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Abstrak :
Tesis ini membahas tentang motif yang mempengaruhi khalayak untuk berpartisipasi dalam internet meme yang beredar pada sosial media Path. Teori utama yang digunakan yaitu Uses and Gratifications terkait motif dan konsep Participatory Culture. Teori Uses and Gratifications dipilih karena merupakan teori yang seringkali digunakan untuk media atau konten baru dari sudut pandang khalayak serta konsep Participatory Culture ini muncul dan berkembang pada era digital saat ini Penelitian ini menggunakan paradigm positivistik dengan pendekatan kuantitatif bersifat eksplanatif dan metodologi yang digunakan melalui survey. Penelitian ini menyimpulkan bahwa motif Entertainment dan Self-expression mempengaruhi khalayak untuk ikut berpartisipasi dalam internet meme di media sosial path, sedangkan motif socializing and community building tidak memiliki pengaruh namun tetap berhubungan. Sementara satu lagi yaitu motive informativeness ditemukan tidak berpengaruh dan tidak berhubungan dengan partisipasi internet meme. ......This Thesis discusses about motives that influence audience to participate in internet meme social media Path. This study employ motives from Uses and Gratifications theory as a main theory, also concept about Participatory Culture. Uses and Gratifications theory have been selected because this theory been often to explain about new media and new kind of content from audience point of view also the concept of Participatory Culture have been emerge and thrive in this digital era. This research uses positivistic paradigm with quantitative explanatory approach and using survey as a research method. The conclusion for this research is shows that some motive Entertainment and Self-expression influence audience to participate in internet meme social media path. Meanwhile Socializing and Community Building motive doesn’t have a significant influence to internet meme participation but both of them still have a connection. The another one Informativeness motive doesn’t have any connection nor influence to internet meme participation.

Abstrak :
[Merumuskan Learning Organization Melalui Analisis Budaya Keselamatan Pasien Dan Budaya Organisasi Di RS.Masmitra Langkah awal membangun keselamatan pasien adalah melakukan penilaian terhadap budaya keselamatan pasien yang mana diperlukan pengkajian budaya organisasi sebagai panduan dalam menerapkan keselamatan pasien. Penelitian deskriptif dengan metode kuantitatif potong lintang dilanjutkan metode kualitatif ini bertujuan mengukur budaya keselamatan pasien, mengidentifikasi profil budaya organisasi dan merumuskan learning organization untuk membangun keselamatan pasien di RS.Masmitra. Budaya Hierarchy didapati sebagai budaya organisasi yang dominan saat ini di RS.Masmitra yang membutuhkan manajemen pengetahuan dalam upaya transformasi budaya keselamatan pasien. Hal ini sejalan dengan hasil penelitian budaya keselamatan pasien yang menyatakan dimensi pembelajaran organisasi dan perbaikan berkelanjutan merupakan budaya terlemah di RS.Masmitra. Oleh karena itu, perumusan learning organization sangatlah tepat untuk membangun keselamatan pasien di RS.Masmitra. ...... Formulating Learning Organization Through Analysis of Patient Safety Culture and Organizational Culture In Masmitra Hospital The initial step to build patient safety is by conducting assessment to the existing patient safety culture where assessment of organizational culture shall become guidance in patient safety implementation. Descriptive study with cross-sectional quantitative method followed by qualitative method aims to measure patient safety culture, identify organizational culture profile and formulates learning organization to develop patient safety in Masmitra hospital. Hierarchy culture has been found as the dominant organizational culture exists in Masmitra hospital which requires knowledge management in an effort to transform the culture of patient safety. This is in line with the research result which explains dimensions of organizational learning and continuous improvement is the weakest culture in Masmitra hospital. Therefore, formulation of a learning organization is appropriate to develop patient safety in Masmitra hospital.;Formulating Learning Organization Through Analysis of Patient Safety Culture and Organizational Culture In Masmitra Hospital The initial step to build patient safety is by conducting assessment to the existing patient safety culture where assessment of organizational culture shall become guidance in patient safety implementation. Descriptive study with cross-sectional quantitative method followed by qualitative method aims to measure patient safety culture, identify organizational culture profile and formulates learning organization to develop patient safety in Masmitra hospital. Hierarchy culture has been found as the dominant organizational culture exists in Masmitra hospital which requires knowledge management in an effort to transform the culture of patient safety. This is in line with the research result which explains dimensions of