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"Real-time prediction of process quality is the key factor for guaranteeing product performance static modeling method could not consider the impact of noise variables on quality characteristics, which will easily lead quality problem for instability. This paper proposes a dynamic quality modeling and prediction approach for multivariable process using nonlinear dynamical analysis. The quality state model any time of process is regarded as an evolution product obtained from the adjacent previous moment. Dual extended Kalman filter algorithm is introduced to real-time adjust the quality prediction model, which refers to the weights and the centers in radial basis function network. So the dynamic adaptive neutral network is proposed to predict the following state of quality. Finally, a case about crack prediction of continuous casting slab is conducted to illustrate the feasibility of proposed approach, result shows that it could accurately crack the nonlinear dynamic continuous casting process."

"This paper is housed on contraceptive switching in indonesia. Since a woman might use more than one method of contraception during her reproductive period she can contribute more than one contraceptive use interval to the data. Some studies of contraceptive switching have used statistical techniques which assume independence between switching but this assumption can be violated because the likelihood of switching might be correlated. Hence contraceptive switching varies not only across groups of contraceptive users but also across contraceptive users with the same socioeconomic characteristics. Hence the consequences of this contraceptive users' eject for the relationship between socioeconomic. demographic and contraceptive-related characteristics of users and contraceptive switching in indonesia is analysed through the use of random-ejects logistic models. The data used for the analysis is from the 1991 Indonesia Demographic and Health Survey. The findings confirm the results of previous studies that a number of socioeconomic and demographic factors influence the likelihood of switching contraception. Among these factors. contraceptive-related /actors such as the method being used before switching, the duration of use at switching and the reason for switching, affect contraceptive switching most. The results also indicate that there is correlation between intervals for the same woman. This implies that there are other factors which have not been observed and contribute to the differentials of switching contraception across women with the saute socioeconomic characteristics."

"This book is an edited volume, the goal of which is to provide an overview of the current state-of-the-art in statistical methods applied to problems in structural bioinformatics (and in particular protein structure prediction, simulation, experimental structure determination and analysis). It focuses on statistical methods that have a clear interpretation in the framework of statistical physics, rather than ad hoc, black box methods based on neural networks or support vector machines. In addition, the emphasis is on methods that deal with biomolecular structure in atomic detail. Therefore, the book includes introductory chapters that contain a solid introduction to key topics such as Bayesian statistics and concepts in machine learning and statistical physics."

"This is the fifth edition of a very successful textbook on clinical trials methodology, written by recognized leaders who have long and extensive experience in all areas of clinical trials. The three authors of the first four editions have been joined by two others who add great expertise. Most chapters have been revised considerably from the fourth edition. A chapter on regulatory issues has been included and the chapter on data monitoring has been split into two and expanded. Many contemporary clinical trial examples have been added. There is much new material on adverse events, adherence, issues in analysis, electronic data, data sharing, and international trials. This book is intended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must critically evaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of patients. The authors use numerous examples of published clinical trials to illustrate the fundamentals.The text is organized sequentially from defining the question to trial closeout. One chapter is devoted to each of the critical areas to aid the clinical trial researcher. These areas include pre-specifying the scientific questions to be tested and appropriate outcome measures, determining the organizational structure, estimating an adequate sample size, specifying the randomization procedure, implementing the intervention and visit schedules for participant evaluation, establishing an interim data and safety monitoring plan, detailing the final analysis plan, and reporting the trial results according to the pre-specified objectives."

"Covers the spectrum of research design strategies, from material presented in introductory classes to topics necessary in graduate researchAddresses cross- and multidisciplinary research needs, with many examples drawn from the social and behavioral sciences, neurosciences, and biomedical and life sciencesProvides summaries of advantages and disadvantages of often-used strategiesUses hundreds of sample tables, figures, and equations based on real-life cases. The Encyclopedia of Research Design is the perfect instrument for new learners as well as experienced researchers to explore both the original and newest branches of the field."