Hasil Pencarian  ::  Simpan CSV :: Kembali

"Fungsi seksual merupakan salah satu komponen kualitas hidup yang harus dipenuhi oleh manusia. Histerektomi yang merupakan aspek prosedur operatif pada perempuan dapat mengubah anatomi, hormonal, serta psikologis yang dapat menimbulkan gangguan pada fungsi seksual. Penelitian ini bertujuan untuk mengetahui surveilans fungsi seksual pasien pascahisterektomi. Sebuah studi potong lintang melibatkan 92 pasien tumor ginekologis (jinak dan ganas) yang telah menjalani histerektomi selama minimal 3 bulan. Evaluasi disfungsi seksual menggunakan kuesioner FSFI-6, yang menilai fungsi seksual berupa sexual disorder, disfungsi seksual, gangguan hasrat(Hypoactive Sexual Desire Disorder), gangguan rangsangan(Female Sexual Arousal Disorder), gangguan orgasme(Female Orgasmic Disorder), dan nyeri (Sexual Pain Disorder). Pasien dibagi menjadi kelompok histerektomi total dan histerektomi radikal, serta dilakukan kastrasi atau tidak. Kelompok histerektomi total didapatkan sebanyak 71 pasien dan histerektomi radikal 21 pasien. Terjadi disfungsi seksual (histerektomi radikal 47,6%, histerektomi total 28,2%, kastrasi 33,8%, dan tanpa kastrasi 28,6%), gangguan orgasme(histerektomi total 28,2%, histerektomi radikal47,6%, kastrasi28,6%, tidak kastrasi 33,8%,). gangguan nyeri (histerektomi radikal 28,6% dibandingkan histerektomi total 9,9%).Akan tetapi, tidak ditemukan perbedaan secara bermakna antara fungsi seksual pasca histerektomi radikal dan histerektomi total, serta antara kelompok kastrasi dan tidak dikastrasi. Berdasarkan temuan tersebut, maka fungsi seksual menjadi penting acuan bagitenaga kesehatan dalam melakukan konseling saat sebelum dan sesudah operasi.

---

Sexual function is one component of quality of life that must be fulfilled by humans. Hysterectomy which is an operative procedure in women may cause anatomical, hormonal, and psychological changes that can cause disturbance in sexual function. This study aims to determine surveillance of sexual function after hysterectomy. This is a cross-sectional study involving 92 gynecological tumor patients (benign and malignant) who had under went a hysterectomy for at least 3 months. Evaluation of sexual dysfunction using the FSFI-6 questionnaire, which assesses sexual function in the form of sexual disorder, sexual dysfunction,desire disorders (Hypoactive Sexual Desire Disorder), stimulation (Female Sexual Arousal Disorder), orgasm disorders (Female Orgasmic Disorder), and pain (Sexual Pain Disorder).Patients were divided into totalhysterectomyand radical hysterectomy groups, and whether or not castration was performed. The total hysterectomy group had 71 patients and 21 radical patients with hysterectomy. Sexual dysfunction (radical hysterectomy 47.6%, total hysterectomy 28.2%, castration 33.8%, and no castration 28.6%), orgasmic disorders (total hysterectomy 28.2%, radical hysterectomy 47.6%, castration 28.6%, not castration 33.8%,), and pain disorder (radical hysterectomy 28.6% compared to 9.9% total hysterectomy). However, no significant differences were found between sexual function after radical hysterectomy and total hysterectomy, as well as between the castration group and notcastration.Based on these findings, sexual function is an important reference for health professionals to be considered in conducting counseling before and after surgery"

