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Abstrak :
Latar Belakang: Kista dentigerous merupakan hasil pembesaran folikel, berasal dari akumulasi cairan antara epitel email tereduksi dan email gigi impaksi. Mayoritas berhubungan dengan gigi yang paling sering impaksi, seperti molar tiga mandibula, kaninus maksila, molar tiga maksila, dan premolar dua mandibula. Setiap elemen gigi impaksi memiliki potensi yang sama mengalami pembentukan Kista Dentigerous. Untuk mencegah hal tersebut maka dibutuhkan perawatan yang tepat dan pencegahan sedini mungkin sehingga kemungkinan morbiditas lebih lanjut dapat dihindari. Berdasarkan tinjauan di atas, penulis ingin mengetahui data terbaru mengenai distribusi dan frekuensi Kista Dentigerous berdasarkan lokasi kelainan di Poli Gigi RSUPN Cipto Mangunkusumo periode 1 November 2002 - 31 Oktober 2008. Tujuan: Penelitian ini bertujuan untuk mengetahui regio yang paling sering mengalami Kista Dentigerous pada pasien Poli Gigi RSUPN Cipto Mangunkusumo periode 1 November 2002 - 31 Oktober 2008. Metode: Penelitian ini berjenis observasi deskriptif dan merupakan studi retrospektif menggunakan data sekunder berasal dari kartu status pasien Poli Gigi RSUPN Cipto Mangunkusumo periode 1 November 2002 - 31 Oktober 2008 yang di dalamnya tercantum biodata, foto panoramik, dan hasil pemeriksaan histopatologis. Hasil: Didapatkan 49 kasus dan 48 elemen gigi. Distribusi dan frekuensi menggunakan tabel dan pie chart yang menggambarkan berapa banyak kista dentigerous berdasarkan lokasi kelainan yang terjadi. Kesimpulan: Distribusi dan frekuensi kista dentigerous paling banyak disebabkan oleh gigi Caninus maksila impaksi dan lokasi kelainan Kista Dentigerous paling banyak terjadi pada regio kaninus - kaninus maksila.

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Backgroud: Dentigerous cyst is a result of folicle swelling, arise from fluid accumulation between the reduced enamel epithelium and the enamel of the impaction tooth. Most often they involve mandibular third molars, maxillary canines, maxillary third molars, and mandibular second premolars. Every single impaction tooth have same potency to grow a Dentigerous Cyst formation. In order to prevent a Dentigerous Cyts formation, we need a certain treatment and prevention must be done as soon as posible so that probability of next morbidity can be prevent. Based on the theory, the author wants to find the latest data about distribution and frequency of Dentigerous Cyst based on causing tooth element and location of cystic lesion in Poli Gigi RSUPN Cipto Mangunkusumo in period of November 1st 2002 - Oktober 31st 2008. Aim: To know the most region that usually have Dentigerous Cyst formation in Poli Gigi RSUPN Cipto Mangunkusumo patients within Period November 1st 2002 - Oktober 31st 2008. Method: The type of this study is descriptive observation - restrospective study by using secondary data from the dental record of Oral and Maxillofacial Surgery Clinic patients in Poli Gigi RSUPN Cipto Mangunkusumo within November 1st 2002 - Oktober 31st 2008 period, which is the content of the dental records is patient`s demographic data, panoramic radiograph, and the result of histopathologic examination. Results: There are 49 cases and involved 48 teeth. Distribution and frequensy use table and pie chart to describe the number of Dentigerous Cyst based on causing tooth element and location of cystic lesion. Conclusions: In this distribution and frequency of Dentigerous Cyst study, the Dentigrous Cyst is usually involve maxillary canine impaction teeth and most often site of Dentigerous Cyst is canine to canine region on maxilla.

Abstrak :
Latar Belakang : Kista dentigerous adalah kista yang berasal dari pemisahan folikel di sekitar gigi yang belum erupsi. Kisaran umur untuk kasus kista dentigerous sangat bervariasi. Menurut Neville, Cawson, dan Regezi kista dentigerous paling sering terjadi pada pasien dengan usia 10-30 tahun (dekade hidup kedua dan ketiga). Sedangkan menurut Fonseca dan Langlais kista ini biasanya terjadi sebelum usia 20 tahun dan lebih sering terjadi pada pria. Berdasarkan tinjauan diatas, penulis ingin mengetahui data terbaru mengenai distribusi Kista Dentigerous berdasarkan usia di Jakarta khususnya di Poli Gigi RSUPN Cipto Mangunkusumo periode 1 November 2002 ? 31 Oktober 2008. Tujuan : Penelitian ini bertujuan untuk mengetahui kisaran usia yang paling sering mengalami kista dentigerous di Poli Gigi RSUPN Cipto Mangunkusumo periode 1 November 2002?31 Oktober 2008. Metode : Penelitian ini berjenis observasi deskriptif dan merupakan studi retrospektif dengan menggunakan data sekunder yang didapat dari kartu status pasien Klinik Bedah Mulut Poli Gigi Rumah Sakit Umum Cipto Mangunkusumo periode 1 November 2002 - 31 Oktober 2008 yang di dalamnya tercantum biodata, hasil foto panoramik serta hasil diagnosis patologi anatomi. Hasil : frekuensi distribusi menggunakan tabel dan pie chart yang menggambarkan berapa banyak kista dentigerous menurut usia yang terjadi. Kesimpulan : Distribusi dan frekuensi kista dentigerous paling banyak terjadi pada kelompok umur 21-30 tahun.

