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"Pengelolaan sediaan farmasi di Puskesmas meliputi pengendalian persediaan, penggunaan, dan masa kedaluwarsa obatnya. Obat kedaluwarsa atau rusak tidak diperkenankan untuk diberikan kepada pasien, sebab dapat menyebabkan efek toksik yang membahayakan jika dikonsumsi. Oleh sebab itu pemantauan kedaluwarsa obat harus dilakukan untuk meminimalkan hal yang tidak diinginkan. Tujuan monitoring kedaluwarsa obat ditujuan untuk mendata ketersediaan obat yang kedaluwarsa pada tahun 2022 dan menindaklanjuti obat-obat yang kedaluwarsa di Puskesmas Kecamatan Kramat Jati. Monitoring dilakukan dengan merekapitulasi stock opname persediaan obat setiap bulannya untuk dievaluasi. Hasil monitoring pada tahun 2022 didapatkan hasil 16 obat kedaluwarsa pada tahun 2022 dengan persentase sebesar 2,18% dari seluruh unit persediaan di gudang induk. Penanganan obat kedaluwarsa di Puskesmas Kecataman Kramat Jati adalah dilakukan karantina 1 bulan sebelum obat tersebut kedaluwarsa untuk mencegah penggunaan obat tersebut. Obat yang telah kedaluwarsa akan dimusnahkan oleh pihak eksternal sesuai dengan prosedur pemusnahan obat dengan memperhatikan keramahan lingkungan.

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The management of pharmaceutical preparations at Puskesmas (Community Health Centers) includes controlling inventory, usage, and the expiration dates of drugs. Expired or damaged drug should not be given to patients as they can cause harmful toxic effects if consumed. Therefore, monitoring of medication expiration dates must be conducted to minimize undesirable outcomes. The objective of monitoring medication expiration dates is to recapitulation the availability of expired medications in the year 2022 and to take necessary actions regarding the expired drugs at Puskesmas Kecamatan Kramat Jati. Monitoring is performed by recapitulating the stock opname (inventory count) of medications every month for evaluation. The results of the monitoring in the year 2022 revealed that there were 16 expired medications, accounting for approximately 2.18% of the entire inventory in the main warehouse. The handling of expired medications at Puskesmas Kecamatan Kramat Jati involves quarantining them one month before their expiration date to prevent their use. The expired medications will be disposed of by external parties following the drug disposal procedures while considering environmental safety."

"This book covers the methods and applications of bioassays in pharmaceutical science to quantify drug activity and evaluate the validity of models. It demonstrates the numerous systems available and that each system interprets the activity of drug molecules in different ways. The authors discuss the various models put forward to link the experimental observations and the events taking place on a cell or molecular level between the drug and experimental object, providing the principal and technological guide for successful research of drug research and clinical therapy."

"This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and analysis of multiple ligand-target interactions. The ready reference opens with a general introduction to the use of mass spectrometry in pharmaceutical screening, followed by a detailed description of recently developed analytical systems for use in the pharmaceutical laboratory.Applications range from simple binding assays to complex screens of biological activity and systems containing multiple targets or ligands, all highly relevant techniques in the early stages in drug discovery, from target characterization to hit and lead finding."

"Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals. LC/MS is an analytical tool that helps the researcher identify the most promising sample early in the selection process, effectively creating a shortcut to finding new drugs. This book is the first to describe LC/MS applications within the context of drug development, including the discovery, preclinical, clinical, and manufacturing phases. In addition to the thorough technical analysis of this tool, LC/MS Applications in Drug Development provides perspective on the significant changes in strategies for pharmaceutical analysis. A process overview of drug development from an analytical point of view is provided along with essential data required to successfully bring a drug to market. The incorporation of LC/MS is illustrated from target to product. Chapters pertaining to the discovery process itself include : proteomics, glycoprotein mapping, natural products dereplication, lead identification screening, open-access LC/MS, in vitro drug screening written for both the analytical chemist who uses LC/MS applications and the pharmaceutical scientist who works with the drugs they produce."