Pengaruh Pemberian Sinbiotik Terhadap Kadar Indoxyl Sulfate, Konstipasi dan Kualitas Hidup Akibat Konstipasi Pada Pasien Hemodialisis Kronik = Effects of Synbiotics Supplementation on Level of Indoxyl Sulfate, Constipation and Quality of Life Related to Constipation of Hemodialysis Patients