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"Leptospirosis is a zoonotic disease cause by a microorganism? leptospira, with animals especially rats acting as the reservoir host. Humans are infected by direct contact with urine or tissues of the infected animals and indirectly by contaminated water, soil, and vegetation leptospira. Infection can result in acute renal failure, or liver damage and pancreas.In this case patient with the problem is leptospirosis, acute pancreatitis and acute renal failure. Serologic test resulted in positive leptospira with titer 400 for serovar Hardjo and titer 100 for serovar Bataviae."

"Administration of a renal dose of dopamine in acute renal failure still attracts a lot of controversy, store there has not been a study that found a significant protective effect on the kidneys.Nevertheless, according to its ability to increase renal blood flow in laboratory animals and normal subjects, several parties still maintain its use, even though the required dose is very much individualized.The side effect of dopamine, such as tachycardia, arrhythmia, miocardiac ischemia, and intestinal ischemia due to precapilary vasoconstriction causing bacterial translo-caiionfrom the intestinal lumen to the systemic bloodstream, even though relatively rare, should receive adequate attention."