organizational learning and continuous improvement is the weakest culture in Masmitra hospital. Therefore, formulation of a learning organization is appropriate to develop patient safety in Masmitra hospital.;Formulating Learning Organization Through Analysis of Patient Safety Culture and Organizational Culture In Masmitra Hospital The initial step to build patient safety is by conducting assessment to the existing patient safety culture where assessment of organizational culture shall become guidance in patient safety implementation. Descriptive study with cross-sectional quantitative method followed by qualitative method aims to measure patient safety culture, identify organizational culture profile and formulates learning organization to develop patient safety in Masmitra hospital. Hierarchy culture has been found as the dominant organizational culture exists in Masmitra hospital which requires knowledge management in an effort to transform the culture of patient safety. This is in line with the research result which explains dimensions of organizational learning and continuous improvement is the weakest culture in Masmitra hospital. Therefore, formulation of a learning organization is appropriate to develop patient safety in Masmitra hospital.;Formulating Learning Organization Through Analysis of Patient Safety Culture and Organizational Culture In Masmitra Hospital The initial step to build patient safety is by conducting assessment to the existing patient safety culture where assessment of organizational culture shall become guidance in patient safety implementation. Descriptive study with cross-sectional quantitative method followed by qualitative method aims to measure patient safety culture, identify organizational culture profile and formulates learning organization to develop patient safety in Masmitra hospital. Hierarchy culture has been found as the dominant organizational culture exists in Masmitra hospital which requires knowledge management in an effort to transform the culture of patient safety. This is in line with the research result which explains dimensions of organizational learning and continuous improvement is the weakest culture in Masmitra hospital. Therefore, formulation of a learning organization is appropriate to develop patient safety in Masmitra hospital., Formulating Learning Organization Through Analysis of Patient Safety Culture and Organizational Culture In Masmitra Hospital The initial step to build patient safety is by conducting assessment to the existing patient safety culture where assessment of organizational culture shall become guidance in patient safety implementation. Descriptive study with cross-sectional quantitative method followed by qualitative method aims to measure patient safety culture, identify organizational culture profile and formulates learning organization to develop patient safety in Masmitra hospital. Hierarchy culture has been found as the dominant organizational culture exists in Masmitra hospital which requires knowledge management in an effort to transform the culture of patient safety. This is in line with the research result which explains dimensions of organizational learning and continuous improvement is the weakest culture in Masmitra hospital. Therefore, formulation of a learning organization is appropriate to develop patient safety in Masmitra hospital.]

Abstrak :
Proses pemulangan pasien di Rumah Sakit Masmitra saat ini masih belum optimal, oleh karena belum ada alur yang menggambarkan proses pemulangan pasien secara menyeluruh. Dengan mengaplikasikan Konsep Lean, dilakukan pemetaan aliran nilai kondisi sekarang (Value Stream Map) yang menunjukkan bahwa pada proses pemulangan pasien terdapat 41 kegiatan dan hanya 51 % bersifat Value Added, dan tentu saja mempunyai implikasi adanya pemborosan. Dari hasil analisis akar masalah diperoleh ide-ide perbaikan, kemudian dilakukan desain ulang kedalam alur proses baru yang dianggap ideal menghasilkan total hanya 17 kegiatan, 83 % diantaranya bersifat Value Added. Dengan diterapkannya Konsep Lean di RS Masmitra, diharapkan efisiensi juga akan terjadi bila pekerjaan dilakukan sesuai dengan apa yang dibutuhkan oleh pasien, tepat waktu, tepat ukuran dan tepat sasaran.

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The process discharge of patients in hospital Masmitra is still not optimal, because there is no groove that describes the process of returning the patient as a whole. By applying the concept of Lean, value stream mapping current conditions which shows that the process of returning patients there were 41 activities and only 51% are value added, and of course has implications for wastage. From the analysis of the root causes of acquired ideas repair, and then carried into the re-design of the new process flow is considered ideal to produce a total of only 17 activities, 83% of which is value added. With the implementation of Lean Concept in RS Masmitra, expected efficiency will also occur when the work is done in accordance with what is required by the patient, right time, the right size and right on target.

