Hasil Pencarian  ::  Simpan CSV :: Kembali

Abstrak :

Aktivitas manusia dalam memenuhi kebutuhan hidupnya akan berdampak terhadap lingkungan, termasuk dampak negatif seperti turunnya kualitas lingkungan karena pencemaran timbal. Timbal (Pb) merupakan unsur yang tidak esensial bagi tanaman, namun dapat terserap dan meracuni tanaman. Telah dilakukan penelitian mengenai dampak timbal terhadap profil metabolomik tanaman jahe merah (Zingiber officinale var Rubrum.). Tujuan penelitian untuk mengetahui pengaruh timbal terhadap pertumbuhan dan profil metabolomik rimpang jahe merah. Perlakuan yang diberikan selama 1 bulan adalah PbCl2 50, 100, dan 150 ppm dengan Rancangan Acak Lengkap (RAL) 6 ulangan. Analisis profil metabolomik dilakukan dengan metode HPLC. Analisis statistik menggunakan Principle Component Analysis (PCA) dan Hierarchical Cluster Analysis (HCA). Hasil penelitian menunjukkan pemberian PbCl2 100 ppm dan 150 ppm pada tanaman jahe merah menghasilkan perbedaan yang signifikan terhadap pertumbuhan tinggi tanaman dan gejala toksisitas. Sedangkan perlakuan 50 ppm tidak memberikan pengaruh. Hal tersebut menunjukkan bahwa jahe merah memiliki toleransi terhadap PbCl2 hingga konsentrasi 50 ppm. Hasil PCA dan HCA berupa scatter plot dan dendrogram telah berhasil mengelompokkan tanaman kontrol dengan tanaman perlakuan 50 ppm ke dalam satu klaster, sementara perlakuan 100 ppm membentuk klaster dengan perlakuan 150 ppm. Pemberian PbCl2 lebih dari 100 ppm menghasilkan perbedaan terhadap profil metabolit jahe merah jika dibandingkan dengan kontrol.

---

Human activities meeting their daily needs will impact the environment, including negative impacts such as the decline in the quality of the environment due to lead pollution. Lead is an element that is not essential for plants but can be absorbed and poison plants. Research has been conducted on the impact of lead on the metabolomics profile of red ginger (Zingiber officinale var Rubrum.). This study aimed to determine the effect of lead on the growth and metabolism of red ginger. The treatments were PbCl2 50, 100, and 150 ppm with a Completely Randomized Design with six replications. Metabolic profile analysis was performed using HPLC method. Statistic analysis using multivariate Principle Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA). The research showed that the treatment of 100 and 150 ppm PbCl2 in the sample resulted significant differences in plant height growth and toxicity symptoms. These results show that ginger has a tolerance of PbCl2 at a concentration of 50 ppm. PCA and HCA result have separated control with 50 ppm treatment into one cluster, while 100 ppm treatment forms another cluster with 150 ppm treatment. PbCl2 treatment higher than 100 ppm showed a different metabolite profile compared to the control.

Abstrak :
When John Schilling, an unassuming mid-level accountant, went to work for the Columbia Hospital Corporation, he never expected to become the catalyst for the series of 'whistleblower' cases that ripped through the healthcare industry in the late 1990s. But when he unwittingly discovered that the company was siphoning billions of dollars away from Medicare and stealing from American taxpayers, he was faced with a choice: speak up for what he believed to be right, or remain silent. "Whistleblower" tells the story of Schilling's incredible, harrowing journey from ordinary citizen to federal informant, as he bravely stands up for the truth, treading a dangerous path against corrupt executives, and putting himself in serious personal jeopardy. The book recounts how Schilling, unable to confide in friends or family, allied himself with the FBI and the Justice Department and journeyed into an undercover world in which he learned to wear a wire, and mapped out offices for secret government raids. Suspenseful and provocative, "Whistleblower" chronicles the series of steps that eventually led to the resignation of high-level executives and forced Columbia to return 1.7 billion dollars to the federal government. A compelling account of one man's decision to risk everything for the greater good, this book reveals the personal side of a thankless role that resulted, ultimately, in justice.