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Abstrak :
Fitosom merupakan salah satu nanovesikel lipid yang dapat meningkatkan absorbi zat aktif. Ekstrak teh hijau diformulasikan menjadi fitosom. Tujuan untuk melihat kemampuan fitosom menghambat kenaikan berat badan. Tiga formula dengan hidrasi lapis tipis, selanjutkan dikarakterisasi pembentukan kompleks fitosom, morfologi, ukuran partikel, zeta potensial, indeks polidispersitas , dan uji efisiensi penjerapan. Fitosom dan ekstrak teh hijau diuji absorbsi secara in vitro. Sebanyak 25 ekor tikus dibagi menjadi lima kelompok uji, kelompok normal, plasebo, orlistat, ekstrak teh hijau dan fitosom. Selama 8 minggu diinduksi peroral menggunakan fruktosa 10% + kolesterol 2% dan perlakuan uji. Karakteristik terbaik FIII terbentuk kompleks, morfologi bentuk sferis, Dv90 782,67 ± 39,7 nm, polidispersitas indeks 56 ± 0,11, zeta potensial -70,83 ± 1,67 mV, dan efisiensi penjerapan 97,77 ± 2,66%. Hasil pengujian terhadap hewan uji pada minggu ke-8 persentase kenaikan berat badan pada perlakuan normal 46,47 ± 17,48 %, plasebo 101,17 ± 10,37%, orlistat 42,51 ±25,13 %, ekstrak teh hijau 92,73 ± 36,43 %, dan fitosom 45,09 ± 15,56 %. Fluks ekstrak teh hijau sebesar 2.316,2 ± 1309,8 µg/cm2/jam dan fitosom 3.125,3 ± 2071,8 µg/cm2/jam. Kesimpulan dari penelitian ini adalah fitosom dapat menghambat kenaikan berat badan dan lebih baik jika dibandingkan dengan ekstrak teh hijau (p < 0,05).

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Phytosomes are one of the lipid nanovesicles that can increase the absorption of active substances. Green tea extract is formulated into phytosomes. The goal is to see the ability of phytosomes to inhibit weight gain. Three formulas with thin layer hydration were further characterized by phytosome complex formation, morphology, particle size, zeta potential, polydispersity index, and entrapment efficiency. Phytosomes and green tea extracts were tested for absorption in vitro. A total of 25 rats were divided into five test groups, the normal group, placebo, orlistat, green tea extract and phytosomes. For 8 weeks orally induced using fructose 10% + 2% cholesterol and treatment. The best characteristics of FIII are complex, spherical morphology, Dv90 782.67 ± 39.7 nm, polydispersity index 56 ± 0.11, zeta potential -70.83 ± 1.67 mV, and entrapment effiiency 97.77 ± 2.66 %. Test results on test animals at 8 weeks percentage of weight gain in normal treatment 46.47 ± 17.48%, placebo 101.17 ± 10.37%, orlistat 42.51 ± 25.13%, green tea extract 92, 73 ± 36.43%, and fitosomes 45.09 ± 15.56%. Green tea extract flux was 2,316.2 ± 1309.8 µg/cm2/hour and phytosomes 3,125.3 ± 2071.8 μg/cm2/hour. The conclusion of this study is that phytosomes can inhibit weight gain and are better when compared to green tea extracts (p <0.05).

Abstrak :
Belum banyak bukti ilmiah yang mendukung efektivitas cuka apel. Namun, penggunaannya sebagai agen penurun berat badan telah semakin meluas. Bahkan, di berbagai iklan penjualan produk, suplemen makanan ditampilkan seolah-olah memiliki manfaat seperti obat. Untuk itu, peneliti mengadakan penelitian eksperimental dan hipotesis yang akan diuji adalah efektivitas cuka apel tak sebaik yang dimiliki obat standar dalam menurunkan berat badan tikus strain Sprague Dawley. Tikus Sprague Dawley dengan berat 190- 250 gram digunakan sebagai sampel dalam penelitian ini. Ada 24 ekor tikus yang terbagi ke dalam 3 kelompok, yaitu kelompok kontrol (sebagai kontrol negatif), kelompok mazindol (sebagai kontrol positif), dan kelompok cuka apel. Ketiganya mendapat jenis makanan dan minuman yang sama. Berat badan dan tingkah laku tikus diamati selama dua minggu. Data berat badan sebelum dan sesudah terapi diambil dan dianalisis menggunakan uji hipotesis One Way Anova. Peneliti mendapati tidak adanya penurunan berat badan pada ketiga kelompok perlakuan. Akan tetapi, berat badan tikus terus mengalami peningkatan dari hari ke hari. Data peningkatan berat badan tersebut menunjukkan adanya perbedaan bermakna secara statistik antara kelompok kontrol dan kelompok cuka apel (p = 0,012). Sementara itu, tidak adanya perbedaan bermakna terlihat baik antara kelompok kontrol dan mazindol maupun kelompok mazindol dan cuka apel. ...... There is not much scientific evidence supporting the effectiveness of apple cider vinegar. However, its use as a weight loss agent has been increasingly widespread. In fact, in various advertising sales of products, food supplements appear as if it has benefits such as drugs. For that reason, researchers conducted experimental research and hypotheses to be tested is not as good as the effectiveness of apple cider that has a standard drug in losing weight strain of Sprague Dawley rats. Sprague Dawley rats weighing 190-250 grams are used as samples in this study. There were 24 rats divided into 3 groups, namely the control group (as a negative control), mazindol group (as positive control), and apple vinegar. All of those got kind of the same foods and beverages. Weight and attitude of rats were observed for two weeks. Weight data before and after therapy was taken and analyzed using One Way Anova test hypotheses. Researchers found no change in body weight in all three treatment groups. However, the weight of rats continued to increase from day to day. Weight gain data showed a statistically significant difference between control group and apple cider vinegar group (p = 0.012). Meanwhile, there is no significant differences either between control group and mazindol group or between mazindol group and apple cider vinegar group.