Abstrak :
Penelitian ini menganalisis hubungan kejadian burnout syndrome pada perawat di unit rawat inap dan unit rawat jalan RS “X” Bandar Lampung tahun 2013. Disain penelitian ini potong lintang dengan menggunakan pendekatan kuantitatif dan kualitatif. Data diperoleh dengan menggunakan kuesioner dari 239 perawat serta 5 orang informan. Kuesioner yang digunakan adalah Maslach Burnout Inventory dan survei diagnosis stres. Hasil penelitian didapatkan 21,8% perawat unit rawat inap dan 10,8% perawat rawat jalan mengalami burnout syndrome dan menunjukan tingginya kelelahan emosional dan rendahnya depersonalisasi. Kesimpulan : Sebagian besar perawat mengalami burnout syndrome derajat tinggi. Pengurangan kejadian burnout syndrome dapat dilakukan dengan cara peningkatan SDM, berupa peningkatan pendidikan dan pelatihan serta pengaturan jam kerja. ......This research analyzed burnout syndrome on nurses worked in in-patient units and out-patient units in “X” Hospital in Bandar Lampung in 2013. This was cross-sectional study with quantitative and qualitative approaches. Data were collected through a questionnaire survey of 239 nurses and 5 informant. This research used Maslach Burnout Syndrome and Survey Diagnostic Stress questionnaire. The results showed 21,8% nurses in in-patient units and 10,8% nurses in out-patient units having burnout syndrome and exhibited higher emotional exhaustion and lower depersonalization. Conclusion: Majority nurses were experienced high level of burnout. To reduced burnout syndrome can be solved by increasing resources, such as improving training and skills also providing reasonable work hour.

Abstrak :
Campak merupakan pcnyakit yang sanngat menular dan sebagai penyebab utama kcmatian anak di negara berkumbang termasuk Indonesia. Imunisasi campak di Indonesia telah berhasil dilaksanakan dengan baik. Namun kenyataannya masih banyak ditemukan kasus campak dibeberapa daerah. Salah satu fhklor yang diduga menjadi penycbabnya adalah daya guna vaksin yang tidak maksimal dikarenakan sistcm rantai vaksin yang sangat nncncnwkan untuk pcngamanan mulu valcsin tidak berfungsi clengall baik atau para pemgns inumisasi tidak melakukan pcnanganan vzlksin sesuai dengan yang tclah dilentukan. Bcrdasarkan atas kcnyataan ini, dilakukan penelilian mengcnai faktor-faktor yang berhubungan dcngan kepaluhan petugas imunisasi tcrhadap Standar Proscdur Operasional imunisasi dalam penanganan vaksin campak di Kabupaten Kebumen pada tahun 2009, yang terdiri atas bcbcrapa variabel, antara lain: pendidikan, pelatihan, Jama kerja, pengelahuan, sikap, motivasi, imbalan, persepsi kepcmimpinan, supervisi dan sarana. Penclilian menggunakan pcndekatan kuantitatiii dilakukan secara cross sectional dcngan sampel seluruh total pnpulasi sebanynk 69 responden, scrta menggunakan data primer yang diperoleh melalui observasi dan wawancara. I-lasil peneliiian mcnunjukkan responden yang memiliki kepatuhan adalah sebanyak 42 responden (6O,9%). Selanjutnya variabel indcpenden yang mcmiliki hubungan yang bermakna sccara statistik dcngan kepatuhan petugas, antara Iain: pendidikan, pengetahuan, imbalan dan sarana. Adapnn faktor yang paling dominan bcrhungan dcngan kepaluhan petugas adalah pcngelahuan dan sarana. l`|`lilSiI`|g'l1`|flSil'1g didapntkan nilai OR scbcsar 5,|95 dan 5,2872 ......Measles is one of infectious disease which is primary cause of death among children in developing countries, including Indonesia. Measles immunization program in Indonesia has been done well enough, but there are still many cases of measles found in several areas. One of suspected factors is vaeci|1e’s efficiency is not optimum caused by the chain system of vaccine which is important aspect in vaccine’s quality was not well functioned or vaccine ofdcer did not administered vaccine as procedures. Based on this facts, this study objective is to lind out factors which related to vaccine ofticer’s obedient to standard operating procedure of immunization on administrating measles vaccine in District of Kebumen year of 2009. Variables of this study are education, training, work duration, knowledge, attitude, motivation, fee, leadership perception, supervision and facility. This study is quantitative approach using the cross sectional method with from total population which are 69 respondents also taken primary data by observation and interview. The result of this study shows that 42 respondents (60,9%) have obedience. The independent variables which have statisticaliy signilicant related to ofiicer’s obedient are education, knowledge, fee and facility. 'I`he dominant factors which related to officers obedient are knowledge and facility, with OR are 5,l95 and 5,287 respectively.

