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"Tanah longsor translasi dianggap lebih jarang terjadi daripada tanah longsor rotasi. Akibatnya, tidak banyak publikasi tentang masalah ini. Menurut penelitian sebelumnya, salah satu program perangkat lunak yang digunakan selama penelitian mengalami masalah. Penelitian ini menguji kompatibilitas dua program perangkat lunak menggunakan dua cara berbeda untuk menghitung nilai faktor keamanan. Seperti untuk Metode Elemen Hingga, MIDAS GTS NX, dan untuk Metode Kesetimbangan Batas, GeoSlope. Fokus hanya pada aspek geometris longsor, seperti sudut kemiringan, elevasi air, dan rasio ketebalan tanah terhadap tinggi lereng. Selanjutnya, penelitian membedakan antara dua jenis tanah. Temuan utama studi ini menunjukkan bahwa masalah utama bukan pada input perangkat lunak. Sebaliknya, kedua program tidak dikembangkan untuk menghitung faktor keamanan slide translasi. Hal ini menunjukkan bahwa hasil faktor keamanan mendekati perhitungan manual ketika ilustrasi bidang keruntuhan kritis menunjukkan geseran rotasi. Rekomendasi dari penelitian ini dalam menentukan faktor keamanan longsor translasi adalah dengan Metode Limit Equilibrium menggunakan software GeoSlope karena hasil dari GeoSlope lebih akurat dibandingkan dari MIDAS GTS NX.

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Translational landslides are thought to be more uncommon than rotational landslides. As a result, there are not many publications on the subject. According to previous studies, one of the software programs employed throughout the study encountered an issue. This research examined the compatibility of two software programs using two distinct ways to calculate the safety factor value. Such as for the Finite Element Method, MIDAS GTS NX, and for the Limit Equilibrium Method, GeoSlope. Focus solely on the geometrical aspects of the landslide, such as the slope angle, water elevation, and the ratio of soil thickness to slope height. Furthermore, the research distinguishes between two types of soil. The study's primary finding shows that the main issue was not with the software's input. Instead, both programs were not developed to calculate the safety factor of a translational slide. It shows that the result of the safety factor is close to the manual calculation when the illustration of the critical failure plane shows a rotational slide. The recommendation from this study in determining the factor of safety of a translational landslide is by Limit Equilibrium Method using the GeoSlope software since the result from GeoSlope is more accurate than from MIDAS GTS NX. "

"This updatable book provides an accessible informative overview of the current state of the art in nerve repair research.The introduction includes history of nerve repair research and establishes key concepts and terminology and will be followed by sections that represent the main areas of interest in the field: (1) Biomaterials, (2) Therapeutic Cells, (3) Drug, Gene and Extracellular Vesicle Therapies, (4) Research Models and (5) Clinical Translation. Each section will contain 3 - 6 chapters, capturing the full breadth of relevant technology. Bringing together diverse disciplines under one overarching theme echoes the multidisciplinary approach that underpins modern tissue engineering and regenerative medicine. Each chapter will be written in an accessible manner that will facilitate interest and understanding, providing a comprehensive single reference source. The updatable nature of the work will ensure that it can evolve to accommodate future changes and new technologies. The main readership for this work will be researchers and clinicians based in academic, industrial and healthcare settings all over the world."

"Translasi radiofarmaka dari hewan percobaan ke dosis manusia merupakan tugas yang menantang karena variasi biologis antar spesies dan kurangnya standarisasi dalam dosimetri kedokteran nuklir. Studi ini berfokus pada pengaruh seleksi model terhadap perhitungan dosis yang diserap radiasi pada kasus translasi biokinetik dari hewan ke manusia. Penelitian ini menggunakan data biokinetik rata-rata dan individu dari studi radiofarmaka 177Lu-OPS201 pada hewan dan manusia dengan menggunakan model Sum of Exponential (SoE). Analisis Goodness of Fit (GoF) dan corrected Akaike Information Criterion (AICc) digunakan untuk seleksi model. Model f_2 (t)=A_1 e^(-(λ_1+λ_phys )t) terpilih sebagai model terbaik untuk mencit, babi, dan manusia. Penggunaan data biokinetik rata-rata menghasilkan %wAICc sebesar 50,01%, TIAC referensi sebesar 5,41±0,29 jam (manusia), 1,35±0,07 jam (mencit), dan 2,23±0,17 jam (babi). Sementara penggunaan data biokinetik individu menghasilkan %wAICc sebesar 84,00%, TIAC referensi sebesar 5,41±0,24 jam (manusia), 1,35±0,07 jam (mencit), dan 1,68±0,12 jam - 2,85±0,28 jam (babi). Metode regresi linear dan allometric scalling digunakan dalam proses translasi biokinetik radiofarmaka 177Lu-OPS201 dari hewan ke manusia. Hasilnya, model terbaik dengan data biokinetik rata-rata dapat memprediksi TIAC sebesar 5,45±0,03 jam dan akurasi 99,20% mendekati referensi (regresi linear) dan TIAC prediksi sebesar 3,97±1,01 jam dan akurasi 73,50% mendekati referensi (allometric scalling).

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The translation of radiopharmaceuticals from experimental animals to human doses is a challenging task due to biological variations between species and lack of standardization in nuclear medicine dosimetry. This study focuses on the influence of model selection on the calculation of radiation absorbed dose in the case of biokinetic translation from animals to humans. This study used average and individual biokinetic data from the 177Lu-OPS201 radiopharmaceutical study in animals and humans using the Sum of Exponential (SoE) model. Goodness of Fit (GoF) analysis and corrected Akaike Information Criterion (AICc) were used for model selection. The model f_2 (t)=A_1 e^(-(λ_1+λ_phys )t) was selected as the best model for mice, pigs and humans. The use of average biokinetic data resulted in %wAICc of 50.01%, reference TIAC of 5.41±0.29 hours (human), 1.35±0.07 hours (mice), and 2.23±0.17 hours (pigs). Meanwhile, the use of individual biokinetic data resulted in a %wAICc of 84.00%, a reference TIAC of 5.41±0.24 hours (human), 1.35±0.07 hours (mice), and 1.68±0.12 hours - 2.85±0.28 hours (pigs). Linear regression and allometric scaling methods were used in the process of translating the biokinetics of radiopharmaceutical 177Lu-OPS201 from animals to humans. As a result, the best model with average biokinetic data can predict TIAC of 5.45±0.03 hours and 99.20% accuracy close to the reference (linear regression) and predicted TIAC of 3.97±1.01 hours and 73.50% accuracy close to the reference (allometric scalling)."