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Background : Dentigerous Cyst is a cyst that arise from follicle separation that surrounding an unerupted tooth. The age range of dentigerous cyst is variant. According to Neville, Cawson,and Regezi, dentigerous cyst occur most frequent in patient age 10-30 years old (second and third decade of life). While according to Fonseca and Langlais this cyst usually occur before age of 20 and occur more frequent on men. Reposing the observation above, the author want to discover the latest data about distribution of dentigerous cyst based on age in Jakarta, especially in Poli Gigi RSUPN Cipto Mangunkusumo period 1 November 2002 - 31 October 2008. Purpose : to find age range of dentigerous cyst that occur most frequent in Poli Gigi RSUPN Cipto Mangunkusumo periode 1 November 2002 - 31 October 2008. Method : The type of this study is descriptive observation - retrospective by using secondary data from medical record of the oral and maxillofacial surgery patients in Poli Gigi Rumah Sakit Umum Cipto Mangunkusumo within period of time of 1 November 2002 - 31 October 2008, which is the content of the medical records is patient?s data, panoramic radiograph results, and also pathology anatomy results. Results : Distribution and frequency use table and pie chart and also bar chart to describe how many dentigerous cyst that occur based on sex. Conclusion : Distribustion and frequency of dentigerous cyst occur most frequent on group of age 21-30 years old.

Abstrak :
Latar Belakang : Kista dentigerous merupakan kista yang berasal dari separasi bentuk folikel sekitar gigi yang belum erupsi atau impaksi. Biasanya kista ini terjadi sebelum usia 20 tahun dan memiliki predileksi pada pria. Banyak studi yang mengatakan pula bahwa kista dentigerous lebih sering terjadi pada pria dibandingkan wanita. Beberapa laporan-laporan diatas telah memberikan evaluasi yang membandingkan frekuensi dan distribusi kista dentigerous dari beberapa populasi grup yang berbeda. Oleh karena itu, penulis ingin mengetahui data terbaru tentang distribusi Kista Dentigerous berdasarkan jenis kelamin di Jakarta khususnya di Poli Gigi Rumah Sakit Umum Pusat Nasional Cipto Mangunkusumo untuk kasus-kasus yang terdapat pada periode 1 November 2002 - 31 Oktober 2008. Tujuan : Penelitian ini bertujuan untuk mengetahui apakah terdapat predileksi jenis kelamin pada kasus kista dentigerous di Poli Gigi RSUPN Cipto Mangunkusumo untuk kasus-kasus yang terdapat pada periode 1 November 2002 - 31 Oktober 2008. Metode : Penelitian ini berjenis observasi deskriptif dan merupakan studi retrospektif dengan menggunakan data sekunder yang didapat dari kartu status pasien Bedah Mulut Poli Gigi Rumah Sakit Umum Cipto Mangunkusumo periode 1 November 2002 - 31 Oktober 2008 yang di dalamnya tercantum biodata, hasil foto panoramik serta hasil diagnosis patologi anatomi. Hasil : frekuensi distribusi menggunakan tabel dan pie serta bar chart yang menggambarkan berapa banyak kista dentigerous menurut jenis kelamin yang terjadi. Kesimpulan : Frekuensi distribusi kista dentigerous pada lakilaki lebih tinggi dibandingkan perempuan.

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Background: Dentigerous cyst is a cyst that arise from separation of follicle formation surrounding the unerupted or impaction tooth. Usually this cyst form before age of 20 and have a predilection on men. Many researchs state that dentigerous cysts occur more frequently on men than women. Few of reports above have given an evaluations comparing frequencies and distributions of dentigerous cysts in a couple of different groups. Therefore, the author want to find the latest data about the distribution and frequency of dentigerous cyst based on sex in Poli Gigi Rumah Sakit Umum Pusat Nasional Cipto Mangunkusumo in cases period of 1 November 2002 - 31 October 2008. Purpose : To find whether there is a sex predilection on dentigerous cyst cases in Poli Gigi RSUPN Cipto Mangunkusumo in cases period of 1 November 2002 ? 31 October 2008. Method : The type of this study is descriptive observation - retrospective by using secondary data from medical record of the oral and maxillofacial surgery patients in Poli Gigi Rumah Sakit Umum Cipto Mangunkusumo within period of time of 1 November 2002 - 31 Oktober 2008, which is the content of the medical records is patient`s data, panoramic radiograph results, and also pathology anatomy results. Results : Distribution and frequency use table and pie chart and also bar chart to describe how many dentigerous cyst that occur based on sex. Conclusions : Dentigerous cyst cases have a higher distribution and frequency on men than a women.

