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Hasil Pencarian

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Rizky Amaliah, supervisor
Karakteristik pasien ulkus peptikum perforasi dan kaitannya dengan morbiditas dan mortalitas di Rumah Sakit Cipto Mangunkusumo periode Januari 2006 - Maret 2012 = Characteristic of perforated peptic ulcer patient and correlation in morbidity and mortality in Cipto Mangunkusumo Hospital 2006 January - 2012 March
"[ABSTRAK
Ulkus peptikum perforasi merupakan salah satu kasus bedah gawat darurat yang cukup sering di RSCM. Perkembangan medikamentosa dalam tatalaksana ulkus peptikum telah berkembang pesat sehingga menurunkan angka tindakan bedah secara elektif. Studi ini bertujuan untuk melihat karakteristik dan faktor risiko pasien dengan morbiditas dan mortalitas ulkus peptikum perforasi. Seluruh pasien ulkus peptikum perforasi yang dilakukan tindakan pembedahan emergensi di Instalasi Gawat Darurat Rumah Sakit Cipto Mangunkusumo periode Januari 2006 sampai dengan Maret 2012 dievaluasi secara retrospektif. Empat puluh delapan pasien ulkus peptikum perforasi telah dilakukan tindakan pembedahan di IGD RSCM yang terdiri dari 36 pasien laki-laki dan 12 pasien perempuan dengan usia berkisar antara 17 ? 97 tahun. Faktor risiko terbanyak adalah pemakaian obat-obatan ulserogenik (NSAID dan jamu) sebanyak 70.83%. Sebanyak 52.08% pasien dengan ulkus peptikum perforasi datang dengan keluhan yang dirasakan >24 jam dengan rerata durasi 42 jam. Lokasi perforasi tersering adalah prepilorus sebanyak 66.7% dengan median diameter perforasi 10 mm. Tindakan tersering yang dilakukan adalah penjahitan primer dengan omental patch sebanyak 93.75%. Komplikasi tersering adalah acute kidney injury, sepsis dan infeksi luka operasi sebanyak 45.83%, 31.25% dan 14.58%. Angka morbiditas dan mortalitas pasien ulkus peptikum perforasi adalah 68.75% dan 33.3%. Pada studi ini tidak ditemukan hubungan yang bermakna antara karakteristik pasien dengan morbiditas dan mortalitas. Angka morbiditas dan mortalitas pasien ulkus peptikum perforasi masih tinggi. Faktor risiko yang ada dapat digunakan untuk meningkatkan pilihan tindakan dan menurunkan morbiditas dan mortalitas pasien ulkus peptikum perforasi. ABSTRACT Perforated peptic ulcer is one of the most common emergency case in RSCM. Development medicine treatment in peptic ulcer treatment had developed hence had decreased number of elective surgical treatment. This study was aimed to identify patients? characteristic and risk factor in perforated peptic ulcer in morbidity and mortality. All of the patient of perforated peptic ulcer that was done emergency laparotomy in emergency operating room of Cipto Mangunkusumo Hospital since 2006 January until 2012 March was evaluated retrospectively. Fourty eight percent of perforated peptic ulcer patients had been done surgery in Emergency Operating Room of Cipto Mangunkusumo Hospital that consist of 36 male and 12 female with age range 17 ? 97 years old. The most common risk factor is ulcerogenic drug using (70.83%). Patients came to hospital >24 hours (52.08%) after felt complaint with mean duration 42 hours. The most common location of perforation was prepiloric with median of diameter was 10 mm. The most common surgical treatment was primary suturing with omental patch (93.75%). The common complication were acute kidney injury, sepsis and surgical wound infection around 45.83%, 31.25% and 14.58%/. Morbidity rate was 68.75%. Mortality rate was 33.3%. There were no relation between patients? characteristic with morbidity and mortality. Morbidity and mortality rate in perforated peptic ulcer were still high. Risk factor that still be used to increase more choice for surgical treatment and decrease morbidity and mortality rate in perforated peptic ulcer., Perforated peptic ulcer is one of the most common emergency case in RSCM. Development medicine treatment in peptic ulcer treatment had developed hence had decreased number of elective surgical treatment. This study was aimed to identify patients’ characteristic and risk factor in perforated peptic ulcer in morbidity and mortality. All of the patient of perforated peptic ulcer that was done emergency laparotomy in emergency operating room of Cipto Mangunkusumo Hospital since 2006 January until 2012 March was evaluated retrospectively. Fourty eight percent of perforated peptic ulcer patients had been done surgery in Emergency Operating Room of Cipto Mangunkusumo Hospital that consist of 36 male and 12 female with age range 17 – 97 years old. The most common risk factor is ulcerogenic drug using (70.83%). Patients came to hospital >24 hours (52.08%) after felt complaint with mean duration 42 hours. The most common location of perforation was prepiloric with median of diameter was 10 mm. The most common surgical treatment was primary suturing with omental patch (93.75%). The common complication were acute kidney injury, sepsis and surgical wound infection around 45.83%, 31.25% and 14.58%/. Morbidity rate was 68.75%. Mortality rate was 33.3%. There were no relation between patients’ characteristic with morbidity and mortality. Morbidity and mortality rate in perforated peptic ulcer were still high. Risk factor that still be used to increase more choice for surgical treatment and decrease morbidity and mortality rate in perforated peptic ulcer.]"
