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Harahap, Yahdiana
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The aim of this research is to find the method for analyze glimepiride and it?s metabolite. Glimepiride is the second generation of antidiabetic oral from the sulphonyl urea that works by stimulating the insulin secretion from beta cells of pancreas. Glimepiride is isolated from plasma the using chloroform. Using the high performance liquid chromatography method which include C18 reversed phase column, using mixture of methanol:water (50:50, v/v) as a mobile phase, flow rate 1.0 ml/minutes, ...
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Depok: Fakultas Farmasi Universitas Indonesia, 2006
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