"ABSTRAKKanker serviks merupakan keganasan keempat tersering pada perempuan di dunia. Berdasarkan prognosis dan terapi, kanker serviks dibagi menjadi dua kelompok, yaitu stadium awal dan stadium lanjut. Tata laksana standar kanker serviks stadium awal adalah histerektomi radikal dan limfadenektomi. Keterlibatan kelenjar limfe merupakan salah satu faktor yang memengaruhi kesintasan pasien kanker serviks.Penelitian ini bertujuan untuk mengetahui apakah kelenjar limfe dapat dijadikan prediktor kesintasan. Penelitian ini menggunakan desain penelitian kohort retrospektif yang dilakukan di RSUPN dr. Cipto Mangunkusumo pada bulan Agustus 2015 sampai Agustus 2016.Subjek penelitian adalah pasien kanker serviks stadium awal yang dilakukan histerektomi radikal dan limfadenektomi dalam kurun waktu Januari 2011 sampai Desember 2013. Variabel yang diteliti adalah stadium tumor, ukuran tumor, histopatologi, diferensiasi tumor, invasi stroma, invasi limfovaskular, KGB pelvis, batas sayatan, dan invasi parametrium yang dihubungkan dengan kesintasan pasien. Data diolah menggunakan SPSS versi 20 dan dianalisis dengan uji chi square, uji regresi cox metode stepwise, dan Kaplan Meier. Pada penelitian ini diperoleh 123 pasien kanker serviks yang dilakukan histerektomi radikal dan limfadenektomi namun data yang dianalisis adalah 50 pasien yang memenuhi kriteri inklusi dan lolos kriteria eksklusi.Hasilnya, stadium tumor, ukuran tumor, histopatologi, diferensiasi tumor, invasi limfovaskular, KGB pelvis, batas sayatan, dan invasi parametrium tidak berhubungan dengan kesintasan namun invasi stroma dan terapi radiasi berhubungan dengan kesintasan. Jumlah KGB yang diekstraksi tidak berpengaruh terhadap kesintasan namun subjek dengan invasi stroma <2/3 bagian memiliki kesintasan lebih baik. Terapi radiasi juga memberikan kesintasan lebih baik. Perlu dilakukan penelitian lebih lanjut untuk mengetahui faktor prognostik lain pada pasien kanker serviks stadium awal seperti ekspresi faktor-faktor stem cells (SOX4, NANOG dan OCT4).

---

ABSTRACTCervical cancer is the fourth most common cancer in women in the world. Based on the prognosis and therapy, cervical cancer is divided into two groups, which are the early and advanced stages. The standard management of early-stage cervical cancer is radical hysterectomy and lymphadenectomy. The involvement of lymph nodes is one of the factors that affect the survival of cervical cancer patients.This study aims to determine whether lymph nodes can be used as predictors of survival. This study used a retrospective cohort study design conducted at RSUPN Dr. Cipto Mangunkusumo in August 2015 until August 2016.The research subjects were early-stage cervical cancer patients who performed radical hysterectomy and lymphadenectomy in the period January 2011 to December 2013. Variables studied were tumor stage, tumor size, histopathology, tumor differentiation, stromal invasion, lymph-vascular invasion, pelvic lymph nodes, incision border, and parametric invasion associated with patient survival. Data was processed using SPSS version 20 and analyzed by chi square test, cox regression test stepwise method, and Kaplan Meier. In this study 123 patients with cervical cancer were obtained for radical hysterectomy and lymphadenectomy but the data analyzed were 50 patients who fulfilled the inclusion criteria and passed the exclusion criteria.As a result, tumor stage, tumor size, histopathology, tumor differentiation, lymph-vascular invasion, pelvic lymph nodes, incision border, and parametrial invasion were not associated with survival but stromal invasion and radiation therapy were associated to survival. The number of extracted lymph node did not affect survival but subjects with stromal invasion <2/3 of parts had better survival. Radiation therapy also provides better survival. Further research is needed to find out other prognostic factors in early stage cervical cancer patients such as expression of factor stem cells (SOX4, NANOG and OCT4)."

"Tujuan penelitian ini adalah untuk mengidentifikasi faktor prediktor metastasis kelenjar getah bening (KGB) pada pasien dengan kanker serviks stadium IB dan IIA. Penelitian dilakukan dari bulan Mei 1996 sampai bulan Desember 2001. Ada 183 pasien kanker serviks dengan stadium menurut FIGO IB dan IIA menjalani operasi histerektomi radikal dan limfadenektomi. Dari pasien tersebut 158 pasien yang dapat dinilai, terdiri dari 43 pasien dengan metastasis KGB dan 115 tanpa metastasis KGB. Rancangan penelitian adalah kasus-kontrol. Kasus adalah pasien dengan metastasis KGB dan kontrol pasien tanpa metastasis KGB. Analisis multivariat dilakukan setelah analisis bivariat. Pada analisis bivariat umur < 39 tahun, diameter lesi >4 cm, stadium IIA > 4 cm, histopatologi dengan diferensiasi sedang dan buruk, invasi ke pembuluh darah dan limfa merupakan variabel yang independen terjadinya metastasis KGB dengan nilai p ≤ 0,05. Tetapi pada analisis multivariat yang muncul sebagai variabel independen adalah umur muda, paritas > 4, diameter lesi, histopatologi adenoskuamosa, dan invasi limfo-vaskular dengan nilai p ≤ 0,05. Kesimpulan: Usia muda, paritas > 4, stadium IIA > 4 cm, diameter lesi, histopatologi adenoskuamosa, invasi limfa-vaskular merupakan faktor risiko terjadinya metastasis dan dapat dipergunakan sebagai faktor prediktor metastasis KGB. (Med J Indones 2004; 13: 113-8)