Abstrak :
Kadar CRP serum dapat digunakan sebagai prediktor penurunan berat badan dan indikator prognostik inflamasi. Penelitian ini dilakukan untuk mengetahui korelasi kadar CRP serum dengan penurunan berat badan dan mukositis oral pada pasien kanker kepala leher yang menjalani radioterapi. Penelitian ini adalah penelitian observasional dengan desain potong lintang pada pasien kanker kepala leher yang telah menjalani terapi radiasi minimal 25 kali di Departeman Radioterapi RSUPNCM Jakarta dengan usia ge;18 ndash;65 tahun. Hasil penelitian menunjukkan bahwa sebagian besar subyek 71,2 memiliki kadar CRP serum normal, mengalami penurunan berat badan ge;5 dalam waktu sebulan 76,9 dengan rerata penurunan berat badan -9,42 7,76 , dan juga mengalami mukositis oral 65,4 dengan persentase terbanyak yaitu derajat 1 59,6 . Tidak terdapat mukositis oral derajat 3 dan 4. Tidak terdapat korelasi antara kadar CRP serum dengan penurunan berat r=0,166; p=0,239 , dan mukositis oral r=0,137; p=0,331 . Kesimpulan adalah kadar CRP serum saat radioterapi tidak memengaruhi penurunan berat badan dan mukositis oral. Sebagian besar subyek tetap mengalami penurunan berat badan selama menjalani radioterapi sehingga pemasangan NGT yang lebih awal yaitu sebelum terapi radiasi dimulai NGT profilaksis perlu dilakukan, namun hal ini membutuhkan penelitian lebih lanjut. ......Serum CRP levels can be used as a predictor of weight loss and prognostic indicator of inflammation. This study was conducted to determine the correlation of serum CRP levels with weight loss and oral mucositis in patients with head and neck cancer undergoing radiotherapy. This study was an observational study in the head and neck cancer patients who have undergone radiation therapy at least 25 times at the Department of Radiotherapy RSUPNCM Jakarta with aged ge 18 ndash 65 years old. Our study results showed that most of the subjects 71,2 had normal serum CRP levels, weight loss of ge 5 in one month 76,9 , and also experienced oral mucositis 65,4 . Mostly had grade 1 oral mucositis 59,6 . There were no grade 3 and 4 oral mucositis.There were no correlation between serum CRP levels with weight loss r 0,166 p 0,239 , and oral mucositis r 0,137 p 0.331 . In conclusion, serum CRP levels did not influence weight loss and oral mucositis in patients with head and neck cancer undergoing radiotherapy. Most of the subjects still experienced weight loss during radiotherapy. Therefore, NGT prophylaxis is needed, but this requires further study.