Abstrak :
Karies gigi merupakan salah satu penyakit gigi dan mulut yang banyak dialami khususnya oleh anak umur sekolah dasar. Kejadian karies gigi pada anak diukur melalui indeks DMFT. Karies gigi berkaitan erat dengan kebiasaan anak SD dalam mengkonsumsi makanan kariogenik. Di Kota Serang, jumlah siswa SD yang menderita karies gigi tertinggi yaitu berada di wilayah kerja Puskesmas Taktakan. Tujuan penelitian ini adalah mengetahui hubungan karakteristik siswa dan perilaku konsumsi makanan kariogenik dengan kejadian karies gigi pada siswa umur 11-12 tahun di SDN terpilih wilayah kerja Puskesmas Taktakan Kota Serang tahun 2015, meliputi karakteristik (jenis kelamin, uang saku, pengetahuan, sikap, pH saliva), perilaku siswa (konsumsi makanan kariogenik, kebiasaan menggosok gigi, cara menggosok gigi yang benar). Metode yang digunakan dalam penelitian ini adalah menggunakan rancangan penelitian Cross Sectional. Penelitian dilaksanakan di SDN terpilih yang berada di wilayah kerja Puskesmas Taktakan Kota Serang dengan memakai teknik cluster random sampling yaitu SDN Drangong I, SDN I Taktakan, dan SDN Pereng. Hasil penghitungan besar sampel diperoleh sebanyak 140 orang. Pengumpulan data menggunakan kuesioner, pemeriksaan gigi, pengukuran pH saliva dan observasi cara menyikat gigi yang benar. Analisis data dilakukan dengan analisis univariat, uji bivariat dengan uji Kai Kuadrat, dan multivariat dengan Regresi Logistik. Hasil rekapitulasi indeks DMFT bahwa frekuensi DMFT terbanyak berada pada SDN Drangong I dan SDN Pereng termasuk tingkat keparahan karies gigi tinggi. Sedangkan SDN 1 Taktakan termasuk dalam tingkat keparahan karies gigi rendah. Makanan kariogenik yang paling sering dikonsumsi siswa adalah makanan kariogeniknya tinggi yang berbentuk padat lengket dan manis. Variabel yang mempunyai hubungan bermakna dengan kejadian karies gigi dengan p value < 0,05 adalah variabel uang saku, variabel pengetahuan, variabel sikap, variabel kebiasaan menggosok gigi, variabel cara menggosok gigi yang benar, dan variabel konsumsi makanan kariogenik, sedangkan variabel yang tidak memiliki hubungan bemakna dengan kejadian karies gigi dengan p value > 0,05 adalah variabel jenis kelamin dan variabel pH saliva. Faktor paling dominan adalah variabel konsumsi makanan kariogenik berhubungan dengan kejadian karies gigi. Sedangkan variabel pengganggu yaitu variabel kebiasaan menggosok gigi dan cara menggosok gigi yang benar. Saran bagi siswa dapat membawa bekal makanan yang tidak terlalu manis dan lengket, selain pemeriksaan gigi rutin pada semua siswa Puskesmas Taktakan bekerja sama dengan pihak sekolah untuk memberikan penyuluhan kepada orangtua siswa tentang kesehatan gigi anaknya terutama mengenai waktu yang tepat untuk anaknya menyikat gigi setelah makan makanan yang kariogenik. ......Dental caries is one disease the teeth and mouth that many experienced particularly by primary school children. The incidence of dental caries in children is measured through an DMFT index. Dental caries is closely related to elementary school children in the habit cariogenic foods consumption. In Serang City, the number of students who suffer from dental caries highest in the Puskesmas Taktakan working area. This study purpose was to determine the relationship students characteristics and cariogenic food consumption behavior with dental caries incidence at students aged 11-12 years Selected the State Elementary School At The Puskesmas Taktakan working area Serang city 2015 include characteristics (gender, pocket money, knowladge, attitude, salivary pH), student behavior (cariogenic food consumption, tooth brushing habits, tooth brushing method). The method used in this study is using Cross Sectional design. Research conducted at Selected The State Elementary Schools located in the Puskesmas Taktakan working area serang city using cluster random sampling techniques that is