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Abstrak :
Skin cancer is a malignant growth on the skin caused by many factors. The most common skin cancers are Basal Cell Cancer (BCC) and Squamous Cell Cancer (SCC). This research uses a discriminant analysis to classify some tissues of skin cancer based on criterion number of independent variables. An independent variable is variation of excitation light sources (LED lamp), filters, and sensors to measure Autofluorescence Intensity (IAF) of visible light to near infrared (VIS/NIR) ratio of paraffin embedded tissue biopsy from BCC, SCC, and Lipoma. From the result of discriminant analysis, it is known that the discriminant function is determined by 4 (four) independent variables i.e., Blue LED-Red Filter, Blue LED-Yellow Filter, UV LED-Blue Filter, and UV LED-Yellow Filter. The accuracy of discriminant in classifying the analysis of three skin cancer tissues is 100 %.

Abstrak :
Skin cancer as the most common cancer diagnosis tend to be increasing. This condition is a particularly significant issue in developed countries. This study aimed to describe the clinical features, histopathological features, complications, and early surgical treatment outcomes of skin cancer in Can Tho Oncology Hospital from 2014 to 2015. This descriptive prospective study involved all patients with non-melanoma skin cancer that were examined and treated at Can Tho Oncology Hospital from July 2014 to March 2015. There were 78 cases selected. Skin cancer was found to be more common among older patients. The prevalence of basal cell carcinoma was found higher than squamous cell carcinoma with percentage worth 76.9% and 23.1% respectively. Worth 73.1% of all the patients in the study underwent surgery with wide resection and reconstruction. In this study, most patients were the elderly. The basal cell carcinoma was the most common. The main treatment was surgery with wide resection and reconstruction. The complication was rare 1.3% with skin flap necrosis.

Kanker kulit, diagnosis kanker paling umum, cenderung mengalami peningkatan. Kondisi ini secara khusus merupakan isu penting di negara-negara maju. Penelitian ini bertujuan untuk mendeskripsikan fitur klinis, fitur hispatologis, komplikasi dan hasil pengobatan bedah awal kanker kulit di Rumah Sakit Onkologi Can Tho dari tahun 2014 sampai 2015. Penelitian deskriptif prospektif ini melibatkan seluruh pasien dengan kanker kulit nonmelanoma yang diuji dan diobati di Rumah Sakit Onkologi Can Tho dari Juli 2014 sampai Maret 2015. Terdapat 78 kasus terpilih. Kanker kulit ditemukan lebih umum pada pasien yang lebih tua. Prevalensi karsinoma sel basal ditemukan lebih tinggi dibandingkan karsinoma sel skuamosa dengan persentase masing-masing 76,9% dan 23,1%. Sebesar 73,1% dari seluruh pasien dalam penelitian ini menjalani bedah dengan rekonstruksi dan reseksi yang lebar. Dalam penelitian ini, sebagian besar pasien adalah lanjut usia. Karsinoma sel basal adalah yang paling umum. Pengobatan utama adalah bedah dengan rekonstruksi dan reseksi yang lebar. Komplikasi jarang terjadi 1,3% dengan nekrosis lipatan kulit.

Abstrak :
Kanker kulit di Indonesia menempati urutan ketiga teratas dengan persentase sebesar 15,1% dari total 13 kanker yang paling umum diderita di Indonesia. Kanker kulit disebabkan oleh radiasi sinar ultraviolet yang merusak DNA di dalam sel kulit manusia. Penggunaan tabir surya setiap hari dapat meminimalkan probabilitas terjadinya kanker kulit. Efisiensi tabir surya dinyatakan dalam nilai SPF. Penggunaan bahan pelindung matahari dari bahan alam dipercaya lebih aman dan tidak banyak memiliki efek samping. Salah satu sumber hutan Indonesia yang berpotensi mengandung SPF alami adalah lemak tengkawang. kehadiran senyawa fenolik pada lignin memiliki kemampuan pertahanan terhadap sinar UV, sehingga lignin disebut sebagai bahan penahan sinar UV alami. Penelitian ini mengevaluasi penambahan lignin yang mengandung fenolik untuk meningkatkan kandungan SPF pada lemak tengkawang. Pada penelitian ini lemak tengkawang mengalami tahap degumming, netralisasi dan pemucatan. Hasil penelitian menunjukkan bahwa nilai SPF pada lemak tengkawang bernilai 7,052 dan penambahan l0% (b/b) lignin berhasil meningkat nilai tersebut menjadi 53, 549. ......Skin cancer in Indonesia ranks the top three with a percentage of 15,1% of 13 most common cancers suffered in Indonesia. Skin cancer is caused by ultraviolet radiation with ability to damages human DNA skin cell. The use of sunscreen every day can decrease the probability of skin cancer. The efficiency of sunscreen is expressed in SPF values. The use of sun protection agent from natural materials is believed to be more safe and less side effects. One of Indonesia's forest resources that potentialy contain natural sun protection factor is illipe butter. The presence of phenolic compounds in lignin has the ability to defend against UV rays, so lignin can be called as natural UV retaining agent. This study will evaluate the addition of lignin which contain phenolic that has the ability to increase the SPF value in illipe butter. In this research, the treatment of illipe butter will consist of degumming, neutralization and bleaching. The result showed that the SPF value of illipe butter is 7,052 and the addition of 10% (w/w) lignin succeded in increasing SPF value into 53,549.

