Hasil Pencarian  ::  Simpan CSV :: Kembali

"In up to 80% of dyspepsia patients who consult a physician in the hospital, dyspepsia is considered to be functional dyspepsia. Although not associated with increased mortality, functional dyspepsia is a burden at both the community and national levels because it can cause physical, mental, and social ditress that can affect a patients quality of life. Health-related quality of life (HRQOL) is a multidimensional construct comprising at least three broad domains-physical, psychological, and social functioning-which can all be affected by a disease and its treatment. It is important to assess HRQOL in patients with functional dyspepsia to identify the effects of the disease and its treatment on patients. Both disease-specific and generic instruments can be used to assess HRQOL in patients with functional dyspepsia. Each instrument has it own advantages and limitations. The selection of instrument to assess HRQOL is determined by the study population, research questions, disease entities, and researcher preferences. The purpose of this article is to explain the concept of HRQOL and the use of HRQOL assessment in patients with functional dyspepsia."

"Pendahuluan : Adolescent Idiopathic Scoliosis (AIS) adalah jenis skoliosis yang paling umum terjadi pada populasi pediatrik, mencakup 80% dari total kasus, dan seringkali mengakibatkan morbiditas serta hendaya kepada penderitanya. Parameter evaluasi Health Related Quality of Life (HRQL) menjadi penting karena AIS mempengaruhi kondisi klinis, sosial, dan psikologis penderitanya. Salah satu kuesioner evaluasi HRQL yang populer adalah Short Form-36 (SF-36), yang bersifat general dan telah diadaptasikan ke bahasa Indonesia. Namun, kuesioner ini tidak spesifik untuk skoliosis. Scoliosis Research Society (SRS) telah mengembangkan kuesioner HRQL spesifik untuk skoliosis, yaitu SRS-22r, yang terdiri dari 5 domain penilaian. Kuesioner ini telah diadaptasi ke berbagai bahasa, tetapi belum ada versi berbahasa Indonesia yang terdaftar di SRS. Oleh karena itu, peneliti berupaya melakukan adaptasi lintas budaya kuesioner SRS-22r agar dapat diaplikasikan pada praktik klinis di Indonesia.Metode : Penelitian ini merupakan studi potong lintang untuk adaptasi lintas budaya, uji validitas dan reliabilitas kuesioner SRS-22r berbahasa Indonesia (SRS-22r INA) pada pasien dengan Adolescence Idiopathic Scoliosis. Penelitian ini menggunakan metode consecutive sampling hingga terpenuhinya kuota sampel, berdasarkan perhitungan besar sampel untuk adaptasi kuesioner menggunakan sampel minimal untuk uji pra final, uji validitas dan uji reliabilitas.Hasil : Terdapat 50 responden perempuan (75.8%) dan 16 responden laki-laki (24.2%). Kurva utama yang paling umum adalah thorasic (75.8%), sedangkan yang paling jarang ditemukan adalah thoracolumbar (3.0%). Sebanyak 69.7% responden dikategorikan sebagai skoliosis dengan sudut berat (Cobb angle >450). Nilai rerata kurva utama adalah 57.33, dengan nilai minimum 10.7 dan maksimum 100.2. Standar deviasi yang relatif tinggi (22.73) menunjukkan besarnya variabilitas data. Kelima domain kuesioner SRS- 22r INA tidak terkena floor effect dan ceiling effect lebih dari 15%. Uji validitas konstruksi menunjukkan bahwa domain SRS-22r INA memiliki korelasi yang tinggi dengan domain SF-36 INA. Hasil Chronbach’s alpha menunjukkan bahwa butir pertanyaan pada domain SRS-22r INA sangat reliabel.Kesimpulan : Berdasarkan hasil adaptasi lintas budaya, uji validitas dan uji reliabilitas kuesioner, SRS-22r INA merupakan kuesioner yang valid dan reliabel. Kuesioner ini dapat digunakan sebagai parameter HRQL untuk evaluasi penderita AIS di Indonesia.

