Ditemukan 4 dokumen yang sesuai dengan query
"
Toxicogenomics is the integration of genomics to toxicology. This technology is a powerful tool for collecting information from a large number of biological samples simultaneously and thus it is very useful for large-scale screening of potential toxicants.
Toxicogenomics : a powerful tool for toxicity assessment provides up-to-date state-of-the-art information presented by the recognized experts, and is therefore an authoritative source of current knowledge in this field of research. The potential link between toxicology, genetics and human ...
"
Chichester, West Sussex, U.K.: Wiley & Sons, 2008
e20395847
eBooks Universitas Indonesia Library
Boverhof, Darrell R., editor
"
This book provides a timely overview of toxicogenomics, with special emphasis on the practical applications of this technology to the risk assessment process. Introductory sections are followed by a series of chapters highlighting practical and systematic applications of toxicogenomics in informing the risk assessment process, including the areas of mutagenicity, carcinogenicity, endocrine toxicity, organ, specific toxicity, population monitoring, and ecotoxicology. The book concludes with approaches for the integration of this technology in safety evaluation studies, ...
"
Hoboken, New Jersey: John Wiley & Sons, 2011
e20410878
eBooks Universitas Indonesia Library
"
This book addresses all the current, up-to-date developments in this scientific discipline. Liver is the chief metabolizing site in the body, and thus, it is a major target organ for drug and chemical toxicity. Therefore, hepatotoxicity is an important endpoint in the safety evaluation of drugs and chemicals.
Contributions from leading investigators in hepatotoxicity research address current developments in this scientific discipline and discuss use of current cutting edge technology such as microarrays in hepatotoxicity thus ...
"
Chichester, West Sussex, England: John Wiley & Sons, 2007
e20395854
eBooks Universitas Indonesia Library
"
This book examines genotoxic impurities and their impact on the pharmaceutical industry.Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately control genotoxic impurities, thus aiding the reader to develop effective control measures. An opening section covers the development of guidelines and the threshold of toxicological concern (TTC) and is followed byasection on safety aspects, including safety tests in vivo and ...
"
Hoboken: John Wiley & Sons, 2010
e20393941
eBooks Universitas Indonesia Library
