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"Penyakit tuberkulosis (TB) adalah penyakit menular yang disebabkan oleh Mycobacterium tuberculosis dan merupakan penyakit menular yang masih menjadi masalah kesehatan di masyarakat. Jumlah penderita TB pam BTA positif di Kabupaten Subang Tahun 2006 sebanyak 1.095 kasus (Insidens rate 107/100.000 penduduk). Di Kabupaten Subang selama lima tahun terakhir sampai tahun 2006 angka penemuan penderita baru TB paru BTA positif dan angka penemuan penderita seluruh tipe meningkat, keadaan itu menunjukkan bahwa penyakit TB masih menjadi masalah kesehatan di masyarakat. Program Penanggulangan Tuberkulosis di Kabupaten Subang untuk pengumpulan data menggunakan sistem jemput bola pada saat petugas kabupaten melakukan supervisi. Sistem ini mengakibatkan data yang terkumpal pada akhir triwulan tidak sama dengan angka yang sebenarnya ada di puskesmas apabila supervisi dilakukan pada awal atau pertengahan triwulan. Pengembangan sistem yang dilakukan berdasarkan metode System Development Lye Cycle, yaitu planning analysis system, design, implementation, maintenance dan evaluation system dengan memadukan konsep Data Base Management System dan terintegrasi dengan data spasial sehingga menambah keunggulan dalam Sistem Informasi P2TB berbasis wilayah (SIG) di Kabupaten Subang. Hasil analisis sistem dapat mengidentifikasi permasalahan manajemen sistem informasi penanggulangan penyakit TB serta alternatif solusi pada tahap input, proses dan output. SIP2TB berbasis wilayah dirancang untuk kemudahan input data dan otomasi proses pengolahannya menjadi informasi. Output yang dihasilkan berupa laporan reguler, tabulasi indikator program, grafik indikator program dan informasi pemetaan endemisitas wilayah dengan unit pengamatan terkecil desa. Interpretasi epidemiologis kasus TB pada visual peta ini dapat mengetahui jangkauan pelayanan kesehatan (Puskesmas) dalam penanggulangan TB dan kepadatan penduduk dengan sebaran kasus TB. Aplikasi SIP2TB ini dapat menjadi alat manejemen dalam program penanggulangan TB, menguatkan kemampuan pada kegiatan monitoring dan evaluasi. Output yang dihasilkan dapat dijadikan informasi untuk masukan pada pengambil keputusan dalam program Penanggulangan TB. SIP2TB ini diharapkan dapat dijadikan alat bagi pengelola program dan bila memungkinkan dapat dikembangkan di puskesmas serta menjadi model bagi kabupaten lain.

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Tuberculosis (TB) is a communicable disease caused by Mycobacterium tuberculosis that it is still beeing a public health problem in the community. Number of detected new smear positive pulmonary TB were 1,095 cases in Subang district by the year 2006 referred to the national incidence rate, 107/100,000. Over the last five year there were an increased number of detected all type TB cases in Subang district. This showed that TB still becomes a public health problem in the community.

TB Control Program in Subang has been carrying out ball pick up for TB data colection in district level. It means that district TB supervisor (wasor) goes to health services unit to pick up data or registry when quarterly supervisory visit. This system might cause the data differences between the real existing data at health service unit (UPK) and collected data by wasor at the same period of time the wasor visit UPK at the begining or in the middle ofthe quarter.

System Development was done on the basis of System Development Life Cycle method, including planning analysis system, design, implementation, maintenance and evaluation system. Through combining the concept of Dafa Base Management System and integrated with spatial data able to increased an advances of TB Control Program Geographical Information System in Subang district. Result system analysis was able to identify the management information system of TB control program as well as alternative solution on input phase, process phase and output phase.

The GISTB was designed to make input data and data processing to be information becoming easier. The output is a regular report, tables, graphs of the program indicators as well as information mapping of TB case distribution in village level as an investigation unit. Epidemilogy Interpretation of TB case on the visual map shows the level of health center coverage in relation to TB services. It also shows the population density and case distribution.

