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Abstrak :
Indonesian Journal of Dentistry 2006; Edisi Khusus KPPIKG XIV: 22-24 Lichen planus is relatively common inflamatory disorder which may have cutaneous and/or mucosal manifestation. The maglinant potential of oral lichen planus is still debatable. Some authors are sceptical about the premaglinant nature of the disease, while other investigators have reporterd that maglinant transformation occur in 1-10% of the cases. The aim of this study is to report a case of erosive oral lichen planus which shows maglinant transformation on histopatologic examination. A man of 39 years old visited the Dental Departement of Kariadi's Hospital with pain symptom of palatum, buccal and gingival mucosa both side for 6 months. On the physical examination shows the white lesions with striae configuration and pain, red erosive area inside on the palatum extends to the buccal mucosa and the gingival. The suspect dignose is erosive lichen planus, but the histopathologic examination shows epidermoid carcinoma. lt is concluded that erosive oral lichen planus has the potential to transform into epidermoid carcinoma.

Abstrak :
Oral lichen planus (OLP) is a rather common oral disease, mainly affecting adults, occurring more often in women than in men. The etiopathogenesis is still unclear. The diagnosis may be cumbersome, even in the presence of a biopsy. In addition, there are several lesions that may resemble lichen planus (lichenoid lesions) both clinically and histopathologically. Treatment of OLP can only be symptomatic and usually consists of topical application of corticosteroids. The disease is characterized by remissions and exacerbations and may persist in some patients lifelong. There is an ongoing debate in the literature as whether OLP is a potentially malignant disease. Because of this uncertainty, annual follow-up is advised.

Abstrak :
ABSTRAK Penelitian mengenai lichen dilakukan di lingkungan kampus Universitas Indonesia, Depok pada Agustus 2015 -- Januari 2016. Tujuan dari penelitian ini adalah untuk menentukan struktur komunitas lichen di Universitas Indonesia, Depok. Tujuh plot 25 x 25 m dibuat di hutan kota dan sembilan garis transek masing-masing sepanjang 50 m dibuat di jalan utama kampus. Lima pohon dipilih pada setiap titik plot dan transek garis sebagai sampel. Sampel diambil dari pohon dengan DBH (Diameter at Breast Height) minimal 20 cm dengan jaring plastik 10 cm x 10 cm yang melekat di utara, selatan, timur, dan barat sisi batang pohon. Jaring plastik dibagi menjadi 100 kotak persegi, kemudian ditempel pada pohon dengan ketinggian yang berbeda (0 cm -- 100 cm dan 100 cm -- 200 cm) dari permukaan tanah. Hasilnya diperoleh tiga famili lichen yang ditemukan di hutan kota yaitu, Leprariaceae, Sarrameanaceae dan Physciaceae dan lima famili lichen di jalan utama kampus yaitu, Sarrameanaceae, Parmeliaceae, Leprariaceae, Graphidaceae dan Physciaceae. Kesamaan famili lichen antara hutan kota dan jalan utama kampus berdasarkan Indeks Sorenson sebesar 75%. Famili Leprariaceae adalah famili yang dominan di hutan kota, sementara Sarrameanaceae adalah famili yang dominan di jalan utama kampus. Keragaman lichen kedua lokasi dikategorikan sedang berdasarkan Indeks Shannon Wiener (H '1--3), namun tidak ada yang berbeda secara signifikan di antara kedua tempat tersebut. Famili Leprariaceae memiliki frekuensi kehadiran tertinggi pada pohon inang yaitu pohon daruak (Microcos tomentosa) sebesar 7,5%. Berdasarkan uji asosiasi (x2) antara tekstur kulit pohon dengan lichen menunjukkan asosiasi positif antara tekstur kulit pohon dengan lichen. Kehadiran famili Sarrameanaceae, Leprariaceae, Graphidaceae dan Physciaceae dipengaruhi oleh tekstur kulit pohon inang sedikit kasar.

