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"Rotavirus causes 25?55% of all hospital admissions for diarrhea and approximately 611.000 deaths every year in developing countries. Clinically, it is not possible to recognize the diarrhea caused by rotavirus and other infections. To know a causative agent of rotavirus gastroenteritis, availability of an accurate diagnosis assay is necessary. Therefore, we developed real time RT-PCR assay (rRT-PCR) assay for confirmation of infections of Group A or C rotaviruses simultaneously. A total of 54 stool samples obtained from pediatric patients (< 5 years old) was used in this study. Allsamples were tested for Group A rotavirus by Serological rapid test. Result of serological rapid test was compared with rRT-PCR assay to obtain the test accuracies of both assays. Result of this study showed that rates of positive testing for Group A rotavirus by serological rapid test and the rRT-PCR assay were 22.22% and 18.50%, espectively. Forty-two serology-negative specimens for Group A rotavirus were also PCR negative (100% specificity). Two serology-positive specimens for Group A rotavirus was rRT-PCR negative (confirmed by electrophoresis gel); therefore, rRT-PCR assayrepresents the decrease of 3.70% in the number of specimens that are positive for Group A rotavirus. For Group C rotavirus, all tested samples were no rRT-PCR positive and the results need to be confirmed in the future. "

"ABSTRAKLatar belakang. Di Sumatera Barat didapatkan peningkatan kasus infeksi virus dengue. Beberapa kasus juga terjadi pada bayi ≤ 1 tahun. Bayi mempunyai karakteristik klinik yang unik dan tidak banyak penelitian mengenai hal ini di Indonesia.Tujuan. Mengetahui profil klinis, laboratorium dan serologi infeksi virus dengue pada bayi yang di rawat di RSUP Dr. M Djamil Padang dari tahun 2012-2014Metode. Penelitian cross-sectional, menggunakan data rekam medic bayi IVD yang dirawat di RSUP Dr M Djamil Padang dari 1 Januari 2012-31 Desember 2014. Data yang dianalisis mencakup usia, jenis kelamin, hari demam saat diagnosis, suhu, demam, batuk, diare, muntah, kejang, hematemesis, melena, syok, ptekie, and hepatomegali.Hasil. 12 bayi digunakan sebagai sampel. Usia termuda bayi DBD adalah 3 bulan, dengan usia terbanyak 5 bulan (5 bayi). Muntah merupakan gejala tambahan yang paling banyak ditemukan (9 dari 12 bayi), diikuti oleh ptekie dan syok (masing-masing 6 bayi), serta batuk (5 bayi). 8 dari 12 bayi menunjukkan infeksi primerKesimpulan. Rerata usia dan kelompok usia terbanyak setara dengan penelitian sebelumnya.

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ABSTRACTBackground. In West Sumatera, cases of dengue virus infection is increasing. Some occur in infants below 1 year old. Babies has unique clinical characteristic and only few researchs take place on this subject in Indonesia.Objection. Describing the clinical, laboratory, and serology profile of dengue virus infection in infants taken care at Dr. M Djamil Hospital in Padang, West Sumatera from 2012 to 2014.Methods. This is a cross-sectional study based on medical record data on baby who were treated in Dr M Djamil Padang from January 1st, 2012 to December 31st, 2014. The data analyzed were age, gender, fever duration at diagnosis, body temperature, fever, cough, diarrhea, vomit, seizure, hematemesis, melena, shock, ptekie, and hepatomegaly.Results. 12 babies were collected as sample. Youngest baby had DHF was 3 months old, while the oldest was 5 months old (5 infants). Vomit is the additional symptom most commonly found (9 of 12 infants), followed by ptekie and shock (6 babies each), and cough (5 infants). Eight of 12 infants showed primary infection.Conclusion. The mean for age and mode for age group were similar to previous studies"

"ABSTRAKLatar belakang: Frambusia atau yaws merupakan penyakit akibat infeksi Treponema pallidum subspecies pertenue yang menahun dan terutama mengenai kulit serta tulang. Penegakkan diagnosis berdasarkan klinis dan serologis. Program temuan kasus frambusia didasarkan atas temuan klinis menurut World Health Organization WHO , kemungkinan terdapat frambusia tanpa lesi klinis yang tidak terdiagnosis masih belum dapat disingkirkan. Belum ada penelitian proporsi di suatu desa yang dinyatakan endemis. Tujuan: Mengetahui proporsi kasus frambusia berdasarkan kriteria klinis WHO dan pemeriksaan serologis di desa Sei Berombang pada anak usia 1-12 tahun periode 22-27 Agustus 2016. Metode: Studi potong lintang ini dilakukan pada tanggal 22-27 Agustus 2016 di desa Sei Berombang, Sumatera Utara. Pemilihan sampel dilakukan secara consecutive sampling. Subjek kemudian dilakukan anamnesis, pemeriksaan fisis, dan pemeriksaan rapid diagnostic test RDT . Hasil : Didapatkan total 129 subjek dengan median usia 9 tahun termuda 1 tahun dan tertua 12 tahun . Sebanyak 14 anak dengan lesi klinis suspek frambusia, sedangkan 4 anak dengan RDT yang positif. Hanya 3 anak dari RDT yang positif memiliki temuan klinis. Lesi klinis suspek frambusia yang paling banyak ditemukan adalah makula hipopigmentasi dan skar atrofik, sedangkan lokasi tersering adalah tungkai bawah. Simpulan: Ditemukan proporsi suspek frambusia berdasarkan klinis adalah 10,85 , sedangkan proporsi frambusia konfirmasi berdasarkan klinis dan serologis adalah 2,33 . Dua subjek didiagnosis frambusia laten, sedangkan satu subjek didiagnosis sebagai frambusia primer. Kata kunci: frambusia, proporsi, anak

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ABSTRACTBackground Yaws is a chronic infectious disease caused by Treponema pallidum subspecies pertenue, mainly affecting skin and bone. Diagnosis of yaws is based on clinical manifestation and serologic test. According to WHO, yaws detection program is focused on clinical manifestation. Thus, it is possible that latent yaws without any clinical manifestation is still under diagnosed. Until recently, there is no proportion study performed in remote endemic village.Objective To determine the proportion of yaws based on WHO clinical criteria and serologic test in children age 1 12 years old in Sei Berombang village.Methods This cross sectional study was conducted on 22nd 27th August 2016 in Sei Berombang village, North Sumatra. We recruited the subjects consecutively and performed anamnesis, clinical examination, and rapid diagnostic test RDT .Results A total of 129 subjects were examined with median age of 9 years old 1 12 years old . Yaws was suspected in 14 subjects, but only 4 subjects were reactive to RDT. Three subjects had clinical manifestation and RDT reactive. Hypopigmentation patch and atrophic scar were the most common clinical findings in this study. Most lesions were found in lower extremities. Conclusion Proportion of suspected yaws based on clinical manifestation is 10,85 in this study. Proportion of confirmed yaws based on clinical manifestation and serology is 2,33 . Two subjects diagnosed with latent yaws and one subject was diagnosed with primary yaws. "

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