Abstrak :
Albumin serum, berat badan dan kekuatan genggaman merupakan parameter penilaian status gizi yang berhubungan dengan kadar protein tubuh. Penelitian ini dilakukan untuk mengetahui korelasi antara kadar albumin serum terhadap persentase penurunan berat badan dan kekuatan genggaman. Penelitian dengan desain potong lintang pada pasien kanker kepala leher dengan usia ≥18–65 tahun yang telah menjalani radiasi ≥25 kali di Departemen Radioterapi RSUPNCM. Hasil penelitian menunjukkan sekitar 55,76% subjek memiliki kadar albumin <3,4 g/dL. Rerata penurunan berat badan selama radiasi – 9,42 ± 7,76%, dengan 79,6% subyek mengalami penurunan berat badan ≥5%. Rerata kekuatan genggaman tangan dominan 39,48 ± 9,15 kg. Tidak terdapat korelasi antara kadar albumin serum dengan persentase penurunan berat badan (r = - 0,129; p = 0,364) dan kekuatan genggaman tangan (r = 0,048; p = 0,733). Kesimpulan, kadar albumin serum tidak memengaruhi penurunan berat badan dan kekuatan genggaman selama radiasi. Sangat penting untuk mempertahankan status gizi selama menjalani radioterapi salah satunya dengan pemakaian NGT di awal radiasi. Diperlukan penelitian lebih lanjut dengan desain kohort prospektif untuk mendapatkan data yang lebih konklusif. ......Serum albumin, body weight and hand grip strength is a parameter of assessment of nutritional status related to body protein. This study was conducted to determine the correlation between serum albumin levels with the percentage of weight loss and hand grip strength. A cross sectional study design in the head neck cancer patients with ge 18 65 years of age who have undergone radiation at least 25 times in the Department of Radiotherapy RSUPNCM. The results showed approximately 55,76 of the subjects had levels of albumin below 3,4 g dL. Mean weight loss during radiation ndash 9,42 7,76 , with 79,6 of subjects experienced weight loss ge 5 . Mean dominant hand grip strength 39,48 9,15 kg. There is no correlation between serum albumin levels with percentage of body weight loss r 0,129 p 0,364 and hand grip strength r 0,048 p 0,733 . Conclussion, serum albumin levels did not affect body weight loss and handgrip strength during radiation. It is essential for head and neck cancer patients undergoing radiotherapy to maintain nutritional status with NGT in the initial radiation. Further research with prospective cohort design is needed to obtain more conclusive data. Keywords Serum albumin, weight loss percentage, handgrip strength, head and neck cancer, radiotherapy

Abstrak :
Ibu post partum akan mengalami penurunan berat badan secara alami antara 5 kg sampai 11 kg. Penelitian ini bertujuan mengetahui faktor-faktor yang menyebabkan penurunan berat bada pada ibu post partum. Penelitian deskriptif analitik dengan desain menggunakan cross-sectional pada 162 ibu post partum yang mempunya bayi umur 6 sampai 11 bulan. Hasil penelitian menunjukkan ada hubungan pemberian ASI ekslusif terhadap penurunan berat badan ibu post partum. Variabel yang dominan terhadap penurunan berat badan adalah ASI ekslusif. Ibu yang memberikan ASI ekslusif berpenluang 28.244 kali terjadi penurunan berat badan dibandingkan ibu yang tidak memberikan ASI ekslusif. Rekomendasi diharapkan perawat maternitas dapata menetapkan asuhan keperawatan pada ibu post partum untuk memberikan ASI ekslusif pada bayinya.

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Naturally, after bear a child, women body weight will be descend in 5 to 11 kg. This research is purpose to know what factors contribute to descend this body weight. This descriptive analytics research, with cross-sectional, in 162 post-partum women who had baby with 6-11 months years. Results of this research shows that there is relation between the exclusive mother breast feeding and descending of bosy weight in post partum women. The exclusive mother breast feeding gives 28.244 opportunities to descend of body weight in post-partum women than they who are not. This recommendation expected that the maternity nurses will determine nursing care in post partum women to provide the exclusive mother breat feeding to their baby.

Abstrak :
Tujuan penelitian adalah diketahuinya pengaruh pemberian suplementasi makanan cair 500 kalori per hari berturut-turut dari awal radiasi sampai radiasi ke 20 terhadap kadar albumin serum dan berat badan pasien kanker nasofaring yang menjalani kemoradioterapi. Penelitian ini merupakan uji klinis paralel, membandingkan kelompok yang mendapat suplementasi makanan cair disertai penyuluhan gizi dan diet sehari-hari (P) dengan kelompok yang hanya mendapat penyuluhan gizi dan diet sehari-hari saja (K). Sebanyak 18 pasien kanker nasofaring yang menjalani kemoradioterapi yang memenuhi kriteria dibagi dalam dua kelompok secara randomisasi blok. Data yang diambil meliputi usia, jenis kelamin, indeks massa tubuh, stadium penyakit, asupan energi dan protein dengan food recall 1 x 24 jam Serta kebutuhan energi dan protein dengan rumus Harris- Benedict. Pemeriksaan kadar albumin semm Serta berat badan dilalcukan pada awal dan akhir perlakuan. Analisis data menggunakan uji t tidak berpasangan dan berpasangan Serta uji Mann Whitney dengan batas kemaknaan 5%. Diperoleh 8 orang di kelompok P dan 8 orang di kelompok K dengan usia 18-59 tahun yang mengikuti penelitian secara lengkap. Tidak ada perbedaan data awal yang bermakna antara kelompok P dan kelompok K. Pcnurunan ltadar albumin serum pada kelompok P Iebih rendah daripada kelompok K. Diperoleh rerata persentase penurunan berat badan pada kelompok P yang kurang 2,24 % dari kelompok K, namun secara statistik tidak bermakna. Pemberian suplementasi makanan cair 500 kalori per hari berturut-turut dari awal radiasi sampai radiasi ke 20 tidak dapat mempertahankan kadar albumin serum dan mengurangi rerata persentase penurunan berat badan pada kelompok perlakuan. ......The aims of this study were to investigate the influence of 500 calorie per day liquid food supplementation from the first day of chemoradiotherapy until twenty times radiation therapy on serum albumin level and body weight in nasopharynx cancer patients undergoing chemoradiotherapy. The study was a parallel randomized clinical trial.` Eighteen subjects of nasopharynx cancer patients treated with a targeted chemoradiotherapy were selected using certain criteria. The randomly (block randomization) eighteen subject were divided into two group. The treatment group received 500 calorie per day liquid food supplementation from the first day of treatment until twenty times radiation therapy, nutrition counseling and daily diet; the control group received nutrition counseling and daily diet alone. This study was conducted at Dr. Cipto Mangunkusumo Hospital Department of Radiotherapy. Data collected included age, gender, body weight and tall, body mass index, intake of energy and protein, and using l x 24 hours food recall. Laboratory 'findings (serum albumin levels) were done before and after intervention. For statistical analysis, impaired t-test, paired t-test and Mann Whitney were used with the level of significance was 5%. Eight subjects in the treatment group and Eight subjects in the control group completed the study and analyzed. The characteristic data of the two groups at baseline were not significantly different, therefore they were closely matched at baseline. There were decrease of serum albumin in both group, but it was lower in the treatment group than the control group, although it is not statistically significant (p>0,05). There were a 23,24 % relative reduction in weight loss in the treatment group but it is not statistically significant. In conclusions, the influence of 500 calorie per day liquid -food supplementation from the first day of chemo radiotherapy until twenty times radiation' did not preserve serum albumin level and were not reduction in weight loss in the treatment group.

