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"Latar belakang. Berat badan lebih dan obesitas sebagai masalah kesehatan juga ditemukan di Indonesia. Obesitas berkaitan dengan sindrom metabolik, yang juga dapat ditemukan pada populasi dengan berat badan normal.Tujuan. Untuk melihat perbedaan proporsi sindrom metabolik (menurut kriteria NCEP-ATP III, dan modifikasi Asia Pasifik) pada populasi wanita obes (IMT > 25 kglm2 ) dan non-obes (IMT 18,5 - 24,9 kglm2), serta profil komponen sindrom metabolik.Metode. Penelitian bersifat deskriptif analitik, dilakukan pada bulan Desember 2003 - Juni 2005, di Pali Lipid dan Obesitas, Divisi Metabolik Endokrinologi RSCM. Subyek ialah perawat wanita di RSCM, berusia 20 hingga 50 tahun. Jumlah responden ialah 45 subyek obes, dan 45 non-obes.Hasil. Dari 90 responden total, 12 (26,7 %) subyek obes memenuhi kriteria sindrom metabolik menurut NCEP-ATP III. Menggunakan kriteria modifikasi Asia Pasifik, didapatkan 14 (31,1 %) subyek obes mengalami sindrom metabolik. Tidak ada subyek non-obes yang memenuhi kriteria sindrom metabolik [p < 0,0011 Tiga puluh (66,7 %) subyek obes mempunyai lingkar pinggang > 88 cm, dibandingkan 0 (0,0 %) subyek non-obes. Empat (8,9 %) subyek obes mempunyai tekanan darah 130185 mmHg, pada kelompok non-obes hanya 1 (2,2 %) subyek. Tiga (6,7 %) subyek obes memiliki kadar glukosa darah puasa a. 110 mg/dL atau merupakan pasien DM tipe 2 yang mendapat obat hipoglikemik oral, sedangkan pada kelompok non-obes tidak ada_ Tigabelas (28,9 %) subyek obes mempunyai kadar trigliserida 150 mgIdL, dan tidak ada pada kelompok non-obes. Kadar kolesterol HDL < 50 mg/dL didapatkan pada 26 (57,8 %) subyek obes, dan 9 (20,0 %) pada subyek non-obes.Simpulan. Sindrom metabolik hanya ditemukan pada populasi perawat wanita obes.

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Backgrounds. Overweight and obesity as health problems are also found in Indonesia. Obesity is related to metabolic syndrome, which can also occurs in normal weight population.

Objectives. To look at the difference in metabolic syndrome (according to NCEPATP III criteria, and modified Asia Pacific criteria) proportion within obese female population (BMI > 25 kg/m2 ) and non-obese female population (BMI 18,5 -- 24,9 kg/m2), and the profile of metabolic syndrome components.

Methods. This cross sectional study was conducted from December 2003 to June 2005, at Lipid and Obesity Clinic, Metabolic and Endocrinology Division, Department of Internal Medicine, University of Indonesia - Cipto Mangunkusumo General Hospital. Subjects were Cipto Mangunkusumo General Hospital female nurses, ages 20 to 50 years old. The first group consisted of 45 obese subjects, and the second group of 45 non-obese persons.

Results. Twelve (26.7 %) of obese subjects fulfilled the NCEP-ATP III criteria for metabolic syndrome. Using the modified Asia Pacific criteria, there were 14 (31.1 %). None of the non-obese subjects fulfilled any of those two criteria [p < 0.001]. Thirty (66.7 %) of obese subjects had waist circumference > 88 cm, as compared to none of non-obese subjects. Four (8.9 %) of the obese subjects had blood pressure

130185 mmHg, as compared to only 1 (2.2 %) in non-obese subjects. Only 3 (6.7 %) of the obese subjects had fasting glucose levels > 110 mg/dL or had been diagnosed as DM type 2 patient and receiving oral hypoglycemic drug, whereas none of the non-obese subjects. Thirteen (28.9 %) of the obese subjects had triglyceride level > 150 mg/dL, and none of non-obese subjects. HDL-cholesterol level < 50 mg/dL was found in 26 (57.8 %) of obese subjects, and 9 (20.0 %) of non-obese subjects.

Conclusions. Metabolic syndrome was found only in obese female nurses."

"Hepatitis pasca transfusi (HPT) telah lama mendapat perhatian para ahli. Sampai saat ini masih tetap merupakan salah satu komplikasi tindakan transfusi yang sering terjadi dan sering berkembang menjadi kronis, walaupun telah dilakukan pemilahan HBsAg terhadap semua darah donor oleh PMI (1,2,3 ). Berbagai penelitian mengenai kekerapan hepatitis pasca transfusi pada penderita yang mendapat transfusi darah dan komponen-komponennya menunjukkan angka yang berbeda-beda. Angka kekerapan HPT di Amerika Serikat berkisar antara 10-20%, di - Eropa Utara berkisar antara 2-4% sedangkan di Eropa Selatan mungkin berkisar antara 15-20% (dikutip dari 4). Di Jakarta, Rahman (1988) pada penelitiannya terhadap 60 penderita dengan tindakan bedah yang mendapat transfusi darah melaporkan terjadinya 18 kasus (30%) hepatitis pasca transfusi, 3 diantaranya hepatitis virus B (5). Sedangkan Sutanto (1989) pada penelitiannya terhadap 80 penderita yang mendapatkan transfusi darah melaporkan terjadinya 13 kasus hepatitis pasca transfusi (16,25%), 1 diantaranya adalah hepatitis virus B (6). Pada kedua penelitian tersebut, penyebab hepatitis pasca transfusi belum dapat dideteksi, sehingga disebut hepatitis Non A Non B (5,6).

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Post-transfusion hepatitis (HPT) has long received the attention of experts. Until now, it is still a frequent complication of transfusion procedures and often develops into a chronic one, even though HBsAg has been screened for all donor blood by PMI (1,2,3). Various studies regarding the frequency of post-transfusion hepatitis in patients who received blood transfusions and its components show varying figures. The frequency of HPT in the United States ranges from 10-20%, in Northern Europe it ranges from 2-4%, while in Southern Europe it may range from 15-20% (quoted from 4). In Jakarta, Rahman (1988) in his research on 60 patients with surgical procedures who received blood transfusions reported the occurrence of 18 cases (30%) of post-transfusion hepatitis, 3 of which were viral hepatitis B (5). Meanwhile, Sutanto (1989), in his research on 80 patients who received blood transfusions, reported 13 cases of post-transfusion hepatitis (16.25%), 1 of which was hepatitis B virus (6). In both studies, the cause of post-transfusion hepatitis could not be detected, so it was called Non A Non B hepatitis (5,6).

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