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Abstrak :
Pengecekan akurasi kualitas citra dalam program kontrol kualitas quality control, QC dapat ditingkatkan dengan penggunaan fantom yang mendekati kondisi realistis pada pemindaian klinis. Penelitian ini ditujukan untuk mengembangkan fantom desain khusus yang terdiri dari material organik ekuivalen-hati dan otot jaringan lunak . Karakterisasi sifat radiologi material ekuivalen jaringan menunjukan bahwa material ekuivalen jaringan lunak otot yang tersusun atas campuran Gondorukem, Malam Cecek, dan tepung beras dengan rasio massa 70/20/10 memiliki CT Number -20.27 0.33 HU, densitas massa 1.055 g/cm3 dan densitas elektron 3.461 1023 e/m3. Material ekuivalen jaringan hati yang tersusun atas campuran Malam Cecek dan tepung beras dengan rasio massa 60/40 memiliki CT Number 74.17 1.48 HU, densitas massa 1.024 g/cm3 dan densitas elektron 3.396 1023 e/m3. Penggunaan fantom desain khusus dalam mengevaluasi kualitas citra PET berdasarkan parameter full-width-half-maximum FWHM resolusi dan signal-to-noise ratio SNR menunjukan bahwa detektabilitas sistem pemindaian PET bergantung terhadap ukuran pixel dan metode rekonstruksi citra yang digunakan. Sistem pencitraan PET/CT Siemens Biograph dengan rekonstruksi True-X dan filter Butterworth menggunakan ukuran pixel 1 x 1 mm2, memberikan ukuran obyek pada citra PET lebih kecil daripada ukuran obyek sebenarnya, kecuali pada obyek 4.02 mm. Sistem pemindaian PET/CT Philips Gemini TOF 16 dengan ukuran pixel 4 x 4 mm2 menunjukan adanya perbesaran ukuran obyek kecil dengan diameter kurang dari 16 mm. Kedua pesawat PET/CT menunjukan bahwa ukuran obyek pada citra cenderung lebih kecil atau mencapai threshold 80 dari ukuran sebenarnya pada obyek berdiameter lebih besar sama dengan 16.30 mm. Sebaliknya, overestimation nilai FWHM terjadi pada obyek berukuran kecil 4.20 mm sebagai akibat dari terjadinya partial volume effect. Studi pengukuran kualitas citra dengan fantom desain khusus ini menunjukan bahwa pemilihan metode rekonstruksi, filter post processing, dan ukuran pixel mempengaruhi resolusi atau detektabilitas dan SNR pada citra PET. Pada akhirnya, fantom desain khusus ini mampu memberikan analisa kualitas.

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The purpose of this research was to develop a phantom for quality control QC of PET CT image quality. The phantom was constructed by tissue equivalent materials which consist six cylindrical hot lesions with diameter of 4.20, 6.20, 8.30, 9,80, 16.30, and 19.00 mm. Wax and rice starch were combined to produce the tissue equivalent materials. The results showed that combination 70 20 10 of gondorukem cecek wax rice starch and 60 40 of cecek wax rice starch yielded liver and muscle surrogate materials respectively. Liver equivalent material LEM was 74.17 1.48 HU, 1.024 g cm3 of mass density, and 3.396 1023 e m3 of electron density. While, muscle equivalent material MEM was 20.27 0.33 HU, 1.055 g cm3 of mass density and 3.461 1023 e m3 of electron density. Then, the phantom was scanned using two different PET CT scanner to determine the detectability and signal to noise ratio SNR as measure PET CT imaging performance. It showed that the detectability of PET CT scanner was affected by pixel size and reconstruction method for image acquisitions. For Siemens Biograph PET CT scanned using pixel sixe of 1 1 mm2, FWHMs were smaller than the actual size of the hot lesions. Meanwhile, for Philips Gemini PET CT scanned using pixel sixe of 4 4 mm2, FWHMs were larger than the actual size of the hot lesions. For both PET CT scanner, ratio of FWHM actual size reached the threshold of 80 at object diameter ge 16.30 mm. In contrast, overestimation of FWHM occurred at smaller object diameter 4.20 mm significantly caused by the partial volume effect. The study also indicated that image reconstructions, post processing smoothing filter, and pixel size may give impact to the detectability and SNR performed by a PET CT system. It was concluded that the phantom could be used to analyze the image quality performance in PET CT imaging.