---

Introduction : Adolescent Idiopathic Scoliosis (AIS) is the predominant form of scoliosis observed in the pediatric patient, constituting approximately 80% of all reported cases, this condition frequently leads to adverse health outcomes and functional impairments among affected patient. The assessment of Health Related Quality of Life (HRQL) is paramount due to the impact of AIS on the clinical, social, and psychological aspects of affected patient. The Short Form-36 (SF-36) is a widely used questionnaire for evaluating HRQL. It is a comprehensive tool that has been developed for use in various populations, including the Indonesian population. Nevertheless, this questionnaire lacks specificity in relation to scoliosis. The Scoliosis Research Society (SRS) has devised a dedicated HRQL survey for scoliosis, known as the SRS-22r. This questionnaire encompasses five distinct domains for evaluation. The present questionnaire has been modified and translated into other languages; nevertheless, it is worth noting that an Indonesian version is not yet included in the SRS. This study aims to conduct a cross-cultural adaptation of the SRS- 22r questionnaire to facilitate its implementation in therapeutic settings within Indonesia. Method : This study aims to achieve cultural adaptation, validity and reliability evaluation of the SRS-22r INA questionnaire in patients with Adolescence Idiopathic Scoliosis through a cross-sectional design. The present study employs the consecutive sampling technique to achieve the desired sample size, as determined by sample size calculations. The questionnaire is adapted through a preliminary testing phase followed by validity and reliability test. In addition, inclusion and exclusion criteria are established to choose participants for the study.

Result : There were 50 female respondents (75.8%) and 16 male respondents (24.2%). The most common main curve was thoracic (75.8%), while the least common was thoracolumbar (3.0%). A total of 69.7% of respondents were categorized as scoliosis with a severe angle. The average value of the main curve was 57.33, with a minimum value of 10.70 and a maximum value of 100.20. A relatively high standard deviation (22.73) indicates the amount of data variability. The five domains of the SRS-22r INA questionnaire were not affected by the floor effect and ceiling effect of more than 15%. The construct validity test showed that the SRS-22r INA domain had high correlation with the SF-36 INA domain. Chronbach’s alpha results showed that the question items in the SRS-22r INA domain were highly reliable.

Conclusion : Based cross cultural adaptation, validity testing and reliability testing, SRS- 22r INA questionnaire is valid and reliable. This questionnaire can be used as an HRQL parameter for AIS patient in Indonesia."

"Kualitas hidup terkait kesehatan merupakan penilaian yang bersifat subyektif. Persepsi pasien dalam menilai aspek-aspek kehidupan yang terdampak oleh penyakit dan prosedur perawatan yang dijalani ini dipengaruhi oleh budaya dimana pasien hidup. Pada masyarakat yang kehidupannya dipengaruhi agama, penilaian pasien ini diprediksi dipengaruhi oleh agama yang dianutnya. Model kualitas hidup terkait kesehatan yang memasukan unsur budaya belum menjelaskan mekanisme hubungan agama terhadap kualitas hidup terkait kesehatan pasien SLE yang hidup dalam konteks budaya Indonesia. Untuk mengenali dan menjelaskan mekanisme pembentukan kualitas hidup ini, perlu ada suatu model teoretis yang dibangun berdasarkan perspektif pasien dan teruji secara empiris. Penelitian ini di laksanakan dengan metode mixed-methods exploratory sequential design. Penelitian terdiri dari 2 tahap, yaitu: tahap penelitian kualitatif dengan metode FGD pada 18 pasien SLE ini dan penelitian cross sectional untuk menguji model teoretis yang dibangun berdasarkan hasil penelitian pertama. Penelitian tahap kedua dilakukan terhadap 328 pasien SLE yang direkrut melalui convenience sampling strategy. Hasil analisis analisis dengan model struktural memperlihatkan bahwa model teoretis yang terdiri dari variabel religiusitas, spiritual support dan depresi sebagai pembentuk kualitas hidup terkait kesehatan psien SLE sesuai dengan data empirik.

---

Health-related quality of life is a subjective appraisal. The patient's perception to about effect of disease and its treatment procedures to their life are influenced by the culture in which the patient lives. In a religious society, such as Indonesia, this appraisal is affected by the religion they adhere to. The health-related quality of life model that incorporates cultural aspects has not yet explained the relationship mechanism between religion and health-related quality of life of patients with SLE who live in Indonesian culture. To identify and explain this mechanism, it is necessary to have a theoretical model that is built based on patient’s perspective and tested empirically. This research was conducted using a mixed-exploratory sequential design method. The study consisted of 2 stages, namely: a qualitative research phase using the FGD method on 18 patients with SLE and a cross-sectional study to test the theoretical model that was built based on the results of the first study. The second phase of the study was conducted on 328 SLE patients who were recruited through a convenience sampling strategy. The analysis by the structural model suggested that the theoretical model consisting of religiosity, spiritual support, and depression variables as determinants of health-related quality of life on patients with SLE was consistent (fit) with the empirical data."