Abstrak :
Remaja dengan kelebihan berat badan harus diintervensi agar tidak menjadi orang dewasa dengan obesitas. Berkembangnya patient-centered care sebagai upaya pemberdayaan diri dapat menjadi pendekatan terpilih. Dibutuhkan motivasi besar dalam menjalani proses perubahan perilaku. Coaching dilakukan untuk mendampingi klien (coachee) agar mampu mengoptimalkan potensi sehingga memiliki sikap positif, mental yang kuat, dan gaya hidup yang lebih baik. Belum ada penelitian yang mengidentifikasi keberhasilan patient-centered care berbasis pemberdayaan diri dengan metode coaching pada mahasiswa obesitas. Penelitian dilakukan dengan mixed method dalam tiga tahap. Tahap 1 merupakan studi potong lintang untuk mengidentifikasi persepsi mahasiswa terhadap dampak obesitas bagi kesehatan. Kuesioner daring terdiri dari identitas, data antropometri, S-Weight, dan P-Weight. Tahap 2 dilakukan pengembangan model pelayanan dengan cara melaksanakan focus group discussion. Peserta diskusi adalah pakar di tingkat mikro, meso dan makro sistem layanan kesehatan. Tahap 3 menilai kemamputerapan dan efektivitas model layanan yang dikembangkan. Studi dilakukan pada dua kelompok mahasiswa obesitas (usia 18-24 tahun) yang dibagi dalam kelompok intervensi dan kontrol. Pada kedua kelompok diberlakukan model layanan yang sama yaitu pengukuran status antropometrik dan komposisi tubuh, pengisian kuesioner pada awal program, edukasi, dan kembali dilakukan pengukuran status antropometrik dan komposisi tubuh serta pengisian kuesioner pada akhir program. Pada kelompok intervensi ditambahkan uji coba coaching sebanyak 6 sesi setiap dua minggu. Pengukuran awal dan akhir berjarak 3 bulan. Tahap 1 diperoleh 134 mahasiswa obesitas (respons rate 14.1%). Teridentifikasi responden berada pada tahap kontemplasi (35,8%) dan aksi (35,1%) terhadap perubahan perilaku dalam proses menurunkan berat badan. Kesiapan responden bersifat positif (76,9%) pada emosi, dan bersifat negatif pada konsekuensi, dukungan, dan aksi dalam menurunkan berat badan. Tahap 2 dilaksanakan dua tahap FGD terhadap 2 kelompok @ 10 orang. Teridentifikasi bahwa program penurunan berat badan harus diinisiasi dengan membangkitkan rasa kebutuhan untuk lebih sehat dengan berat badan yang ideal. Program harus bersifat personal. Diperlukan dukungan lingkungan seperti ketersediaan makanan sehat dan sarana untuk beraktivitas. Program harus merupakan program yang menimbulkan dukungan terhadap peserta, profesional, dan tersedia di layanan kesehatan. Berdasarkan hal tersebut disusun metode coaching yang sesuai dengan patient-centered care berbasis pemberdayaan diri bagi mahasiswa obesitas dalam program penurunan berat badan. Program terdiri dari 6 sesi coaching. Setiap tema dalam sesi coaching menggunakan langkah SMART dan diberi nama “From Fat to Fit with SMART Program”. Program dilaksanakan dalam waktu 3 bulan. Tema berturut-turut adalah healthy behavior habit, vision strategy, body self-image, timeline perspective/ state line exercise, happiness model, dan healthy behavior habit/ vision board. Kedua kelompok mendapatkan edukasi mengenai dampak obesitas bagi kesehatan, prinsip gizi seimbang, aktivitas fisik dan hidrasi yang sesuai bagi remaja dari para ahli yang terdiri dari spesialis penyakit dalam, spesialis gizi klinik, dan spesialis kedokteran olahraga yang dilakukan secara daring. Pengukuran antropometri, komposisi tubuh (menggunakan Bioelectric Impedance Analysis), pemantauan asupan makanan (menggunakan formulir food record), pemantauan aktivitas fisik (menggunakan bouchard activity record), pemberdayaan diri (menggunakan kuesioner subjective wellbeing dan skala kepuasan healthy behavior habit), dibandingkan antara dua kelompok menggunakan uji T berpasangan (jika distribusi data normal) dan uji Mann-Whitney (jika distribusi data tidak normal). Tahap 3 diawali dengan penerapan program terhadap dua kelompok @ 30 mahasiswa obesitas. Peserta dibagi menjadi kelompok intervensi dan kelompok kontrol. Kelompok intervensi mendapatkan coaching dari health coach yang telah mendapatkan pelatihan sebelumnya dari coach bersertifikat Internasional. Seorang health coach mendampingi 4 mahasiswa obesitas. Health coach berjumlah 8 orang yang terdiri dari dokter spesialis kedokteran keluarga layanan primer, dokter spesialis penyakit dalam, dokter spesialis kedokteran olahraga, dokter pengelola program studi fakultas, dan coach yang berpengalaman dengan pendekatan coaching di tempat kerjanya. Sesi coaching dibagi menjadi enam pertemuan setiap dua minggu secara daring melalui media zoom meeting dengan bantuan host dari tim peneliti. Namun, meningkatnya kondisi PPKM (pemberlakuan pembatasan kegiatan masyarakat) pada tahap ini, mahasiswa yang berhasil menyelesaikan program adalah 23 mahasiswa kelompok intervensi dan 18 mahasiswa kelompok kontrol. Nilai perubahan pada kelompok intervensi secara signifikan lebih besar dibandingkan kelompok kontrol pada komponen total lemak tubuh [-0.9 (-12,9, 0,70) vs 0,0 (-6,9, 3,50), p=0,02) dan healthy behavior habit [13.5 ± 11,85 vs 7,5 ± 8,08, p=0,04]. Nilai perubahan skala kepuasan healthy behavior habit secara signifikan lebih besar dibandingkan kelompok kontrol pada aspek hobby/passion [2(-4,6) vs 1(-2,2), p=0,02], movement exercise [2,3 ± 2,11 vs 1,2 ±1,93, p=0,03], sleep rest [2(-6,5) vs 1(-3,2), p=0,01], dan spiritual [1(0,6) vs 0( -1,3), p=0,00]. ......Adolescents with excess weight should be intervened so as not to become adults with obesity. The development of patient-centred services as an effort to empower oneself could be the approach of choice. It takes great motivation in undergoing the process of behaviour change. Coaching is carried out to assist the client (coachee) to optimize their potential so that they had a positive attitude, strong mentality, and a healthier lifestyle. There has been no research that has identified the success of patient-centred care based on self-empowerment with coaching methods for obese students. Mixed method research were in three stages. Phase 1 was a cross-sectional study to identify students' perceptions of the impact of obesity on health. The online questionnaire consisted of identity, anthropometric data, S-Weight, and P-Weight. Phase 2 was developing a service model by conducting focus group discussions. Discussion participants were experts at the micro, meso, and macro levels of the health care system. Phase 3 assessed the applicability and effectiveness of the developed service model. The study was conducted on two groups of obese college students (aged 18-24 years) in the intervention group and the control group. Both groups were subjected to the same service model, namely an initial physical examination, a questionnaire at the beginning of the service, and education about how to lose weight. A final physical examination and questionnaire were carried out at the end of the program. However, the intervention group was given a coaching method. Initial and final examinations were 3 months apart. Phase 1 obtained 134 obese students (response rate of 14.1%). Respondents identified as being in the contemplation stage (35.8%) and action (35.1%) on behaviour change in the process of losing weight. Respondents' readiness was positive (76.9%) on emotions about losing weight and was negative in terms of consequences, support, and action in losing weight. Phase 2 was carried out in 2 stages of FGD with 2 groups of 10 people. It was identified that a weight loss program should be initiated by generating a sense of the need to be healthier with ideal body weight. Programs should be personal. Environmental support was needed such as the availability of healthy food and facilities for activities. The intervention program should be a program that creates support for participants, professional, and available in health services. Based on this, a coaching method was developed following patient-centred care based on self-empowerment for students with obesity in weight loss programs. The program consisted of 6 coaching sessions. Each session used SMART steps. Each coaching session was themed sequentially and was named “From Fat to Fit with SMART Program”. The program was implemented within 3 months. The successive themes of the coaching session were healthy behaviour habits, vision strategy, body self-image, timeline perspective/ state line exercise, happiness model, and healthy behaviour habit/ vision board. Both groups received online education about obesity, balanced diet, physical activity and hydration from experts consisting of internal medicine specialists, clinical nutrition specialists, and sports medicine specialists. Anthropometric measurements, body composition (using Bioelectric Impedance Analysis), monitoring food intake (using a food record form), monitoring physical activity (using a bouchard activity record), self-empowerment (using a subjective wellbeing questionnaire and healthy behaviour habits satisfaction scale) were compared between the two groups using paired T-test (if the data distribution was normal) and the Mann-Whitney test (if the data distribution was not normal). Phase 3 began with the application of the program to two groups of 30 obese students. Participants were divided into an intervention group and a control group. The intervention group received coaching from a health coach who had received previous training from an internationally certified coach. A health coach accompanied 4 obese students. There were 8 health coaches consisting of family medicine and primary care specialists, internal medicine specialists, sports medicine specialists, faculty study program manager doctors, and coaches who were experienced with coaching approach in the workplace. The coaching session was divided into six meetings every two weeks online via a zoom meeting with the help of a host from the research team. However, the increasing conditions of pandemic restrictions on community activities at this stage, students who