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"ABSTRAKDisertasi ini menilai dinamika perubahan IMT dan tekanan darah pada wanita pasca menopausedi Kota Bogor, dengan desain studi longitudinal dan kualitatif. Analisis data panel dilakukanpada data sekunder dari ldquo;Studi Kohor Faktor Risiko Penyakit Tidak Menular rdquo; dengan follow up2. Hasil penelitian pada wanita pasca menopause antara lain prevalensi hipertensi 66,1 daninsiden rate 5 kasus per 100 orang-tahun. Model fixed effect menemukan hubungan bermaknaantara perubahan IMT dengan perubahan sistolik dan diastolik. Dinamika IMT dengan sistolikdengan R2 within 2 . Setelah disesuaikan dengan tingkat aktifitas fisik, peningkatan 1 kg beratbadan pada normotensi telah meningkatkan tekanan darah sistolik 1,5 mmHg dan diastolik 0,9mmHg, pada hipertensi terkendali sistolik 2,7 mmHg dan diastolik 1,3 mmHg, pada hipertensitidak terkendali sistolik 3,7 mmHg dan diastolik 1,3 mmHg. Setelah disesuaikan dengan derajatmerokok, penurunan dinamika IMT 1 telah menurunkan sistolik sekitar 2-3 mmHgdibandingkan IMT stabil. Trigliserida berpotensi menjadi marker lipid baru, sedangkan faktorpsikososial dan merokok berkontribusi pada pengendalian hipertensi.

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ABSTRACTThis study aims at evaluating the dynamics of change in BMI and blood pressure ofpostmenopausal women in Bogor by using both longitudinal data and qualitative study.Analyzing the 2 years follow up panel data of A Cohort Study of Non Communicable Diseases rsquo Risk Factors rdquo , this study showed that the prevalence of hypertension in postmenopausal womenis 66.1 , while the incidence rate reaches 5 cases per 100 person years. The fixed effectestimations confirmed that changes in systolic and diastolic pressure would follow changes inBMI. Moreover, after controlling with a physical activity, this study still found that there isstrong correlation between dynamics of BMI and systolic pressure, Normotensive patientsexperienced 1 kg of weight gain will increase their systolic pressure by 1.5 mmHg, theirdiastolic pressure by 0.9 mmHg. Furthermore, patients with under controlled hypertension whoare experienced 1 kg of weight gain will increase their systolic pressure by 2.7 mmHg, diastolicpressure by 1.3 mmHg. In contrast, patients with uncontrolled hypertension would have highersystolic pressure 3.7 mmHg and diastolic pressure around 1.3 mmHg. By controlling smokingactivity, 1 reduction in dynamic BMI would lower a systolic pressure as much as 2 3 mmHgcompared to a stabilized BMI. Other findings of this study are that triglyceride serves apotential of new lipid marker,while psychosocial factors and smoking behavior could contributeto controlled hypertension."

"Latar belakang: Perawatan demensia dapat menimbulkan dampak negatif yang dialami oleh pelaku rawat keluarga. Intervensi keperawatan holistik pada pelaku rawat keluarga selama merawat lansia dengan demensia dapat mengurangi dampak negatif akibat merawat lansia dengan demensia. Tujuan: Penelitian bertujuan mengidentifikasi efektivitas model KASIH terhadap kualitas pengasuhan, beban pelaku rawat, salah perlakuan, dan fungsi kognitif lansia dengan demensia. Metodologi: Penelitian menggunakan penelitian operasional melibatkan 114 responden dengan pengambilan sampel dilakukan secara simple random sampling. Hasil : Hasil menunjukkan adanya perbedaan bermakna dari waktu ke waktu antara kelompok kontrol dan intervensi pada skor kualitas pengasuhan (nilai ρ .001), skor beban (nilai ρ .001), skor salah perlakuan (nilai ρ .001), dan skor fungsi kognitif (nilai ρ .001). Simpulan: Model KASIH mampu meningkatkan skor kualitas pengasuhan, menurunkan skor beban pelaku rawat keluarga dan salah perlakuan, serta memperlambat penurunan fungsi kognitif setelah evaluasi 2 bulan dan 4 bulan. Model KASIH dapat diadopsi untuk meningkatkan dampak positif pengasuhan lansia dengan demensia pada pelaku rawat keluarga dan lansia dengan demensia.