"Erupsi gunung berapi berdampak pada kualitas hidup kesehatan pada masyarakat yang tinggal di daerah bencana, khususnya remaja. Modal sosial merupakan sumber daya potensial dalam meningkatkan kualitas hidup kesehatan remaja. Tujuan penelitian ini untuk mengetahui hubungan modal sosial dengan kualitas hidup kesehatan pada remaja yang terdampak bencana erupsi Gunung Sinabung Kabupaten Karo Provinsi Sumatera Utara. Penelitian ini merupakan penelitian mixed methods dengan embedded sequential design dimana penelitian kualitatif (tahap 1) memberikan peran pendukung sekunder dalam penelitian utama kuantitatif (tahap 2) yang kemudian dilanjutkan dengan penelitian kualitatif (tahap 3) untuk menjelaskan temuan-temuan pada penelitian kuantitatif. Penelitian kuantitatif menggunakan desain cross sectional. Kualitas hidup kesehatan diukur menggunakan kuesioner Pediatric Quality of Life InventoryTM (PedsQLTM) versi 4.0 pada 318 responden berusia 10-18 tahun dengan menggunakan teknik simple random sampling. Data kuantitatif dianalisis menggunakan Regresi Cox. Penelitian kualitatif dengan desain Rapid Assessment Procedure (RAP). Pengumpulan data kualitatif dengan observasi, diskusi kelompok terarah (DKT) dan wawancara mendalam. Hasil penelitian diperoleh proporsi kualitas hidup kesehatan yang buruk sebesar 45,4%. Proporsi remaja dengan modal sosial individu yang rendah sebesar 69,4% dan modal sosial komunitas yang rendah sebesar 47,4%. Modal sosial individu berhubungan dengan kualitas hidup kesehatan (PR = 2,224; 95% CI 1,424-2,473), sedangkan modal sosial komunitas bukan faktor risiko terhadap kualitas hidup kesehatan (PR = 1,017; 95% CI 0,601-1,721). Temuan kuantitatif ini didukung oleh temuan kualitatif bahwa modal sosial pada level individu yang berperan pada kualitas hidup kesehatan yang buruk pada remaja meliputi belum terpenuhinya rasa aman dari erupsi Gunung Sinabung pada remaja yang tidak di relokasi dan remaja membutuhkan rasa aman dari tindak kejahatan; pengalaman yang kurang menyenangkan selama tinggal di pengungsian sementara; kurang akrabnya hubungan sesama anggota masyarakat semenjak tinggal di relokasi; partisipasi remaja rendah dalam organisasi karena rendahnya aksesibilitas transportasi; dan kewajiban yang menjadi beban bagi remaja terutama remaja yang tidak di relokasi. Meskipun modal sosial komunitas bukan faktor risiko kualitas hidup kesehatan remaja, namun secara kualitatif memiliki peran bagi kualitas hidup kesehatan remaja seperti orang tua memanfaatkan keanggotaan dalam organisasi ekonomi untuk biaya pendidikan remaja dan pemanfaatan ruang publik seperti lapangan olahraga dan jambur oleh remaja di relokasi pemerintah yang memberikan kesempatan kepada remaja untuk berinteraksi sosial dengan teman sebayanya dan masyarakat sekitar. Berdasarkan temuan penelitian ini, hendaknya pemerintah daerah dapat memanfaatkan dan melakukan penguatan modal sosial baik pada level individu dan komunitas untuk meningkatkan kualitas hidup kesehatan remaja yang terdampak bencana dengan mempertimbangkan jenis relokasi dan kelompok umur.