The GISTB application will be able become as a management tool of TB control program for strengthening monitoring and evaluation system. Therefore a decision making for TB control program in Subang based on valid, acurate and reliable data as an output ofthe system. This system also is expected to be able to be adopted as a wasor tools and expanded to health service unit level as well as being a model in other districts."

"ABSTRAKPenyakit tuberkulosis paru masih merupakan masalah kesehatan masyarakat yang cukup besar. Salah satu faktor yang menunjang keberhasilan pemberantasan adalah pendidikan kesehatan. Beberapa media pendidikan tentang tuberkulosis setelah dibuat, akan tetapi media tersebut selalu memerlukan penyempurnaan.Penelitian ini bertujuan untuk mengetahui apakah bookletAku Tekun Aku Sembuh dapat meningkatkan pengetahuan penderita tuberkulosis paru di Rumah Sakit Dr. Soetomo Surabaya.Penelitian menggunakan "Studi intervensi" dengan desain "Randomized pretest postest with control group". Data yang didapat dianalisa dengan Student t test.Hasil penelitian menunjukkan ada perbedaan bermakna antara nilai uji awal aan uji akhir pada kelompok Studi (p <0,05) dan tak ada perbedaan bermakna antara nilai uji awal dan uji akhir pada kelompok kontrol (p > 0,05). Sehingga dapat disimpulkan bahwa booklet "Aku Tekun Aku Sembuh dapat meningkatkan pengetahuan penderita tuberkulosis paru di Rumah Sakit Dr. Soetomo Surabaya. Akan tetapi dari penilaian uji awal nampak bahwa pengetahuan responden tentang penyakitnya masih belum memadai.Berdasarkan hasil tersebut penulis mengajukan saran agar pendidikan kesehatan pada penderita TB Paru ditingkatkan antara lain dengan menyebarkan booklet tersebut kepada sasaran yang tepat.

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"Penyakit tuberkulosis (TB) adalah penyakit menular yang disebabkan oleh Mycobacterium tuberculosis dan merupakan penyakit menular yang masih menjadi masalah kesehatan di masyarakat. jumlah penderita TB paru BTA positif di Kabupaten Subang Tahun 2006 sebanyak 1.095 kasus (Insidene rate 107/100.000 penduduk). Di Kabupaten Subang selama lima tahun terakhir sampai tahun 2006 angka penemuan penderita baru. TB paru BTA positif dan angka penemuan penderita seluruh tipe meningkat, keadaan itu menunjukkan bahwa penyakit TB masih menjadi masalah kesehatan di masyarakat. Program Penanggulangan Tuberkulosis di Kabupaten Subang untuk pengumpulan data menggunakan sistem jemput bola pada saat petugas kabupaten melakukan supervisi. Sistem ini mengakibatkan data yang terkumpul pada akhir triwulan tidak sama dengan angka yang sebenarnya ada di puskesmas apabila supervisi dilakukan pada awal atau pertengahan triwulan. Pengembangan sistem yang dilakukan berdasarkan metode System Development Life Cycle, yaitu planning analysis system, design, implementation, maintenance dan evaluation system dengan memadukan konsep Data Base Management System dan terintegrasi dengan data spasial sehingga menambah keunggulan dalarn Sistem Informasi P2TB berbasis wilayah (SIG) di 1Cabupaten Subang. Hasil. analisis system dapat mengidentifikasi permasalahan manajemen sistem informasi penanggulangan penyakit TB serta altematif solusi pada tahap input, proses dan output. SIP2TB berbasis wilayah dirancang nntuk kemudahan input data dan otomasi proses pengolahannya menjadi informasi. Output yang dihasilkan berupa laporan reguler, tabulasi indikator program, grafik indikator program dan informasi pemetaan endemisitas wilayah dengan unit pengamatan terkecil desa. Interpretasi epidemiologis kasus TB pada visual peta ini dapat mengetahui jangkauan pelayanan kesehatan (Puskesmas) dalam penanggulangan TB dari kepadatan penduduk dengan sebaran kasus TB. Aplikasi SIP2TB ini dapat menjadi alat manajemen dalam program penanggulangan TB, menguatkan kemarnpuan pada kegiatan monitoring dan evaluasi. Output yang dihasilkan dapat dijadikan informasi untuk masukan pada pengambil keputusan dalam program Penanggulangan TB. SIP2TB ini diharapkan dapat dijadikan alat bagi pengelola program dan bila memungkinkan dapat dikembangkan di puskesmas sarta menjadi model bagi kabupaten lain.

