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Hasil Pencarian

Ditemukan 3 dokumen yang sesuai dengan query
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Aditya Dwi Septiawan
Analisis ekspresi protein zip 1 dan caspase-3 pada adenokarsinoma prostat = Analysis expression of zip1 and caspase-3 protein in adenocarsinoma prostate
" [Pendahuluan: Proses karsinogenesis adenokarsinoma prostat terjadi akibat disregulasi kadar zinc dalam sel. Molekul zinc intrasel berperan dalam metabolisme aerob mitokondria dan induksi apoptosis. Penyerapan zinc diatur oleh protein ZIP1, berperan meningkatkan kandungan zinc sitoplasmik intrasel dengan membawa zinc dari cairan ekstrasel. Kadar zinc yang tinggi dan ekspresi protein ZIP1 banyak ditemukan pada epitel prostat normal, sedangkan pada kanker prostat ditemukan sedikit atau tidak ada ekspresi protein ZIP1. Penurunan ekspresi ZIP1 diduga dapat menghambat apoptosis, serta ... "
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Aditya D. Septiawan
Analysis expression of ZIP1 and caspase-3 protein in adenocarsinoma of the prostate
" Objective: Carcinogenesis of adenocarcinoma of the prostate occurs due to dysregulation of zinc level within the cells. Intracellular zinc molecules influx is regulated by a transporter protein ZIP1, whose non-presence is predicted to inhibit apoptosis, thus leads to the development of prostate adenocarcinoma. Methods: This study was aimed to analyze the correlation of ZIP1 and Caspase-3 expression in prostate adenocarcinoma on its grading as represented by Gleason Score. This was a cross-sectional, retrospective analytical study ... "
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2016
J-Pdf
Artikel Jurnal  Universitas Indonesia Library
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Aditya D. Septiawan
Analysis expression of ZIP1 and caspase-3 protein in adenocarsinoma of the prostate / Aditya D Septiawan, Ria Kodariah, Meilania Saraswati
" Objective: Carcinogenesis of adenocarcinoma of the prostate occurs due to dysregulation of zinc level within the cells. Intracellular zinc molecules influx is regulated by a transporter protein ZIP1, whose non-presence is predicted to inhibit apoptosis, thus leads to the development of prostate adenocarcinoma. Methods: This study was aimed to analyze the correlation of ZIP1 and Caspase-3 expression in prostate adenocarcinoma on its grading as represented by Gleason Score. This was a cross-sectional, retrospective analytical study on 31 formalin-fixed, paraffin-embedded ... "
Fakultas Kedokteran Universitas Indonesia, 2016
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Artikel Jurnal  Universitas Indonesia Library