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Hasil Pencarian

Ditemukan 2 dokumen yang sesuai dengan query
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Juferdy Kurniawan
Peran Mutasi Regio NS5A Virus Hepatitis C dan SNP IL-28B Pejamu terhadap Keberhasilan Terapi Pegylated Interferon dan Ribavirin pada Pasien Koinfeksi VHC-HIV = The Role of Mutation of Hepatitis C Virus NS5A Region and SNP IL-28B of Host toward The Successfulness of Pegylated Interferon and Ribavirin Treatment Among Patients with HCV-HIV Co-Infection
" HIV coinfection in HCV-infected patients accelerates the course of disease and affects the outcome of Peg-IFN/RBV combination treatment. HCV-HIV coinfected patients are suspected to have HCV mutation in NS5A-ISDR/PKR-BD region that had a role to the successfulness of Peg-IFN/RBV therapy. SNP IL-28B polymorphism is predicted to have an effect on the HCV quasi-species evolution. However, until now the effect of HCV NS5A mutation and SNP IL-28B of the host to the response of treatment is ... "
Depok: Fakultas Kedokteran Universitas Indonesia, 2019
D-Pdf
UI - Disertasi Membership  Universitas Indonesia Library
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The role of hepatitis C virus NS5A region mutation and SNP IL-28B of host to support successful pegylated interferon and ribavirin treatment in patients with HCV-HIV coinfection: a prospective cohort study
" Background: HIV infection in HCV-infected patients accelerates disease progression and reduces the success rate of Peg-IFN/RBV treatment. HCV mutation in NS5A-ISDR/PKR-BD region improved the outcome in HCV monoinfection treated with Peg-IFN/RBV. SNP-IL28B polymorphism is predicted to have an effect on HCV quasispecies evolution. However, the role of NS5A mutation and SNP IL-28B in HIV-HCV coinfection is still unclear. The aim of the study is to determine the role of HCV NS5A-ISDR/PKR-BD mutation and SNP IL-28 ... "
Depok: Universitas Indonesia, 2019
610 UI-IJIM 51:2 (2019)
Artikel Jurnal  Universitas Indonesia Library