---

The aim of this study was to identify possible predictor factors of lymph node metastases in patients with cervical cancer stage IB and IIA. Study was conducted between May 1996 and December 2001. There were 183 patients of cervical cancer with FIGO Stage IB and IIA who were underwent radical hysterectomy and lymphadenectomy. From those 158 patients could be evaluated, consisting 43 patients with node metastases 115 patients without metastases. Research design was case control study. Case was patients with node metastases and control was those without node metastases. Multivariate analysis was made after bivariate analysis. On bivariate analysis age < 39 years, diameter of lesion > 4 cm, stage IIA > 4 cm, histopathology moderate and poor differentiation, blood and lymphatic vessel invasion were independent variables for node metastases with p value ≤ 0.05. However, on multivariate analysis younger age, parity ≥ 4, diameter of lesion, histopathology adenosquamous, and lymph vascular invasion (+) as independent factors for node metastases with p value ≤ 0.05. Conclusion: Younger age, parity ≥ 4, stage IIA > 4 cm, diameter of lesion, histopathology adenosquamous, and lymph vascular invasion (+) were risk factors for node metastases and can be used as predictors. (Med J Indones 2004; 13: 113-8)"

"ABSTRAKTujuan: Menilai masa pemulihan disfungsi saluran kemih setelah histerektomi radikal pada pasien kanker serviks di RSUPN Ciptomangunkusumo. Metode: Studi survei dilakukan di RSUPN Cipto Mangunkusumo dari September 2016 hingga Mei 2017. Subjek penelitian terdiri dari pasien kanker serviks stadium IA2 hingga IIA2 yang menjalani histerektomi radikal. Kateter suprapubik SPC digunakan sebagai alat untuk memantau produksi urin pasca operasi. Pasien diinstruksikan untuk mengikuti protokol bladder training yaitu melalui prosedur menutup dan membuka kateter. Rasa sensasi ingin berkemih dan berkemih spontan. Pengukuran residu volume urin pasca berkemih dibawah 100mL dianggap merupakan indikator pemulihan disfungsi saluran kemih. Rata-rata hari dari setiap fase kemudian dihitung. Hasil: Dua puluh sembilan subjek didapatkan selama penelitian. Namun, hanya 21 subjek yang dapat mengikuti protocol bladder traning dan dicatat perkembangan pemulihannya. Rata-rata hari yang diperlukan untuk merasakan sensasi berkemih dan berkemih spontan adalah 7,57 4.78 hari median 5 hari, minimum 3 hari, dan maksimum 22 hari dan 8 5.21 hari. median 6 hari, minimum 3 hari dan maksimum 23 hari Rata-rata hari untuk mencapai residu urin di bawah 100 mL adalah 21.42 18 median 18 hari, minimum 7 hari, dan maksimum 74 hari . Kesimpulan: Setelah prosedur histerektomi radikal, pencatatan masa pemulihan penting untuk dipantau untuk memastikan pemulihan lengkap. Rata-rata hari yang diperlukan untuk pemulihan adalah 21.42 18 hari median 18 hari, minimum 7 hari, dan maksimum 74 hari .

---

ABSTRACTObjectives To assess the length of recovery phase in urinary tract dysfunction following radical hysterectomy for cervical cancer patients in Ciptomangunkusumo Hospital. Methods This survey study was conducted in Cipto Mangunkusumo Hospital from September 2016 to May 2017. Subjects were cervical cancer patients from stage IA2 to IIA2 underwent radical hysterectomy. Suprapubic catheter SPC was inserted to observe the urine production after procedure. Patients were then directed for bladder training protocol involving clamping and opening SPC. Sensation of bladder fullness followed by spontaneous micturition were recorded. Measurement of post voiding residual PVR urine volume after spontaneous micturition until less than 100 mL was considered as resolution of urinary tract dysfunction. The average days of every achieved phase were then calculated. Results Twenty nine subjects underwent radical hysterectomy during observation period. But only 21 subjects continued the bladder training protocol and recorded for the recovery phases. The average time needed to obtain sensation of bladder fullness and spontaneous micturition were 7.57 4.78 days median 5 days, minimum 3 days, maximum 22 days and 8 5.21 days median 6 days, minimum 3 days, maximum 23 days . The objective PVR urine became less than 100mL was obtained after 21.42 18 days median 18 days, minimum 7 days, maximum 74 days . Conslusion Following radical hysterectomy, recording the recovery phase of urinary tract dysfuction is essential to ensure complete resolution. Complete resolution of the urinary dysfunction is achieved after 21.4218 days in average median 18 days, minimum 7 days, maximum 74 days ."