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ABSTRACT Research on lichens was conducted at the Universitas Indonesia, Depok on August 2015 -- January 2016. The aim of this research is to determine community structur of lichen at the Universitas Indonesia, Depok. Seven plots of 25 x 25 m2 were made at the urban forest, while nine of 50 m line transect were made at the main road. Five trees of each plots and line transect were sampled. The samples were taken from trees with DBH (Diameter at Breast Height) minimum 20 cm then the grid 10 cm x 10 cm were attached at northern, southern, eastern, and western site of the trunk. The grid was divided into 100 square, then attached on trees in different height (0 cm - 100 cm and 100 cm - 200 cm) from the land surface. The result obtained three family of lichens were found in urban forest, they are Leprariaceae, Sarrameanaceae and Physciaceae. Five family were found at the main road, they were Sarrameanaceae, Parmeliaceae, Leprariaceae, Graphidaceae and Physciaceae. The similarity of lichens family between the urban forest and main road based on Sorenson similarity were high 75%. Family Leprariaceae was the dominant family at the urban forest, while Sarrameanaceae was dominant family at the main road. The diversity of lichen at both sites were categorized medium based on Shannon Wiener index (H? 1--3), however there was not significantly different between those place. Family Leprariaceae was the highest frequency of present on daruak (Microcos tomentosa) host tree, that was 7,5%. Based association test (x2) between the texture of tree bark with lichen, shows that positive association between the texture of tree bark with lichen,the presence of Sarrameanaceae, Leprariaceae, Graphidaceae and Physciaceae family is influenced by bark slightly rough.

Abstrak :
Serbuk kering talus lichen Ramalina Javanica Nyi, yang dikumpulkan dari Kebun Raya Nasional Cibodas, Jawa Barat, pertama-tama diekstraksi sinambung dengan n-heksana menggunakan soklet. Ekstraks dari hasil ekstraksi pertama kemudian dipisahkan melalui kromatografi kolom menggunakan campuran n-heksana : chloroform = 1 : I (v/v). Dan pemisahan ini dapat diisolasi 90 mg kristal murni jingga dengan titik leleh 203°C (Senyawa A). Ampas kering dari ekstraksi pertama itu, kemudian melalui cara yang sama, diekstraksi lebih lanjut dengan aseton. Hasilnya kemudian dipisahkan melalui kromatografi lapis tipis preparatif (sebagai fasa mobil: campuran n-heksana : etil asetat = 3:2). Dan pemisahan ini dapat dihasillcan 27 mg serbuk kuning dengan titik leleh = 153°C (Senyawa B). Berdasarkan pada sifat fisik (titik leleh dan putaran optis) dan data perbandingan spektroskopi dapat ditentukan struktur dua senyawa yang diisolasi itu. Senyawa A dikenal sebagai parietin (C16 H12 Os). Sementara senyawa B merupakan suatu senyawa baru golongan antrakuinon Dari jenis jenis senyawa yang diketemukan di dalam lichen. Kerangka dasarnya mirip parietin, tetapi rantai sampingnya lebih panjang daripada gugus yang terdapat pada parietin, dengan satu pusat asimetrik pada C-1?. Oleh karena itu diusulkan senyawa B sebagai R- (+}- 1,8- dihidroksi -3- (1'- hidroksi -3'-butanoil) -6-metoksi antrakuinon (C19 H16 O7). Dari hasil uji pendahuluan aktivitas antibakteri dengan menggunakan metoda Konsentrasi Hambatan Minimum (KHM) dan metoda difusi agar terhadap Staphylococcus aureus dan Escherichia coli, menunjukkan bahwa ekstraks dari fraksi n-heksana dan aseton mempunyai aktivitas yang rendah dibandingkan dengan antibiotik ampisilin (memberikan hasil negatif).

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The dried powder of thallus lichen Ramalina Javanica Nyl_ which collected from the National Botanical Garden, Cibodas, West Java, first continuously extracted with n-heksane by using sohxlet apparatus. The raw extract from the first extraction was then separated over coloumn chromatography by using mixture of n-heksane : chloroform = 1: 1 (vlv) as eluent. From this separation can be isolated 90 mg pure orange crystal with melting point = 203°C (Compound A). The dried residu from the first extraction, was then by same way, continuously extracted with acetone. The resulted extract was then separated over preparative thin layer chromatography (mixture of n-heksane : ethyl acetate = 3 : 2 as mobile phase). From this separation can be yielded 27 mg yellow powder with melting point = 253°C (Compound B). Based on the physical properties (melting point and optical rotation), spectroscophical and comperative data can be elucidated the structure both isolated compounds. Compound A was identified as (C16H12O5), meanwhile compound B was proposed as new compound at the anthraquinone's class of the lichen constituent types. Its base skeleton likes parietin, but its side chain is longer than side chain of parietin, with one assyrnetric center at the C-1'. Therefore it is proposed that compound B as R- (+) -1,8-dihidroxy -3- (1' -hidroxy -3' -butanoyl) -6-methoxy anthraquinone (C 19H16 O7). The result of antibacterial activity pretest using concentration minimum inhibition and gel diffuse method against Staphylococcus aureus and Escherichia coli showed that raw extract from n-heksane and acetone fraction has low activity compared with amphicylin antibiotic (given negative result).