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"Latar Belakang : Cedera kranioserebral ada 2, yaitu cedera primer dan sekunder. PatofisioIogi cedera sekunder yang kompleks menyebabkan perlunya parameter tambahan untuk menilai perburukan klinis penderita cedera kranioserebral. Pada penelitian terdahulu didapat suatu hubungan antara kadar interleukin 6 serum dengan keluaran cedera kranioserebral. Dimana semakin tinggi kadar 11-6 akan semakin buruk keluaran cedera kranioserebral. Dengan melihat hal ini kami melakukan penelitian untuk mengeksplorasi hubungan antara kadar M-6 dengan penderita ceders kranioserebral.Objektif : Mengetahui peranan IL-6 pada kondisi klinis penderita cedera kranioserebral 5KG 6-12Desain dan Metode: Observasional dengan repeated measurement design sesuai dengan kriteria seleksi dan dieksplorasi apakah terdapat hubungan IL-6 dengan SKG hari 1,3,7 atau mortalitas.Hasil : 63 penderita cedera kranioserebral SKG 6-12 dalarn 24 jam dari onset. Semua pasien dilakukan pemeriksaan IL-6 serum dan DPL rutin, Nilai rerata IL-6 tertinggi adalah pada SKG 6 508,938 ± 98,125 dan nilai rerata terendah adalah 11,725 ± 8,441. Dengan uji kai kuadarat didapati hubungan semakin tinggi nilai IL-6 semakin rendah nilai SKG (p<0,0001). Dengan uji kai kuadrat juga didapati semakin tinggi kadar M-6 semakin tinggi mortalitas (p<0,002).Kesimpulan : IL-6 dapat dijadikan salah satu prediktor keluaran penderita cedera kranioserebral.

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Background : Traumatic brain Injury (TBI) is divided in to primary and secondary injury. Complexities of the pathophysiology of secondary brain injury made additional parameters in to evaluation for observed the worsening effect of those mechanisms. In the current study there is a correlation between IL 6 serum concentration and the outcome of TBI. The higher 1L6 would be markedly worsening outcome. Based on this concept, we make the research to explore the correlation between IL 6 concentration and TBI patient.

Objective: To explore the rule of IL 6 on the worsening clinical condition of the TBI patient GCS 6-8 and GCS 9-12.

Design and methods: Observational study with repeated measurement design due to selection criteria and being explored whether any correlation between IL 6 and GCS on day 1,3,7 or mortality.

Results: 63 TBI patients with GCS 6-12 and the onset are 24 hours enrolled to this study. All the patient had IL 6 serum and routine blood test. The highest mean of IL 6 is 508,938 + on GCS 6 and the lowest mean is 11,725 + 8,441 on GCS 12. Result of the chi square test showed there was correlation the higher IL 6 and the lower GCS (p<0,0001). The other analyzed the chi square test showed there were also correlation between the higher IL 6 and mortality (p<0,002).

Conclusion : IL- 6 could be used as one of TBI outcome predictor."

"ABSTRAKPenelitian ini berusaha mengetahui peran faktor keluarga, melalui tingkat family functioning dan family hardiness terhadap keterkaitan antara paparan kejadian traumatik (traumatic exposure) dengan posttraumatic growth melalui analisis moderated-mediation pada penyintas bencana alam gempa bumi dan likuifaksi di PASIGALA. Partisipan yang didapatkan adalah 122 orang penyintas berusia 17-35 tahun (M = 21.541, SD = 4.936) yang merupakan penyintas likuifaksi PASIGALA secara primer atau langsung. Hasil yang didapatkan menunjukkan bahwa tingkat family hardiness sedang hingga tinggi memberikan efek positif terhadap keberfungsian keluarga sehingga menjadi fungsional meskipun mengalami beberapa paparan kejadian traumatik. Namun, keberfungsian keluarga yang diperkuat oleh family hardiness tidak menjadikan individu dapat mencapai posttraumatic growth yang lebih tinggi meskipun family hardiness berperan penting dalam menjadikan keluarga berfungsi dengan baik. Secara praktis, hasil mengarahkan agar program trauma healing yang mendukung tercapainya posttraumatic growth sebaiknya berfokus pada aspek personal penyintas, seperti perbedaan paparan kejadian yang dialami. Tetapi, program untuk membantu keluarga dapat berfungsi dengan baik kembali (healthy) setelah melalui krisis kebencanaan dapat dilakukan dengan berfokus pada membantu keluarga membentuk karakter yang hardy.

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ABSTRACTThis study discusses the role of the family, through family functioning and family hardiness on the relationship between the reporting of traumatic events (traumatic exposure) with posttraumatic growth through moderated-mediation analysis in survivors of Earthquake and Liquefaction disaster in PASIGALA. Participants obtained were 122 individuals (17-35 years old, M = 21.541, SD = 4.936) who were primary survivors of PASIGALA liquefaction. The results obtained indicate that the mean and higher level of family hardiness have a positive effect on moderating the negative effect of traumatic exposure to the family functioning. However, family functioning supported by family hardiness does not make individuals able to achieve higher post-traumatic growth indirectly although it is an important factor for helping family to function well. These lead to encouraging social workers in helping survivors, to focus on their personal aspect, such as degree of traumatic exposures. However, helping family as a whole to be well-functioning after disaster also could be conducted, by focusing on building characteristics of hardy family."