completed the program were 23 students in the intervention group and 18 students in the control group. The value of change in the intervention group was significantly greater than the control group in the component of total body fat [-0.9 (-12.9, 0.70) vs 0.0 (-6.9, 3.50), p=0.02 ) and healthy behaviour habit [13.5 ± 11.85 vs. 7.5 ± 8.08, p=0.04]. The value of the change in the healthy behaviour habit satisfaction scale was significantly greater than the control group in the hobby/passion aspect [2(-4.6) vs 1(-2.2), p=0.02], move exercise [2,3 ± 2.11 vs 1.2 ±1.93, p=0.03], sleep rest [2(-6.5) vs 1(-3.2), p=0.01], and spiritual [1( 0.6) vs 0( -1.3), p=0.00]. This method has been proven to be able to be applied and is effective in reducing total body fat and significantly increasing healthy behaviour habits. This coaching method, which is following self-empowerment-based patient-centred care, has been proven to be able to be applied in the university's primary health services. However, support is needed from supportive university policies so that students participating in the program could follow it completely until all the expected output indicators are achieved properly

Abstrak :
Remaja dengan kelebihan berat badan harus diintervensi agar tidak menjadi orang dewasa dengan obesitas. Berkembangnya patient-centered care sebagai upaya pemberdayaan diri dapat menjadi pendekatan terpilih. Dibutuhkan motivasi besar dalam menjalani proses perubahan perilaku. Coaching dilakukan untuk mendampingi klien (coachee) agar mampu mengoptimalkan potensi sehingga memiliki sikap positif, mental yang kuat, dan gaya hidup yang lebih baik. Belum ada penelitian yang mengidentifikasi keberhasilan patient-centered care berbasis pemberdayaan diri dengan metode coaching pada mahasiswa obesitas. Penelitian dilakukan dengan mixed method dalam tiga tahap. Tahap 1 merupakan studi potong lintang untuk mengidentifikasi persepsi mahasiswa terhadap dampak obesitas bagi kesehatan. Kuesioner daring terdiri dari identitas, data antropometri, S-Weight, dan P-Weight. Tahap 2 dilakukan pengembangan model pelayanan dengan cara melaksanakan focus group discussion. Peserta diskusi adalah pakar di tingkat mikro, meso dan makro sistem layanan kesehatan. Tahap 3 menilai kemamputerapan dan efektivitas model layanan yang dikembangkan. Studi dilakukan pada dua kelompok mahasiswa obesitas (usia 18-24 tahun) yang dibagi dalam kelompok intervensi dan kontrol. Pada kedua kelompok diberlakukan model layanan yang sama yaitu pengukuran status antropometrik dan komposisi tubuh, pengisian kuesioner pada awal program, edukasi, dan kembali dilakukan pengukuran status antropometrik dan komposisi tubuh serta pengisian kuesioner pada akhir program. Pada kelompok intervensi ditambahkan uji coba coaching sebanyak 6 sesi setiap dua minggu. Pengukuran awal dan akhir berjarak 3 bulan. Tahap 1 diperoleh 134 mahasiswa obesitas (respons rate 14.1%). Teridentifikasi responden berada pada tahap kontemplasi (35,8%) dan aksi (35,1%) terhadap perubahan perilaku dalam proses menurunkan berat badan. Kesiapan responden bersifat positif (76,9%) pada emosi, dan bersifat negatif pada konsekuensi, dukungan, dan aksi dalam menurunkan berat badan. Tahap 2 dilaksanakan dua tahap FGD terhadap 2 kelompok @ 10 orang. Teridentifikasi bahwa program penurunan berat badan harus diinisiasi dengan membangkitkan rasa kebutuhan untuk lebih sehat dengan berat badan yang ideal. Program harus bersifat personal. Diperlukan dukungan lingkungan seperti ketersediaan makanan sehat dan sarana untuk beraktivitas. Program harus merupakan program yang menimbulkan dukungan terhadap peserta, profesional, dan tersedia di layanan kesehatan. Berdasarkan hal tersebut disusun metode coaching yang sesuai dengan patient-centered care berbasis pemberdayaan diri bagi mahasiswa obesitas dalam program penurunan berat badan. Program terdiri dari 6 sesi coaching. Setiap tema dalam sesi coaching menggunakan langkah SMART dan diberi nama “From Fat to Fit with SMART Program”. Program dilaksanakan dalam waktu 3 bulan. Tema berturut-turut adalah healthy behavior habit, vision strategy, body self-image, timeline perspective/ state line exercise, happiness model, dan healthy behavior habit/ vision board. Kedua kelompok mendapatkan edukasi mengenai dampak obesitas bagi kesehatan, prinsip gizi seimbang, aktivitas fisik dan hidrasi yang sesuai bagi remaja dari para ahli yang terdiri dari spesialis penyakit dalam, spesialis gizi klinik, dan spesialis kedokteran olahraga yang dilakukan secara daring. Pengukuran antropometri, komposisi tubuh (menggunakan Bioelectric Impedance Analysis), pemantauan asupan makanan (menggunakan formulir food record), pemantauan aktivitas fisik (menggunakan bouchard activity record), pemberdayaan diri (menggunakan kuesioner subjective wellbeing dan skala kepuasan healthy behavior habit), dibandingkan antara dua kelompok menggunakan uji T berpasangan (jika distribusi data normal) dan uji Mann-Whitney (jika