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Tuberculosis (TB) is a communicable disease caused by Mycobacterium tuberculosis that it is still beeing a public health problem in the community. Number of detected new smear positive pulmonary TB were 1,095 cases in Subang district by the year 2006 referred to the national incidencerate, 107/100,000. Over the last five year there were an increased number of detected all type TB cases in Subang district. This showed that TB still becomes a public health problem in the community.

TB Control Program in Subang has been carrying out "ball pick up" for TB data colection in district level. It means that district TB supervisor (wasor) goes to health services unit to pick up data or registry when quarterly supervisory visit. This system might cause the data differences between the real existing data at health service unit (UPK) and collected data by wasor at the same period of time if the wasor visit UPK at the begining or in the middle of the quarter.

System Development was done on the basis of System Development Life Cycle method, including planning analysis system, design, implementation, maintenance and evaluation system. Through combining the concept of Data Base Management System and integrated with spatial data able to increased an advances of TB Control Program Geographical Information System in Subang district. Result system analysis was able to identify the management information system of TB control program as well as alternative solution on input phase, process phase and output phase.

The GISTB was designed to make input data and data processing to be information becoming easier. The output is a regular report, tables, graphs of the program indicators as well as information mapping of TB case distribution in village level as an investigation unit. Epidemilogy Interpretation of TB case on the visual map shows the level of health center coverage in relation to TB services. It also shows the population density and case distribution.

The GISTB application will be able become as a management tool of TB control program for strengthening monitoring and evaluation system. Therefore a decision making for TB control program in Subang based on valid, acurate and reliable data as an output of the system. This system also is expected to be able to be adopted as a wasor tools and expanded to health service unit level as well as being a model in other districts."

"Tuberkulosis merupakan masalah kesebatan masyarakat di Indonesia, karena dapat menyebabkan kematian. Untuk penanggulangan penyakit tuberculosis, pemerintah telah melaksanakan Strategi DOTS (Directly Observed Treatment Shortcourse). Pengobatan yang baik dan teratur dapat menyembubkan penderita TB Paru. Penderita TB Paru dapat mengalami DO (Drop Out), bila pengobatan tidak baik dan tidak teratur. Angka DO di Balai Kesehatan Paru Masyarakat Kota Bandung pada tahun 2005 adalah 11,6 %. Tujuan dari penelitian ini adalah untuk mengetahui faktor faktor yang berhubungan dengan terjadinya DO pada penderita TB Paru di Balai Kesehatan Paru Masyarakat tahun 2007. Penelitian ini menggunakan data primer dengan desain kasus kontrol dan dilakukan pada penderita TB Paru yang berasal dari Kota Bandung dan berobat di Balai Kesehatan Pam Masyarakat dengan jumlah sampel kasus 115 responden dan kontrol sebanyak 115 responden. Kasus adalah penderita TB Paru yang Drop Oul, sedangkan kontrol adalah penderita TB Paru yang tidak Drop Out. Pada penelitian ini variabel yang berhubungan dengan terjadinya Drop Out adalah pengetahuan, biaya dan keberadaan PMO. Pengetahuan mempunyai OR =5,2 dengan 95% C T: 2,79-9,80 berarti bahwa penderita TB Paru dengan pengetahuan yang kurang barisiko 5,2 kali menjadi DO bila dibandingkan dengan pengetahuan yang baik setelah dikontrol variabel biaya dan PMO. Variabel biaya mempunyai OR= 3,4 dengan 95% CI: 1,80-6,23 berarti bahwa penderita dengan presepsi biaya mahal berisiko 3,4 kali bila dibandingkan dengan penderita dengan presepsi biaya murah, setelah dikontrol variabel pengetahuan dan PMO Variabel keberadaan PMO mempunyai OR= 2,2 dengan 95% CI: 1,16-4,05 berarti bahwa penderita yang tidak mempunyai PMO berisiko 2,2 kali bila dibandingkan dengan penderita yang mempunyai PMO setelah dikontrol variabel pengetahuan dan biaya.

