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"The objective of this book is to serve as a practical educational resource for clinical magnetic resonance imaging. The bulk of the text is organized along anatomic lines and discusses disease entities commonly encountered in clinical practice. The focus is illustrating and describing the MR appearances of the most commonly imaged disease entities, covering briefly in each area important points relative to imaging techniques then discussing in depth, the clinical MR interpretation. The breadth of clinical MRI is explored. For each subtopic within an anatomic region, clinical cases serve as the backbone for discussion, the most common pathologies affecting each anatomic region being illustrated. The final chapters discuss specifically contrast media and contrast enhanced MRA, two topics worthy of further description due to their present clinical importance. When relevant to diagnosis or essential for understanding, MR physics is discussed, however the reader is referred separately to Runge et al, The Physics of Clinical MR Taught Through Images 2nd Edition (New York: Thieme; 2009) for further elaboration. It is the goal that upon completing this text, the reader will have an appreciation for the complexity, utility, and versatility of MR in clinical imaging and will possess the knowledge essential for interpretation of basic clinical MR "

"Even as magnetic resonance imaging (MRI) has matured into an invaluable diagnostic tool, it has also become a key experimental tool in biological research, where it demonstrates special sensitivity to a plethora of physiological factors, as well as a capacity for use all the way from cellular suspensions to in vivo human studies. In Magnetic Resonance Imaging: Methods and Biologic Applications, leading experts in the use of MRI from both academia and industry explain its basic principles and demonstrate its power to understand biological processes with numerous cutting-edge applications. To illustrate its capability to reveal exquisite anatomical detail, the authors discuss MRI applications to developmental biology, mouse phenotyping, and fiber architecture. MRI can also provide information about organ and tissue function based on endogenous contrast mechanisms. Examples of brain, kidney, and cardiac function are included, as well as applications to neuro- and tumor pathophysiology. In addition, the volume demonstrates the use of exogenous contrast material in functional assessment of the lung, noninvasive evaluation of tissue pH, the imaging of metabolic activity or gene expression that occur on a molecular level, and cellular labeling using superparamagnetic iron oxide contrast agents. Cutting-edge and user-friendly, Magnetic Resonance Imaging: Methods and Biologic Applications illuminates for biological scientists the basic principles of MRI and shows how it can be used successfully to solve important biological problems."