Drangong I State Elementary School, Taktakan I State Elementary School and Pereng State Elementary School Calculation results of the samples Size about 140 people. Data collection using questionnaires, examination of teeth, salivary pH measurement and correct brushing method. Data was analyzed using univariate analysis, Bivariate with Chi Square Test and multivariate with Regresi Logistic test. DMFT index recapitulation that frequency is the highest DMFT on Drangong And Pereng I State Elementary School and Pereng State Elementary School while Taktakan I State Elementary School including the severity of dental caries low Cariogenic foods most frequently consumed foods kariogeniknya students is high and sweet sticky solid. That have a significant relationship with the dental caries incidence by p value < 0,05 is pocket money, knowladge, attitude, cariogenic food consumption, tooth brushing habits, tooth brushing method and whereas variables that do not have a significant relationship with the dental caries p value > 0,05 is incidence is gender, salivary pH. The most dominant factor is cariogenic food consumption variable associated with the dental caries incidence. While the confounding variable is the tooth brushing habits variable, tooth brushing method variable. Suggestion for students can bring food that is not too sweet and sticky, Routine dental examinations on all student Puskesmas Taktakan cooperate with the school to provide counseling to parents about their dental health, especially regarding the right time to brush her teeth after eating cariogenic foods.

Abstrak :
Sebagian besar manusia tidak bersahabat dengan lingkungan. Mereka bersikap dan bertindak secara tidak etis terhadap alam semesta. Alam dieksploitasi tanpa batas. Masalah dalam riset ini adalah terjadi eksploitasi lingkungan yang masif sehingga dibutuhkan pendekatan edukasi tentang lingkungan. Tujuan akhir riset adalah memahami cara pandang dan mendapatkan ide-ide baru dalam penanaman kesadaran lingkungan. Komunitas Eco Camp dipilih menjadi lokasi riset karena komunitas Eco Camp memiliki keunikan dalam penanaman kesadaran ekologis dengan melibatkan sisi refleksi filosofis dan meditatif, serta penanaman tujuh kesadaran baru hidup ekologis. Metode riset menggunakan metode analisis deskriptif dan pendekatan appreciative inquiry. Hasil riset ini menunjukkan penanaman kesadaran ekologis dengan menerapkan unsur refleksi filosofis, meditatif, dan pembiasaan melalui tujuh kesadaran baru ekologis membawa dampak perubahan perilaku terhadap lingkungan. Kesimpulan riset adalah penanaman kesadaran lingkungan dan pembiasaan dengan menyentuh sisi refleksi filosofis membawa pengaruh yang positif terhadap kesadaran ekologis. ......Most humans are not friendly with the environtment. They behave and act unethically towards the nature. The nature is exploited without limits. The problem in this research is that there is massive exploitation of the environment so that an educational approach to the environment is needed. The last of goal of the research is to understand the perspectives and get new ideas in implanting environtmental awareness. The Eco Camp community is chosen as the research location because the Eco Camp community has unique value in impelementing ecological awareness by involving a philosophical reflective side, as wel as seven new awareness of ecological life. The research method uses a descriptive analysis method and appreciative inquiry approach. The results of this research show that in implementing ecological awareness by applying philosophical reflective elements and habituation through seven new ecological awareness bring behavior change impact towards the environment. The conclusion of the research is the the implementation of environment awareness and habituation by touching the rflective side of philosophy bring positive influence toward ecological awareness.