Abstrak :
Penelitian ini menyajikan ekstraksi fitur citra dermatoskopik untuk diagnosis kanker kulit melanoma berdasarkan asymmetry, border irregularity, color variation, dan diameter (ABCD). Fitur ABCD adalah informasi yang penting berdasarkan analisis morfologi lesi citra dermatoskopik. Fitur tersebut digunakan dalam perhitungan Total Dermatoscopic Value (TDV) untuk diagnosis kanker kulit melanoma. Fitur asymmetry terdiri dari informasi asimetri dan indeks perpanjangan luka. Fitur border irregularity terdiri dari informasi indeks compactness, dimensi fraktal, edge abruptness, dan transisi pigmentasi dari lesi. Warna fitur homogenitas terdiri dari informasi homogenitas warna dan korelasi antara fotometri dan geometri lesi. Ekstraksi diameter adalah diameter lesi. Ada tiga diagnosa yang digunakan pada penelitian ini yaitu melanoma, diduga melanoma, dan benign skin lesion. Percobaan ini menggunakan 30 sampel dari lesi citra dermatoskopik kanker kulit melanoma yang mencurigakan. Berdasarkan percobaan, akurasi dari sistem ini adalah 85% dan terdapat empat diagnosa palsu dari 30 sampel.

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Abstract
This research present asymmetry, border irregularity, color variation, and diameter (ABCD) feature extraction of image dermatoscopic for melanoma skin cancer diagnosis. ABCD feature is the important information based on morphology analysis of image dermatoscopic lesion. ABCD feature is used to calculate Total Dermatoscopic Value (TDV) for melanoma skin cancer diagnosis. Asymmetry feature consist information of asymmetry and lengthening index of the lesion. Border irregularity feature consist information of compactness index, fractal dimension, edge abruptness, and pigmentation transition from the lesion. Color homogeneity feature consist information of color homogeneity and the correlation between photometry and geometry of the lesion. Diameter extraction is diameter of the lesion. There are three diagnosis that is used on this research i.e. melanoma, suspicious, and benign skin lesion. The experiment uses 30 samples of image dermatoscopic lesion that is suspicious melanoma skin cancer. Based on the experiment, the accuracy of the system is 85% that there are four false diagnoses of 30 samples.

Abstrak :
Kanker kulit merupakan penyakit yang disebabkan oleh akumulasi perubahan molekul genetik maupun epigenetik pada jaringan kulit. Salah satu tipe kanker kulit yang bersifat invasif adalah karsinoma sel skuamosa KSS . Keuntungan diketahuinya lesi prakanker sel skuamosa secara lebih dini mampu mencegah lesi tersebut berkembang menjadi KSS invasif sehingga dapat meningkatkan efek terapiyang diberikan. 5-FU merupakan senyawa antimetabolit yang bekerja sebagai antagonis pirimidin pada molekul DNA dan RNA yang menginduksi apoptosis pada sel. Penelitian ini bertujuan untuk mengetahui efek apoptosis dan hambatan proliferasi melalui ekspresi protein caspase-3 dan Ki67 pada lesi prakanker sel skuamosa kulit mencit yang diinduksi DMBA/croton oil dengan perlakuan krim 5-FU dan imiquimod 5 topikal. Krim 5-FU yang diuji terdiri atas konsentrasi 1 , 2 , dan 5 . Analisis ekspresi protein dilakukan dengan metode imunohistokimia. Pada induksi karsinogenesis diketahui bahwa papilloma mulai muncul pada minggu ke-5 atau ke-6 setelah perlakuan DMBA/croton oil. Hasil pemberian terapi 5-FU selama 4 minggu minggu ke-10 sd minggu ke-14 menunjukkan adanya penurunan pada jumlah dan volume tumor p0.05 , sedangkan ekspresi Ki67 terendah pada pemberian5-FU 2 dan 5 p

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Skin cancer is a multifactorial disease caused by accumulation of alteration in genetic and is squamous cell carcinoma SCC . The advantage of early detection for squamous cell pracancerous prevent those lesion may progress to invasive SCC and increase the effect of therapy. 5 FU is an antimetabollite compound as aDNA RNA pirimidine antagonist molecule induce cell apoptotic. The main objective of this research is to know the apoptotic effect and proliferative inhibition through caspase 3 and Ki67 expepigenetic molecule on skin tissues. One of the type of skin cancer that can be invasiveression on mice skin squamous cell precancerous induced by DMBA croton oil treated using 5 FU topically. This research assess three differences concentration of 5 FU include 1 , 2 , and 5 . The expression of caspase 3 and Ki67 were analyzed using immunohistochemistry methods. Carsinogenesis induction seem papiloma growth at 5 or 6 weeks after DMBA croton oils treatments. Result of 5 FU treatment 4 weeks week 10 week 14 showed that decrease of cumulative number and volume of papiloma p0.05 ,and the lowest Ki67 expression in 5 FU 2 and 5 application p

Abstrak :
This book fills that gap by providing an overview of indoor tanning, reasons for its popularity, its risks including skin cancers, and the public health context surrounding the behavior. We have invited some of the preeminent experts in the field to summarize the existing scientific literature for each of the chapters. Shedding light on indoor tanning is an up-to-date and comprehensive book that provides a unique and essential overview of the most significant current issues related to indoor tanning for scientists, educators, students, clinicians, and the general public interested in dermatology, aesthetic trends, skin care, and skin cancer.