Abstrak :
Fantom merupakan material ekuivalen jaringan tubuh yang berfungsi untuk menyimulasikan interaksi radiasi yang terjadi. Keberadaan fantom di bidang medis menjadikan proses quality assurance (QA), quality control (QC) dan treatment planning system tidak perlu mengekspos jaringan tubuh asli. Tujuan dari penelitian ini adalah menentukan komposisi fantom organik (berbahan dasar lilin dan karbon aktif) juga memperoleh nilai exit dose fantom organik melalui variasi ketebalan serta korelasinya terhadap koefisien atenuasi. Komposisi fantom tersebut didapatkan melalui kesesuaian terhadap nilai CT number (dalam satuan HU) jaringan tubuh manusia. Komposisi bahan organik penyusun fantom berdasarkan penelitian ini untuk material ekuivalen lemak adalah 10% lilin cecek, 10% karbon dan 80% lilin parafin, otot 10% lilin cecek, 10% karbon dan 80% gondorukem, otak white matter 16% lilin cecek, 16% karbon dan 68% gondorukem, otak grey matter 20% lilin cecek, 20% karbon dan 60% gondorukem dan hati 40% tepung beras, dan 60% lilin cecek. Pengukuran exit dose dilakukan pada ketebalan fantom mulai dari 6 cm hingga 10 cm serta ukuran lapangan 20 cm × 20 cm dan 25 cm × 25 cm. Persentase penurunan nilai exit dose di ketebalan 10 cm relatif terhadap ketebalan 6 cm pada ukuran lapangan 20 cm x 20 cm menunjukkan nilai sebesar (29,1% ± 4,4%); (43,7% ± 2,7%); (43,0% ± 1,2%); (41,4% ± 0,4%); (51,2% ± 5,7%) untuk material ekuivalen jaringan lemak, otot, otak white matter, otak grey matter, dan hati secara berturut – turut. Sedangkan pada ukuran lapangan 25 cm × 25 cm menunjukkan nilai sebesar (30,0% ± 2,3%); (41,2% ± 2,6%); (41,9% ± 2,1%); (40,4% ± 1,1%); (47,5% ± 4,7%). Berdasarkan hasil tersebut menunjukkan bahwa, nilai exit dose berkurang seiring dengan bertambahnya ketebalan fantom. Hal serupa ditunjukkan oleh pengurangan ukuran lapangan yang menyebabkan berkurangnya nilai exit dose. Sementara itu, nilai dosis serap dan buildup factor menunjukkan hasil yang bertolak belakang dengan nilai exit dose, di mana penambahan ketebalan fantom menyebabkan naiknya dosis serap.

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Phantom is an equivalent body tissue material that has always been used to simulate radiation interactions. the needs to expose human body with radiation in the process of QA, QC, and treatment planning system is no longer needed since the existence of phantom in the medical field. The purpose of this study is to determine the composition of organic phantom (wax and activated carbon) and also obtain the value of the exit dose of organic phantom through variations in thickness and its correlation to the attenuation coefficient. The phantom composition was obtained through conformity to the value of the CT number (in HU unit) human body tissue. The composition of the organic phantom for fat is 10% cecek wax, 10% activated carbon and 80% paraffin wax, muscle 10% cecek wax, 10% activated carbon and 80% gondorukem, brain white matter 16% cecek wax, 16% activated carbon and 68% gondorukem, brain gray matter 20% cecek wax, 20% activated carbon and 60% gondorukem and liver 40% rice flour, and 60% gondorukem wax. Exit dose was measured with phantom thickness variations ranging from 6 cm to 10 cm and field sizes of 20 cm × 20 cm and 25 cm × 25 cm. The decrease in percentage of exit dose based on thickness increment of the size of the field 20 cm x 20 cm were (29,1% ± 4,4%); (43,7% ± 2,7%); (43,0% ± 1,2%); (41,4% ± 0,4%); (51,2% ± 5,7%) for equivalent material fat, muscle, white matter brain, gray matter brain, and liver respectively. Whereas the size of the field 25 cm × 25 cm were (30,0% ± 2,3%); (41,2% ± 2,6%); (41,9% ± 2,1%); (40,4% ± 1,1%); (47,5% ± 4,7%). Based on these results it showed that the value of the exit dose decreases with increasing thickness of the phantom. The same results were showed by the reduction in the size of the field which causes a decrease in the value of exit dose. Meanwhile, the absorption dose value and buildup factor showed the opposite results with the exit dose value, where the phantom thickness increment.