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"Tujuan umum penelitian ini adalah mendapatkan suatu metode deteksi dini kanker berdasarkan analisis sifat optik antara jaringan normal dan adenokarsinoma menggunakan metode autofluoresensi multieksitasi. Pengamatan sifat autofluoresensi jaringan dilakukan pada sampel biopsi seksi jaringan adenokarsinoma, sampel mencit GR yang ditransplantasi adenokarsinoma, dan kultur sel SM 1. Eksitasi jaringan dilakukan menggunakan lampu Light Emiting Diode (LED) pada beberapa kisaran panjang gelombang cahaya tampak. Pada penelitian ini diperoleh data bahwa nilai intensitas autofluorsensi (IAF) pada kisaran panjang gelombang merah dari sel dan jaringan adenokarsinoma cenderung lebih rendah dibandingkan dengan jaringan normal jika dieksitasi oleh LED biru. Sebaliknya nilai IAF pada panjang gelombang infra merah dari sel dan jaringan karsinoma cenderung lebih tinggi dibandingkan dengan jaringan normal apabila dieksitasi oleh LED merah.

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Characterization of Adenocarcinoma?s Autofluorescence Properties Using Multiexcitation Analysis Method. General purpose of this research is to get an early cancer detection method based on the properties of optical analysis between normal and adenocarsinoma tissue using the multiexcitation autofluorescence method. Observation of autofluorescence properties was done on the biopsy sample of adenocarcinoma tissues, GR mice transplanted by adenocarsinoma, and cell culture SM 1. Excitation on tissue was done by using the lamp Light Emitting Diode (LED) at some visible light wavelength range. This research obtained that the value of Intensity Auto fluorescence (IAF) at range red wavelength of cells and adenocarsinoma tissues tend to lower compared to the cells normal tissues if its were excited by blue LED. On the contrary, the value of IAF at infra red wavelength from cells and carcinoma tissues tend to higher compared to the cells and normal tissues if its were excited by red LED."

"This is a study on carotenoid extracted from ?Minyak Buah Merah? (Pandanus conoideus) in therapy simulation using high dose of β-carotene on two lymphocytes?that of a healthy subject and a leukemia patient. Superoxide production in mithocondrial lymphocyte as a result of β-carotene exposure was examined using a flow cytometer. The test finds that superoxide (a specific mitochondrial free radical) increases easier and faster in leukemic lymphocytes than in normal lymphocytes. The results of the study support previous meta-analysis studies that high dosages of β-carotene and vitamin E supplements as antioxidant should be discouraged because it increases all-cause mortality."

"The studies of neuro-protection and neuro-therapy effects of Acalypha indica Linn. water extract ex vivo on Musculus gastrocnemius frog have already done at three Departments in Faculty of Medicine, University of Indonesia. The experimental studies were done on 2 groups of frog for neuro-protection and neuro-therapy effects. Each group of frog was divided into 7 subgroups of application, 4 samples each. There were 5 subgroups of doses: 5; 10; 15; 20; 25 mg and 2 subgroups as control. Pancuronium bromide 0.2%, 4 mg, was used for a positive control as muscle relaxant. Neuroprotection study was done as follow: ringer - extract - pancuronium bromide, and neuro-therapy study was ringer - pancuronium bromide - extract, respectively. The parameters measured in these studies were the electrical activities such as amount and duration (second) of re-polarization; depolarization, resting potential, and the height of spike after electrical stimulation at 5 mV. Neuro-protection effect of extract was determined by the ability of muscle to show the electrical response after incubating with pancuronium bromide for 10 minutes, and after incubating with extract for 10 minutes for neuro-therapy effect. In the dose of 15 mg and 20 mg/mL of A. indica Linn. extract showed better activities than the dose of 25 mg of extract, both as neuro-protection and neuro-therapy effects, but statistically its have not a significant difference. This study should be followed by an in vivo experiment on frog and it would be done in pharmacokinetic and pharmacodynamic studies on other animal models."