distribusi data tidak normal). Tahap 3 diawali dengan penerapan program terhadap dua kelompok @ 30 mahasiswa obesitas. Peserta dibagi menjadi kelompok intervensi dan kelompok kontrol. Kelompok intervensi mendapatkan coaching dari health coach yang telah mendapatkan pelatihan sebelumnya dari coach bersertifikat Internasional. Seorang health coach mendampingi 4 mahasiswa obesitas. Health coach berjumlah 8 orang yang terdiri dari dokter spesialis kedokteran keluarga layanan primer, dokter spesialis penyakit dalam, dokter spesialis kedokteran olahraga, dokter pengelola program studi fakultas, dan coach yang berpengalaman dengan pendekatan coaching di tempat kerjanya. Sesi coaching dibagi menjadi enam pertemuan setiap dua minggu secara daring melalui media zoom meeting dengan bantuan host dari tim peneliti. Namun, meningkatnya kondisi PPKM (pemberlakuan pembatasan kegiatan masyarakat) pada tahap ini, mahasiswa yang berhasil menyelesaikan program adalah 23 mahasiswa kelompok intervensi dan 18 mahasiswa kelompok kontrol. Nilai perubahan pada kelompok intervensi secara signifikan lebih besar dibandingkan kelompok kontrol pada komponen total lemak tubuh [-0.9 (-12,9, 0,70) vs 0,0 (-6,9, 3,50), p=0,02) dan healthy behavior habit [13.5 ± 11,85 vs 7,5 ± 8,08, p=0,04]. Nilai perubahan skala kepuasan healthy behavior habit secara signifikan lebih besar dibandingkan kelompok kontrol pada aspek hobby/passion [2(-4,6) vs 1(-2,2), p=0,02], movement exercise [2,3 ± 2,11 vs 1,2 ±1,93, p=0,03], sleep rest [2(-6,5) vs 1(-3,2), p=0,01], dan spiritual [1(0,6) vs 0( -1,3), p=0,00]. ......Adolescents with excess weight should be intervened so as not to become adults with obesity. The development of patient-centred services as an effort to empower oneself could be the approach of choice. It takes great motivation in undergoing the process of behaviour change. Coaching is carried out to assist the client (coachee) to optimize their potential so that they had a positive attitude, strong mentality, and a healthier lifestyle. There has been no research that has identified the success of patient-centred care based on self-empowerment with coaching methods for obese students. Mixed method research were in three stages. Phase 1 was a cross-sectional study to identify students' perceptions of the impact of obesity on health. The online questionnaire consisted of identity, anthropometric data, S-Weight, and P-Weight. Phase 2 was developing a service model by conducting focus group discussions. Discussion participants were experts at the micro, meso, and macro levels of the health care system. Phase 3 assessed the applicability and effectiveness of the developed service model. The study was conducted on two groups of obese college students (aged 18-24 years) in the intervention group and the control group. Both groups were subjected to the same service model, namely an initial physical examination, a questionnaire at the beginning of the service, and education about how to lose weight. A final physical examination and questionnaire were carried out at the end of the program. However, the intervention group was given a coaching method. Initial and final examinations were 3 months apart. Phase 1 obtained 134 obese students (response rate of 14.1%). Respondents identified as being in the contemplation stage (35.8%) and action (35.1%) on behaviour change in the process of losing weight. Respondents' readiness was positive (76.9%) on emotions about losing weight and was negative in terms of consequences, support, and action in losing weight. Phase 2 was carried out in 2 stages of FGD with 2 groups of 10 people. It was identified that a weight loss program should be initiated by generating a sense of the need to be healthier with ideal body weight. Programs should be personal. Environmental support was needed such as the availability of healthy food and facilities for activities. The intervention program should be a program that creates support for participants, professional, and available in health services. Based on this, a coaching method was developed following patient-centred care based on self-empowerment for students with obesity in weight loss programs. The program consisted of 6 coaching sessions. Each session used SMART steps. Each coaching session was themed sequentially and was named “From Fat to Fit with SMART Program”. The program was implemented within 3 months. The successive themes of the coaching session were healthy behaviour habits, vision strategy, body self-image, timeline perspective/ state line exercise, happiness model, and healthy behaviour habit/ vision board. Both groups received online education about obesity, balanced diet, physical activity and hydration from experts consisting of internal medicine specialists, clinical nutrition specialists, and sports medicine specialists. Anthropometric measurements, body composition (using Bioelectric Impedance Analysis), monitoring food intake (using a food record form), monitoring