Fakultas Kedokteran Universitas Indonesia, 2013
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UI - Tugas Akhir  Universitas Indonesia Library
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Eko Ristiyanto
Stres Psikologis Sebagai Faktor Risiko Tukak Peptikum Perforasi di Masa Pandemi COVID-19 = Psychological Stress as a Risk Factor for Perforated Peptic Ulcers during the COVID-19 Pandemic
"Latar Belakang: Peningkatan insiden tukak peptikum perforasi (TPP) Divisi Bedah digestif RSUPN Dr. Cipto Mangunkusumo Jakarta. Selama enam bulan awal pandemi Covid-19, naik empat kali lipat, dibandingkan enam bulan sebelum pandemi Covid-19. Penelitian ini bertujuan untuk menilai peran stres psikologis sebagai faktor risiko tukak peptikum perforasi.
Metodologi: Merupakan studi retrospektif potong lintang, membandingkan 2 kelompok subjek penelitian, TPP pandemi Covid-19 Maret 2020 hingga Maret 2021 dan non-pandemi Covid-19 Juli 2017 hingga Februari 2020. Data demografi, klinis, dan tingkat stres psikologis yang diukur dengan Perceived Stress Scale (PSS-10) merupakan variabel yang diperiksa.
Hasil: Tercatat 53 TPP, 28 subjek pada pandemi, pria 11, wanita 17, rerata usia 63 tahun, pemakaian obat antiinflamasi nonsteroid atau jamu 80%, komorbid 92,8%, lama rawat 23,6 hari, morbiditas 78,5%, infeksi daerah operasi 17%, pneumonia 38,9%, dan mortalitas 46,4%. 25 subjek pada non-pandemi, pria 21, wanita 4, rerata usia 53 tahun, penggunaan obat antiinflamasi nonsteroid atau jamu 85%, komorbid 48%, rerata skor boey 1,3, PULP 6,8, ASA 3, lama rawat 16,2 hari, morbiditas 52%, infeksi daerah operasi 12%, pneumonia 36%, dan mortalitas 28%. Penilaian PSS-10 pada 37 subjek, pada pandemi, stres berat delapan, stres sedang tujuh, stres ringan empat. Pada non-pandemi stres berat satu, stres sedang delapan, stres ringan sembilan. Uji Fischer exact didapatkan perbedaan antara stres ringan-sedang dengan stres berat pada kedua kelompok, p = 0,019. Uji Spearman didapatkan korelasi moderat (rs = 0,422) antara stres psikologis dengan pandemi, p = 0,009.
Simpulan: Pandemi Covid-19 memperberat stres psikologis, meningkatkan morbiditas dan mortalitas tukak peptikum perforasi.
Background: Increased incidence of perforated peptic ulcer (PPU) Digestive Surgery Division, Dr. Cipto Mangunkusumo Hospital, Jakarta. During early of six months Covid-19 pandemic, increased four times, compared to six months before Covid-19 pandemic. This study aims to evaluate the role of psychological stress as a risk factor for perforated peptic ulcer.
Methodology: a cross-sectional retrospective study, compare 2 groups on the PPU subjects of COVID-19 pandemic March 2020 to March 2021 and non-pandemic Covid-19 July 2017 to February 2020. Demographic, clinical, and psychological stress data as measured by Perceived Stress Scale (PSS-10) were variables to be evaluated.
Results: Registered 53 PPU, 28 subjects in Covid-19 pandemic, 11 males, 17 females, 63 years mean age, 80% used of nonsteroidal anti-inflammatory drugs or Indonesian herbs, 92.8% comorbidities, 23.6 days length of stay, 78,5% morbidity, 17% surgical site infection, 38.9% pneumonia, and 46,4% mortality. 25 subjects in non-pandemic, 21 males, 4 females, 53 years mean age, 85% non-steroidal anti-inflammatory drugs or Indonesian herbs, 48% comorbidity, 1.3 mean boey score, 6.8 PULP, 3 ASA, 16.2 days length of stay, 52% morbidity, 12% surgical site infection, 36% pneumonia, and 28% mortality. PSS-10 evaluated on 37 subjects, in pandemic, eight severe stress, seven moderate stress, four mild stress. In non-pandemic, one severe stress, eight moderate stress, and nine mild stress. Fischer's exact test found a difference between mild-moderate stress and severe stress in both groups, p = 0.019. Spearman's test found a moderate correlation (rs=0.422) between psychological stress and the pandemic, p = 0.009.
Conclusion: Covid-19 pandemic exacerbates psychological stress, increasing morbidity and mortality of perforated peptic ulcer."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2021
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library