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Abstrak :
Kadar C-reactive protein (CRP) dalam plasma di laporkan meningkat pada individu obes.

Abstrak :
Kadar C-reactive protein (CRP) dalam plasma dilaporkan meningkat pada individu obes. Pada penelitian ini. akan dievaluasi korelasi antara hsCRP dan massa ventrikel kin. Empat puluh lima wanita obes sehat dan empat puluh lima wanita non obes sehat sebagai kontrol dilakukan evaluasi ekokardiografi dan pengukuran kadar hsCRP. Tidak lerdapat korelasi antara hsCRP dan massa venlrikel kiri pada wanita obes (r=0,29, p 0,06). Terdapat korelasi bermakna antara hsCRP dan indeks massa tubuh= 0.46, p 0,002), dan juga hsCRP dan ketebalan lemak viseral (r= 0.33, p 0.03). (Med J Indones 2006; 15:100-4)

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Plasma C-reactive protein (CRP) concentrations are increased in obese individuals, in this study, we examined the correlation between hsCRP and left ventricular mass (LV mass). Fourtyfive healthy obese women and fourty five healthy non obese women as the controls group were studied by echocardiography and hsCRP. There was no significant correlation between hsCRP and left ventricular mass in obese women (r=0,29, p 0,06). There was a significant correlation between hs CRP and body mass index fr= 0.46, p 0,002), and also hsCRP and visceral fat (r= 0.33, p 0.03). (Med J Indones 2006; 15:100-4)

Abstrak :
Tujuan : Mengetahui pengaruh diet rendah kalori seimbang terhadap resting energy expenditure (REE), respiratory quotient (RQ) dan profil lipid serum untuk menurunkan morbiditas dan mortalitas penderita obesitas. Tempat : Rumah Sakit Sumber Waras Jakarta Bahan dan cara : Penelitian merupakan suatu eksperimental pra dan pasca pemberian diet rendah kalori seimbang 1000 Kkal dengan komposisi 55 % karbohidrat, 20 % protein dan 25 % lemak selama 14 hari terhadap 38 subjek perempuan obes (19-55 tahun) yang telah memenuhi kriteria penerimaan dan penolakan. Data yang dikumpulkan meliputi data karakteristik sosial demografi, data asupan energi dan makronutrien, antropometri, REE, RQ, kadar kolesterol total, trigliserida, kolesterol LDL dan kolesterol HDL serum. Hasil : Setelah pemberian diet 1000 kkal selama 14 hari pada perempuan obes terjadi penurunan bermakna dari berat badan sebesar 2,64% (p= 0,001), penurunan IMT 2,77% (p= 0,001), penurunan persentase massa lemak tubuh 1,44% (p= 0,001), peningkatan persentase massa bebas lemak 1,36% (p= 0,001), penurunan rasio Lpi-Lpa 2,5% (p= 0,001), penurunan tidak bermakna dari REE 4,41% (p= 0,071), penurunan bermakna dari RQ 4,78% (p= 0,036), penurunan kolesterol total 6,67% (p= 0,001), penurunan trigliserida 22,92% (p= 0,001), penurunan kolesterol LDL 4,22% (p 0,027) dan penurunan kolesterol HDL serum 5,54% (p= 0,004). Simpulan : Pemberian diet rendah kalori seimbang sebesar 1000 Kkal/hari selama 14 hari terbukti dapat menurunkan secara bermakna berat badan, IMT, persentase massa lemak, meningkatkan persentase massa bebas lemak, menurunkan rasio Lpi-Lpa, RQ, kolesterol total, trigliserida, kolesterol LDL dan kolesterol HDL serum, tetapi tidak menurunkan secara bermakna REE pada perempuan obes.

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Objective : To identify the effect of balanced low calorie diet on REE, RQ and serum lipid profile of obese women in reducing morbidity and modality of obese people. Place : Sumber Waras Hospital, Jakarta. Materials and Methods : The study was an experimental, pre and post balanced low calorie diet (1000 Kcals/day, 55% carbohydrate, 20% protein and 25% fat) for 14 days. Thirty eight obese women, 19.-55 years old had been selected as subjects according to inclusion and exclusion criteria The data that had been collected were social and demographic characteristics, the energy and macronutrient intake, anthropometric, REE, RQ, level of total serum cholesterol, triglyceride, LDL cholesterol and HDL cholesterol. Results : After 14 days balanced low calorie diet , there were significant reduction of body weight 2,64% (p= 0,001), body mass index 2,77% (p= 0,001), percentage of fat mass 1,44% (p= 0,001), increarnent percentage of fat free mass 1,36% (p= 0,001), reduction of waist to hip ratio 2,5% (p= 0,001), insignificant reduction of REE 4,41% (p= 0,071), significant reduction of RQ 4,78% (p= 0,036), level of total serum cholesterol 6,67% (p= 0,001), triglyceride 22,92% (p= 0,001), LDL cholesterol 4,22% (p= 0,027) and HDL cholesterol 5,54% (p= 0,004). Conclusion : Balanced low calorie diet was had been shown to reduce body weight, body mass index, percentage of fat mass, to increase percentage of fat free mass, to reduce waist to hip ratio, RQ, level of total serum cholesterol, triglyceride, LDL cholesterol and HDL cholesterol of obese women significantly, but didn't reduce REE significantly.

