Hasil Pencarian  ::  Simpan CSV :: Kembali

Abstrak :
Latar Belakang: Sel endotel kornea (SEK) paling mudah mengalami kerusakan pasca fakoemulsifikasi (fako). Pengaturan parameter fako menjadi salah satu cara untuk mengurangi kerusakan SEK. Tekanan intaokular (TIO) selama fako berlangsung mempengaruhi kenyamanan pasien. TIO dipengaruhi oleh pengaturan parameter fako. Tujuan: Membandingkan pengaturan fako dengan parameter high (H) dan low (L) di Rumah Sakit Cipto Mangunkusumo (RSCM) terhadap SEK dan persepsi nyeri pasien selama fako. Desain: Uji klinis randomisasi tersamar ganda. Hasil: 48 sampel untuk kedua kelompok fako parameter high dan low terkumpul selama periode November 2013-April 2014. Penilaian objektif SEK meliputi endothel cell density (ECD) dan central corneal thickness (CCT). Persepsi nyeri untuk menilai persepsi nyeri pasien digunakan kartu visual analog scale (VAS) yang telah menjadi standar JCI di RSCM. Terjadi peningkatan CCT dan penurunan ECD kedua kelompok parameter pasca fako 1 bulan, masing-masing 0.23VS2.23 dan 8.53VS6.99 (p>0.05). Tidak ada perbedaan signifikan pada VAS kedua parameter. Efikasi fako berdasarkan penilaian cumulative dissipated energy (CDE) kelompok H lebih baik daripada L (15.80VS21.29). Kesimpulan: Tidak ada perbedaan keamanan dan kenyamanan pasien fako parameter H dan L. ......Background: Corneal endothelial cell (CEC) prone to damage after phacoemulsification (phaco). Phaco parameter setting is an effort to reduce damage to the CEC. Patient?s comfort during phaco is influenced by IOP during phaco, in which are influenced by parameter settings. Purpose: To compare phaco setting parameters from high (H) and low (L) parameters in Cipto Mangunkusumo (CM) hospitals impacted on CEC and patient?s pain perception (PP) during phaco procedure. Study design: randomized control trial double blind. Results: 48 outpatients were elegibly selected by RCT at CM hospital in periods of November 2013 ? April 2014. Impact of setting parameter difference were observed by objective measurement of endothel cell density (ECD), central corneal thickness (CCT). For PP a JCI approved standard using visual analog scale (VAS) were adapted. A built in software for phaco US energy count which is cumulative dissipated energy (CDE) used to objectively timed the phaco time, duration of operation (DO) were timed, and standard visual acuity (VA) was also noted. Analisis data using general linear model (GLM) repeated measures. Increase of CCT and decrease of ECD after 1 month in high and low phaco parameter are not significantly difference, respectively 0.23VS2.23 and 8.53VS6.99 (p>0.05).Significant difference were found in CDE between H and L; 15.80VS21.29 (p0.015).No statisticaly significant difference of VAS nor DO and VA. Conslusion: No different in safety and patient's comfort using high and low parameter phaco.

Abstrak :
ABSTRAK
Tesis ini bertujuan untuk mengetahui efektivitas dan keamanan pada pemberian midriatika injeksi epinefrin intrastroma kornea dengan intrakamera pada vitrektomi pars plana. Sebelum vitrektomi dilakukan pengukuran diameter pupil serta diameter pupil optimal yang diperoleh. Ketebalan sentral dan densitas kornea diukur menggunakan spekular mikroskop Non Conrobo Konan sebelum vitrektomi, saat follow-up 1 hari dan 1 minggu paska vitrektomi. Perbedaan bermakna p=0.015 untuk delta perubahan diameter pupil kelompok injeksi epinefrin intrastroma dibandingkan kelompok intrakamera. Rerata mean pada injeksi epinefrin intrakamera terhadap Central Corneal Thickness CCT awal, 1 hari dan 1 minggu terdapat perbedaan bermakna p = 0.041. Delta diameter pupil pada pemberian injeksi epinefrin intrastroma lebih lebar dibandingkan dengan intrakamera pada vitrektomi pars plana. Ketebalan CCT 1 minggu setelah tindakan pada injeksi epinefrin intrastroma kornea lebih rendah dibandingkan dengan intrakamera.

---

ABSTRACT
This thesis is to determine the effectiveness and safety of intrastromal epinephrine injection with intracameral injection on pars plana vitrectomy. The measurement of pupil diameter was done before vitrectomy and optimal pupil diameter is obtained. Central corneal thickness CCT and Endothelial Cell Density ECD were measured using a specular microscope Non Conrobo Konan before vitrectomy, at follow up 1 day and 1 week after vitrectomy. Optimal pupil diameter no significant difference p 0.05 . The difference was significant p 0.015 for the delta changes in pupil diameter intrastromal epinephrine injection group compared to the group intracameral. Average mean in epinephrine injection group intrakamera the initial CCT, 1 day and 1 week there is a significant difference p 0.041. Delta pupil diameter in epinephrine injection intrastromal wider than intracameral injection. CCT thickness 1 week after the epinephrine corneal intrastromal injection is lower than intracameral injection.

Abstrak :
Penelitian ini bertujuan untuk mengevaluasi kualitas air mata dan perubahan densitas sel goblet dengan penggunaan lensa kontak silikon hidrogel lotrafilcon B pada penggunaan daily wear dan extended wear 6 malam berturut-turut. Penelitian ini merupakan uji klinis intervensi randomisasi tersamar tunggal. Sebanyak lima puluh enam subyek yang telah di randomisasi dibagi menjadi dua kelompok n = 28 di masing-masing kelompok. Kedua kelompok memakai lensa kontak hidrogel silikon Lotrafilcon B secara daily wear vs extended wear. Parameter klinis Non-Invasif Break Up Time NIBUT, densitas sel goblet PAS, Interblink Interval IBI dan Ocular Protection Index OPI. Terdapat perbedaan NIBUT dan densitas sel goblet bermakna pada minggu ke 4 antara dua kelompok p 0,015 dan p.

---

The purpose of this study is to evaluate tear film quality and goblet cell density changes with the use of soft contact lenses of silicone hydrogel lotrafilcon B on daily wear and extended wear in 1 month. This is single blind randomized clinical trial. A total of fifty six subjects who had been consecutively randomized were divided into two groups n 28 in each. Both groups were wearing silicone hydrogel contact lenses Lotrafilcon B, the first group used daily wear and the second group used extended wear 6 consecutive nights. The clininal evaluation of the eyes in each group were performed on pre fitting, 1st week and 4th week after contact lens fitting. The clinical parameter were Non Invasive Break Up Time NIBUT using Tearscope PlusTM, goblet cell density using conjunctival impression cytologies CIC with Periodic Acid Schiff PAS Staining, Interblink Interval IBI and Ocular Protection Index OPI. In this study obtained more female sex subjects than men with a ratio of 3.6 1. There was a significant mean NIBUT difference at week 4 between two groups p 0,015. There was a decrease in goblet cell density in both groups with significant differences p.