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Excessive hepatocyte apoptosis induced by bile acid accumulation occurred in severe obstructive jaundice, and impair the liver secretion function. The objective of this study is to determine whether the inhibition of bile acid accumulation through bile duct decompression affect the excessive hepatocyte apoptosis and caused improvement the liver secretion functions on human model. In this study we use a before and after study on severe obstructive jaundice patients due to extra hepatic bile duct tumor ...
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[Direktorat Riset dan Pengabdian Masyarakat UI ; Fakultas Kedokteran Universitas Indonesia, Fakultas Kedokteran Universitas Indonesia], 2011
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