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Background: Dementia care can have a negative impact on family caregivers. Holistic nursing interventions for family caregivers while caring for the elderly with dementia can reduce the negative impact of caring for the elderly with dementia. Objectives: The study aimed to identify the effectiveness of the KASIH model on the quality of care, caregiver burden, mistreatment, and cognitive function of the elderly with dementia. Method: The study used operational research, involved 114 respondents which sampling was done by simple random sampling. Results: There were significant differences over time between the control and intervention groups on quality of care scores (ρ .001), burden scores (ρ .001), mistreatment scores (ρ .001), and cognitive function scores (ρ .001). Conclusion: The KASIH model improved caregiving quality scores, reduced family caregiver burden and mistreatment scores, and slowed cognitive function decline after 2-month and 4-month evaluations. The KASIH model can be adopted to increase the positive impact of caring for older people with dementia on family caregivers and older people with dementia."

"ndonesia termasuk negara dengan struktur penduduk menuju tua. Prevalensi periodontitis dan hendaya kognitif meningkat seiiring dengan meningkatnya populasi lanjut usia. Penelitian ini bertujuan untuk mendapatkan implikasi periodontitis terhadap hendaya kognitif melalui status periodontal dan komposisi mikrobiota subgingiva. Desain penelitian adalah kasus kontrol. Status kognitif diperiksa menggunakan instrumen Hopkins Verbal Learning Test dan Mini-Mental State Examination yang telah divalidasi. Pemeriksaan faktor risiko hendaya kognitif meliputi status periodontal (indeks plak, indeks kebersihan mulut, indeks perdarahan papila, jumlah gigi, unit gigi fungsional, dan tingkat keparahan periodontitis), faktor sosiodemografi, serta sistemik dan lingkungan. Komposisi mikrobiota subgingiva diperiksa dari cairan krevikular gingiva. Hasil penelitian menunjukkan bahwa indeks plak, indeks perdarahan papila, jumlah gigi, usia, lama pendidikan, dan status hipertensi merupakan faktor-faktor yang paling berperan terhadap status kognitif. Terdapat hubungan bermakna (p<0,05) antara semua variabel status periodontal dengan status kognitif. Terdapat keragaman mikrobiota subgingiva antara subjek periodontitis lansia yang hendaya kognitif dengan kognitif normal. Abundance Porphyromonas gingivalis dan Treponema denticola lebih tinggi pada subjek lansia hendaya kognitif. Berdasarkan hal ini, dapat disimpulkan bahwa periodontitis merupakan faktor risiko hendaya kognitif.

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Indonesia is a country with an aging population. The prevalence of periodontitis and cognitive impairment increases along with the increase in the elderly population. This study aims to obtain the implications of periodontitis on cognitive impairment through periodontal status and subgingival microbiota composition. The design of this study was case-control. Cognitive status was assessed using the Hopkins Verbal Learning Test and Mini-Mental State Examination instruments. Examination of risk factors for cognitive impairment includes periodontal status (plaque index, oral hygiene index, papilla bleeding index, number of teeth, functional tooth units, and severity of periodontitis), sociodemographic factors, also systemic and environmental. The composition of the subgingival microbiota was examined from the gingival crevicular fluid. The results showed that plaque index, papilla bleeding index, number of teeth, age, length of education, and hypertension status were the factors that most contributed to cognitive status. There was a significant correlation (p<0.05) between all variables of periodontal status and cognitive status. There was a diversity of subgingival microbiota between cognitively impaired with cognitively normal in elderly subjects. The abundance of Porphyromonas gingivalis and Treponema denticola was higher in cognitively impaired elderly subjects. It can be concluded that periodontitis is a risk factor for cognitive impairment."