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Tuberculosis is a public health problem in Indonesia due to the life threatening nature of the disease, To contro) tuberculosis, the government has implemented DOTS (Directly Observed Treatment Short-course) Strategy, Good and regular treatment can cure lung TB patients. Lung TB patients, will be DOs (Drop Outs) when the treatment is not performed well and regularly The DO rate at the Balal Kesehalan Paru Masyarakot (Public Lung Health Center), Bandung City in 2005 was 11,6 %, The aim of this study is to know factors related 10 Lung TB patient drop outs in Ball'; Kesehatan Par" Masyarakat in 2007.

The study is conducted using primary data with case control design and was performed to Lung TB patients who came from Bandung City and who were treated at Balai Kesehatan Poru }Jasyarakaf with a sample size of 115 case respondents and 115 control respondents. The case respondents consist of Lung TB patients who drop out while the control respondents consist of Lung TB patients who do not drop out of treatment.

The variables relationship with happened of Lung TB patients who drop OUT in this research arc knowledge, cost, and the presence of drug observer. Knowledge has an OR of 5.2 with 95% Cl: 2.80-9,80 meaning that a Lung TB patient whose knowledge is poor has 5.2 times more risk to DO compared to those with good knowledge after the cost and drug observer variab1es are controlled, The cost variable has an OR of 3.4 with 95% Cl: 1.80 -6.23 meaning that patients with a perception of high cost have 3.4 more risk compared to patients with a perception of low cost after the knowledge and drug observer variables are controlled. The presence of drug observer variable has an OR of 2.2 with 95% CI: L160-4.049 meaning that patients who do not have drug observer has 2.2 times more risk compared to patients with drug observer after the knowledge and cost variables are controlled."

"Tuberkulosis merupakan salah satu penyakit menular yang banyak dialami oleh masyarakat perkotaan. Rentannya masyarakat perkotaan terhadap kejadian tuberkulosis salah satunya dipengaruhi oleh lingkungan perkotaan yang padat dan lembab. Tuberkulosis tidak hanya memberikan dampak fisik terhadap penderitanya, akan tetapi berdampak pula terhadap keadaan psikososial. Masalah psikososial yang sering muncul terkait penyakit tuberkulosis adalah ansietas. Tujuan penulisan ini adalah melakukan analisis evidence based mengenai teknik relaksasi khususnya tarik napas dalam dan distraksi dengan mendengarkan musik untuk mengatasi ansietas pada penderita tuberkulosis. Hasil dari pemberian teknik relaksasi pada klien dengan tuberkulosis terbukti efektif untuk menurunkan ansietas yang dideritanya. Rekomendasi penulisan ini adalah perawat perlu mengajarkan teknik relaksasi kepada klien tuberkulosis dengan ansietas sedini mungkin agar proses penyembuhan klien menjadi lebih optimal.

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Tuberculosis is one of the infectious disease that is often happened in urban communities. Vulnerability of urban communities on the incidence of tuberculosis is affected by dense urban environments and moist. The disease has an impact on the overall well-being of the patient, which is affecting not only the physical impact but also psychosocial. Anxiety is one of the psychosocial problem that is often related to the disease. The purpose of this paper is to analyze evidence based on relaxation techniques in particular relaxation breathing exercise and distraction especially listening music to overcome anxiety in patients with tuberculosis. The results of the intervention in these patients showed that the intervention is effective to reduce anxiety. Recommendation of this paper is that nurse should teach relaxation techniques to patients with tuberculosis as soon as possible to allow the optimal healing."