---

Volcanic eruptions impact the health and quality of life of people living in disaster areas, especially adolescents. Social capital is a potential resource for improving adolescents’s health-related quality of life. This study aimed to determine the relationship between social capital and health-related quality of life among adolescents affected by the eruption of Mount Sinabung, Karo Regency, North Sumatra Province. This study is a mixed-methods study with an embedded sequential design. A qualitative study (phase 1) provides a secondary supporting role in the main quantitative study (phase 2), which is then followed by a qualitative study (phase 3) to explain the findings in the main quantitative research. Quantitative research using a cross-sectional design. Health-related quality of life was measured using the Pediatric Quality of Life InventoryTM (PedsQLTM) version 4.0 questionnaire on 318 respondents aged 10-18 years using a simple random sampling technique. Quantitative data were analyzed using Cox Regression. Qualitative approach using a Rapid Assessment Procedure (RAP) design. Qualitative data were collected through observation, focus group discussions (FGDs), and in-depth interviews. The results showed that the proportion of poor health-related quality of life was 45.4%. The proportion of adolescents with low individual social capital was 69.4% and low community social capital was 47.4%. Individual social capital was associated with health-related quality of life (PR = 2,224; 95% CI 1,424-2,473), while community social capital was not a risk factor for adolescents' health-related quality of life (PR = 1,017; 95% CI 0,601-1,721). This quantitative finding is supported by the qualitative finding that individual-level social capital that contributes to poor quality of life in adolescents includes the unfulfilled sense of security from the eruption of Mount Sinabung in adolescents who are not relocated and adolescents need a sense of protection from crime; unpleasant experiences while living in temporary refugee camps; lack of familiarity with fellow community members since living in relocation; low participation of adolescents in organizations due to low transportation accessibility; and obligations that become a burden for adolescents, especially adolescents who are not relocated. Although community social capital is not a risk factor for adolescents' health quality of life, it qualitatively plays a role in adolescents' health quality of life, such as adolescents' parents utilizing membership in economic organizations for adolescents' education expenses and the use of public spaces such as sports fields and jambur by adolescents in government relocations that provide opportunities for adolescents to interact socially with their peers and the surrounding community. Based on this study's findings, local governments should be able to utilize and strengthen social capital at both the individual and community levels to improve the quality of life of disaster-affected adolescent health by considering the type of relocation and age group."

"ABSTRAKTuberkulosis (TB) masih menjadi masalah kesehatan di Indonesia dan diKabupaten Pesawaran. Pelaksanaan tugas kesehatan keluarga dapatmempengaruhi kualitas hidup pasien TB di Kabupaten Pesawaran. Penelitian inibertujuan untuk mengetahui hubungan karakteristik klien dan pelaksanaan tugaskesehatan keluarga dengan kualitas hidup klien TB paru. Desain deskriptifkorelatif dengan pendekatan cross-sectional digunakan dalam penelitian pada 41pasien TB berumur 18-59 tahun pada fase intensif pengobatan dari bulan Aprilsampai Mei 2014. Hasil penelitian menunjukkan kualitas hidup klien TBterganggu. Ada hubungan yang signifikan antara pekerjaan (p = 0,034), tugaskesehatan keluarga (p = 0,005), pendapatan (p = 0,030) dan dukungan keluarga (p= 0,012) dengan kualitas hidup klien TB. Pengembangan program yangterintegrasi antara program TB dan perawatan kesehatan masyarakat dan programlainya untuk meningkatkan kemampuan keluarga melaksanakan tugas kesehatankeluarga.

---

ABSTRACTTuberculosis (TB) is a major public health problem in Indonesia as well as inPasawaran. The family health tasks implementation may affect Health RelatedQuality Of Life (HRQOL) among TB patients in Pesawaran. This study aims todetermine the corelation of characteristics of patients and family health tasks toHRQOL TB patients. The descriptive correlative design with cross-sectionalapproach was applied to this study to 41 patients. The inclusion criteria for therespondents are aged range at18-59 years old and under the initial phase of TBtreatment from April to May 2014. The results showed that HRQOL among TBpatients generally were impaired. The characteristics associated to HRQOLamong TB patients were occupation (p = 0.034), family health tasks (p = 0.002),income (p = 0.034) and family support (p = 0.012) . An integrated program needto be developed to increase family’s ability to improve family health tasks."

