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Abstrak :
Kurkumin, bahan aktif tanaman kurkuma diduga bermanfaat dalam pengobatan penyakit hati. Dalam penelitian terdahulu, diperlihatkan efek protektif kurkumin terhadap peroksidasi lipid dan swelling mitokondria yang diisolasi dari hati tikus karena pemberian t-butilhidroperoksida (t-BuOOH). Dalam penelitian ini, pemberian t-BuOOH 90 M menyebabkan mitokondria tidak dapat membentuk potensial transmembran (m). Kegagalan pembentukan potential transmembran diduga berhubungan dengan transisi permeabilitas dan apoptosis. Dari 3 dosis kurkumin yang dicoba (0,5 M, 2,5 M dan 5,0 M), ternyata kurkumin dosis 2,5 M dapat mencegah kegagalan pembentukan potensial transmembran akibat t-BuOOH (79,13 + 6,28%). Pemeriksaan elektroforesis protein mitokondria menunjukkan kurkumin 1000 M dapat mencegah agregasi protein yang terjadi akibat t-BuOOH. Dari penelitian ini diperlihatkan efek proteksi kurkumin terhadap kerusakan sistem pembentukan energi dan protein mitokondria yang disebabkan oleh t-BuOOH. (Med J Indones 2007; 16:139-45)

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Curcumin, an active ingredient of curcuma plant has been thought to be beneficial in the treatment of liver diseases. In the previous studies, we have shown the protective effects of curcumin against lipid peroxidation and swelling of the rat liver mitochondrial preparation induced by tert-butylhydroperoxide (t-BuOOH). In the present study, the administration of t-BuOOH of 90 M caused the mitochondria failed to generate a transmembrane potential (m). Of 3 doses of curcumin administered (0.5 M, 2.5 M dan 5.0 M) the maximum protective effect against failure to generate a transmembrane potential caused by t- BuOOH was obtained by 2.5 M of curcumin (79.13 + 6.28%). Further, curcumin of 1000 M could prevent protein aggregation formation caused by t-BuOOH in the electrophoretogram. This study shows the protective effects of curcumin against damaged of energy production system and protein of the mitochondria caused by t-BuOOH. (Med J Indones 2007; 16:139-45

Abstrak :
Tujuannya adalah untuk meneliti kerusahan kromosom pada sel mononuklir darah peroko. Dengan tujuan tersebut telah dilakukan skrining mikronukleus pada sampel darah-tepi perokok. Sampel yang beradal dari perokok yang sakit tidak diikut sertakan. Dari tiap sampel diperiksa 500 lekosit mononuklir yang mengembang dengan menggunakan mikroskop cahaya dengan pembesaran 400x. Dibuat tabulasi fekuensi distribusi subjek dengan mikronukleus 0, 1, 2, 3, 4 dan 5, menurut umur dan keadaan subyek. Dari 102 sampel, 5 tidak diikutsertakan dan hanya 97 yang dianalisis. Terdapat peningkatan mikronukleus berturut-turut pada 12.8%perokok normal yang bertempat tinggal di daerah tak terpolusi, 12.9% perokok dengan hipertesi yang bertempat tinggal di daerah tak terpolusi, 33.3% perokok normal yang bertempat tinggal di daerah terpolusi dan 25% perokok dengan hipertensi yang bertempat tinggal di daerah terpolusi. Dengan demikian, terdapat kecendrungan peningkatan mikronukleus pada perokok dalam usia produktif, penderita hipertensi dan orang yang bertempat tinggal di daerah terpolusi.

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The purpose was to assess chromosomal damage in blood mononuclear cells of smokers. Smoker's peripheral blood samples were screened for micronulclei. Samples from smokers who had an illness were excluded. From each sample, 500 swelled mononuclear leucocytes were screened using a light mcroscope, with 400x magnification. Frequency distribution of subjects having 0, 1, 2, 3, 4, and 5 micronuclei (MN) according to age and condition were tabulated. From the 102 samples, 5 were excluded, and only 97 were analyzed. There was an increase in MN count in 12.8 %, 12.9%, 33.3% and 25% of normal smokers living in unpolluted area, hypertensive smokers living in unpolluted area, normal smokers living in polluted area and hypertensive smokers living in polluted area, respectively. Therefore, there was a tendency of increasing MN count in smokers in the productive age group, hypertensive people, and people living in polluted area.