"Urbanisasi telah menyebabkan perpindahan penduduk dari desa ke kota. Karakteristik lingkungan perkotaan yang padat penduduk dan disertai dengan lingkungan yang kotor dan kumuh mengakibatkan peningkatan penyebaran penyakit infeksius seperti Tuberkulosis Paru. Masalah psikososial yang sering muncul pada pasien dengan penyakit kronis seperti Tuberkulosis Paru dan Diabetes Mellitus adalah ketidakberdayaan. Ketidakberdayaan adalah perasaan hilangnya kontrol terhadap kondisi dan situasi yang dimiliki oleh seorang individu akibat adanya hambatan untuk mengembangkan potensi dan kekuatan yang dimiliki. Faktor penyakit kronis, beban penyakit, lama pengobatan, dan tidak adanya dukungan keluarga telah menimbulkan masalah ketidakberdayaan pada Ny. Y dengan Tuberkulosis Paru dan Diabetes Mellitus di Ruang Gayatri RS Dr. H. Marzoeki Mahdi Bogor. Intervensi keperawatan berupa afirmasi positif telah terbukti menurunkan tanda gejala ketidakberdayaan pada klien dengan kedua diagnosa medis tersebut.

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Urbanization has caused a movement of population from country to town. The characteristic of urban environment with huge population and slum area could cause the escalation of pulmonary tuberculosis transmission as one of infectious diseases. Powerlessness is one of psychosocial problems often showed in chronic illness patient such as diabetes mellitus and pulmonary tuberculosis. Powerlessness is the lived experience of lack of control over a situation, including a perception that one?s actions do not significantly affect an outcome. Chronic illness, long period of medical treatment, and inadequate of family support have became the predisposition factors of powerlessness in Mrs. Y with pulmonary tuberculosis and diabetes mellitus at Gayatri Room in Marzoeki Mahdi Bogor Hospital. Positive affirmation as the main intervention in powerlessness has been proved to decrease symptoms of powerlessness on chronic illness patient."

"[ABSTRAKSerial kasus ini bertujuan untuk mempelajari dan menerapkan terapi nutrisi sebagai bagian dari terapi tuberkulosis (TB) paru. Komplikasi yang menyertai TB paru dapat meningkatkan morbiditas dan mortalitas. Seluruh pasien serial kasus ini dalam kondisi malnutrisi dan terdapat komplikasi yang menyertai masingmasing kasus berupa drug-induced hepatotoxicity, peritonitis TB, diabetes melitus tipe 2, dan pneumotoraks dengan dispepsia. Pemberian nutrisi disesuaikan dengan kondisi, penyakit penyerta, dan kebutuhan yang bersifat individual. Kebutuhan energi basal dihitung dengan persamaan Harris-Benedict dengan kebutuhan energi total setara dengan 35?40 kkal/kg BB. Makronutrien diberikan dalam komposisi seimbang dengan protein 15?20% kebutuhan energi (1,2?1,5 g/kg BB). Saran pemberian mikronutrien minimal mencapai angka kecukupan gizi. Pasien yang mendapat obat antituberkulosis berupa isoniazid disarankan mendapat suplementasi vitamin B6 dengan dosis tertentu untuk mencegah neuritis perifer. Outcome yang dinilai meliputi kondisi klinis, asupan, dan toleransi asupan. Pemberian terapi nutrisi sebagian besar pasien dimulai dari kebutuhan energi basal yang pada akhir masa perawatan dapat mencapai target kebutuhan energi total. Pemantauan jangka panjang pasca rawat inap, disarankan tidak hanya menilai outcome berdasarkan perubahan berat badan, namun dilakukan penilaian komposisi tubuh, terutama massa lemak, karena pada kasus TB terjadi abnormalitas metabolisme yang disebut anabolic block.