"Background: sarcopenia contributes to the development of frailty syndrome. Frailty syndrome is potentially improved by modifying insulin resistance, inflammation, and myostatin level. This study is aimed to investigate the effect of metformin on handgrip strength, gait speed, myostatin serum level, and health related quality of life (HR-QoL) among non diabetic pre frail elderly patients.Methods: a double blind randomized controlled trial study was conducted on non-diabetic elderly outpatients aged >60 years with pre frail status based on phenotype and/ or index criteria (Cardiovascular Health Study and/ or Frailty Index 40 items) consecutively recruited from March 2015 to June 2016 at Cipto Mangunkusumo Hospital. One hundred twenty subjects who met the research criteria were randomized and equally assigned into 3 x 500 mg metformin or placebo group. The study outcomes were measured at baseline and after 16 weeks of intervention.Results: out of 120 subjects, 43 subjects in metformin group and 48 subjects in placebo group who completed the intervention. There was a significant improvement on the mean gait speed of metformin group by 0.39 (0.77) second or 0.13 (0.24) meter/second that remained significant after adjusting for important prognostic factors (p = 0.024). There was no significant difference on handgrip strength, myostatin serum level, and HR QoL between both groups.Conclusion: 3 x 500 mg metformin for 16 weeks was statistically significant and clinically important in improving usual gait speed as one of the HR QoL dimensions, but did not significantly improve the EQ 5D index score, handgrip strength, nor myostatin serum level."

"ABSTRAKPenyakit paru obstruktif kronik PPOK menurut The Global Initiative for Chronic Obstructive Pulmonary Disease GOLD adalah salah satu penyakit saluran pernapasan yang tidak dapat menular. Klasifikasi pengelompokan ABCD terbaru didasarkan pada gejala dan penilaian risiko eksaserbasi. Tujuan dari penelitian ini adalah untuk menilai klasifikasi Pengelompokan ABCD pada kualitas hidup yang terkait dengan kesehatan pada pasien dengan PPOK. Metode: Desain penelitian ini menggunakan cross sectional dengan metode convenience sampling pada 200 pasien dengan PPOK stabil yang mengalami PPOK selama lebih dari 3 bulan dan tanpa gagal jantung kronis grade 3 dan 4 di Rumah Sakit Persahabatan, Rumah Sakit Budhi Asih dan Pasar Minggu RSUD. Gejala menggunakan COPD Assessment Test CAT dan kuesioner kualitas hidup menggunakan St George 39s Respiratory Questionnaire SGRQ. Hasil: Analisis Chi Square menunjukkan bahwa p = 0,000.

---

ABSTRACTChronic obstructive pulmonary disease COPD according to The Global Initiative for Chronic Obstructive Pulmonary Disease GOLD is one of the non communicable diseases of the respiratory tract. The latest ABCD Groupings classification is based on symptoms and risk assessment of exacerbations. The aim of this study was to assess the classification of ABCD Groupings on the quality of life associated with health in patients with COPD. Methods The design of this study used cross sectional with convenience sampling method in 200 patients with stable COPD who had COPD for more than 3 months and without chronic heart failure grade 3 and 4 at Persahabatan Hospital, Budhi Asih Hospital and Pasar Minggu Hospital. Symptoms use COPD Assessment Test CAT and quality of life questionnaires using St George 39s Respiratory Questionnaire SGRQ. Result Chi Square analysis shows that p 0,000."

"

Latar Belakang: Perbaikan fungsi fisik, emosional dan kualitas hidup penderita LES harus menjadi bagian penting penatalaksanaan paripurna. Fungsi otot, yang merupakan kombinasi dari kekuatan otot dan performans fisik (Asian Working Group on Sarcopenia 2019), merupakan salah satu determinan penting kualitas hidup subyek LES. Belum ada penelitian evaluasi pengaruh fungsi otot terhadap kualitas hidup penderita LES menggunakan kuesioner Sarcopenia Quality of Life (SarQoL).

Tujuan: Evaluasi hubungan fungsi otot dengan kualitas hidup menggunakan kuesioner SarQoL pada perempuan penderita LES.

Metode: Penelitian potong lintang ini merekrut 61 subyek LES perempuan di klinik Alergi Imunologi, RSCM, secara konsekutif, fungsi otot dinilai dengan dinamometer genggam tangan Jamar (kekuatan otot) dan uji kecepatan berjalan 6 meter (performans fisik), HRQoL dinilai dengan kuesioner Sarcopenia Quality of Life (SarQoL). Kriteria penerimaan perempuan dengan LES berusia ≥18 tahun, tanpa kondisi autoimun lain dan gangguan fungsional/anatomis yang mengganggu pemeriksaan. Analisis statistik menggunakan uji t untuk analisis beda dua rerata dan analisis multivariat regresi linier untuk penyesuaian terhadap perancu.