Abstrak :
Latar Belakang: Kista dan tumor odontogenik merupakan aspek yang sering dibahas dan cukup penting dalam bidang bedah maupun patologi oral dan maksilofasial. Secara radiografi gambaran kista dentigerous, odontogenic keratocyst (OKC), dan ameloblastoma unikistik memiliki kemiripan berupa lesi radiolusen unilocular. Pada hasil pemeriksaan histopatologi dengan pewarnaaan hematoksilin eosin ketiga lesi ini dapat dibedakan, namun banyak ahli patologi yang mengalami misdiagnosa dikarenakan kemiripannya. Calretinin merupakan protein pengikat kalsium yang sudah banyak digunakan untuk penanda keganasan pada jaringan tubuh manusia, dikarenakan perannya dalam apoptosis sel yang menyebabkan terjadinya proliferasi sel. Tujuan: untuk melihat dan membandingkan ekspresi Calretinin pada kista dentigerous, OKC, dan ameloblastoma unikistik. Metode: 34 blok parafin kista dentigerous, OKC dan ameloblastoma unikistik didapatkan secara consecutive sampling dari data rekam medik di Divisi Bedah Mulut RSCM yang telah dilakukan konfirmasi hasil histopatologinya di Departemen Patologi Anatomi RSCM selama periode 2015- 2019. Seluruh sampel dilakukan pemeriksaan imunohistokimia menggunakan antibodi Calretinin. Hasil: didapatkan 13 sampel kista dentigerous (38,2%), 6 sampel OKC(17,6%), dan 15 sampel ameloblastoma unikistik(44,2%). Yang terintepretasi positif Calretinin sebanyak 1 sampel kista dentigerous (2,9%) dan 11 sampel ameloblastoma unikistik(32,3%), namun tidak ada sampel OKC (0) yang terintepreatsi positif. Secara statistik dengan uji chi-square didapati hasil berbeda bermakna(p=0,001) dengan odd ratio (OR) sebesar 49,5 antara kelompok ameloblastoma unikistik dan kelompok bukan amleoblastoma unikistik. Kesimpulan: Calretinin terekspresi pada kista dentigerous dan ameloblastoma unikistik dengan persentase yang berbeda, namun tidak pada OKC. Calretinin dapat dijadikan penanda spesifik untuk ameloblastoma unikistik. ......Background: Odontogenic cysts and tumors are aspects that often discussed and quite important in the field of either oromaxillofacial surgery or pathology. Radiographically, the dentigerous cyst, odontogenic keratocyst (OKC), and unicystic ameloblastoma have a similar appearance in the form of unilocular radiolucent lesions. As a results of histopathological examination with hematoxylin eosin staining, these three lesions can be distinguished, however, many pathologists are misdiagnosed because of their similarity. Calretinin is a calcium binding protein that has been widely used for markers of malignancy in human tissues, due to its role in cell apoptosis which causes cell proliferation. Objective: This study aims to observe and compare Calretinin expression in dentigerous cysts, OKC, and unicystic ameloblastoma. Methods: 34 paraffin blocks of dentigerous cysts, OKC and unicystic ameloblastoma were obtained by consecutive sampling from medical record data in RSCM, Oral Surgery Division which had confirmed histopathological results at the Department of Anatomical Pathology RSCM during the period 2015-2019. All samples were subjected to immunohistochemical staning using Calretinin antibodies. Results: 13 samples of dentigerous cysts, 6 samples of OKC, and 15 samples of unicystic ameloblastoma were obtained. The positive interpretation of Calretinin was 1 sample of dentigerous cyst and 11 samples of unicystic ameloblastoma. Conclusion: Calretinin was expressed in dentigerous cysts and unicystic ameloblastoma with different percentages, but not in OKC. Calretinin can be used as a marker for unicystic ameloblastoma

Abstrak :
The purpose of the study to seek the differences of cell proliferation index among dentigerous cyst. dentigerous with ameloblastoma and ameloblastoma plexiform. This study utilized retrospective methode, which was achieved by collecting data from medical record in oral surgery clinic. Cipto Mangunkusumo Hospital and Pathology Anatomy Laboratory at Faculty of Medicine University of Indonesia from January 1998 to April 2002. Histological examination were prepared from 34 samples; consist of 15 dentigerous cysts, 11 ameloblastoma and 8 dentigerous cyst which arise with ameloblasroma. ln each case, intra-nuclear AgNOR dots were counted in 100 consecutive basal nuclei. Statistic analysis using ANOVA show the difference among study objects (p<0.05). AgNOR an ameloblastoma is significantly higer than in dentigerous cyst. The differences may indicate the variation of metabolic, proliferation of transcriptional activities of the cell. The study found the difference of AgNOR count in cell proliferation index among dentigerous cyst, dentigerous cyst which arise with ameloblastoma and ameloblastoma. The finding can be used to determine the diagnoses in doubtfull cases where dentigerous and ameloblastoma cannot be distinguished clinically and pathologically.