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ABSTRACTThe aim of this case series was to study and apply nutrition therapy as integral part of pulmonary tuberculosis (TB) therapy. Pulmonary TB with complications was associated with increased of morbidity and mortality. Malnutrition was coexisted with several complications such as drug-induced hepatotoxicity, peritoneal TB, type 2 diabetes mellitus, and pneumothorax with dyspepsia. HarrisBenedict equation was used to calculate basal energy requirement with total energy requirement equivalent to 35?40 kcal/body weight. Balanced macronutrient composition was given with protein 15?20% energy requirement (1,2?1,5 g/body weight). Micronutrient recommendation was given to fulfill one fold recommended daily allowance. Patients with isoniazid therapy needed to get pyridoxine supplementation to prevent peripheral neuritis. Outcome measurements included clinical condition, amount of intake, and intake tolerance. Most patients were given initial nutrition therapy from basal energy requirement and has shown increment. At the end of hospitalization, all of patients could achieve total energy requirement. Due to abnormality of metabolism, usually termed as anabolic block, it was recommended not only to measure body weight as primary outcome, but also body composition., The aim of this case series was to study and apply nutrition therapy as integral part of pulmonary tuberculosis (TB) therapy. Pulmonary TB with complications was associated with increased of morbidity and mortality. Malnutrition was coexisted with several complications such as drug-induced hepatotoxicity, peritoneal TB, type 2 diabetes mellitus, and pneumothorax with dyspepsia. HarrisBenedict equation was used to calculate basal energy requirement with total energy requirement equivalent to 35–40 kcal/body weight. Balanced macronutrient composition was given with protein 15–20% energy requirement (1,2–1,5 g/body weight). Micronutrient recommendation was given to fulfill one fold recommended daily allowance. Patients with isoniazid therapy needed to get pyridoxine supplementation to prevent peripheral neuritis. Outcome measurements included clinical condition, amount of intake, and intake tolerance. Most patients were given initial nutrition therapy from basal energy requirement and has shown increment. At the end of hospitalization, all of patients could achieve total energy requirement. Due to abnormality of metabolism, usually termed as anabolic block, it was recommended not only to measure body weight as primary outcome, but also body composition.]"

"[ABSTRAKLatar Belakang : Penggunaan efavirenz dan rifampisin secara bersamaan menjadi suatu tantangan dalam penanganan HIV/AIDS-Tuberkulosis. Rifampisin sebagai penginduksi enzim pemetabolisme efavirenz dapat menurunkan kadar plasma efavirenz, dan dapat menyebabkan gagal terapi HIV.Tujuan: Penelitian ini dilakukan untuk mengetahui pengaruh rifampisin terhadap kadar plasma efavirenz dan viral load viral load pasien HIV/AIDS-Tuberkulosis yang telah mendapat terapi antiretrovirus 3-6 bulan. Metode : Penelitian ini mengukur kadar efavirenz dan viral load pasien HIV/AIDS yang mendapat antiretroviral berbasis efavirenz dosis 600 mg/hari setelah 3-6 bulanterapi dan pasien HIV/AIDS-Tuberkulosis dengan terapi antiretroviral yang sama dan terapi antituberkulosis berbasis rifampisin di RSPI Prof. DR Sulianti Saroso, hasilnya akan dibandingkan. Hasil : Subjek penelitian berjumlah 45 pasien, terdiri dari 27 pasien kelompok HIV/AIDS dan 18 pasien kelompok HIV/AIDS-Tuberkulosis. Pada pemeriksaan kadar plasma efavirenz didapat median (min-maks) kelompok HIV/AIDS 0,680 mg/L (0,24-5,67 mg/L), median (min-maks) kadar plasma kelompok HIV/AIDS-Tuberkulosis 0,685 mg/L (0,12-2,23 mg/L), berarti tidak terdapat perbedaan kadar plasma efavirenz yang bermakna secara statistik antara kedua kelompok (MannWhitney, p=0,480). Proporsi pasien dengan viral load ≥ 40 kopi/ml pada kelompok HIV/AIDS sebesar 51,9%, sedangkan pada kelompok HIV/AIDS-Tuberkulosis sebesar 72,2% (ChiSquare, p=0,291), tidak terdapat perbedaan proporsi pasien yang viral load < 40 kopi/ml maupun ≥ 40 kopi/ml antar kelompok. Tidak terdapat perbedaan secara statistik (Chi Square, p=0,470) antara proporsi pasien yang mempunyai kadar subterapetik dalam kelompok, dengan hasil viral load < 40 kopi/ml (45,2%) maupun ≥ 40 kopi/ml (54,8%). Kesimpulan: Kadar plasma efavirenz maupun viral load pasien HIV/AIDS-Tuberkulosis yang mendapat antiretroviral bersama antituberkulosis berbasis rifampisin tidak berbeda bermakna dengan pasien HIV/AIDS setelah 3-6 bulan terapi antiretroviral.