Abstrak :
Penelitian analisis perubahan penggunaan lahan telah dilakukan menggunakan metode penginderaan jauh (inderaja) dan sistem informasi geografis (SIG). Identifikasi peta perubahan penggunaan lahan dilakukan dengan menggunakan proses tumpang susun peta penggunaan lahan tahun 1990 (hasil digitasi skala 1:50.000) dan peta penggunaan lahan tahun 1997 hasil interpretasi citra Landsat TM (Thematic Mapper) tahun 1997 dengan koordinat UTM (Universal Transverse Mercator). Perbaikan kontras citra melalui perataan histogram dilakukan dengan teknik klasifikasi terawasi yang terbagi menjadi 7 (tujuh) klas (sawah, perkampungan, tegalan, industri, tambak, lapangan olah raga dan semak). Analisis perubahan penggunaan lahan dan tingkat pencemaran air sungai BOD (Biological Oxygen Demand), COD (Chemical Oxygen Demand) dan TSS (Total Suspended Solid) dilakukan dalam sistim informasi geografis hingga diperoleh database dengan format link spasial dan tabular. Perubahan penggunaan lahan dianalisis berdasarkan pembagian segmen mengacu arah kontur sepanjang Kali Surabaya. Hasil analisis memperlihatkan perubahan penggunaan lahan pada tahun 1990-1997 yakni sawah berkurang 5,72 %, perkampungan bertambah 15,16 %, tegalan bertambah 0,54 %, tambak berkurang 9,67 %, industri bertambah 36,67 % dan semak berkurang 26,67 %. Hasil analisis tingkat pencemaran air dengan regresi linier berganda menunjukkan BOD (koefisien determinan 56 %) dan TSS (koefisien determinan 65 %) masih dipengaruhi oleh perubahan penggunaan lahan, tidak demikian halnya dengan COD (koefisien determinan 24 %).

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Application of Remote Sensing and Geographic Information System Methods for Land Using Difference. Land using difference analysis has been done using remote sensing and Geographic Information System (GIS) methods. Identification of land using difference was conducted using map overlaying process of 1990s (digitized scalling 1:50.000) and 1997s land using map (interpreted from Landsat TM (Thematic Mapper) Image 1997) with UTM (Universal Transverse Mercator) coordinate. Image enhancement was done through histogram equalization with supervised classification devided into 7 classes: rice field, settlement, dry field, industry, pond, sport field and bush. Land using difference and river pollution BOD (Biological Oxygen Demand), COD (Chemical Oxygen Demand) and TSS (Total Suspended Solid) analysis were done through GIS to get database in spasial link and tabular format. Land using difference was done based on division segment of Kali Surabaya contour as reference. The result shows that there were changes on land using from 1990 until 1997 that rice field reduced by 5.72 %; settlement increased by 15,16 %; dry field increased by 0.54 %; industry increased by 36.67 % and bush reduced by 26.67 %. Water pollution analysis results which was done using multiple linier regression show both BOD (determinant coefficient 56 %) and TSS (determinant coefficient 65 %) are affected by difference in land using, but COD (determinant coefficient 24 %) is not affected.

Abstrak :
Aplikasi sepeda motor kini menjadi sarana transportasi yang populer di kota-kota besar di negara-negara berkembang. Hal ini karena tingginya tingkat mobilitas masyarakat dihadapkan pada tingginya tingkat kemacetan. Penelitian ini dilakukan untuk menguji pengaruh kualitas layanan terhadap e-WOM melalui kepuasan konsumen dengan menggunakan PLS SEM-path modeling Temuan empiris menunjukkan bahwa semua hipotesis yang diuji terbukti. Kualitas layanan memiliki pengaruh positif yang signifikan secara langsung terhadap kepuasan dan tidak langsung terhadap e-WOM. Selanjutnya, dari indikator kualitas layanan, indikator yang paling berpengaruh adalah interaksi pengemudi dengan konsumen. Temuan ini berbeda dengan transportasi umum yang tidak menggunakan aplikasi online dimana indikator fasilitas fisik memiliki pengaruh tertinggi yang membentuk persepsi konsumen terhadap kualitas layanan. Hasil penelitian ini ditutup dengan diskusi dan implikasi manajerial.