Abstrak :
Tujuan : Mengetahui pengaruh pemberian diet rendah kalori seimbang selama 14 hari terhadap berat badan (BB), indeks massa tubuh (IMT), tebal lipatan kulit total. (TLK), massa lemak tubuh (ML), massa tubuh bebas lemak (MBL), rasio lingkar pinggang-lingkar panggul (R Lpi-Lpa) , dan kadar leptin serum. Tempat : Rumah Sakit Sumba Waras, Grogol Bahan dan cara: Penelitian ini merupakan studi eksperimentai pra dan pasca pemberian diet rendah kalori seimbang 915,23 kkal dengan komposisi 55,81% karbohidrat, 19,46% protein dan 24,73% lemak selama 14 hari terhadap 39 subyek perempuan obes (19-55 tahun) yang telah memenuhi kriteria penerimaan dan penolakan. Data yang dikumpulkan meliputi data karateristik demografi, data asupan energi dan makronutrien, antropornetri, komposisi tubuh, dan kadar leptin serum. Hasil : Terjadi penurunan berat badan secara bermakna (p<0,05) dari 70,99 ± 8,62 menjadi 68,81 ± 8,36 kg (3,07%); penurunan IMT secara bermakna (p<0,05) dari 30,20 ± 3,11 kg/m2 menjadi 29,36 ± 2,94 kg/m2 ( 3,04%); penurunan TLK secara bermakna (p<0,05) dari 99,32 ± 12,07 mm menjadi 91,29 f 10,85 mm (8,08%); penurunan ML secara bermakna (p<0,05) dari 35,41 ± 2,75 % menjadi 33,65 ± 2,73% (1,76 %) peningkatan persentase MBL secara bermakna. (p<0,O5) dari 64,59 2,74 menjadi 66,35 2,73% (2,72%);penurunan Lpi secara bermakna (p<0,O5) dari 85,87 7,31 menjadi 83,35 ± 7,09 cm (2,93%); penurunan Lpa secara bermakna (p<0,05) Bari 107,59 ± 6,67 menjadi 106,49 f 6,37 cm (1,02%); penurunan R Lpi-Lpa secara bermakna (p(O,O5) dari 0,80 ± 0,05 menjadi 0,78 ± 0,04 (2,24 %); penurunan kadar leptin serum secara bermalma (p<0,05) dari 23,31 (12,06-71,22) menjadi 18,18 (7,90-65,11) pg/mL (22,01 %); ditemukan korelasi positif antara kadar leptin serum dengan ML secara bermakna (p<0,05) sebelum perlakuan 0=0,47 ; p t,003) dan sesudah perlakuan (r3,57 ; p=0,001). Simpulan : Pemberian diet rendah kalori seimbang sebesar 915,23 kkal/h selama 14 hari dapat dengan efektif menurunkan berat badan, IMT, tebal lemak bawah kulit, persentase lemak, meningkatkan persentase massa bebas lemak, menurunkan rasio lingkar pinggang lingkar panggul dan kadar leptin serum, serta ditemukan korelasi positif bermakna antara massa lemak tubuh dan leptin serum baik sebelum maupun sesudah perlakuan.

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Objective : To identify the effect of balanced low-calorie diet for 14 days on body weight (BW), body mass index (BMI), total skin fold thickness (SFT), fat mass (FM), fat-free mass (FFM), waist to hip ratio (WHR) and serum leptin level. Place : Sumber Waras Hospital, Grogol Material and Method : This study is a pre- and post-experimental balanced low-calorie diet 915.23 kcallday with the composition of 55.81 % carbohydrate, 19.46 % protein and 24.73 % fat for 14 days on 39 obese-women subjects (19-55 years old) who have met the inclusion and exclusion criteria. The collected data include demographic characteristic, macronutrient and energy intake, as well as of anthropometry, FM, FFM, and serum leptin level. Results : Body weight reduction occurs significantly (p<0.05) from 70.99 ± 8.62 to 68.81 ± 8.36 kg (3,07%), BMI reduction is significant (p<0.45) from 30,20 + 3,11kglm2 to 29,36 ± 2,94 kghn' (3,04%); significantly reduced SFT (p<0.05) from 99,32 ± 12,07 mm to 91,29 ± 10,85 mm (8,08%); significantly reduced FM (p<0,05) from 35.41 ± 2.75% to 33.65 ± 2.73% (1.76%); significantly increased FFM percentage (P<0.05) from 64.59 ± 2.74 to 66.35 ± 2.73 (2.72%); significantly reduced WC (waist circumference) (p<0.05) from 85.87 ± 7.31 to 83.35 ± 7.09 (2.93%); significantly reduced HC (hip circumference) (p<0.05) from 107.59 ± 6.67 to 106.49 ± 6.37 (1.02%); significantly reduced WHR (p<0.05) from 0.80 ± 0.05 to 0.78 ± 0.04 (2.24%); significantly reduced serum leptin level (p<0.05) from 23.31 (12.06 - 71.22) to 18.18 (7.90 - 65.11) (22.01%); positive correlation is observed between serum leptin level and FM significantly (p<0,05) before treatment (r= 0.47; p = 0.003) and after treatment (r=0,57; Conclusions : Balanced low-calorie diet may effectively reduce body weight, BMI, skin fold thickness, percentage of fat mass, to increase percentage of fat free mass, to reduce waist to hip ratio and serum leptin level. There is a statistically significant positive correlation between serum leptin and body fat mass both before and after treatment.

