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"The sixth edition of Structural Dynamics: Theory and Computation is the complete and comprehensive text in the field. It presents modern methods of analysis and techniques adaptable to computer programming clearly and easily. The book is ideal as a text for advanced undergraduates or graduate students taking a first course in structural dynamics. It is arranged in such a way that it can be used for a one or two-semester course, or span the undergraduate and graduate levels. In addition, this text will serve the practicing engineer as a primary reference.The text differs from the standard approach of other presentations in which topics are ordered by their mathematical complexity. This text is organized by the type of structural modeling. The author simplifies the subject by presenting a single degree-of-freedom system in the first chapters, then moves to systems with many degrees-of-freedom in the following chapters. Finally, the text moves to applications of the first chapters and special topics in structural dynamics.This revised textbook intends to provide enhanced learning materials for students to learn structural dynamics, ranging from basics to advanced topics, including their application. When a line-by-line programming language is included with solved problems, students can learn course materials easily and visualize the solved problems using a program. Among several programming languages, MATLAB® has been adopted by many academic institutions across several disciplines. Many educators and students in the U.S. and many international institutions can readily access MATLAB®, which has an appropriate programming language to solve and simulate problems in the textbook. It effectively allows matrix manipulations and plotting of data. Therefore, multi-degree-of freedom problems can be solved in conjunction with the finite element method using MATLAB®.The revised version will include:- solved 34 examples in Chapters 1 through 22 along with MALAB codes.- basics of earthquake design with current design codes (ASCE 7-16 and IBC 2018).- additional figures obtained from MATLAB codes to illustrate time-variant structural behavior and dynamic characteristics (e.g., time versus displacement and spectral chart).This text is essential for civil engineering students. Professional civil engineers will find it an ideal reference."

"ABSTRACTPURPOSE:Asthma is a heterogeneous disease characterized by various types of airway inflammation and obstruction. Therefore, it is classified into several subphenotypes, such as early onset atopic, obese non eosinophilic, benign, and eosinophilic asthma, using cluster analysis. A number of asthmatics frequently experience exacerbation over a longterm follow up period, but the exacerbation prone subphenotype has rarely been evaluated by cluster analysis. This prompted us to identify clusters reflecting asthma exacerbation. METHODS:A uniform cluster analysis method was applied to 259 adult asthmatics who were regularly followed up for over 1 year using 12 variables, selected on the basis of their contribution to asthma phenotypes. After clustering, clinical profiles and exacerbation rates during follow up were compared among the clusters. RESULTS:Four sub phenotypes were identified: cluster 1 was comprised of patients with early onset atopic asthma with preserved lung function, cluster 2 late onset non atopic asthma with impaired lung function, cluster 3 early onset atopic asthma with severely impaired lung function, and cluster 4 late onset non atopic asthma with well preserved lung function. The patients in clusters 2 and 3 were identified as exacerbation prone asthmatics, showing a higher risk of asthma exacerbation.CONCLUSIONS: Two different phenotypes of exacerbation prone asthma were identified among Korean asthmatics using cluster analysis; both were characterized by impaired lung function, but the age at asthma onset and atopic status were different between the two."