Abstrak :
Inhibitionactivity of ethyl acetate of kluwek fraction on the linoleic acid oxidation catalysed by lipoxygenase: study was carried out to observe the inhibition activity of ethyl acetate kluwek (fermented pangium edule reinw) fractions on the enzymatic oxidation of linoleic acid. The degree oxidation of sample was determined according to the PV and TBA methods. The most active fraction then was treated as the inhibitor for enzymatic oxidation of linoleic acid catalyzed by lipoxygenase (E.C. 1.13.11.12). Data analysis shown that the antioxidant activity of kluwek fraction was: fraction B> fractionC> fraction A> control. Enzymatic assay of fraction B gave a kinetic inhibition as an uncompetitive inhibitor with Ki=1.1294% v/v.Physicochemical analysis of its effect to the enzymatic oxidation rate was significantly different according to the PV and TBA values and compared to the control

Abstrak :
ABSTRAK
Based on the content of the galangal's essential oil which can be used as antimicroorganism, analgesic, and antiseptic characterized with inhibiting and destructing microorganism life process, it is predicted that there is a possibility of essential oil can be used for anti-inflammatory agent. Nitric-oxide (NO) is an unstable gas produced by cell such as macrophage and has the function as antimicroorganism. The aim of this study was to investigate whether essential oil of galangal components has an effect to the macrophage NO production, which stimulated by LPS E. coli. The both curative and preventive analysis using ANOVA showed that the NO productions differences were significant (p< 0,01). This study showed that the NO levels produced by murine macrophages induced by LPS E. coli were suppressed by essential oil in a dose dependent fashion, suggesting anti-inflammatory activities. Curatively, increased doses of the essential oil resulted in increased its anti-inflammatory functions. Five micro liter of the essential oil was preventively the most concentration as anti inflammation.

Abstrak :
ABSTRAK
This study aims to analyze the factors that influence the customers' decision in using Islamic banking in Tasikmalaya. This study uses a quantitative method. The data used in this study is primary data. Primary data was obtained from questionnaires distributed to a hundred customers of Islamic banking in Tasikmalaya. Analysis of data uses multiple linear regression and the results show that in partial the variable of profit sharing has significantly positive effect on the customers' decision to use islamic banking, the variable of religion quality has significantly positive effect on the customer's decision to use islamic banking, the variable of education has significantly positive effect on the customer's decision to use islamic banking,the variable of income doesn't have significantly positive effect on the customer's decision to use islamic banking and the variable of products and services have significantly positive effect on the customers' decision to use islamic banking in Tasikmalaya.

Abstrak :
ABSTRAK
Kunjungan wisatawan menuju daerah tujuan wisata didasari oleh dua hal, yaitu faktor pendorong dan faktor penarik. Salah satu faktor pendorongnya yaitu motivasi. Motivasi memiliki 4 tipe, yaitu fisik, budaya, interpersonal, dan status. Keempat motivasi ini menjadi dasar dalam perbedaan kunjungan wisatawan di tiap-tiap atraksi yang jenis kawasannya berbeda, yaitu homogen dan heterogen. Kawasan homogen dalam penelitian ini yaitu kawasan Candi Prambanan dan kawasan heterogennya yaitu kawasan Keraton Yogyakarta. Pengumpulan data dalam penelitian ini menggunakan metode kuota sampling dan wawancara. Data yang diambil berupa motivasi wisatawan. Berdasarkan hasil pengumpulan data dan analisis data, motivasi di tiap-tiap atraksi pada kawasan yang jenisnya berbeda kemudian menghasilkan perbedaan bentuk pola pergerakan di antara kedua kawasan.

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ABSTRACT
Tourist arrival to the tourist destinations is based on two things, the push and pull factors. One of the push factor is tourist motivation. Tourist motivation has 4 types, physical motivation, cultural motivation, interpersonal motivation, and status motivation. These four types of motivation become the basic of the tourist arrival differences in each attraction of different types of areas, such as homogeneous and heterogeneous. The homogeneous area in this research is Candi Prambanan area and the heterogenous area in this research is Keraton Yogyakarta area. To collect the data, this research is used quota sampling along with interview method. The data that is collected is tourist motivation. Based on the data collecting and data analysist, motivation in each of attractions of different type of areas then lead to the difference in forming the tourist travel pattern between the two regions that describe tourist movement.