Abstrak :
Pendahuluan MicroRNA (miR)-544a telah diidentifikasi sebagai pengatur potensial dalam jalur WNT/β-Catenin, namun perannya yang spesifik pada kanker paru-paru non-sel kecil (KPKBSK) dan hubungannya dengan resistensi kemoterapi berbasis platinum masih belum jelas. Oleh karena itu, kami bertujuan untuk menentukan hubungan antara ekspresi miR-544a dan GSK-3β, β-catenin, dan CD44 dengan resistensi kemoterapi berbasis platinum pada pasien KPKBSK stadium lanjut. Metode Penelitian ini dirancang sebagai studi kasus kontrol di mana individu yang didiagnosis dengan KPKBSK stadium lanjut (III-IV) dari Januari 2018 hingga Juli 2023 dari 6 rumah sakit berbeda di Indonesia. Analisis tingkat miR-544a dilakukan menggunakan Kit PCR QuantiTect SYBR Green secara real-time. Ekspresi GSK, β-catenin, dan CD44 menggunakan pewarnaan imunohistokimia (IHK) dilakukan dari formalin-fixed paraffin embedded (FFPE). Evaluasi intensitas IHK dibagi menjadi empat kategori ekspresi: negatif atau tidak berwarna, positif lemah, positif sedang, dan positif kuat. Dari 500 sel, kami menggunakan rumus semi-kuantitatif H-score. Hasil Studi ini melibatkan 62 pasien KPKBSK stadium lanjut yang menjalani kemoterapi berbasis platinum dan menemukan miR-544a lebih tinggi pada responden yang buruk, dengan nilai p yang signifikan sebesar 0,009. Model prediktif untuk miR-544a menunjukkan nilai Roctab sebesar 0,6957. Nilai batas miR-544a sebesar 2,08 menghasilkan sensitivitas 64% dan spesifisitas 67,57%. Tingkat miR-544a di atas 2,08 secara signifikan terkait dengan respons pengobatan yang lebih buruk (OR 2,159, 95% CI 1,132 - 4,117, p = 0,016). Kesimpulan Studi ini menunjukkan bahwa tingkat miR-544a merupakan biomarker yang signifikan untuk memprediksi respons kemoterapi pada pasien dengan KPKBSK stadium lanjut. ......Introduction MicroRNAs (miR)-544a has been identified as a potential regulator in the Wnt/β-Catenin pathway, but its specific role in non-small cell lung cancer (NSCLC) and its relationship with platinum-based chemotherapy resistance, remains unclear. Thus, we aim to determine the relationship between the expression of miR-544a and GSK-3β, β-catenin, and CD44 with platinum-based chemotherapy resistance in advanced stage NSCLC patients. Methods The research is designed as a case control study in which individuals diagnosed with advanced stage (III-IV) NSCLC from January 2018 and July 2023 from 6 different hospitals in Indonesia. The analysis of miR-544a levels was done using the real-time QuantiTect SYBR Green PCR Master Kit. The expression of GSK, β-catenin, and CD44 expression using immunohistochemistry (IHC) staining was performed from the formalin-fixed paraffin embedded (FFPE). The evaluation of IHC intensity was divided into four expression categories: negative or unstained, weakly positive, moderately positive, and strongly positive. From 500 cells, we used the semi-quantitative H-score formula. Results This study of 62 advance NSCLC patients undergoing platinum-based chemotherapy and found miR-544a were higher in poor responders, with a significant p-value of 0.009. The predictive model for MiR-544a demonstrated a Roctab value of 0.6957. A miR-544a cutoff value of 2.08 yielded sensitivity of 64% and specificity of 67.57%. MiR-544a levels above 2.08 were significantly associated with poorer treatment response (OR 2.159, 95% CI 1.132 - 4.117, p = 0.016). Conclusions The study demonstrates that miR-544a levels are a significant biomarker for predicting chemotherapy response in patients with advance NSCLC.