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ABSTRACTBackground: Concomitant use of efavirenz and rifampicin is a challenge in the treatment of HIV/AIDS-Tuberculosis infection. Rifampicin may decrease plasma concentration of efavirenz through induction of its metabolism, and could lead to HIV treatment failure Objective: To determine the effect of rifampicin-containing tuberculosis regimen on efavirenz plasma concentrations and viral load in HIV/AIDS-Tuberculosis infection patients who received efavirenz-based antiretroviral therapy. Methods: plasma efavirenz concentrations and HIV viral load were measured in HIV/AIDS patients treated with 600 mg efavirenz-based antiretroviral for 3 to 6 months and in HIV/AIDS-Tuberculosis infection patients treated with similar antiretroviral regimen plus rifampicin-containing antituberculosis in Prof. DR. Sulianti Saroso, Hospital Jakarta, Indonesia, The results were compared Results: Forty five patients (27 with HIV/AIDS and 18 with HIV/AIDSTuberculosis infections) were recruited during the period of March to May 2015. The median (min-max) efavirenz plasma concentration obtained from HIV/AIDS group [0,680 mg/L(0,24 to 5,67 mg/L] and that obtained from HIV/AIDSTuberculosis group[0.685 mg/L (0.12 -2.23 mg/L)] was not significantly different (Mann-Whitney U test, p = 0.480) .The proportion of patients with viral load ≥ 40 copies/ml after 3-6 months of ARV treatment in the HIV/AIDS group (51.9%), and the HIV/AIDS-Tuberculosis group (72.2%) was not significantly different (Chi Square test, p = 0.291). There was no significant difference (Chi Square, p=0,470) between the proportions of patients with subtherapeuticefavirenz plasma concentration in the groups with viral load < 40 copies/mL (45,2%) and ≥ 40 copies/mL (54,8%) Conclusions: Plasma efavirenz concentrations and viral load measurements in HIV/AIDS-Tuberculosis patients in antiretroviral and rifampicin-containing antituberculosis regimen were not significantly different with those in HIV/AIDS patients in 3 to 6 months antiretroviral therapy., Background: Concomitant use of efavirenz and rifampicin is a challenge in the treatment of HIV/AIDS-Tuberculosis infection. Rifampicin may decrease plasma concentration of efavirenz through induction of its metabolism, and could lead to HIV treatment failure Objective: To determine the effect of rifampicin-containing tuberculosis regimen on efavirenz plasma concentrations and viral load in HIV/AIDS-Tuberculosis infection patients who received efavirenz-based antiretroviral therapy. Methods: plasma efavirenz concentrations and HIV viral load were measured in HIV/AIDS patients treated with 600 mg efavirenz-based antiretroviral for 3 to 6 months and in HIV/AIDS-Tuberculosis infection patients treated with similar antiretroviral regimen plus rifampicin-containing antituberculosis in Prof. DR. Sulianti Saroso, Hospital Jakarta, Indonesia, The results were compared Results: Forty five patients (27 with HIV/AIDS and 18 with HIV/AIDSTuberculosis infections) were recruited during the period of March to May 2015. The median (min-max) efavirenz plasma concentration obtained from HIV/AIDS group [0,680 mg/L(0,24 to 5,67 mg/L] and that obtained from HIV/AIDSTuberculosis group[0.685 mg/L (0.12 -2.23 mg/L)] was not significantly different (Mann-Whitney U test, p = 0.480) .The proportion of patients with viral load ≥ 40 copies/ml after 3-6 months of ARV treatment in the HIV/AIDS group (51.9%), and the HIV/AIDS-Tuberculosis group (72.2%) was not significantly different (Chi Square test, p = 0.291). There was no significant difference (Chi Square, p=0,470) between the proportions of patients with subtherapeuticefavirenz plasma concentration in the groups with viral load < 40 copies/mL (45,2%) and ≥ 40 copies/mL (54,8%) Conclusions: Plasma efavirenz concentrations and viral load measurements in HIV/AIDS-Tuberculosis patients in antiretroviral and rifampicin-containing antituberculosis regimen were not significantly different with those in HIV/AIDS patients in 3 to 6 months antiretroviral therapy.]"