Hasil: Rerata skor total SarQoL subyek kekuatan otot baik dan rendah didapatkan berbeda signifikan, 74,86 (9,48) vs. 65,49 (15,51) (p=0,009), tetap signifikan setelah disesuaikan usia, asupan protein, tingkat aktivitas olahraga  dan aktivitas penyakit [B -7,12; IK 95% -14,58 –(-1,20)]. Rerata skor total SarQoL subyek dengan kecepatan berjalan baik dan rendah tidak didapatkan berbeda signifikan 70,67 (11,08) vs. 70,72 (13,56) (p=0,993).

Simpulan: Terdapat hubungan signifikan antara kekuatan otot dan kualitas hidup terkait kesehatan menurut SarQoL pada perempuan penderita LES

---

Background: Improvement of physical, emotional function and quality of life of SLE patients, should be an important part of holistic clinical management. Muscle function, a combination of muscle strength and physical performance (Asian Working Group on Sarcopenia 2019), was an important determinant of quality of life in lupus patients. There was no study aimed at evaluating the impact of mucscle function on SLE patient’s quality of life using Sarcopenia Quality of Life (SarQoL) questionnaire.

Aim: This study was conducted to evaluate the relationship of muscle function and SarQoL score in women with SLE.

Methods: This cross-sectional study recruited 61 women with SLE in Allergy-Immunology Clinic of Cipto Mangunkusumo Hospital consecutively, muscle function was measured with Jamar handheld-dynamometer and 6 meter walk test, HRQoL was measured with Sarcopenia Quality of Life (SarQoL) questionnaire. Acceptance criteria include women ≥18 years old with SLE, and not with other autoimmune disease nor functional/anatomical dysfunction that disturb measurements. Statistical analysis was conducted with t-test for mean difference and linier regression was used to adjust confounders.

Results: The difference of total SarQoL score in subjects with good and low muscle strength was found to be significant; 74.86 (9.48) vs. 65.49 (15.51) (p=0.009), statistically significant after adjusments with age, protein intake, physical acitvity level and disease activity [B -7.12; 95% CI -14.58 –(-1.20)]. The difference of total SarQoL score in subjects with good and low physical performance was found to be not significant 70.67 (11.08) vs. 70.72 (13.56) (p=0.993).

Conclusion: There was a significant association between muscle strength and HRQoL according to SarQoL in women with SLE

"

"Pandemi COVID-19 berdampak pada penurunan jumlah pasien ST-Elevation Miocard Infarct (STEMI) tetapi terdapat peningkatan presentasi pasien dengan tindakan reperfusi yang mengalami penundaan. Penundaan ini berakibat pada pemanjangan waktu reperfusi yang memengaruhi Health Related Quality of Life (HRQOL). Penelitian cross-sectional ini bertujuan untuk mengidentifikasi faktor-faktor yang memengaruhi HRQoL pada pasien STEMI yang menjalani terapi reperfusi selama masa pandemi. Sampel penelitian berjumlah 110 responden dengan teknik consecutive sampling. Analisa bivariat menunjukkan jenis kelamin, status hubungan pernikahan, ketepatan waktu reperfusi, tingkat depresi, dan persepsi sakit berhubungan signifikan dengan HRQoL. Analisis multivariat menunjukkan persepsi sakit, ketepatan waktu reperfusi dan status pernikahan merupakan faktor dominan yang memengaruhi HRQoL. Ketiga faktor tersebut menjelaskan variabel HRQoL sebesar 32,6% dan selebihnya 67,4% dijelaskan oleh faktor lain. Peneliti menyarankan untuk dilakukan penelitian lanjutan dengan menggunakan jumlah sampel yang lebih representatif untuk mendapatkan hasil prediktor R2 yang lebih baik dalam mengidentifikasi faktor-faktor lain yang berkontribusi terhadap HRQoL, evaluasi paska tindakan reperfusi menggunakan HRQoL yang multidimensional, edukasi kepada pasien maupun pasangannya, serta evaluasi secara berkala terhadap efektivitas screening COVID-19 untuk pasien STEMI yang datang ke IGD dalam mempertahankan target terapi reperfusi.