physical activity (using a bouchard activity record), self-empowerment (using a subjective wellbeing questionnaire and healthy behaviour habits satisfaction scale) were compared between the two groups using paired T-test (if the data distribution was normal) and the Mann-Whitney test (if the data distribution was not normal). Phase 3 began with the application of the program to two groups of 30 obese students. Participants were divided into an intervention group and a control group. The intervention group received coaching from a health coach who had received previous training from an internationally certified coach. A health coach accompanied 4 obese students. There were 8 health coaches consisting of family medicine and primary care specialists, internal medicine specialists, sports medicine specialists, faculty study program manager doctors, and coaches who were experienced with coaching approach in the workplace. The coaching session was divided into six meetings every two weeks online via a zoom meeting with the help of a host from the research team. However, the increasing conditions of pandemic restrictions on community activities at this stage, students who completed the program were 23 students in the intervention group and 18 students in the control group. The value of change in the intervention group was significantly greater than the control group in the component of total body fat [-0.9 (-12.9, 0.70) vs 0.0 (-6.9, 3.50), p=0.02 ) and healthy behaviour habit [13.5 ± 11.85 vs. 7.5 ± 8.08, p=0.04]. The value of the change in the healthy behaviour habit satisfaction scale was significantly greater than the control group in the hobby/passion aspect [2(-4.6) vs 1(-2.2), p=0.02], move exercise [2,3 ± 2.11 vs 1.2 ±1.93, p=0.03], sleep rest [2(-6.5) vs 1(-3.2), p=0.01], and spiritual [1( 0.6) vs 0( -1.3), p=0.00]. This method has been proven to be able to be applied and is effective in reducing total body fat and significantly increasing healthy behaviour habits. This coaching method, which is following self-empowerment-based patient-centred care, has been proven to be able to be applied in the university's primary health services. However, support is needed from supportive university policies so that students participating in the program could follow it completely until all the expected output indicators are achieved properly

Abstrak :
Cuka apel merupakan salah satu suplemen makanan yang diklaim dapat digunakan untuk menurunkan berat badan oleh masyarakat Indonesia. Namun, jumlah bukti ilmiah yang mendukung pendapat tersebut masih sedikit. Oleh karena itu, peneliti mengadakan sebuah penelitian dengan metode eksperimental dan berhipotesis bahwa cuka apel dapat menurunkan berat badan tikus strain Sprague Dawley. Dalam penelitian ini digunakan 24 ekor Sprague Dawley dengan berat 190-250 gram sebagai hewan coba. Tikus-tikus ini dibagi menjadi 3 kelompok, yaitu kelompok kontrol (sebagai kontrol negatif), kelompok dietilpropion (sebagai kontrol positif), dan kelompok cuka apel. Ketiga kelompok perlakuan diberi makanan dan minuman dengan jumlah dan jenis yang sama. Selama dua minggu penelitian, dari hari ke hari berat badan dan tingkah laku tikus diamati. Data berat badan sebelum dan sesudah terapi dianalisis secara statistik. Pada akhir penelitian, peneliti tidak menemukan adanya penurunan berat badan pada ketiga kelompok perlakuan, akan tetapi efek sebaliknya terjadi peningkatan berat badan tikus. Hasil analisis statistik menunjukkan adanya perbedaan bermakna antara kelompok kontrol dan kelompok cuka apel (p = 0.012 ). Namun, antara kelompok dietilpropion dan cuka apel tidak ditemukan perbedaan yang bermakna. Hal ini juga ditemukan antara kelompok dietilpropion dan cuka apel. ......Apple cider vinegar is one of food supplements that commonly used to reduce body-weight by Indonesian citizens. But, there is only few scientific proof that supports this opinion. Therefore, researcher held an experimental study and hipotized that apple cider vinegar could reduce the body weight of Sprague Dawley rats. In this study, 24 rats with body weight 190-250 gram are used as experimental animal. These mice were divided into 3 groups, control group (as negative control), diethylpropion group (as positive control group), and apple cider vinegar group. These 3 groups were given the same amount and type of food and drink. For 2 weeks, the body weight and the attitude of mice were observed day by day. The data of mice?s body weight before-and-after treatment were analyzed statistically using SPSS program. In the end of the study, researcher didn?t find any body-weight loss on the 3 groups, but the result of statistical analytic showed that there was significant difference between control group and apple cider vinegar group (p = 0.012). In the other hand, no significant difference found between diethylpropion group and apple cider vinegar group, as well as between dietyhlpropion group and apple cider vinegar group.