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Ditemukan 2 dokumen yang sesuai dengan query
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Ahmad Faris Aldjoefrie
Abstrak :
Kacang panjang (Vignaunguiculata) merupakan tanaman popular dalam dunia kuliner namun memiliki khasiat di setiap bagian tanaman. Contohnya pada daunnya digunakan secara tradisional dalam jamu kuno bernama Au Fere II berasal dari Maluku berkhasiat sebagai antihipertensi atau mengatasi tekanan darah tinggi. Secara sederhana obat berprinsip “satu obat,satu penyakit” berakibat dalam penemuan obat terbaru mengalami perlambatan sehingga efektivitas terapi menurun. Dengan hadirnya jejaring farmakologi layaknya jamu dengan terobosan terbaru dari sistem biologi, bioinformatika dapat menggantikan prinsip menjadi berdasarkan teori jaringan dan sistem biologi “jaringan target, banyaknya senyawa dalam terapi”. Sehingga efektif dalam membangun hubungan senyawa-target dan target-penyakit. Atas dasar ini, peneliti bertujuan mengungkapkan khasiat dari senyawa daun kacang panjang sebagaimana penggunaan tradisionalnya dengan metode jejaring farmakologi serta dibangunnya jaringan “senyawa-target” serta “target-penyakit” sehingga efektif untuk mencari keterkaitannya. Hasil dari pembuatan metode ini didapatkan 11 senyawa, 17 target, 188 penyakit dalam 24 kategori penyakit. Jumlah terbanyak kategori penyakit adalah penyakit syaraf, genetic, fenotipe. Sesuai dengan penggunaan tradisional, terbukti daun kacang panjang berkhasiat sebagai antihipertensi dengan terbentuknya jaringan dari 7 senyawa, 4 target, 23 penyakit terkait pada penyakit kardiovaskular. Dengan didapatkannya hasil tersebut, peneliti berhasil mengungkapkan khasiat senyawa pada daun kacang panjang dengan terbentuknya jaringan dan hubungannya beserta rincian komponen pendukung proses ini. ......Cowpea (Vigna unguiculata) is popular plant in culinary world but has properties in every part of plant. Example, leaves traditionally used in ancient herb, Au Fere II from Maluku has antihypertensive or treats high blood pressure. In simple terms, medicine has principle "one drug, one disease" resulting in discovery of latest drugs slowing down so that effectiveness of therapy decreases. And existence of network pharmacology like herbal with breakthroughs in biological systems, bioinformatics, network theory can replace principle "target network, many compounds in therapy". Effective in establishing compound-target and disease-target relationships. On this basis, researchers aim to reveal the efficacy of cowpea leaves compounds as traditional use with network pharmacology and construction "compound-target" and "disease-target" networks so effective in finding links. Results of method obtained 11 compounds, 17 targets, 188 diseases in 24 categories. Highest number of disease categories are neurological, genetic, phenotype diseases. Accordance with traditional use, cowpea leaves are proven to be efficacious as antihypertensives by forming network of 7 compounds, 4 targets, 23 diseases related to cardiovascular disease. By obtaining results, researchers were able to reveal the efficacy of compounds in cowpea leaves with formation of networks and relationships, along with details of components supporting this process.
Depok: Fakultas Farmasi Universitas Indonesia, 2023
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UI - Skripsi Membership  Universitas Indonesia Library
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Nathapong Matintarangson
Abstrak :
ABSTRACT
The experimental field was planted at Pathum Thani Province to assess the effects of marigold and yardlong bean intercropping on a number of cowpea aphids, a number of natural enemies, growth and yield of yardlong bean and insect bio-diversity. The experimental design was a randomized complete block design (RCBD) with four treatments each of which was replicated three times. Each of the 12 plots measured 7 m x 5 m in the experiment. The distance between inter and intra row spacing for all treatments was 70 x 50 cm with 1 m spacing between plots. The intercropping treatments were: sole yardlong bean (T1), 1 row of yardlong bean with 1 row of marigold (T2), 2 rows of yardlong bean with 1 row of marigold (T3) and 3 rows of yardlong bean with 1 row of marigold (T4). The results showed that intercropping yardlong bean with marigold had significant (p<0.05) effect on the number of cowpea aphids, the number of natural enemies, growth and yield of yardlong bean and insect bio-diversity when compared with the sole yardlong bean. The 1 row yardlong bean + 1 row marigold had the lowest number of cowpea aphids from week1 to week6 when compared with other intercropping. The 1 row yardlong bean + 1 row marigold were value with 26.32+1.24, 42.00+0.61, 65.33+1.69, 70.33+1.69, 110.66+1.24 and 145.00+1.63 aphids/ 5 yardlong, ladybird beetles (34.60 + 1.24), black ant (30.80 + 1.24) and spider (17.33 + 0.94), plant height and weight (42.25 + 0.82 cm and 2.75 + 0.82 kg) and insect bio-diversity (1.44). Therefore, intercropping yardlong bean with marigold is an effective practice in the control of cowpea aphids and enhancing insect bio-diversity.
Pathum Thani: Thammasat University, 2018
670 STA 23:2 (2018)
Artikel Jurnal  Universitas Indonesia Library