Abstrak :
ABSTRAK Ruang lingkup dan cara penelitian : Telah dilakukan penelitian eksperimental terhadap 30 orang karyawati RSPP dengan IMT 25,2 -- 31,0. Penelitian bertujuan untuk melihat pengaruh pemberian Psyllium Hydrophillic Mucilloid ( PHM ) terhadap penurunan berat badan . Subyek dibagi menjadi dua kelompok secara acak sederhana . Kelompok I diberi diet rendah kalori seimbang, latihan fisis dan PHM. Kelompok lainnya diberi diet dan latihan fisis saja. Lama penelitian selama 8 minggu.Diet yang diberikan 500 - 1000 kalori di bawah kebutuhan kalori, dengan komposisi 12-15 % protein,20 - 30 % lemak, 55 - 68 % karbohidrat. PHM diberikan 2 x 3,5 g / hari, dilarutkan dalam 200 ml air, diminum 30 menit sebelum makan. Latihan fisis diberikan 4 x / minggu berupa jalan kaki selama 1,5 jam. Hasil dan kesimpulan : Terdapat penurunan berat badan + 3,44 kg pada kelompok serat dan + 2,93 kg pada kelompok non serat. Pengukuran lapisan lemak menunjukkan adanya penurunan sebesar + 0,97 % pada kelompok serat dan + 1,01 % pada kelompok non serat. Juga terjadi penurunan kolesterol total + 14,00 mg/dl dan + 12,33 mg/dl, trigliserida + 10,93 mg/dl dan + 8mg/dl, kolesterol LDL + 19,00 mg/dl dan 18,47 mg/di dan kenaikan kolesterol HDL + 6,2 mg/dl dan + 7,3 mg/dl pada kelompok serat dan non serat. Uji statistik menunjukkan tidak ada perbedaan antara keduanya. Tidak terdapat perubahan kadar Hb. Terdapat perbedaan dalam rasa lapar dan asupan makanan, tetapi secara statistik tidak bermakna. Kesimpulan : pemberian PHM belum dapat mengurangi rasa lapar dan belum dapat menurunkan asupan kalori, belum dapat menurunkan berat badan dan lemak tubuh secara bermakna, belum dapat memberikan perubahan pada profit lipid secara bermakna.

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ABSTRACT Effect Of Psyllium Hydrophillic Mucilloid On Weight Loss In Overweight Female Workers In Pertamina Central HospitalScope and Method of Study : An experimental study was carried out in 30 healthy female workers from Pertamina Central Hospital Jakarta, during 8 weeks. The study was carried out, therefore, to investigate the effectiveness of a hydrophillic mucilage preparation in the treatment of obesity. Subject aged between 34 and 46 years and their BMI between 25.20 and 31.02 . The subjects were randomly divided into two groups. Group I received diet plus Psyllium Hydrophillic Mucilloid ( PHM ) and exercise. Group II received only diet and exercise. PHM was administered 3.5 g , twice daily, 30 minutes before meals, diluted in 200 ml water. The diet should furnish 500 -1000 kcal/ day less than maintenance requirement comprising ofprotein 0.8 to 1.2 g / kg body weight c.q.12 to 15 % of total kcal, fat 20 to 30% , 55 - 68 %carbohydrate respectively and 15 to 25 fiber/1000 kcal. Exercise was carried out 4 times / week, with1.5 hours duration of brisk walking. Weight and heart rate was recorded. Program was evaluated with anthropometry measurement,determination of hemoglobin & lipid profile. Findings and Conclusions : Group I showed a mean body weight decrease of + 3.4 kg while group II yielded a mean body weight decrease of only + 2.9 kg. The difference in body weight variations was not statistically significant. The body fat decrease of + 0.97 on group I and + 1.01 % on group II. No significant difference in total body fat reduction between the two groups studied. The mean plasma cholesterol values in group I was de - creased to + 14 mg / dl, while in group II + 12 mg/ dl . There was no significant difference between the two groups.Treatment with diet plus PHM caused a decrease mean plasma triglyceride of + 11 mg/dl and in the second group, there was a decrease of 8 mg / dl. The difference between the 'two groups were not statistically signifi cant . No change in appetite was reported by 66.7 % subjects group I and 33.3 % from group II . Moderate hungry was reported by 33.3% subjects group I and 53.3 % subjects group II. Severe hungry was reported by 13.3 % subjects group II. There was no significant difference in caloric intake.