---

The COVID-19 pandemic has resulted decreasing in the number of ST-Elevation Myocardial Infarct (STEMI) patients but there has been an increase in the presentation of patients with delayed reperfusion. This delay results in a prolonged reperfusion time which affects Health-Related Quality of Life (HRQOL). This cross-sectional study aims to identify the factors that influence HRQoL in STEMI patients undergoing reperfusion therapy during the pandemic. The research sample was 110 respondents with consecutive sampling techniques. Bivariate analysis showed that gender, marital relationship status, the timeliness of reperfusion, level of depression, and illness perception were significantly related to HRQoL. Multivariate analysis showed illness perception, timeliness of reperfusion and marital status were the dominant factors influencing HRQoL. These three factors explained the HRQoL by 32.6% and the remaining 67.4% was explained by other factors. Researcher suggests further research to be conducted using a more representative sample size to obtain better R2 predictor results in identifying other factors that more contribute to HRQoL, post-reperfusion evaluation using multidimensional HRQoL, educating patients and their partners, as well as comprehensive evaluation on the effectiveness of COVID-19 screening for STEMI patients who come to the ED to maintain the target of reperfusion therapy."

"Berdasarkan data Global Cancer Observatory (GLOBOCAN) 2022, jumlah kasus kanker baru di Indonesia diperkirakan 408.661 kasus dan jumlah kematian akibat kanker di Indonesia diperkirakan 242.988 kematian. Penatalaksanaan penyakit kanker tidak terbatas pada penanganan penyakit secara klinis, tetapi juga harus melibatkan rencana penatalaksanaan yang dapat memberikan kualitas hidup terbaik secara keseluruhan. Health-Related Quality of Life (HRQoL) pasien kanker merupakan persepsi pasien terhadap efek penyakit dan/atau pengobatan dan dianggap sebagai hasil terapi yang penting pada pasien kanker. Perlu diketahui faktor-faktor yang berhubungan dengan HRQoL pasien kanker agar pemangku kebijakan dapat menyusun kebijakan yang sesuai. Metode penelitian yang digunakan adalah metode cross-sectional dengan pendekatan kuantitatif menggunakan kuesioner EQ-5D-5L. Hasil analisis menunjukkan bahwa dari 14 variabel yang diteliti terdapat 4 variabel yang terbukti signifikan berhubungan, yaitu tingkat pendidikan (p = <0,001), pendapatan (p = 0,043), operasi (p = 0,022) dan komorbid (p = 0,007). Faktor dominan yang berhubungan signifikan dengan HRQoL pasien kanker adalah tingkat pendidikan (p = 0,000 dan B -0,430). Faktor-faktor yang berhubungan dengan HRQoL pasien kanker perlu menjadi target intervensi para pemangku kebijakan. Pendidikan mampu meningkatkan pemberdayaan pasien kanker. Edukasi untuk pasien kanker menjadi hal yang penting sehingga pemahaman yang baik dari pasien kanker terhadap penyakit yang diderita dapat memengaruhi HRQoL agar menjadi lebih baik.

---

Based on data from the Global Cancer Observatory (GLOBOCAN) 2022, the number of new cancer cases in Indonesia is estimated at 408,661 cases and the number of cancer deaths in Indonesia is estimated at 242,988 deaths. Cancer management is not limited to clinical disease management, but must also involve a management plan that can provide the best overall quality of life. Health-Related Quality of Life (HRQoL) of cancer patients is the patient's perception of the effects of disease and/or treatment and is considered an important therapeutic outcome in cancer patients. It is necessary to know the factors associated with HRQoL of cancer patients so that policy makers can develop appropriate policies. The research method used was a cross-sectional method with a quantitative approach using the EQ-5D-5L questionnaire. The results of the analysis showed that of the 14 variables studied there were 4 variables that proved to be significantly related, namely education level (p = <0.001), income (p = 0.043), surgery (p = 0.022) and comorbidities (p = 0.007). The dominant factor significantly associated with HRQoL of cancer patients was education level (p = 0.000 and B -0.430). Factors associated with HRQoL of cancer patients need to be targeted for intervention by policy makers. Education can increase the empowerment of cancer patients. Education for cancer patients is important so that cancer patients' good understanding of their disease can affect their HRQoL for the better."