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Abstrak :
As an essential nutrient, zinc play important roles in many biological functions. The activity of zinc as co-factor enzymes is supporting by the activity of copper and iron. The study was observed the changes of level activity of zinc, copper and iron concentration in sub lingual gland saliva, sub mandible gland saliva and parotids gland saliva The concentration of zinc, copper and iron were determinant by using the X-Ray Fluorescent. The concentration of zinc and iron were significantly increase (p<0.005) in sub lingual within 60 min restraint stress, and copper was significantly decrease (p

Abstrak :
Proses penuaan mengakibatkan perubahan fisiologis yang terkait dengan masalah kesehatan pada orang usia lanjut (usila). Penyakit degeneratif merupakan faktor risiko terjadinya gangguan kognitif pada orang usila. Terbentuknya akumulasi amyloid β (Aβ) merupakan hal utama terjadinya gangguan kognitif. Mineral seng memiliki peran penting sebagai antioksidan dan proses akumulasi Aβ. Penelitian ini dilakukan dengan desain potong lintang pada 58 orang usila di Kelurahan Kartini yang dilaksanakan pada bulan Januari 2019 untuk mengetahui korelasi kadar seng rambut dengan fungsi kognitif pada populasi usila. Pemeriksaan kadar seng rambut dengan inductively coupled plasma spectrometer (ICPS) dan fungsi kognitif dinilai dengan instrumen abbreviated mental test (AMT). Data dianalisis dengan menggunakan uji korelasi. Rerata usia subjek 65,4 ± 4,4 tahun. Nilai median asupan seng sebesar 5,65 (3,2-13,3) mg/hari. Rerata kadar seng rambut sebesar 123,23 ± 69,71 µg/gram rambut. Sebagian besar memiliki fungsi kognitif normal (91,4%). Hasil penelitian ini menunjukkan bahwa tidak terdapat korelasi asupan seng dengan kadar seng rambut (p=0,349 ; r= -0,125) serta tidak ditemukan adanya korelasi kadar seng rambut dengan fungsi kognitif pada populasi usila (p=0,871 ; r= -0,022). Kesimpulan penelitian ini adalah tidak terdapat korelasi antara kadar seng rambut dengan fungsi kognitif pada populasi usila. ......Aging process cause physiological changes related to health problems in elderly. Degenerative diseases are the risk factor for cognitive impairment in elderly. Amyloid β (Aβ) accumulation is the major cause of cognitive impairment. Zinc has an important role in antioxidant and Aβ accumulation process. A cross sectional study of 58 elderly subjects was done at Kartini Regency in January 2019 to evaluate the correlation between hair zinc level and cognitive function in elderly population. Hair zinc level was measured by inductively coupled plasma spectrometer (ICPS) and cognitive function assessed by abbreviated mental test (AMT). Data analysis was done by correlation test. The mean age was 65.4 ± 4.4 years. The median value of zinc intake was 5.65 (3.2 - 13.3) mg/day. The mean hair zinc level was 123.23 ± 69.71 µg/gram hairs. Almost all subjects had normal cognitive function (91.4%). The results of this study indicate that there was no correlation between zinc intake and hair zinc level (p=0.349 ; r= -0.125) and there was no correlation between hair zinc level and cognitive function in elderly population (p=0.871 ; r= -0.022). In conclusion, there was no correlation hair zinc level and cognitive function in elderly population.

Abstrak :
ABSTRAK

Latar Belakang: Kehamilan merupakan suatu proses yang membutuhkan asupan seng yang adekuat guna menunjang kesehatan ibu dan janin. Defisiensi seng akibat kurangnya asupan dan bioavailabilitas seng dalam diet masih merupakan masalah di negara berkembang termasuk Indonesia.

Tujuan: Tujuan dari penelitian ini adalah untuk melihat kadar seng serum dan hubungannya dengan asupan makanan dalam upaya perbaikan asupan seng pada kehamilan trimester tiga.

Desain: Penelitian dilakukan terhadap 51 subjek ibu hamil trimester tiga dengan menggunakan desain studi potong lintang dan consecutive sampling.

Hasil: Dari penelitian diperoleh hasil rerata kadar seng serum pada subjek penelitian adalah 39,32±6,28 µg/dl dengan frekuensi seng serum rendah dari normal sebesar 92,16%. Semua subjek penelitian tidak memenuhi asupan seng, serat, energi dan protein sesuai AKG. Asupan besi subjek penelitian melebihi AKG pada 96,1% subjek dan semua subjek memiliki rasio molar fitat lebih dari 15. Terdapat korelasi lemah yang tidak bermakna secara statistik antara asupan seng (r=0.068), besi (r=0,09), fitat (r=0,081), serat (r=0,026), energi (r=0,073) dan protein (r=0,033) dengan seng serum subjek penelitian.

Kesimpulan: Kesimpulan dari penelitian ini adalah tidak terdapat hubungan antara asupan seng, besi, fitat, serat, energi dan protein dengan seng serum subjek penelitian. Dibutuhkan edukasi tentang bahan makanan sumber yang baik untuk memperbaiki asupan seng, besi, fitat, serat, energi dan protein pada ibu hamil.

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ABSTRAK

Background: Pregnancy is a process that requires an adequate zinc intake to support maternal and perinatal health. However, zinc deficiency due to inadequate intake and zinc bioavailability in diet still remain a problem in developing countries, including Indonesia.

Objective: The aim of this study is to investigate serum zinc levels and its relation to food intake in order to improve zinc intake in late pregnancy.

Design: The method used in this study was cross sectional, consecutive sampling on 51 late pregnancy subjects.

Results: The study results mean serum zinc level was 39.32±6.28 µg/dl with prevalence of serum zinc below normal 92.16%. All of the subjects did not meet the RDI of zinc, fiber, energy and protein. As 96.1% subjects meet the RDI of iron and all subjects had phytate-zinc molar ratio more than 15. There was a weak correlation that not statistically significant between the intake of zinc (r=0.068), iron (r=0.09), phytate (r=0.081), dietary fiber (r=0.026), energy (r=0.073) and protein (r=0.033) with serum zinc.

Conclusion:This study conclude that there was no association between intake of zinc, iron, phytate, dietary fiber, energy and protein with serum zinc level in late pregnancy. Pregnant women need a nutritional education about good food source to improve zinc, iron, dietary fiber, energy, and protein intakes.

Abstrak :
Penelitian ini merupakan penelitian potong lintang yang bertujuan mengetahui korelasi antara kadar seng serum dengan aktivitas SOD eritrosit pada pasien geriatri non-frail dan frail di Poliklinik Geriatri RSUPN Cipto Mangunkusumo Jakarta pada pertengahan bulan Agustus 2014 sampai pertengahan bulan September 2014. Subjek didapatkan secara consecutive sampling, sebanyak 60 orang (30 orang untuk masing-masing kelompok non-frail dan frail) yang memenuhi kriteria penelitian dan mengikuti penelitian sampai selesai. Tidak didapatkan korelasi signifikan antara kadar seng serum dengan aktivitas SOD eritrosit subjek penelitian, baik secara keseluruhan maupun per kelompok. ......This cross-sectional study aimed to know the correlation between serum zinc level and the erythrocyte SOD activity both in non-frail and frail geriatric patients. These subjects were collected from mid-August 2014 to mid-September 2014 from the clinic of Geriatric, Cipto Mangunkusumo General Hospital. Through conducting a consecutive sampling, 60 subjects who met the study criteria and completed all study progress, that consisted 30 persons who represent each non- frail and frail group, were enrolled into this study. Serum zinc level did not show significant correlation with erythrocyte SOD activity, both overall and per group.