mendiskusikan tentang metode penilaian risiko kesehatan terkait pajanan bahaya kimia yang dikembangkan oleh negara, meliputi chemical health risk assessment (CHRA) dari Malaysia, control of substances hazardous to health (COSHH) oleh United Kingdom, semi-quantitative risk assessment (SQRA) dari Singapura dan semi-quantitative occupational risk prediction model (SQORPM) dari Taiwan. Metode yang digunakan dalam penelitian adalah kajian pustaka naratif yang bertujuan untuk mengidentifikasi cara penilaian, variabel yang digunakan, hubungan antar variabel serta analisis perbandingan umum dari empat metode dengan pendekatan argumentasi penulis. Keempat metode menggunakan variabel yang sama dalam menilai risiko, yakni variabel tingkat bahaya dan tingkat pajanan dan metode CHRA dan SQRA memiliki kesamaan dalam penentuan tingkat risiko. SQORPM menggunakan variabel toxicity index (TI), exposure index (EI) dan protection deficiency index (PDI). COSHH merupakan metode kualittatif dimana tingkat bahaya bersifat lebih umum, dan tingkat pajanan bahaya ditentukan oleh jumlah bahan kimia yang digunakan dan kemungkinan terdispersi ke udara. Menurut pendapat peneliti, CHRA yang dikembangkan oleh Malaysia merupakan metode yang tepat untuk digunakan di Indonesia karena matriks tingkat risiko yang diadopsi hampir sama.

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Health risk assessment related to chemical hazard exposure is an assessment carried out to ensure that the health risks caused by chemical hazard exposure have been properly controlled. This study discusses the method of assessing health risks related to exposure to chemical hazards developed by the state, including chemical health risk assessment (CHRA) from Malaysia, control of substances hazardous to health (COSHH) by the United Kingdom, semi-quantitative risk assessment (SQRA) from Singapore and semi-quantitative occupational risk prediction model (SQORPM) from Taiwan. The method used in this research is a narrative literature review which aims to identify the method of assessment, the variables used, the relationship between variables and general comparative analysis of the four methods with the author's argumentation approach. The four methods use the same variables in assessing risk, namely the variable level of hazard and level of exposure and the CHRA and SQRA methods have similarities in determining the level of risk. SQORPM uses the toxicity index (TI), exposure index (EI) and protection deficiency index (PDI) variables. COSHH is a qualitative method where the level of hazard is more general, and the level of hazard exposure is determined by the amount of the chemical used and the possibility of dispersal into the air. In the opinion of the researcher, the CHRA developed by Malaysia is the right method to be used in Indonesia because the risk level matrix adopted is almost the same."